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Latest Wellcome Trust Sanger Institute Stories

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2009-07-20 13:18:08

Researchers expose the biology of C. difficile transmission in mice New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of scientists have successfully mirrored the infection cycle of C. difficile by generating a 'mouse hospital' with conditions mimicking the human environment in which...

2009-07-15 12:45:00

Schistosome parasite genome reveals drug-sensitive candidatesResearchers have today published the complete genome sequence of the Schistosoma mansoni, a parasitic worm "“ commonly known as a blood fluke "“ that causes devastating disease. The World Health Organization ranks schistosomiasis as a neglected disease of the poor, affecting 210 million people in 76 countries, and each year causing 280,000 deaths in sub-Saharan Africa alone.The international team has identified several...

2009-07-13 08:37:00

LEXINGTON, Mass. and HEIDELBERG, Germany, July 13 /PRNewswire/ -- febit holding gmbh announced today the launch of the first human cancer biochip for HybSelect, febit's highly automated technology for sequence capture, enabling targeted Next-Generation Sequencing (NGS). The new catalog cancer biochip features 115 important genes which are reported to be associated with common types of cancer by the Wellcome Trust Sanger Institute. "Molecular signatures defined by large-scale gene...

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2009-05-25 14:20:54

An international research collaboration coordinated by UCD researchers and involving scientists at 21 institutes including the genome sequencing centers in the Wellcome Trust Sanger Institute, UK and the Broad Institute at MIT and Harvard, USA have defined six new genome sequences in the Candida fungus family and identified genetic differences in species that cause disease. The research, published yesterday in Nature, describes how Candida strains have evolved and ensured their survival by...

2009-04-20 14:08:29

An international team of more than 70 researchers says it has found nine new genes on the X chromosome that, when knocked-out, lead to learning disabilities. The scientists said they studied nearly all X chromosome genes in 208 families with learning disabilities. The researchers said they also discovered approximately 1 percent of X chromosome genes, when knocked-out, have no apparent effect on an individual's ability to function in the ordinary world. Estimates suggest the prevalence of...

2009-04-19 13:17:17

A collaboration between more than 70 researchers across the globe has uncovered nine new genes on the X chromosome that, when knocked-out, lead to learning disabilities. The international team studied almost all X chromosome genes in 208 families with learning disabilities - the largest screen of this type ever reported.Remarkably, the team also found that approximately 1ð”Æ’% of X chromosome genes, when knocked-out, have no apparent effect on an individual's...

2009-04-16 09:55:21

Database provides a key to unlock the causes of illnesses Today - five years after the inception of the DECIPHER database - researchers have published a report that reveals the developing role of the database in revolutionizing both clinical practice and genetic research. The report explores the growing benefits of DECIPHER for researchers, clinicians and patients - highlighting how the data, provided by around 100 centers and shared openly worldwide, can benefit all three groups. DECIPHER -...

2009-04-14 12:22:07

Parallel studies in mice and humans by Spanish and British scientists have found a new kind of genes -- micro RNAs -- are linked to progressive hearing loss. The researchers said their findings provide important new genetic understanding of a condition that's common in humans yet remains poorly understood. The Spanish scientists from the Hospital Ramon Cajal in Madrid followed families who showed hearing loss. The second team, led by British researchers from the Wellcome Trust Sanger...

2009-04-13 07:48:42

Human and mouse share hearing deficit caused by mutation in microRNA In parallel studies in human and mouse, two groups of researchers have come to the same conclusion: that a new kind of gene is associated with progressive hearing loss. The new gene - called a microRNA - is a tiny fragment of RNA that affects the production of hundreds of other molecules within sensory hair cells of the inner ear. The research provides important new genetic understanding of a condition that is common in...

2009-03-31 09:07:58

A team of British, Chinese and U.S. researchers has identified a new cancer gene called UTX, on the X chromosome. The scientists said the gene is found in 10 percent of multiple myeloma cases and in 8 percent of esophageal cancers. The researchers said UTX plays a role in overall regulation of the activity of many genes and it's possible they might find other genes with similar roles involved in different tumor types. The scientists said their finding is the first example of mutations in a...


Word of the Day
conjunto
  • A style of popular dance music originating along the border between Texas and Mexico, characterized by the use of accordion, drums, and 12-string bass guitar and traditionally based on polka, waltz, and bolero rhythms.
The word 'conjunto' comes through Spanish, from Latin coniūnctus, past participle of coniungere, to join together; see conjoin