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Latest Wellcome Trust Sanger Institute Stories

Gene Can Transform Mild Flu Into A Life-threatening Disease
2012-03-26 07:13:43

An international team of researchers has discovered a human genetic flaw that could explain why influenza makes some people more sick than others. Reporting in the journal Nature, British and American researchers, led by the Wellcome Trust Sanger Institute (WTSI) in the UK, said the variant of the IFITM3 gene was much more common in people hospitalized for the flu than in those who were able to fight the disease at home. The researchers said this could explain why during the 2009/10...

2012-03-23 13:12:45

Researchers compare the genome of 2 parasites to explain differences in host range and transmission strategy Researchers have found the subtle genetic differences that make one parasite far more virulent than its close relative. They looked at the evolution of these parasites and found that although their genome architecture still remains similar, the two split from their common ancestor 28 million years ago, approximately four times longer than the human-gorilla split. Toxoplasma is...

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2012-03-13 07:56:05

A recent study posted in Nature Genetics explains that researchers have found that Chlamydia has been evolving differently than previously thought. The researchers used whole genome sequencing to find these results. Their findings show the exchange of DNA between different strains of the STD to form new strains is more common than expected. The researchers came about their findings while working with hospitals to improve their testing and detection of Chlamydia, particularly different...

2012-03-12 09:57:18

Whole genome analysis of Chlamydia trachomatis highlights risks with current method of tracking In a study released today in Nature Genetics, researchers have found that Chlamydia has evolved more actively than was previously thought. Using whole genome sequencing the researchers show that the exchange of DNA between different strains of Chlamydia to form new strains is much more common than expected. The team highlights that current clinical testing methods do not capture the variation...

Genome Reveals Humans, Gorillas More Alike Than Previously Thought
2012-03-08 07:53:30

Researchers who have completed the genome sequence of the gorilla have discovered that the species is more genetically similar to humans than they had previously thought. The study, which was led by researchers at the UK's Wellcome Trust Sanger Institute and the Baylor College of Medicine (BCM), looked at DNA from a 30-year-old female western lowland gorilla from the San Diego Zoo named Kamilah, Dave Mosher of National Geographic News reported on Wednesday. They began studying the...

Devil's Contagious Cancer Genome Sequenced
2012-02-17 05:48:15

[ Watch the Video ] The Tasmanian devil population is threatened to extinction with a highly contagious cancer. In order to understand the origins of the cancer, researchers have sequenced the complete genome of the cell and traced it back to what they are calling an ℠immortal´ female. Researchers hope by sequencing the genome they can find a way to help the Tasmanian devil. According to Elizabeth Murchison, a Tasmanian native working at the Wellcome Trust Sanger Institute in...

2012-02-17 00:31:25

Researchers develop a new catalogue to help identify gene variations associated with disease A high-quality reference catalogue of the genetic changes that result in the deactivation of human genes has been developed by a team of researchers. This catalogue of loss-of-function (LoF) variants is needed to find new disease-causing mutations and will help us to better understand the normal function of human genes. In addition, the researchers report that each of us is carrying around 20 genes...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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