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Latest Wellcome Trust Sanger Institute Stories

2012-10-01 16:22:40

Researchers track the spread of human invasive non-Typhoidal Salmonella in sub-Saharan Africa A new study out today (Sunday 30 September) reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan Africa, seems to have been potentiated by the HIV epidemic in Africa. The team found that invasive non-Typhoidal Salmonella (iNTS) disease is caused by a new form of the bacteria...

2012-08-04 01:15:14

100 gene deletions in mice identifies 9 new genes that determine bone strength A genetic screening approach to studying bone disease has found nine new genes associated with bone health and suggests a new way to discover genes that may be implicated in human skeletal diseases. A collaborative study of the mineral content, strength and flexibility of bones has found clues to the cause of bone disorders such as osteoporosis, osteogenesis imperfecta, and high bone density syndromes. The...

2012-07-26 01:17:16

A University of Sheffield academic is helping a team of citizen scientists to carry out crucial research into European genetic heritage. Citizen Scientists are not required to have a scientific background or training, but instead they possess a passion for the subject and are increasingly being empowered by the scientific community to get involved in research. Dr Andy Grierson, from the University of Sheffield´s Institute for Translational Neuroscience (SITraN), has helped a team...

2012-07-20 00:15:00

Genome research for the health of the poorest of the poor Belgian scientists of the Institute of Tropical Medicine (ITM) in Antwerp, Belgium made a breakthrough in bridging high tech molecular biology research on microbial pathogens and the needs of the poorest of the poor. After sequencing the complete genome of Leishmania donovani (a parasite causing one of the most important tropical diseases after malaria) in hundreds of clinical isolates, they identified a series of mutations specific...

Ethiopian Genetics Could Verify 'Queen of Sheba' Legend
2012-06-22 08:04:57

UK researchers studying the genomes of Ethiopian people have discovered similarities to those of populations in Israel and Syria, proving genetic evidence that may support the tale of the legendary Queen of Sheba. Ethiopians are described by representatives of the Wellcome Trust Sanger Institute, one of the organizations involved in the study, as one of the most genetically diverse cultures in the world. By studying their DNA, the researchers detected mixing from some Ethiopians and...

2012-06-21 21:04:28

Diversity within Ethiopian genomes reveals imprints of historical events Researchers have started to unveil the genetic heritage of Ethiopian populations, who are among the most diverse in the world, and lie at the gateway from Africa. They found that the genomes of some Ethiopian populations bear striking similarities to those of populations in Israel and Syria, a potential genetic legacy of the Queen of Sheba and her companions. The team detected mixing between some Ethiopians and...

2012-05-16 22:52:06

Landscape of cancer genes and mutational processes in breast cancer In a study published today in Nature, researchers describe nine new genes that drive the development of breast cancer. This takes the tally of all genes associated with breast cancer development to 40. The team examined all the genes in the genomes of 100 cases of breast cancer. The mutated cancer-causing genes were different in different cancer samples, indicating that breast cancer is genetically very diverse....

2012-05-09 05:29:39

(Ivanhoe Newswire) —Last year it killed an estimated 655,000 people. Now researchers are developing new ways to block the transmission of Plasmodium, the parasite responsible for human malaria. Experts say the research could represent a new strategy for controlling the spread of infection. According to the World Health Organization, more than 200 million people contract malaria each year. Experts say in order to combat the deadly disease, new tools have to be developed to prevent new...

2012-03-29 02:27:15

Researchers identify genetic markers of drug sensitivity in cancer cells In the largest study of its kind, researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. The team uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs. One of the key responses the team found was that cells from a childhood bone cancer, Ewing's sarcoma, respond to a drug that is...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'