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Latest Unsolved problems in neuroscience Stories

2012-06-04 17:24:16

-It acts simultaneously on several targets in the brain -In vitro studies reveal a reduction in the ß-amyloid peptide aggregation, involved in the disease, and a boost in cognitive function -It could lead the development of more efficient drugs than those currently used Researchers at Universitat Autònoma de Barcelona (UAB), the Spanish National Research Council (CSIC) and the University of Barcelona (UB) have developed a multitarget molecule, ASS234, which...

2012-06-04 04:21:37

(Ivanhoe Newswire) - 5.4 million Americans suffer from Alzheimers and 3 million from Parkinson's disease. Doctors who treat patients with these among other neurodegenerative conditions believe that the diseases are spreading though their patients' brains. The stages of both Alzheimers and Parkinson's disease show these pathological effects. Until recently, only in prion disease had this spread been shown, resulting in proof that the agent of spread is the prion protein. More recently,...

2012-05-30 10:03:52

Scientists from The Scripps Research Institute and Pfizer Inc. have published a new study showing how a new drug called tafamidis (Vyndaqel®) works. Tafamidis, approved for use in Europe and currently under review by the US Food and Drug Administration (FDA), is the first medication approved by a major regulatory agency to treat an amyloid disease, a class of conditions that include Alzheimer's. Tafamidis treats a deadly nerve disease caused by transthyretin (TTR) amyloid fibril...

2012-05-23 17:01:47

Pathological aging (PA) is used to describe the brains of people which have Alzheimer's disease (AD)-like pathology but where the person showed no signs of cognitive impairment whilst they were alive. New research, published in BioMed Central's open access journal Alzheimer's Research & Therapy, shows that PA and AD brains contain similar amyloid β (Aβ) plaques and that while on average AD brains contain more Aβ there was considerable overlap in Aβ subtypes. These...

2012-05-16 11:04:20

UCLA researchers may have found a key to determining which Parkinson's disease patients will experience a more rapid decline in motor function, sparking hopes for the development of new therapies and helping identify those who could benefit most from early intervention. In a study published May 15 in the peer-reviewed online journal PLoS ONE, the researchers found that Parkinson's sufferers who possess two specific variants of a gene known to be a risk factor for the disease had a...

2012-05-16 05:00:22

(Ivanhoe Newswire) — Though there is no known cure for Parkinson´s disease, there are means to control the symptoms. Researchers at UCLA may have found a way to determine which patients will experience a more rapid decline in motor function, which is potentially beneficial in developing new therapies and identifying who can benefit the most from early intervention. In a small study with 233 patients, the researchers discovered that people with Parkinson´s who possess two...

2012-05-14 21:10:36

A new study led by Brown University researchers reports that percutaneous endoscopic gastric (PEG) feeding tubes, long assumed to help bedridden dementia patients stave off or overcome pressure ulcers, may instead make the horrible sores more likely to develop or not improve. The analysis of thousands of nursing home patients with advanced dementia appears in the May 14 edition of the Archives of Internal Medicine. "This study provides new information about the risks of feeding tube...


Word of the Day
snash
  • To talk saucily.
  • Insolent, opprobrious language; impertinent abuse.
This word is Scots in origin and probably imitative.