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Latest Unsolved problems in neuroscience Stories

2012-04-25 12:00:45

University of California, San Diego scientists have used powerful computational tools and laboratory tests to discover new support for a once-marginalized theory about the underlying cause of Parkinson´s disease. The new results conflict with an older theory that insoluble intracellular fibrils called amyloids cause Parkinson´s disease and other neurodegenerative diseases. Instead, the new findings provide a step-by-step explanation of how a “protein-run-amok”...

2012-04-24 10:02:51

A study that examined the relationship between two cerebrospinal fluid proteins associated with Alzheimer disease in clinically and cognitively normal older patients suggests that amyloid-β (Αβ)-associated clinical decline was linked to the presence of elevated phospho-tau (p-tau), according to a report published Online First by Archives of Neurology, a JAMA Network publication. Identifying clinically normal older individuals destined to develop Alzheimer disease (AD)...

2012-04-23 06:24:34

The annual three day, 270 mile bike ride continues its commitment to fund research to end ALS CAMBRIDGE, Mass., April 23, 2012 /PRNewswire-USNewswire/ -- The ALS Therapy Development Institute (ALS TDI) Tri-State Trek is celebrating its 10th anniversary this year. A three-day, 270 mile bike ride from Boston to Greenwich, CT, the Trek raises money and awareness to end amyotrophic lateral sclerosis (ALS), better known as Lou Gehrig's disease. (Logo:...

2012-04-23 02:28:11

NEW YORK, April 23, 2012 /PRNewswire/ -- Oligomerix, Inc., a privately held company pioneering the development of disease modifying therapeutics for Alzheimer's disease and related neurodegenerative disorders, announced today the completion of approximately $2 million in Series A financing, which includes both issuance of new convertible preferred shares and debt conversion. Wheatley MedTech Partners, L.P., Wheatley New York Partners LP and Durand Venture Associates, LLC were the lead...

2012-04-20 12:05:18

Forced body cooling known as therapeutic hypothermia has reduced in-hospital deaths among sudden cardiac arrest patients nearly 12 percent between 2001 and 2009, according to a Mayo Clinic study being presented at the upcoming American Academy of Neurology 2012 Annual Meeting in New Orleans. The research is among several Mayo abstracts that will be discussed at the conference. The goal of therapeutic cooling is slowing the body's metabolism and preventing brain damage or death. It is...

2012-04-17 05:40:43

(Ivanhoe Newswire)-- Having a loved one diagnosed with Alzheimer's disease can be devastating, especially without warning. Now a recent study shows how doctors may be able to diagnose the disease earlier. Early detection would give more time for family members to prepare for the devastating disease. Currently, Alzheimer's disease can only be definitively confirmed through the detection of amyloid plaques and/or tangles in the brain during autopsy after death or with a brain tissue...

2012-04-16 23:38:46

Dementia is a frequent complication of Parkinson's disease (PD), but it is clinically impossible to distinguish PD dementia (PDD), which develops from the progression of the Lewy body pathology that underlies PD, from PD with coexistent Alzheimer's disease (PDAD). Both have similar characteristics. A team of scientists has found that PDAD patients have much denser accumulations of amyloid plaques in the striatal area of the brain than PDD patients. The results suggest that recently developed...

2012-04-16 12:53:12

Use of a new drug to detect the beta-amyloid plaques in the brain that are hallmark signs of Alzheimer's disease may help doctors diagnose the disease earlier, according to research that will be presented as part of the Emerging Science program (formerly known as Late-Breaking Science) at the American Academy of Neurology's 64th Annual Meeting in New Orleans April 21 to April 28, 2012. Currently, Alzheimer's disease can only be definitively confirmed through the detection of amyloid...

2012-04-10 05:04:35

(Ivanhoe Newswire) -- Pick up a book! Reading and writing now may contribute to prolonged memory retention and thinking abilities when you´re older. In the first of two recent studies conducted by Robert S. Wilson, PhD of Rush University Medical Center in Chicago, memory decline has been linked to the two-and-a-half years before death, and according to the second study, an active mind just may be the best means of prevention. Wilson´s first study was conducted on 174 individuals,...

2012-04-05 09:22:39

New research finds that a person's memory declines at a faster rate in the two- and-a-half years before death than at any other time after memory problems first begin. A second study shows that keeping mentally fit through board games or reading may be the best way to preserve memory during late life. Both studies are published in the April 4, 2012, online issue of Neurology®, the medical journal of the American Academy of Neurology. For the study, 174 Catholic priests, nuns and monks...