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Latest Vioxx Stories

2012-05-02 21:20:19

After nearly 13 years of study and intense debate, a pair of new papers from the Perelman School of Medicine, at the University of Pennsylvania have confirmed exactly how a once-popular class of anti-inflammatory drugs leads to cardiovascular risk for people taking it. It has been almost eight years since Vioxx® was withdrawn by Merck from the market, provoking an intense controversy about the role inhibitors of the enzyme COX-2 play in causing heart attacks and strokes. Since then,...

Merck To Pay $950M To Settle Vioxx Dispute
2011-11-23 06:47:38

Drugmaker Merck & Co will pay $950 million to settle criminal and civil charges that it marketed its Vioxx for an unapproved use, the U.S. Justice Department said on Tuesday. The fine ends a long-running probe into Merck's promotion of the painkilling drug, which was withdrawn from the market in September 2004 after being linked to increased risks of heart attacks and strokes. The department said Merck would pay $321.6 million in criminal fines and $628.4 million as a civil...

2011-11-05 22:00:00

Falls and fractures among senior citizens have increased since rofecoxib (Vioxx®) was removed from the market in 2004, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago. Chicago, Illinois (PRWEB) November 05, 2011 Falls and fractures among senior citizens have increased since rofecoxib (Vioxx®) was removed from the market in 2004, according to research presented this week at the American College of Rheumatology...

2011-02-23 13:31:31

Analysis highlights cardiovascular risk of fluid retention New research shows that medications which have raised safety concerns over heart attack and stroke risks may not have gotten approval from the Food and Drug Administration (FDA) if the cardiovascular effects of fluid retention had been better understood. Fluid retention may explain the increased risk of heart attacks and strokes of medications such as Vioxx®, Bextra®, and...

2010-09-14 01:13:35

A research team from the University of California, Davis and Peking University, China, has discovered a novel mechanism as to why the long-term, high-dosage use of the well-known arthritis pain medication, Vioxx, led to heart attacks and strokes. Their groundbreaking research may pave the way for a safer drug for millions of arthritis patients who suffer acute and chronic pain. Using metabolomic profiling to analyze murine (rodent) plasma, the scientists discovered that Vioxx causes a...

2009-11-23 16:34:15

Provides lessons for post-market pharmaceutical safety Evidence of cardiovascular risks associated with taking Vioxx, the popular, nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer, Merck & Co. Inc., voluntarily pulled the drug from the market. Led by Joseph Ross, MD, MHS, Assistant Professor of Geriatrics and Palliative Medicine and of Medicine at Mount Sinai School of Medicine, a team of six investigators analyzed 30...

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2008-10-14 14:49:06

Researchers said on Monday that a long-term analysis of people who took the arthritis drug Vioxx confirms it doubles the risk of strokes and heart attacks, but this risk goes away a year after people stop taking it. They also said other drugs in the same class of painkillers known as Cox-2 inhibitors may cause similar harm. "The good news is the data suggests that the risk doesn't persist forever. The risk goes back toward normal after a year of follow up," said Dr. Robert Bresalier of the...

2008-09-11 03:00:08

By Brezis, Mayer Belmaker, R H Mayer Brezis, MD, MPH Center for Clinical Quality & Safety, Hadassah Medical Center & School of Public Health, The Hebrew University of Jerusalem, Israel Abstract: A landmark paper on Game Theory showed that individual maximization of profit necessarily endangers the public good, and since the problem has no technical solution, "it requires a fundamental extension in morality" (1). We propose here that public health, as a public good, now emerges as...

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2008-08-20 10:31:44

The primary purpose of a 1999 clinical study that Merck & Co Inc said was done to test side effects of Vioxx, was actually to support a marketing campaign before the now-withdrawn painkiller's launch, according to U.S. researchers. The real aim of the study, called Advantage, was to promote prescription of the new medicine when it became available -- a so-called "seeding" project -- the researchers said on Tuesday. The research team based its conclusions on an extensive trawl of Merck...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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