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Latest Vaccinia Stories

2013-09-26 09:48:37

Many viruses and bacteria infect humans through mucosal surfaces, such as those in the lungs, gastrointestinal tract and reproductive tract. To help fight these pathogens, scientists are working on vaccines that can establish a front line of defense at mucosal surfaces. Vaccines can be delivered to the lungs via an aerosol spray, but the lungs often clear away the vaccine before it can provoke an immune response. To overcome that, MIT engineers have developed a new type of nanoparticle...

2013-04-18 19:22:14

How well people are protected by the smallpox vaccine depends on more than the quality of the vaccination: individual genes can alter their response, Mayo Clinic research shows. The findings, gathered using sophisticated genomic screening, appear in today's online issue of the journal Genes and Immunity. "We were looking into the intercellular reactions that occur when vaccinated and unvaccinated persons are exposed to and infected with smallpox virus. We were able to use blood samples...

Poxviruses Adapt Quickly To Fight Host Of Viral Defenses
2012-08-17 12:28:52

Connie K. Ho for redOrbit.com — Your Universe Online Researchers recently discovered how poxviruses, viruses that contain DNA, can change quickly; in particular, they have an “accordion-like” way of viral adaption to fight against host viral defenses. Poxviruses, which include smallpox, can lead to a number of diseases in both humans and animals. They are seen as harmful, as they can pass through the species barrier with low mutation rates. Recently, there has been...

2012-05-09 21:12:12

Infectious diseases–both old and new–continue to exact a devastating toll, causing some 13 million fatalities per year around the world. Vaccines remain the best line of defense against deadly pathogens and now Kathryn Sykes and Stephen Johnston, researchers at Arizona State University´s Biodesign Institute, along with co-author Michael McGuire from the University of Texas Southwestern Medical Center are using clever functional screening methods to attempt to speed new...

2012-03-01 01:58:17

Very recently, researchers discovered an important population of immune cells called memory T cells living in parts of the body that are in contact with the environment (e.g., skin, lung, GI tract). How these "resident" memory T cells are generated was unknown, and their importance with regard to how our immune system remembers infection and how it prevents against re-infection is being studied intensively. Now, a study by a Brigham and Women's Hospital (BWH) research team led by Xiaodong...

2012-03-01 01:54:36

Research shows for the first time that resident memory T cells prevalent in the skin are more protective in fighting infection than central memory T cells in the bloodstream TREM Rx, Inc., a biotechnology company with a proprietary technology platform for novel vaccines delivered to the skin, announced today the results of an in vivo preclinical study that shows, for the first time, that powerful cells of the immune system called TREMs (T Resident Effector Memory cells) prevalent in the...

2011-09-14 13:22:08

The observation that milkmaids are frequently infected with cowpox but rarely catch smallpox is generally credited to the English doctor Edward Jenner.  Although Jenner might not have been the first person to notice the correlation, he was the first to make use of it:  in 1796 he “vaccinated” children with material from cowpox blisters and showed that they became immune to smallpox.  Jenner´s work led directly to the development of a smallpox vaccine and less...


Latest Vaccinia Reference Libraries

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2011-02-23 21:18:56

Vaccinia virus (VACV or VV) is a large, complex, enveloped virus belonging to the poxvirus family. It is well-known for its role in eradicating smallpox. It was the first human disease to to successfully be eradicated by science. The World Health Organization was the one who completed the endeavor. The vaccinia virus saw renewed interest in the early 21st century due to concerns about the smallpox virus being used as an agent for bioterrorism. They can be divided into four types:...

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2011-01-11 14:17:29

The Cowpox virus causes a skin disease known as cowpox. It is related to the vaccinia virus and gained its name because it spread by dairymaids touching the udders of infected cows. It manifests as red blisters. It is similar to smallpox although much milder and was actually the basis of the first smallpox vaccine. A person who recovers from cowpox is immune to smallpox. In 1980 the World Health Organization announced that smallpox was the first disease to be eradicated world wide by a...

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Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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