Latest Von Hippel-Lindau tumor suppressor Stories

Randy Miller, company President, will open the doors to Northeast Data Destruction - their NAID “AAA” Certified processing facility to all residents and businesses for one day of document shredding. Plainville, MA (PRWEB) May 15, 2013 Northeast Data Destruction, a division of Miller Recycling Corporation, will be hosting their first paper shredding fundraiser event. Randy Miller, company President, will open the doors to Northeast Data Destruction - their NAID “AAA” Certified...

Randy Miller, Company President, will open the doors to Northeast Data Destruction - their NAID “AAA” Certified processing facility to the public for one day of document shredding. Plainville, Massachusetts 02762 (PRWEB) May 08, 2013 Northeast Data Destruction, a division of Miller Recycling Corporation, will be hosting their first document shredding fundraiser event. Randy Miller, Company President, will open the doors to Northeast Data Destruction - their NAID “AAA” Certified...

Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumors might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a new study to be presented at the 28th Annual EAU Congress currently on-going in Milan. "The inactivation of the von Hippel-Lindau gene (VHL) is a common event in ccRCC and finally leads to the induction of HIF1α target genes such as CA9 and VEGF," write the authors....

BOSTON, Nov. 1, 2012 /PRNewswire/ -- The von Hippel-Lindau Family Alliance (VHLFA), the leading resource for von Hippel-Lindau (VHL) and related tumor conditions, is pleased to honor Joyce W. Graff, Founding Executive Director of the VHL Family Alliance and William G. Kaelin, Jr, MD of Dana Farber Cancer Institute, Brigham and Women's Hospital, and Harvard School of Medicine. The Fundraising Dinner will take place on November 19(th) in Brookline, MA...

It seems as if a tumor deprived of oxygen would shrink. However, numerous studies have shown that tumor hypoxia, in which portions of the tumor have significantly low oxygen concentrations, is in fact linked with more aggressive tumor behavior and poorer prognosis. It’s as if rather than succumbing to gently hypoxic conditions, the lack of oxygen commonly created as a tumor outgrows its blood supply signals a tumor to grow and metastasize in search of new oxygen sources – for example,...

BOSTON, Aug. 20, 2012 /PRNewswire/ -- The von Hippel-Lindau Family Alliance (VHLFA), the leading resource for von Hippel-Lindau (VHL) and related tumor conditions, is pleased to announce the launch of its new, user-friendly website, http://www.vhl.org. The goal of the new site is to provide visitors with easily accessible information regarding research, treatment, and support. In upholding VHLFA's mission to improve diagnosis, treatment, and quality of life for individuals and...

In addition to the well-known risk factor of smoking, chronic obstructive pulmonary disease (COPD) increases lung cancer risk. A University of Colorado Cancer Center study published in the journal Cancer Prevention Research details one novel mechanism of this risk: long-term oxygen depletion stimulates signals that promote tumor growth. In addition, this early study – performed in animal models – shows that tumors fueled by these COPD-induced signals may be especially susceptible to...

A new family of proteins which regulate the human body’s ‘hypoxic response’ to low levels of oxygen has been discovered by scientists at Barts Cancer Institute at Queen Mary, University of London and The University of Nottingham. The discovery has been published in the international journal Nature Cell Biology. It marks a significant step towards understanding the complex processes involved in the hypoxic response which, when it malfunctions, can cause and affect the progress of many...

Study published online today in Nature Genetics BGI, the world's largest genomics organization, announced that a study on frequent mutation of genes encoding ubiquitin-mediated proteolysis pathway (UMPP) components in clear cell renal cell carcinoma (ccRCC) is published online today in Nature Genetics. In addition to BGI, co-leaders of the study included Peking University Shenzhen Hospital, Shenzhen Second People's Hospital, among others. The study reveals that alteration of UMPP may...

BOSTON, Nov. 22, 2011 /PRNewswire/ -- On Thursday, November 10, 2011, Grey's Anatomy character "Henry Burton" played by actor Scott Foley died from complications from von Hippel-Lindau (VHL). Foley's character introduced the rare genetic disease to mainstream media and now it is our task to continue educating the world about VHL and one day find a cure. VHL is a genetic disease which causes excessive growth of blood vessels which cause abnormal growth of tumorous tissues in multiple...