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Latest Unsolved problems in neuroscience Stories

2012-04-02 15:55:54

Findings may have wider implications for other neurodegenerative diseases, such as Alzheimer's Rutgers scientists think they have found a way to prevent and possibly reverse the most debilitating symptoms of a rare, progressive childhood degenerative disease that leaves children with slurred speech, unable to walk, and in a wheelchair before they reach adolescence. In today's online edition of Nature Medicine, Karl Herrup, chair of the Department of Cell Biology and Neuroscience in the...

2012-03-30 08:14:25

Investigators from the University of Amsterdam, Netherlands, have shown that in most elderly patients invasive and expensive techniques, i.e. lumbar puncture and PET scan, are not useful to establish the diagnosis of Alzheimer's disease. They arrived at this conclusion after analysis of data from the Alzheimer's Disease Neuroimaging Initiative (ADNI), a large collaborative research project of medical centers in the USA and Canada. The Dutch researchers divided the ADNI sample into two...

2012-03-28 00:58:55

A new study shows that when we test older adults in a medical or research setting, it produces a stress response that reduces their memory Your mother had a doctor's appointment for a memory test. The results are conclusive: she presents with the first signs of Alzheimer type dementia. Now, to get to her appointment, your mother, who is no longer used to driving in town, took her car, looked for a parking space for 15 minutes, got lost in a labyrinth of one-way streets, had never used...

2012-03-28 00:00:17

Data supports links between AD and diabetes, according to new study in the Journal of Alzheimer's Disease Alzheimer's disease is the sixth leading cause of death in the United States and the only cause of death among the top 10 in America without a way to prevent, cure or even slow its progression, according to the Alzheimer's Association. Today, 5.4 million Americans are living with the disease, and another American develops it every 69 seconds. Unfortunately, many Alzheimer's disease...

2012-03-27 13:51:47

A meta-analysis of previously published studies found that the ratio of blood plasma amyloid-β (Aβ) peptides Aβ42:Aβ40 was significantly associated with development of Alzheimer disease and dementia, according to a report published Online First by Archives of Neurology, one of the JAMA/Archives journals. "Plasma levels of amyloid-β (Aβ) peptides have been a principal focus of the growing literature on blood-based biomarkers, but studies to date have varied in...

2012-03-27 09:03:06

A breakthrough using cutting-edge stem cell research could speed up the discovery of new treatments for motor neurone disease A breakthrough using cutting-edge stem cell research could speed up the discovery of new treatments for motor neurone disease (MND). The international research team has created motor neurones using skin cells from a patient with an inherited form of MND. The study discovered that abnormalities of a protein called TDP-43, implicated in more than 90 per cent of...

2012-03-27 08:40:34

Repeated stress triggers the production and accumulation of insoluble tau protein aggregates inside the brain cells of mice, say researchers at the University of California, San Diego School of Medicine in a new study published in the March 26 Online Early Edition of the Proceedings of the National Academy of Sciences. The aggregates are similar to neurofibrillary tangles or NFTs, modified protein structures that are one of the physiological hallmarks of Alzheimer's disease. Lead author...

2012-03-24 04:41:53

An international team of researchers have developed a new method for measurement of aggregated beta-amyloid — a protein complex believed to cause major nerve cell damage and dysfunction in Alzheimer's disease. The new method might facilitate diagnosis and detection as well as development of drugs directed against aggregated beta-amyloid. Alzheimer's disease (AD) is the most common cause of memory decline and dementia. According to the Alzheimer World Report 2011, today around 36...


Word of the Day
monteith
  • A large punch-bowl of the eighteenth century, usually of silver and with a movable rim, and decorated with flutings and a scalloped edge. It was also used for cooling and carrying wine-glasses.
  • A kind of cotton handkerchief having white spots on a colored ground, the spots being produced by a chemical which discharges the color.
This word is possibly named after Monteith (Monteigh), 'an eccentric 17th-century Scotsman who wore a cloak scalloped at the hem.'
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