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Latest Voltage-dependent calcium channel Stories

2013-11-25 09:57:46

Filtered from a vast sodium sea, more than 1 million calcium ions per second gush through our cells' pores to generate charges Scientists have figured out how calcium channels – the infinitesimal cell membrane pores that generate electrical signals by gating a charged-particle influx – have solved a "needle in a haystack" problem. The solution to the longstanding riddle is reported in the Nov. 24 advanced online edition of Nature by University of Washington and Howard Hughes Medical...

2011-07-14 15:17:23

The human genome encodes 243 voltage-gated ion channels. Mutations in calcium channels can cause severe inherited diseases such as migraine, night blindness, autism spectrum disorders and Timothy syndrome, which leads to severe cardiovascular disorders. Katrin Depil and Anna Stary-Weinzinger together with colleagues from the Department of Pharmacology and Toxicology, University of Vienna analyzed changes in molecular organization of calcium channels caused by Timothy syndrome mutations....

2011-01-26 13:09:34

New finding adds significantly to our understanding of calcium channel function in health and disease Scientists in the Hotchkiss Brain Institute at the Faculty of Medicine, University of Calgary, have discovered a new mechanism that nerve cells (neurons) use to fine-tune their electrical output. The exciting discovery, published this week in the prestigious journal Nature Neuroscience, provides new insights about how the activity of the nervous system is regulated at the cellular level....

2009-10-26 14:26:00

NEW YORK, Oct. 26 /PRNewswire/ -- Reportlinker.com announces that a new market research report is available in its catalogue. Reportlinker Adds Ion Channel Modulator Pipelines: Targets and Agents in Development http://www.reportlinker.com/p0156556/Reportlinker-Adds-Ion-Channel-Modulator-Pipelines-Targets-and-Agents-in-Development.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=prnewswire Ion channels represent a significant opportunity to address an underexploited class of...

2009-10-19 08:27:16

Study shows PIKfyve protects neurons from calcium overload through degradation of calcium channels Tsuruta et al. find that a lipid kinase directs a voltage-gated calcium channel's degradation to save neurons from a lethal dose of overexcitement. The study appears in the October 19, 2009 issue of the Journal of Cell Biology. An important player in cellular signaling, calcium is also terribly toxic at high levels. Neurons have evolved ways to protect themselves against the calcium influxes...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.