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Last updated on April 21, 2014 at 5:21 EDT

Latest Veronika Sexl Stories

2012-01-30 10:35:30

About one in five or six cases of adult leukemia in Western populations relates to so-called chronic myeloid leukemia, or CML.  Treatment of CML usually relies on inhibitors of the abnormal protein that causes the condition but some patients do not respond to treatment and efforts are underway to develop a supplementary approach, targeting the so-called JAK2 kinase.  Recent results from the groups of Veronika Sexl at the University of Veterinary Medicine, Vienna (Vetmeduni Vienna)...

2011-11-08 15:18:16

Although Burkitt´s lymphoma is thankfully fairly rare in the general population, it is the most common form of malignancy in children in Equatorial Africa and is very frequent in immunocompromised persons, such as those suffering from AIDS.  It is invariably accompanied by an increase in the expression of a particular gene, the so-called c-myc gene.  An increased level of c-myc is not usually enough to cause cancer and most patients also have alterations to another gene. ...

2011-02-22 21:15:00

Our immune systems contain three fundamentally different types of cell:  B-cells, T-cells and the mysteriously named Natural Killer cells (NK cells), which are known to be involved in killing tumor cells and other infected cells.  Experiments to investigate the function of NK cells have proven difficult to interpret because the interactions between the various components of the immune system make it almost impossible to isolate effects of individual cell types.  This has...

2010-03-03 13:28:02

An international team of scientists studying acute forms of Leukaemia have identified a new drug target to inhibit the genes which are vital for the growth of diseased cells. The research, reported in EMBO Molecular Medicine, reveals how leukaemia cells become 'addicted' to genes, which if targeted could prevent diseased cells from developing. The team, led by Dr Veronika Sexl from the University of Vienna, carried out their research on acute lymphoid leukaemia (ALL) and chronic myelogenous...