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Latest Virulence Stories

2012-04-05 14:04:49

New treatments that combat the growing problem of antibiotic resistance by disarming rather than killing bacteria may be on the horizon, according to a new study. Published in Nature Structure and Molecular Biology, research led by Monash University showed a protein complex called the Translocation and Assembly Module (TAM), formed a type of molecular pump in bacteria. The TAM allows bacteria to shuttle key disease-causing molecules from inside the bacterial cell where they are made, to...

2012-04-02 11:08:30

Less resistance can sometimes be better than more--at least in a freshwater lake When battling a deadly parasite epidemic, less resistance can sometimes be better than more, a new study suggests. A freshwater zooplankton species known as Daphnia dentifera endures periodic epidemics of a virulent yeast parasite that can infect more than 60 percent of the Daphnia population. During these epidemics, the Daphnia population evolves quickly, balancing infection resistance and reproduction....

2012-03-29 23:15:36

When battling an epidemic of a deadly parasite, less resistance can sometimes be better than more, a new study suggests. A freshwater zooplankton species known as Daphnia dentifera endures periodic epidemics of a virulent yeast parasite that can infect more than 60 percent of the Daphnia population. During these epidemics, the Daphnia population evolves quickly, balancing infection resistance and reproduction. A new study led by Georgia Institute of Technology researchers reveals that...

2012-03-23 13:12:45

Researchers compare the genome of 2 parasites to explain differences in host range and transmission strategy Researchers have found the subtle genetic differences that make one parasite far more virulent than its close relative. They looked at the evolution of these parasites and found that although their genome architecture still remains similar, the two split from their common ancestor 28 million years ago, approximately four times longer than the human-gorilla split. Toxoplasma is...

2012-03-08 15:01:28

Scientists from the Schepens Eye Research Institute, a subsidiary of Mass. Eye and Ear and affiliate of Harvard Medical School, have found for the first time that a bacterial pathogen can literally mow down protective molecules, known as mucins, on mucus membranes to enter and infect a part of the body. Their landmark study, published in the March 7, 2012 PLoS ONE, describes how they discovered that an "epidemic" strain of the bacterium Streptococcus pneumoniae, which causes conjunctivitis,...

2012-02-27 11:28:39

How subverting the immune system shapes the arms race between bacteria and hosts Why is it that Mycobacterium tuberculosis can cause tuberculosis with as little as 10 cells, whereas Vibrio cholerae requires the host to ingest up to tens of millions of cells to cause cholera? This is the question that two research teams, from the Pasteur Institute, in France, and the Instituto Gulbenkian de Ciencia and the University of Lisbon, in Portugal, answer in the latest issue of the journal PLoS...

Nasty 'Superbug' Being Studied By Researchers
2012-02-18 06:00:55

It's virulent, potentially drug-resistant, strikes otherwise healthy, young patients, and Buffalo has already seen one case University at Buffalo researchers are expressing concern about a new, under-recognized, much more potent variant of a common bacterium that has surfaced in the U.S. "Historically, in Western countries, classical strains of Klebsiella pneumoniae have caused infections mostly in sick, hospitalized patients whose host defense systems are compromised," says Thomas...

2012-02-06 22:37:07

Susceptibility to anthrax toxin is a heritable genetic trait that may vary tremendously among individuals, according to a new study by researchers at the Stanford University School of Medicine. Among 234 people studied, the cells of three people were virtually insensitive to the toxin, while the cells of some people were hundreds of times more sensitive than those of others. The findings may have important implications for national security, as people known to be more resistant to anthrax...

2012-02-01 20:49:13

Studying self-replicating genetic units, called plasmids, found in one of the world's widest-ranging pathogenic soil bacteria -- the crown-gall-disease-causing microorganism Agrobacterium tumefaciens -- Indiana University biologists are showing how freeloading, mutant derivatives of these plasmids benefit while the virulent, disease-causing plasmids do the heavy-lifting of initiating infection in plant hosts. The research confirms that the ability of bacteria to cause disease comes at a...

2012-01-31 06:09:55

Among medical mysteries baffling many infectious disease experts is exactly how the deadly pneumonic plague bacterium, Yersinia pestis, goes undetected in the first few day of lung infection, often until it's too late for medical treatment. New research from the University of North Carolina at Chapel Hill School of Medicine has opened a door to the answer. Researchers led by William E. Goldman, PhD, professor and chair of microbiology and immunology at the University of North Carolina at...


Latest Virulence Reference Libraries

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2011-04-14 13:29:59

Acinetobacter baumannii is a species of pathogenic bacteria that is resistant to most antibiotics. Some think the disease is killing tens of thousands of U.S. hospital patients each year due to its resistance to drug treatment. It can cause severe pneumonia and infections of the urinary tract, bloodstream, and other parts of the body. It forms opportunistic infections including reports of attacking wounded soldiers and is sometimes abbreviated as MDRAB. It is the most relevant human...

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