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Latest Wellcome Trust Sanger Institute Stories

2011-12-20 18:10:38

A new candidate malaria vaccine with the potential to neutralize all strains of the most deadly species of malaria parasite has been developed by a team led by scientists at the University of Oxford. The results of this new vaccine independently confirm the utility of a key discovery reported last month from scientists at the Wellcome Trust Sanger Institute who had identified this target within the parasite as a potential 'Achilles' heel' that could hold significant promise for vaccine...

2011-12-14 11:49:04

Jamb and Jamc are essential proteins for the fusion of muscle cells Researchers at the Wellcome Trust Sanger Institute have discovered two proteins that are essential for the fusion of muscle cells to build muscle fibers. Their discovery might help us better understand and treat illnesses such as muscle-wasting disorders and diseases of bone over-growth, in which cellular fusion is an important feature. Cellular fusion is necessary to form larger cells that have specific functions...

Malaria Parasite Discovery May Lead To Vaccine
2011-11-10 14:08:10

[ Watch the Video ] Researchers have revealed a new discovery in understanding how a malaria parasite invades human red blood cells. The team from the Wellcome Trust Sanger Institute said they found that the parasite relies on a single receptor on the red blood cell's surface to invade. Malaria kills about a million people every year, most of them being children in Africa under the age of five. The blood stage of the parasite's lifecycle starts when it invades human red blood...

2011-11-07 11:45:51

A jumping gene named Sleeping Beauty plays vital role in investigating cancer pathway A jumping gene with the fairy tale name "Sleeping Beauty" has helped to unlock vital clues for researchers investigating the genetics of colorectal cancer. A study published today used the Sleeping Beauty transposon system to profile the repertoire of genes that can drive colorectal cancer, identifying many more than previously thought. Around one third of these genes are mutated in human cancer, which...

2011-10-28 12:11:35

Parasite genomes speak of evolution by changes in gene, region and chromosome number, not by mutation in genes Two remarkable discoveries were today revealed by researchers into genome analysis of Leishmania parasites. These results uncovered a surprising level of variation at the genome structure level. First, they found that the DNA sequence of individual strains of each species populations is almost completely identical. It appears that only a small number of genes may cause...

2011-10-12 23:11:52

New gene therapy methods accurately correct mutation in patient's stem cells, bringing personalized cell therapies one step closer For the first time, scientists have cleanly corrected a human gene mutation in a patient's stem cells. The result, reported in Nature on Wednesday 12 October, brings the possibility of patient-specific therapies closer to becoming a reality. The team, led by researchers from the Wellcome Trust Sanger Institute and the University of Cambridge, targeted a gene...

Culling Won’t Help Tasmanian Devil Populations
2011-10-05 08:45:59

Populations of Tasmanian devils in parts of Australia are suffering from Devil Facial Tumor Disease (DFTD) that has wiped out more than 90 percent of individual animals in some areas. Because of this, the animals have been the subject of a culling, or a purposeful killing of a large number of the animals, with hopes of removing the cancer from the general population. Conservation biologists began the cull in 2004. However a study in the Journal of Applied Ecology confirms that the...

2011-09-27 13:20:42

New genetic insights could facilitate screening for mutation A genomic study of chronic blood cancer - a precursor to leukaemia - has discovered gene mutations that could enable diagnosis using only a blood test, avoiding the need for an invasive and painful bone marrow biopsy. Researchers at the Wellcome Trust Sanger Institute identified the SF3B1 gene as being frequently mutated in myelodysplasia, one of the most common forms of blood cancer. Myelodysplasia is particularly prevalent...

Researchers Sequence DNA Of 17 Common Types Of Lab Mice
2011-09-16 09:53:31

  An international team of researchers have sequenced the genomes of 17 different strains of mice in what the National Science Foundation (NSF) is calling "an achievement that lays the groundwork for the identification of genes responsible for“¦ diseases that afflict both mice and humans." The work, which was spearheaded by researchers at the Wellcome Trust Sanger Institute and the University of Oxford, gives researchers the genetic blueprints of multiple varieties of...


Word of the Day
toccata
  • In music, a work for a keyboard-instrument, like the pianoforte or organ, originally intended to utilize and display varieties of touch: but the term has been extended so as to include many irregular works, similar to the prelude, the fantasia, and the improvisation.
This word is Italian in origin, coming from the feminine past participle of 'toccare,' to touch.
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