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Latest Uric acid Stories

2011-08-16 23:25:47

As an alternative to a conventional treatment for gout that some patients may not respond to, patients with severe, chronic gout who received the medication pegloticase for 6 months had greater improvement in measures of uric acid levels as well as physical function and quality of life, according to a study in the August 17 issue of JAMA. Long-term urate (a salt derived from uric acid) lowering therapy in gout aims to maintain concentrations of uric acid (UA) below a certain level. However,...

2011-08-16 23:21:17

Injections of pegloticase, a modified porcine enzyme, can produce significant and sustained clinical improvements in 2 out of 5 patients with chronic gout that is resistant to conventional therapies, researchers report in the August 17, 2011, issue of JAMA. In two controlled clinical trials, pegloticase rapidly lowered high levels of uric acid, the biochemical abnormality in gout, and kept it in the normal range for six months or more in 42 percent of patients receiving the drug every two...

2011-08-16 15:01:00

EAST BRUNSWICK, N.J., Aug. 16, 2011 /PRNewswire/ -- Savient Pharmaceuticals, Inc. (NASDAQ: SVNT) today announced that results from two pivotal KRYSTEXXA® (pegloticase) Phase III clinical studies in patients with refractory chronic gout (RCG) have been published in The Journal of the American Medical Association (JAMA). The data demonstrated that treatment with KRYSTEXXA resulted in significant and sustained reductions in uric acid levels along with clinical...

2011-08-05 07:30:00

SAN DIEGO, Aug. 5, 2011 /PRNewswire/ -- Ardea Biosciences, Inc. (Nasdaq: RDEA), a biotechnology company focused on the development of small-molecule therapeutics for the treatment of serious diseases, today reported recent accomplishments and financial results for the second quarter and six months ended June 30, 2011. "Since our last quarterly update, we presented exciting initial results from the ongoing extension portion of our Phase 2b trial of lesinurad demonstrating high rates of...

2011-07-29 06:26:57

(Ivanhoe Newswire) -- New research suggests the prevalence of gout has risen over the past 20 years in the United States. Gout is an inflammatory arthritis that is triggered by crystallization of uric acid within the joints. The condition causes severe pain and swelling. Gout is linked to metabolic syndrome -- a group of health conditions characterized by obesity, insulin resistance, high blood pressure and blood lipid problems. In this new study, researchers found gout now affects about 8.3...

2011-07-28 17:22:21

Increase in obesity and hypertension are likely contributors A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans. Prevalence of increased uric acid levels (hyperuricemia) also rose, affecting 43.3 million (21%) adults in the U.S. Greater frequency of obesity and hypertension may be associated with the jump in prevalence rates according to the findings now available in Arthritis & Rheumatism, a journal...

2011-07-28 12:49:08

In humans, inherited mutations in a gene called HPRT1 lead to very specific self-destructive behavior. Boys with Lesch-Nyhan disease experience uncontrollable urges to bite their fingers, slam their arms into doorways and otherwise harm themselves. Puzzlingly, mice with mutations in the same gene don't behave differently than normal mice. Researchers at Emory University School of Medicine have identified a gene related to HPRT1, present in humans but not in mice that helps explain this...

2011-07-25 05:25:00

BRADLEY, Ill., July 25, 2011 /PRNewswire/ -- During the summer, millions of Americans head to the golf courses. Unfortunately, many people miss out altogether due to painful inflammation caused by elevated uric acid levels from an unhealthy diet.(1) Defend against uric acid build-up with safe, all natural Goutch! (TM) by Redd Remedies®.(www.reddremedies.com) "During summer, golfers' minds turn to long drives down the fairway, but summer is also a season of indulgences,"...

2011-06-28 05:30:00

WASHINGTON and DEERFIELD, Ill., June 28, 2011 /PRNewswire/ -- Men's Health Network (MHN) and Takeda Pharmaceuticals North America, Inc., today announced a partnership to launch the "Gout Pit Stop," an educational campaign to raise awareness about gout, a type of arthritis that affects approximately 8.3 million people in the U.S. and is the most common form of inflammatory arthritis in men. Launched just before one of the biggest events of the year on the racing calendar and during Men's...

2011-05-26 14:05:33

A pan-European study of 755 gout patients found that prevalence of self-reported gout was highest in the UK (2.2%) and lowest in France (0.76%). French, German and British gout patients all had lower quality of life scores, and had significant work and social impairment compared to controls (p<0.05 for all comparisons). Interestingly, patients in these countries also had more hypertension, diabetes, congestive heart failure and renal disease (p=0.05) compared to healthy controls. Abstract...


Word of the Day
drawcansir
  • A blustering, bullying fellow; a pot-valiant braggart; a bully.
This word is named for Draw-Can-Sir, a character in George Villiers' 17th century play The Rehearsal.
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