Latest Vaccinia Stories
Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract.
How well people are protected by the smallpox vaccine depends on more than the quality of the vaccination: individual genes can alter their response.
Researchers recently discovered how poxviruses, viruses that contain DNA, can change quickly; in particular, they have an “accordion-like” way of viral adaption to fight against host viral defenses.
Infectious diseases—both old and new—continue to exact a devastating toll, causing some 13 million fatalities per year around the world.
Very recently, researchers discovered an important population of immune cells called memory T cells living in parts of the body that are in contact with the environment (e.g., skin, lung, GI tract).
TREM Rx, Inc., a biotechnology company with a proprietary technology platform for novel vaccines delivered to the skin, announced today the results of an in vivo preclinical study that shows, for the first time, that powerful cells of the immune system called TREMs (T Resident Effector Memory cells) prevalent in the skin can mediate a protective immune response that is far stronger than memory T cells that circulate in the bloodstream.
The observation that milkmaids are frequently infected with cowpox but rarely catch smallpox is generally credited to the English doctor Edward Jenner.
Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family. It is well-known for its role in eradicating smallpox. It was the first human disease to to successfully be eradicated by science. The World Health Organization was the one who completed the endeavor. The vaccinia virus saw renewed interest in the early 21st century due to concerns about the smallpox virus being used as an agent for bioterrorism. They can be divided into four types:...
The Cowpox virus causes a skin disease known as cowpox. It is related to the vaccinia virus and gained its name because it spread by dairymaids touching the udders of infected cows. It manifests as red blisters. It is similar to smallpox although much milder and was actually the basis of the first smallpox vaccine. A person who recovers from cowpox is immune to smallpox. In 1980 the World Health Organization announced that smallpox was the first disease to be eradicated world wide by a...