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Latest Vivek Rangnekar Stories

2014-01-10 11:15:00

A new study led by University of Kentucky researchers suggests that activating the tumor suppressor p53 in normal cells causes them to secrete Par-4, another potent tumor suppressor protein that induces cell death in cancer cells. This finding may help researchers decipher how to inhibit the growth of tumors that have become resistant to other treatments. Loss of the tumor suppressor p53 often contributes to therapy resistance in tumors. In the study, published in Cell Reports, the...

Super Mouse Gene Cancer Treatment
2013-07-31 08:59:51

Alan McStravick for redOrbit.com - Your Universe Online The mouse as a model for genetic study has been a relationship our furry friends have served well in. The mouse is a convenient subject of study for its close mammalian similarities to we humans as well as for their short reproductive and growth cycles. Back in 2007, researchers at the University of Kentucky genetically manipulated one of these creatures to become a so-called "super mouse." And from this genetic strain of mouse have...

2011-08-25 03:36:19

Bone marrow transplantation with genetically modified cells may prolong the period of cancer-free survival, suggests a study led by Dr. Vivek Rangnekar, associate director of translational research for the Markey Cancer Center at the University of Kentucky. Bone marrow, a spongy tissue inside bones, contains stem cells that produce blood cells, including leukocytes, erythrocytes and platelets. In the cover story of the July issue of Cancer Biology & Therapy, Rangnekar and his team...

2009-07-23 13:55:00

Research builds on previous Par-4 study that produced cancer-resistant mouseHuman cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found.Researchers led by Vivek Rangnekar, UK professor of radiation medicine, have determined that the tumor-suppressor protein Par-4, initially thought to be active only within cells expressing the Par-4 gene, is in fact secreted by most human and rodent cells and can target large numbers of...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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