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Last updated on April 18, 2014 at 14:37 EDT

Latest V(D)J recombination Stories

2014-02-19 08:34:21

BURNABY, BC, Feb. 19, 2014 /PRNewswire/ - Innovative Targeting Solutions Inc. (ITS), the developer of the next generation protein engineering technology (HuTARG(TM)), today announced the extension of its research collaboration with Amgen Inc. (Thousand Oaks, CA) that allows Amgen to internalize ITS' HuTARG(TM) technology. Under the terms of the agreement, ITS is entitled to specific license payments and development milestones. About Innovative Targeting Solutions Inc. Founded in...

2013-08-21 12:28:02

Mirrors the influence of gut bacteria over T-cells, suggests new paradigm for B-cell development BOSTON, Aug. 21, 2013 /PRNewswire-USNewswire/ -- Gut bacteria exert a dramatic, systemic effect on the development of the immune system's B-lymphocytes, according to a new mouse study by researchers at Boston Children's Hospital. While influences of gut bacteria on T-lymphocytes have been noted before, this is the first time that researchers have documented early B-cell development in...

2009-05-21 12:53:31

A new study published online in Nature Immunology ahead of the June 2009 print issue has found that homologous immunoglobulin (lg) alleles pair up in the nucleus at stages that coincide with V(D)J recombination of the heavy and light chain (Igh and Igk) loci. Researchers led by Jane A. Skok Ph.D., assistant professor in the Department of Pathology at NYU School of Medicine and a member of the NYU Cancer Institute, showed that the V(D)J recombinase, which consists of the RAG1 and RAG2...