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Latest Wade Regehr Stories

2012-05-14 09:43:22

Research findings may lead to new drugs designed to improve communication between brain cells and effectively treat neurological disorders Scientists at Weill Cornell Medical College have discovered that the single protein -- alpha 2 delta -- exerts a spigot-like function, controlling the volume of neurotransmitters and other chemicals that flow between the synapses of brain neurons. The study, published online in Nature, shows how brain cells talk to each other through these signals,...

2010-11-18 14:26:51

Researchers at the Stanford University School of Medicine, applying a state-of-the-art imaging system to brain-tissue samples from mice, have been able to quickly and accurately locate and count the myriad connections between nerve cells in unprecedented detail, as well as to capture and catalog those connections' surprising variety. A typical healthy human brain contains about 200 billion nerve cells, or neurons, linked to one another via hundreds of trillions of tiny contacts called...

2010-11-03 00:23:04

NJIT Associate Professor Victor Matveev, PhD, in the department of mathematical sciences, was part of a research team that published "N-type Ca2+ channels carry the largest current: Implications for nanodomains and transmitter release," in Nature Neuroscience on Oct. 17, 2010. http://www.nature.com/neuro/journal/v13/n11/abs/nn.2657.html Leading the project, Elise Stanley, PhD, a senior scientist at the Toronto Western Research Institute, said that Matveev's mathematical modeling showed that...

2010-04-15 13:09:18

Cultured cells in microfluidic chambers enable systematic experiments at the synapse In order to be able to understand complex organs such as the brain or the nervous system, simplified model systems are required. A group of scientists led by the Frankfurt brain researcher Erin Schuman has successfully developed a novel method to grow cultured neurons in order to investigate basic mechanisms of memory. The researchers grew two separate populations of neurons in microfluidic platforms. These...

2009-12-28 16:43:06

The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta (AÃŽ²) plays an important role in early synaptic failure, but little has been understood about AÃŽ²'s effect on the plasticity of dendritic spines. These spines are short outgrowths of dendrites (extensions of neurons) that relay electrical impulses in the brain. A single neuron's dendrite...

2009-05-05 13:26:23

U.S. scientists say they are the first to find a form of synaptic memory in the olfactory bulb -- the part of the brain that processes the sense of smell. Case Western Reserve University Associate Professor Ben Strowbridge and doctoral student Yuan Gao noted that during the 1970s, scientists discovered synapses could change their strength following brief periods of activity. That process, called long-term potentiation, is the leading candidate to explain how we store information about...

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2008-06-19 12:14:11

UCLA cellular neuroscientists are providing new insights into the mechanisms that underlie long-term memory "” research with the potential to treat long-term memory disorders. "The more we know about how long-term memory is induced in the brain and how our memories are maintained in the brain, the more we are going to be able to treat long-term memory loss," said David Glanzman, UCLA professor of physiological science and neurobiology, whose new research appears June 19 in the early...

2005-11-01 14:50:00

AUSTIN, Texas--Neurons experience large-scale changes across their dendrites during learning, say neuroscientists at The University of Texas at Austin in a new study that highlights the important role that these cell regions may play in the processes of learning and memory. The research, published online Oct. 23 and in the November issue of the journal Nature Neuroscience, shows that ion channels distributed in the dendritic membrane change during a simulated learning task and that this...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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