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Latest University of Pennsylvania School Stories

2011-04-05 22:09:48

JAMA studies identify shift in prescribing patterns and recommend interventions to protect vulnerable populations Two reports by addiction researchers at the University of Pennsylvania School of Medicine and the National Institute on Drug Abuse show a drastic shift in prescribing patterns impacting the magnitude of opioid substance abuse in America. The reports, published in JAMA, recommend a comprehensive effort to reduce public health risks while improving patient care, including better...

2011-04-05 21:22:08

Penn study offers novel drug combination to halt tumor growth Researchers at the University of Pennsylvania School of Medicine may have found a way to turn an adaptive cellular response into a liability for cancer cells. When normal cells are starved for food, they chew up existing proteins and membranes to stay alive. Cancer cells have corrupted that process, called autophagy, using it to survive when they run out of nutrients and to evade death after damage from chemotherapy and other...

2011-04-05 17:44:29

Heart patients share perspectives on deactivation, donation and reuse of devices Each year, more than 100,000 patients in the U.S. undergo implantation of a new implantable cardioverter defibrillator (ICD) for heart rhythm abnormalities. This number constitutes a 20-fold increase over the last 15 years. Current medical guidelines advocate discussion of end of life care of these medical devices, including deactivation, but many patients may not understand their options. Now, researchers at the...

2011-04-04 17:32:54

Current research supports the notion that lifestyle choices influence cardiovascular health, but to what extent specific emotions play is undefined. Now, new research from the University of Pennsylvania School of Medicine has revealed the role that guilt may play as a motivational tool for cardiovascular patients. Penn researchers interviewed 100 adult cardiology outpatients about the role that guilt plays in their adherence to instructions given by their physicians and as part of their views...

2011-04-02 02:06:35

New biomarker for tau-related brain disorders? Researchers at the University of Pennsylvania School of Medicine have determined that a well-known chemical process called acetylation has a previously unrecognized association with one of the biological processes associated with Alzheimer's disease and related disorders. The findings were published in the latest issue of Nature Communications. Tau is one of the primary disease proteins associated with a suite of neurodegenerative diseases. Tau...

2011-03-22 00:41:39

Patients treated on weekends have greater chance of survival Patients who've been hurt in car or bike crashes, been shot or stabbed, or suffered other injuries are more likely to live if they arrive at the hospital on the weekend than during the week, according to new University of Pennsylvania School of Medicine research published in the March 21 issue of Archives of Surgery. The findings, which also showed that trauma patients who present to the hospital on weeknights are no more likely to...

2011-03-15 10:27:00

Listed Among the Top Five Medical Schools Nationally for 14th Straight Year PHILADELPHIA, March 15, 2011 /PRNewswire-USNewswire/ -- For the second consecutive year, the University of Pennsylvania School of Medicine ranks #2 among research-oriented medical schools in the United States, according to U.S.News & World Report's annual survey. The annual survey of the nation's 126 fully accredited medical schools and twenty schools of osteopathic medicine also places Penn in the top ten...

2011-03-02 20:32:17

Metabolic function for tumor suppressor points to new cancer therapeutics The gene for the protein p53 is the most frequently mutated in human cancer. It encodes a tumor suppressor, and traditionally researchers have assumed that it acts primarily as a regulator of how genes are made into proteins. Now, researchers at the University of Pennsylvania School of Medicine show that the protein has at least one other biochemical activity: controlling the metabolism of the sugar glucose, one of...

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2011-02-08 07:47:23

So-called barrier sites -- the skin, gut, lung "“ limit the inner body's exposure to allergens, pollutants, viruses, bacteria, and parasites. Understanding how the immune system works in these external surfaces has implications for understanding such inflammatory diseases as asthma, psoriasis, IBD, and food allergies, all of which occur at the body's barriers. David Artis, PhD, professor of Microbiology at the University of Pennsylvania School of Medicine, and Gregory F. Sonnenberg, a...

2011-02-03 01:30:17

A simple test performed at the sideline of sporting events can accurately detect concussions in athletes, according to study by researchers at the University of Pennsylvania School of Medicine. Current sideline tests can leave a wide amount a brain function untested following concussion. Penn researchers showed that this simple test was superior to current methods and accurately and reliably identified athletes with head trauma. The study appears online now in Neurology. The one-minute test...


Word of the Day
ramage
  • Boughs or branches.
  • Warbling of birds in trees.
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