Latest Viral hepatitis Stories
Saint Luke's Liver Disease Management Center says testing is key to saving lives, 'silent infection' rampant among baby boomers KANSAS CITY, Mo., May 21, 2013 /PRNewswire-USNewswire/ -- If you're a baby boomer, you may not know that odds are high that you're carrying the hepatitis C virus, putting yourself at risk for illness that can range from minor to life threatening. Hepatitis C is a contagious disease affecting primarily the liver, caused by the hepatitis C virus (HCV). The...
CDC estimates “silent killer” affects five million Americans. Camden, NJ (PRWEB) May 13, 2013 When 57-year-old Vineland resident Rafael Roman was hospitalized at a South Jersey medical center with liver failure one year ago, his doctor told him there was nothing that could be done for him. “He told me I’d be lucky to make it to the end of the week,” says Roman, a father of five. “I said to him, ‘You know it’s Thursday, right?’” Fortunately,...
RARITAN, N.J., May 13, 2013 /PRNewswire/ -- Janssen Research & Development, LLC (Janssen) announced today that the U.S. Food and Drug Administration (FDA) has granted Priority Review to the New Drug Application (NDA) for simeprevir (TMC435), an investigational NS3/4A protease inhibitor administered as a 150 mg capsule once daily with pegylated interferon and ribavirin for the treatment of genotype 1 chronic hepatitis C in adult patients with compensated liver disease. Hepatitis...
Scientists show potential impact of therapy in reducing transmission in UK, Canada and Australia Around 150 million people globally are chronically infected with the hepatitis C virus (HCV) – a major cause of liver disease and the fastest growing cause of liver transplantation and liver cancer. 1 New prevention strategies are urgently required as people are continuing to be infected with HCV. Findings, published in Hepatology, reveal the impact of a new antiviral treatment that could...
New survey from hepatitiscnews.com finds that almost two thirds of people with hep C have experienced stigma and discrimination. (PRWEB) May 05, 2013 The survey, conducted by the online community hepatitisCnews.com, also found low awareness of the virus, and four out of ten respondents admitted that they had never heard of hepatitis C until they were diagnosed. While 87% told their family and friends about their diagnosis, over 70% said that people they told had a limited understanding of...
Benefits include improved drug efficiency, reduced pill burden, and lower dosage frequency LONDON, May 1, 2013 /PRNewswire/ -- The limited efficacy and negative side-effects associated with current therapeutics for Hepatitis B and C are highlighting the urgent need for new, improved alternatives. Combination therapies offering better clinical outcomes are coming to the fore and look set to transform the European market for Hepatitis B and C. New analysis from Frost & Sullivan...
A new survey by hepatitiscnews.com has found that almost two thirds of people living with hepatitis C have experienced discrimination and stigma in their daily lives due to their condition. (PRWEB) April 25, 2013 The survey, carried out by online community hepatitisCnews.com, also uncovered low awareness levels of the virus, with four out of ten respondents admitting that they had never heard of hepatitis C until their diagnosis. While 87% of those taking part in the survey shared their...
Exciting new data presented today at the International Liver Congress™ 2013 include results from early in vitro and in vivo studies targeting covalently closed circular DNA (cccDNA), which may form the basis of a cure for chronic hepatitis B virus (HBV) infection. HBV cccDNA is organized into mini-chromosomes within the nucleus of infected cells by histone and non-histone proteins. Despite the availability of efficient therapies against HBV, long-term persistence of cccDNA necessitates...
-- STARTVerso(TM)1 data presented in treatment-naïve patients with genotype-1 hepatitis C treated with investigational faldaprevir and pegylated interferon/ribavirin1,2 -- Statistically significant viral cure rates achieved versus placebo plus PegIFN/RBV with similar rates of treatment discontinuation -- The majority of patients qualified for shorter treatment duration of 12 weeks faldaprevir/24...
RIDGEFIELD, Conn., April 8, 2013 /PRNewswire/ -- Boehringer Ingelheim today announced that data from its pivotal STARTVerso(TM) 1 Phase 3 hepatitis C clinical trial have been accepted for oral presentation as a late-breaker at the International Liver Congress(TM) 2013: 48th Annual Meeting of the European Association for the Study of the Liver (EASL), taking place from April 24-28 in Amsterdam, The Netherlands. The STARTVerso(TM) 1 trial evaluated faldaprevir (BI 201335), an...
Latest Viral hepatitis Reference Libraries
Image Caption: This electron micrograph reveals the presence of hepatitis-B virus HBV "Dane particles", or virions. Credit: CDC/Wikipedia Hepatitis B: What Is It? Hepatitis simply means a swelling or inflammation of the liver. The type hepatitis that a person contracts (there are 5 common forms) affects their long-term prognosis. The most common and most severe of these different types of liver infection is Hepatitis B, which is caused by the hepatitis B virus (HBV). It is typically...
Hepatitis A, caused by hepatitis A virus, is an acute infectious disease of the liver that is transmitted person to person by ingestion of contaminated food or water or through direct contact with an infectious person. Millions of people are believed to become infected with HAV every year. The incubation period is two to six weeks and on average is 28 days. In less developed countries the HAV is usually contracted in early childhood. Clean water helps to decrease contraction of HAV. In 90%...
Hepatitis C virus (HCV) is an enveloped, positive-sense single-stranded RNA virus of the family Flaviviridae. It consists of a core of genetic material surrounded by an icosahedra protective shell of protein. The genome consists of a single open reading frame that is 9600 nucleotide bases long. HCV replication takes several steps. It primarily replicates in the hepatocytes of the liver. It can also reproduce in peripheral blood mononuclear cells. There is a wide variety of genotypes and...
Hepatitis B virus, HBV, is a part of the Hepadnaviridae family of viruses. HBV can lead to cirrhosis and hepatocellular carcinoma and has been linked to pancreatic cancer. It is classified as a species of the Orthohepadnavirus. Similar viruses have been found worldwide in great apes and monkeys. There a few different genotypes and they all differ by at least 8% of the sequence and have distinct geographical distributions and this has been associated with anthropological history. Type A is...
Hepadnaviruses can cause liver infections in humans and animals. The two recognized genera are Genus Orthohepadnavirus and Genus Avihepadnavirus. It has a small genome of partially double-stranded, partially single stranded circular DNA. It is a group 7 virus that uses an RNA intermediate during replication. Most people who come into contact with the virus are able to clear the infection alone although some cannot and usually progress to fulminant hepatitis. It can cause sever liver...
