Latest Vacuole Stories

Programmed cell death (PCD) is a highly regulated process that occurs in all animals and plants as part of normal development and in response to the environment. New research published in BioMed Central's open access journal BMC Plant Biology is the first to document the physiological events in the lace plant (Aponogeton madagascariensis) which occur via PCD to produce the characteristic holes in its leaves. The aquatic lace plant, endemic to Madagascar, uses PCD to generate holes in its...

RUB biologists decipher the function of the metal-binding molecule nicotianamine In order to survive, plants should take up neither too many nor too few minerals from the soil. New insights into how they operate this critical balance have now been published by biologists at the Ruhr-Universität in a series of three papers in the journal The Plant Cell. The researchers discovered novel functions of the metal-binding molecule nicotianamine. "The results are important for sustainable...

Bacteria are able to build camouflaged homes for themselves inside healthy cells - and cause disease - by manipulating a natural cellular process. Purdue University biologists led a team that revealed how a pair of proteins from the bacteria Legionella pneumophila, which causes Legionnaires disease, alters a host protein in order to divert raw materials within the cell for use in building and disguising a large structure that houses the bacteria as it replicates. Zhao-Qing Luo, the...

Discovery of subcellular processing location and target signal of cyclotide kalata B1 Many plants produce compounds that serve as a defense against predators or pathogens. Some are also used by humans for a variety of beneficial purposes, such as in medicines. As recently as the early 1990s, a unique class of proteins previously unknown to science, the cyclotides, was discovered. First noted through African tribal use as a tea given to speed up delivery during childbirth, cyclotides have...

A new technique developed by researchers at RIKEN has clarified the location and dynamics of specific metabolites in a single cell of the alga Chara australis. The findings reveal that these metabolites are regulated and fluctuate under stress conditions, providing insight into previously-unknown functions of the vacuole in cellular processes. Metabolites, the intermediates and products of chemical reactions that sustain all living organisms, play a central role in cellular processes...

Research by University of Warwick's School of Life Sciences has opened up a new path to produce water efficient seeds that will be a significant tool to help create drought resistance, and ensure global food security.  The research not only provides the best map to date of the key protein that appears to be the principal gateway for water intake during seed germination - it also actually provides the right map as it appears much of the research to date was focussed on a much less relevant...

'Splitting protein' shown to play crucial role in formation of plant vacuolesBite into a sour apple and you destroy them "“ plant cell vacuoles. Even though these vacuoles make up the largest volume of plant cells, only little was known about how these cellular storehouses form and how the substances stored in them find their way there. Scientists at the Technische Universitaet Muenchen (TUM) have now discovered a new protein essential to the formation of vacuoles. In the process they...

It's important to finish what you start, say Jeong-Sun Ju and researchers from Washington University School of Medicine, St. Louis. In the December 14, 2009 issue of the Journal of Cell Biology, Ju et al. reveal how a mutant ATPase blocks autophagy partway through to cause a multi-tissue degenerative disease.Mutations in VCP, a member of the AAA ATPase family, cause inclusion body myopathy, Paget's disease of the bone, and frontotemporal dementia (IBMPFD), a rare disorder that mainly affects...

By Guo, Woei-Jiun Ho, Thun-Hua David Plant HVA22 is a unique abscisic acid (ABA)/stress-induced protein first isolated from barley (Hordeum vulgare) aleurone cells. Its yeast homolog, Yop1p, functions in vesicular trafficking and in the endoplasmic reticulum (ER) network in vivo. To examine the roles of plant HVA22, barley HVA22 was ectopically expressed in barley aleurone cells. Overexpression of HVA22 proteins inhibited gibberellin (GA)-induced formation of large digestive vacuoles, which...

STORRS, Conn. "“ A team of scientists led by University of Connecticut plant biologist Roberto Gaxiola has discovered an overlooked genetic key to generating plants that are more productive, more drought resistant and can grow in soils low in nutrients. Their work is the first to successfully test in cells a 30-year-old hypothesis that explains the movement of a primary growth and development hormone through plants and is expected to prompt biology textbooks to be rewritten.The researchers...