Latest Wellcome Trust Sanger Institute Stories

2009-11-02 07:40:00

A global collaborative has produced a first draft of the genome of a domesticated pig, an achievement that will lead to insights in agriculture, medicine, conservation and evolution. A red-haired Duroc pig from a farm at the University of Illinois will now be among the growing list of domesticated animals that have had their genomes sequenced. Researchers will announce the achievement Monday (Nov. 2) at a meeting at the Wellcome Trust Sanger Institute in Hinxton, England. "The pig is a unique...

2009-10-22 12:32:21

LANL among organizations proposing new genome sequence strategies A team of geneticists at Los Alamos National Laboratory, together with a consortium of international researchers, has recently proposed a set of standards designed to elucidate the quality of publicly available genetic sequencing information. The new standards could eventually allow genetic researchers to develop vaccines more efficiently or help public health or security personnel more quickly respond to potential...

2009-10-16 11:01:48

First high-throughput analysis of every Salmonella Typhi gene For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armories. Using a newly developed, next-gen sequencing method, a team established which genes Salmonella Typhi needs to survive and which are more of a luxury. The results and the method will be a boon to scientists...

2009-10-12 07:42:37

Genome-wide meta-analysis identifies 22 regions associated with blood cell traits A new genome-wide association study published Oct. 11 in Nature Genetics begins to uncover the basis of genetic variations in eight blood measurements and the impact those variants can have on common human diseases. Blood measurements, including the number and volume of cells in the blood, are routinely used to diagnose a wide range of disorders, including anemia, infection and blood cell cancers. An...

2009-10-09 10:57:22

In 1996, researchers from major genome sequencing centers around the world convened on the island of Bermuda and defined a finished genome as a gapless sequence with a nucleotide error rate of one or less in 10,000 bases. This effectively set the quality target for the human genome effort and was quickly applied to other genome projects. If a genome sequence didn't meet this stringent criterion, it was simply considered a "draft." More than a decade later, researchers are finding that with...

2009-10-08 09:47:46

New map of copy number variation in the human genome is a resource for human genetics In research published Oct. 7 by Nature, an international team describes the finest map of changes to the structure of human genomes and a resource they have developed for researchers worldwide to look at the role of these changes in human disease. They also identify 75 'jumping genes' - regions of our genome that can be found in more than one location in some individuals. However, the team cautions that they...

2009-10-07 15:50:00

An international research team has issued the most updated map of changes to the structure of human genomes. Writing in the journal Nature, researchers said the new map should provide others with a better approach to fighting human diseases. Researchers also reported the identification of 75 so-called "jumping genes," which are defined as regions of human genomes that can be found in more than one location. They used data compiled through scanning and comparing genomes of 450 people of...

2009-07-20 13:18:08

Researchers expose the biology of C. difficile transmission in mice New research suggests that antibiotic treatment could be asymptomatically inducing the transmission of the healthcare-acquired infection, C. difficile, contributing to the outbreaks that have recently been widely reported in hospitals and other settings. A team of scientists have successfully mirrored the infection cycle of C. difficile by generating a 'mouse hospital' with conditions mimicking the human environment in which...

2009-07-15 12:45:00

Schistosome parasite genome reveals drug-sensitive candidatesResearchers have today published the complete genome sequence of the Schistosoma mansoni, a parasitic worm "“ commonly known as a blood fluke "“ that causes devastating disease. The World Health Organization ranks schistosomiasis as a neglected disease of the poor, affecting 210 million people in 76 countries, and each year causing 280,000 deaths in sub-Saharan Africa alone.The international team has identified several...

2009-07-13 08:37:00

LEXINGTON, Mass. and HEIDELBERG, Germany, July 13 /PRNewswire/ -- febit holding gmbh announced today the launch of the first human cancer biochip for HybSelect, febit's highly automated technology for sequence capture, enabling targeted Next-Generation Sequencing (NGS). The new catalog cancer biochip features 115 important genes which are reported to be associated with common types of cancer by the Wellcome Trust Sanger Institute. "Molecular signatures defined by large-scale gene...

Word of the Day
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'