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Latest Wee1 Stories

2010-03-11 09:07:54

Current drugs used to treat heart failure and arrhythmias (irregular heartbeat) have limited effectiveness and have side effects. New basic science findings from a University of Iowa study suggest a way that treatments could potentially be refined so that they work better and target only key heart-related mechanisms. The team, which included researchers from Vanderbilt University, showed in theory that it might be possible to use drugs that maintain the positive effects on heart function of a...

2009-10-20 08:15:00

When mother and daughter cells are created each time a cell divides, they are not exactly alike. They have the same set of genes, but differ in the way they regulate them. New research now reveals that these regulatory differences between mother and daughter cells are directly linked to how they prepare for their next split. The work, a collaboration between scientists at Rockefeller University and the State University of New York, Stony Brook, may ultimately lead to a better understanding of...

2009-06-16 07:39:18

Water is a crucial ingredient for life, but its level inside cells must be carefully regulated to maintain proper cell shape and size. In this week's issue of the open access journal PLoS Biology, scientists from the University of Gothenburg describe the highest resolution three-dimensional structure yet of a membrane protein, in this case of a protein channel known as an aquaporin that regulates water flow into and out of yeast cells. Virtually all living organisms use aquaporins to regulate...

2008-08-27 09:00:31

By Liu, Jingjing Zhang, Yiyue; Qin, Genji; Tsuge, Tomohiko; Sakaguchi, Norihiro; Luo, Guo; Sun, Kangtai; Shi, Dongqiao; Aki, Shiori; Zheng, Nuoyan; Aoyama, Takashi; Oka, Atsuhiro; Yang, Weicai; Umeda, Masaaki; Xie, Qi; Gu, Hongya; Qu, Li-Jia Following meiosis, plant gametophytes develop through two or three rounds of mitosis. Although the ontogeny of gametophyte development has been defined in Arabidopsis thaliana, the molecular mechanisms regulating mitotic cell cycle progression are not...

2005-07-18 05:47:48

Cells control mitosis (cell division) by assembling a biochemical switch to block it or by disassembling the switch to trigger it, according to investigators at St. Jude Children's Research Hospital and the Technical University of Munich. The researchers found that when the switch called SCFNIPA is intact, levels of an enzyme called cyclin B1 drop, preventing the enzyme from activating a third protein called Cdk1. By blocking the interaction between cyclin B1 and Cdk1, SCFNIPA prevents the...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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