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Latest Virulence Stories

2009-02-04 12:23:11

U.S. scientists say they have uncovered genetic clues about why some strains of the pathogen that causes Q fever are more virulent than others. Researchers from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center and the Virginia Bioinformatics Institute at Virginia Tech compared the sequences of four strains of Coxiella burnetii -- an intracellular bacterium that can cause acute and chronic Q fever in humans. Q fever is considered one of the most infectious...

2009-02-02 15:45:49

Scientists from the National Institute of Allergy and Infectious Diseases, Texas A&M Health Center, and the Virginia Bioinformatics Institute at Virginia Tech have uncovered genetic clues about why some strains of the pathogen Coxiella burnetii are more virulent than others.The researchers compared the sequences of four different strains of C. burnetii, an intracellular bacterium that can cause acute and chronic Q fever in humans, to build up a comprehensive picture of the genetic...

2009-01-27 13:31:37

Helicobacter pylori, a Gram-negative, flagellated, microaerophilic bacterium, can selectively colonize in the human stomach. Its infection is widespread throughout the world, and is present in about 50% of the global human population with 80% in developing countries and 20-50% in industrialized countries. Infection of the stomach with H. pylori induces a local immune response with infiltration of the mucosa by macrophages, neutrophils and lymphocytes. Although the innate and adaptive immune...

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2009-01-27 12:08:22

Biodesign Institute at Arizona State University associate research scientist Melha Mellata, a member of professor Roy Curtiss' team, is leading a USDA funded project to develop a vaccine against a leading poultry disease called avian pathogenic E. coli (APEC). APEC is part of a large, diverse group of microbes called extra-intestinal pathogenic E. coli (ExPEC). They cause a number of complex brain, lung and urinary tract diseases in human, animals, and birds. There is also considerable...

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2009-01-23 08:20:00

If you want to know how prehistoric people migrated, follow the "bugs" they carried with them. A consortium of scientists that included two from Baylor College of Medicine and the Michael E. DeBakey Veterans Affairs Medical Center in Houston did just that and in a report in the current issue of the journal Science, they described the two prehistoric migrations that populated the nations of the Pacific Ocean by looking at the travels of two different strains of a particularly nasty bacteria...

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2009-01-19 16:16:07

Scientists at The University of Nottingham are leading a major European study to unravel the genetic code of one of the most lethal strains of hospital acquired infections. The 3 million euro, three-year study will use gene knock-out technology developed in Nottingham to study the function of genes in a "Ëœsuper' strain of the bacteria Clostridium difficile to discover why it causes more severe disease, kills more people, is harder to eradicate and more resistant to antibiotics. It...

2008-12-12 10:25:36

Infectious pathogens like Salmonella typhimurium employ a startling array of techniques to skillfully outwit the body's defense mechanisms and produce illness. Through their expression of genes"”the fundamental building blocks of cellular physiology"”such microbes ingeniously adapt to varied environments, modifying their disease-causing potential or virulence.Although the study of a broad range of microbial virulence factors is now well advanced, many pieces of the puzzle are...

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2008-10-10 13:34:11

Scientists from the Universities of Bath and Exeter have developed a rapid new way of checking for toxic genes in disease-causing bacteria which infect insects and humans. Their findings could in the future lead to new vaccines and anti-bacterial drugs. They studied a bacterium called Photorhabdus asymbiotica, which normally infects and kills insects, but which can also cause an unpleasant infection in humans. By testing groups of genes from the bacteria against three types of invertebrates...

2008-07-18 06:00:22

Research and Markets (http://www.researchandmarkets.com/research/8cb5a3/evolution_in_healt) has announced the addition of the "Evolution in Health and Disease" report to their offering. A fully revised edition of a volume written by the worlds leading authorities on this subject. It discusses how the evolution of humans and their pathogens have generated important medical issues, covering both infectious and degenerative diseases. It presents important ideas that are not yet sufficiently...

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2008-07-16 10:48:09

Disease-causing microbes like the food-borne bacterium Listeria monocytogenes specialize in invading and replicating inside their animal hosts' own cells, making them particularly tricky to defeat. Now, a new study led by biologists at the University of California, Berkeley, has identified a molecular alarm system in which the intracellular pathogen sends out signals that kick the immune response into gear. The findings, to be reported the week of July 14 in the journal Proceedings of the...


Latest Virulence Reference Libraries

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2011-04-14 13:29:59

Acinetobacter baumannii is a species of pathogenic bacteria that is resistant to most antibiotics. Some think the disease is killing tens of thousands of U.S. hospital patients each year due to its resistance to drug treatment. It can cause severe pneumonia and infections of the urinary tract, bloodstream, and other parts of the body. It forms opportunistic infections including reports of attacking wounded soldiers and is sometimes abbreviated as MDRAB. It is the most relevant human...

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