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Latest Wellcome Trust Sanger Institute Stories

Zebrafish Genome Could Have Significant Implications For Human Health
2013-04-18 09:59:16

April Flowers for redOrbit.com - Your Universe Online Two new studies from the Wellcome Trust Sanger Institute involving the genome of zebrafish have been published in the journal Nature this week, giving insight into the relationship between humans, zebrafish and genetic mutations. FAMILY TIES According to the first study, 70 percent of protein-coding human genes are related to zebrafish genes, and 84 percent of the genes known to be associated with human disease have a counterpart...

2013-04-18 00:20:05

An international team of researchers join forces to decode the genome of the once-thought-to-be-extinct African coelacanthSingapore, Apr 18, 2013 - (ACN Newswire) - An enigmatic prehistoric fish has brought scientists at A*STAR's Institute of Molecular and Cell Biology (IMCB) together with researchers from all over the world to crack its genomic code. Findings from the study are providing new insights into the evolutionary history of the African coelacanth (Figure 1)(1) and possible clues as...

2012-12-11 21:34:13

New method to directly sequence small genomes without library preparation For the first time, researchers sequenced DNA molecules without the need for the standard pre-sequencing workflow known as library preparation. Using this approach, the researchers generated sequence data using considerably less DNA than is required using standard methods, even down to less than one nanogram of DNA; 500 times less DNA than is needed by standard practices. Libraries are collections of DNA...

2012-12-10 17:03:48

Researchers track the emergence and global spread of healthcare associated Clostridium difficile Researchers show that the global epidemic of Clostridium difficile 027/NAP1/BI in the early to mid-2000s was caused by the spread of two different but highly related strains of the bacterium rather than one as was previously thought. The spread and persistence of both epidemics were driven by the acquisition of resistance to a frontline antibiotic. Unlike many other healthcare-associated...

Nobody Is Perfect: Study Shows People Have 400 Genetic Flaws In DNA
2012-12-07 12:45:35

Lawrence LeBlond for redOrbit.com - Your Universe Online Perfection is something that all humans strive for at one time or another, be it scoring a perfect 100 on a test, making the perfect soufflé, having the perfect play in basketball, or even landing the perfect job. For others, perfection is a state of well-being–as in being perfectly healthy. While achieving perfect health may be plausible in sense of how one feels, new research shows that, at the genetic level,...

2012-12-01 05:01:42

International Experts in Computational Drug Design, Genome Interpretation, and an All-Star CIO Panel Headline 2013 Bio-IT Conference in Boston Needham, Mass. (PRWEB) November 30, 2012 Bio-IT World, part of the Cambridge Healthtech Institute (CHI), is proud to announce a pair of renowned keynote speakers and an exciting panel of life science CIOs among the upcoming attractions at its 2013 Conference & Expo, to be held in Boston next Spring (April 9-11, 2013). The keynote speakers will be...

2012-10-16 07:27:23

Collaborative research funded by the Chordoma Foundation yields major discovery that could open door to new therapies DURHAM, N.C., Oct. 16, 2012 /PRNewswire-USNewswire/ -- A genetic variation possessed by 40% of the population is associated with a five-fold increase in risk for developing chordoma, a cancer that strikes the bones of the skull and spine. A team of scientists at University College London (UCL), Royal National Orthopaedic Hospital (RNOH), and the Wellcome Trust Sanger...

2012-10-01 16:22:40

Researchers track the spread of human invasive non-Typhoidal Salmonella in sub-Saharan Africa A new study out today (Sunday 30 September) reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan Africa, seems to have been potentiated by the HIV epidemic in Africa. The team found that invasive non-Typhoidal Salmonella (iNTS) disease is caused by a new form of the bacteria...

2012-08-04 01:15:14

100 gene deletions in mice identifies 9 new genes that determine bone strength A genetic screening approach to studying bone disease has found nine new genes associated with bone health and suggests a new way to discover genes that may be implicated in human skeletal diseases. A collaborative study of the mineral content, strength and flexibility of bones has found clues to the cause of bone disorders such as osteoporosis, osteogenesis imperfecta, and high bone density syndromes. The...

2012-07-26 01:17:16

A University of Sheffield academic is helping a team of citizen scientists to carry out crucial research into European genetic heritage. Citizen Scientists are not required to have a scientific background or training, but instead they possess a passion for the subject and are increasingly being empowered by the scientific community to get involved in research. Dr Andy Grierson, from the University of Sheffield´s Institute for Translational Neuroscience (SITraN), has helped a team...