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Latest Unsolved problems in neuroscience Stories

2011-10-12 11:30:23

Melatonin, best known for its role in sleep regulation, delayed the onset of symptoms and reduced mortality in a mouse model of Huntington's disease, say researchers at the University of Pittsburgh School of Medicine and Harvard Medical School. Their findings, published today in the Journal of Neuroscience, show for the first time that certain receptors for the hormone reside in the mitochondria, and that there are fewer of them both in affected mice and human brains. Huntington's disease...

2011-10-11 10:05:44

Addressing the earliest stages of Alzheimer's disease, before a patient shows outward signs of cognitive problems, has sometimes been a challenge for physicians and researchers, in part because they have not been using common and specific terms to describe the disease's initial phases. A Mayo Clinic study recommends adding categories to more effectively identify and treat people and give researchers standard definitions to work with. The study is published in this month's issue of the Annals...

2011-10-05 15:15:42

Johns Hopkins-led research suggests levels of certain fats in blood might predict rate of cognitive decline A team of scientists, led by Johns Hopkins researchers, say they may have found a way to predict how quickly patients with Alzheimer´s disease (AD) will lose cognitive function by looking at ratios of two fatty compounds in their blood. The finding, they say, could provide useful information to families and caregivers, and might also suggest treatment targets for this...

2011-10-04 05:54:10

(Ivanhoe Newswire) — Huntington´s disease is a devastating genetic disorder that causes degeneration of nerve cells in the brain. It affects more than 15,000 Americans, and at least 150,000 are at risk of developing the incurable disease.  Now, researchers have identified a transcriptional biomarker that may help in the monitoring of disease activity and in the evaluation of new medications. The research, which is a collaboration between the laboratory of Clemens Scherzer,...

2011-10-03 07:00:00

Corporate partners team up with local ALS Association to form walk teams and increase sponsorship levels. Phoenix, AZ (PRWEB) October 03, 2011 Valley Toyota Dealers, Quicken Loans and Fathead have joined the fight against ALS by sponsoring The Scottsdale Walk to Defeat ALS on Saturday, October 22, 2011 benefitting The ALS Association Arizona Chapter. The walk will be held for the second year at Scottsdale Stadium, where patients along with their families and friends will make a 2.5-mile...

2011-10-03 22:23:47

Laser technique allows detailed view of the early minutes of amyloid aggregate formation -- implications for Alzheimer's disease drug discovery Researchers at the University of Toronto Scarborough (UTSC) and Osaka University applied a new approach to take a close look at amyloid plaque formation, a process that plays important roles in Alzheimer's disease. The technique would greatly aid the development and screening for novel therapeutics that can manipulate the formation of the toxic...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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