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Latest Visual phototransduction Stories

2013-02-13 11:44:06

Research led by Minghao Jin, PhD, Assistant Professor of Ophthalmology and Neuroscience at the LSU Health Sciences Center New Orleans Neuroscience Center of Excellence, has found a protein that protects retinal photoreceptor cells from degeneration caused by light damage. This protein may provide a new therapeutic target for both an inherited retinal degenerative disease and age-related macular degeneration. The paper is published in the February 13, 2013 issue of the Journal of Neuroscience....

Improving The Skin's Response To UVA Light
2013-01-22 05:41:26

April Flowers for redOrbit.com - Your Universe Online A group of researchers from Brown University have demonstrated that certain skin cells use a light-sensitive receptor found outside of the eye to detect ultraviolet light and quickly begin producing melanin to prevent DNA damage. The same team, in a new study published in Proceedings of the National Academy of Sciences, has identified a key player in that biomolecular chain of events that could become a pharmacological target for...

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2011-03-05 11:16:08

'Out of the blue' discovery marks new direction in phototransduction studiesA UC Irvine research team led by Todd C. Holmes has discovered a second form of phototransduction light sensing in cells that is derived from vitamin B2. This discovery may reveal new information about cellular processes controlled by light.For more than 100 years, it had been believed that the phototransduction process was solely based on a chemical derived from vitamin A called retinal. Phototransduction is the...

2010-06-25 15:11:33

Retinitis pigmentosa affects over one million people worldwide and is manifested by a progressive loss of sight, eventually leading to blindness. Retinitis pigmentosa is a form of inherited retinal degeneration that affects the light-sensitive cells : photoreceptors. Photoreceptors are a special type of neuron which convert light into nervous impulses. These impulses are then processed by the retina and transmitted along the nerve fibres to the brain. There are two types of photoreceptors:...

2010-02-17 08:34:10

Research by Johns Hopkins sensory biologists studying fruit flies, has revealed a critical step in fly vision. Humans with problems in this same step suffer retinal dystrophies, which manifest as visual defects ranging from mild visual impairments to complete blindness. The article, published Jan. 26 in Current Biology paves the way for using the fruit fly to screen for therapies to treat human retinal degeneration. Retinal dystrophies result from inherited defects in nearly every step of the...

2009-10-13 15:11:30

Ever wonder how your eyes adjust during a blackout? When we go from light to near total darkness, cells in the retina must quickly adjust. Vision scientists at Washington University School of Medicine in St. Louis have identified an intricate process that allows the human eye to adapt to darkness very quickly. The same process also allows the eye to function in bright light. The discovery could contribute to better understanding of human diseases that affect the retina, including age-related...

2009-08-13 11:06:34

 One year after a trio of young adults received gene therapy for an inherited form of blindness, researchers have documented that the patients are still experiencing the same level of remarkable vision improvements previously measured within weeks. This is the first study to report one-year gene therapy safety and efficacy results in treating young adults with Leber Congenital Amaurosis (LCA), a hereditary condition that causes severe vision impairment in infants and children. The...

2009-08-13 09:47:18

Three young adults who received gene therapy for a blinding eye condition remained healthy and maintained previous visual gains one year later, according to an August online report in Human Gene Therapy. One patient also noticed a visual improvement that helped her perform daily tasks, which scientists describe in an Aug. 13 letter to the editor in the New England Journal of Medicine.These findings have emerged from a phase I clinical trial supported by the National Eye Institute (NEI) at the...

2008-10-09 09:00:52

VANCOUVER, Oct. 9 /PRNewswire-FirstCall/ -- QLT Inc. (NASDAQ: QLTI; TSX: QLT) announced today that it has initiated a Phase I safety study in healthy adults of QLT091001, an orally administered synthetic retinoid replacement therapy for 11-cis-retinal, which is a key biochemical component of the visual retinoid cycle. The drug is being developed for the potential treatment of Leber's Congenital Amourosis (LCA), an inherited progressive retinal degenerative disease that leads to retinal...

2005-08-11 19:30:00

In findings that could lead to curing some forms of congenital blindness through gene therapy, researchers at UCLA have discovered that RPE65, a gene missing in infants born with the blinding disease Leber congenital amaurosis, is also a key enzyme in the visual cycle. The identity of this enzyme has long been a mystery to scientists. The study, "Rpe65 is the Retinoid Isomerase in Bovine Retinal Pigment Epithelium," is published in the Aug. 12 issue of Cell magazine. "We were amazed when we...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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