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Latest White blood cell Stories

Immune Cell DNA Used In Diagnostic Technique
2012-07-09 17:16:37

By looking at signature chemical differences in the DNA of various immune cells called leukocytes, scientists have developed a way to determine their relative abundance in blood samples. The relative abundance turns out to correlate with specific cancers and other diseases, making the technique, described in two recent papers, potentially valuable not only for research but also for diagnostics and treatment monitoring. When a person is sick, there is a tell-tale sign in their blood: a...

2012-07-05 10:24:19

Scientists at the University of East Anglia (UEA) have discovered a 'constant cloud' of potent inflammatory molecules surrounding the cells responsible for diseases such as thickening of the arteries and rheumatoid arthritis. Published online today by The Journal of Cell Science, the findings could eventually lead to new treatments for chronic inflammatory diseases. Cardiovascular disease arising from atherosclerosis (thickening of the arteries) kills around 17 million people worldwide...

2012-07-02 21:34:23

Novel mechanism plays major role in inflammation Like detectives seeking footprints and other clues on a television "whodunit," science can also benefit from analyzing the tracks of important players in the body's molecular landscape. Klaus Ley, M.D., a scientist at the La Jolla Institute for Allergy & Immunology, has done just that and illuminated a key step in the journey of inflammation-producing immune cells. The finding provides powerful, previously unknown information about...

Macrocure’s CureXcell Targets Hard-To-Heal Wounds
2012-06-21 08:53:18

Connie K. Ho for redOrbit.com Chronic wounds are a growing issue. Luckily, Macrocure´s CureXcell addresses that issue. Macrocure, a biotechnology company that specializes in cell therapy for hard-to-heal wounds, is currently conducting a multi center Phase III study in North America and Israel under a Special Protocol Assessment for lower extremity chronic ulcers for adults with diabetes. Macrocure´s lead product is CureXCell, an approach to treating hard-to-heal wounds by...

2012-05-03 19:04:58

A new study helps to resolve an ongoing controversy about whether Langerhans cells (LCs) in human skin function to suppress the immune response and promote tolerance to normal human skin and its "friendly" microbial flora or mobilize a lethal attack against harmful foreign invaders. The research, published online May 3rd in the journal Immunity by Cell Press, reveals that, depending on the situation, these versatile immune cells can perform either function. Adult human skin contains...

2012-05-02 20:14:36

Macrophages play a key role in the immune response, protecting organisms against infection and regulating the development of inflammation in tissue. Macrophages differ depending on where they are located and which tasks they perform. A scientist at TUM has been investigating whether these different types of cells have the same origin — and has come up with some surprising results. His findings reveal that there are two distinct macrophage cell lines that continue into adult life and...

2012-05-02 19:57:57

Margination, the natural phenomenon where bacteria and leukocytes (white blood cells) move toward the sides of blood vessels, is the inspiration for a novel method for treating sepsis, a systemic and often dangerous inflammatory response to microbial infection in the blood. A team of researchers at the Massachusetts Institute of Technology and the National University of Singapore has designed a branchlike system of microfluidic channels, 20 micrometers (20 millionths of a meter, or about...

2012-04-26 22:31:28

Listeria, one of the most deadly causes of bacterial food poisoning, subverts a normally protective immune response to spread its infection more effectively, according to new research at National Jewish Health. Immunologists Laurel Lenz, PhD, Peter Henson, PhD, and their colleagues report online April 26, 2012, in the journal Immunity that production of nitric oxide (NO) by activated macrophages, which is normally thought of as an infection-fighting response, actually helps Listeria...

2012-04-25 11:43:34

BBSRC-funded researchers at Cambridge University have shed new light on a common food poisoning bug. Using real-time video microscopy, coupled with mathematical modeling, they have changed our assumptions about Salmonella and how it infects human cells. The research was published in Interface. Salmonella is an important bacterium to study as it causes a range of diseases in humans and animals. It is capable of growing and reproducing inside macrophages - a type of white blood cell that...

2012-04-02 20:41:17

The characterisation of a rare immune cell´s involvement in antibody production and ability to ℠remember´ infectious agents could help to improve vaccination and lead to new treatments for immune disorders, say researchers from the Walter and Eliza Hall Institute. The cells, called T follicular helper cells, represent less than half of one per cent of all immune cells, but play a critical role in antibody production and developing long-lasting immunity. However, the cells...