Latest Tyrosine kinase inhibitors Stories
Among patients with a high risk of recurrence of a gastrointestinal stromal tumor following surgery for its removal, patients who received imatinib (a drug to treat certain cancers) for 3 years instead of 1 had improved recurrence-free survival and overall survival.
Drug resistance is a serious problem for cancer patients—over time, a therapy that was once providing some benefit simply stops working. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) recently discovered how cancer cells develop resistance to a drug called MLN4924.
A new study has found that patients with chronic myeloid leukemia (CML) who have not responded to interferon treatments experience long-term benefits when they switch to the targeted drug imatinib.
By reformulating the common cancer drug imatinib (Gleevec®), researchers have eliminated morphine tolerance in rats – an important step toward improving the effectiveness of chronic pain management in patients.
Treatment with three relatively new "targeted" cancer drugs has been linked to a slightly elevated chance of fatal side effects.
- Monstrous in size or character; huge; prodigious; monstrously perverse, savage, cruel, etc.