Latest X-inactivation Stories
In previous research, UC Berkeley scientists Beatriz Vicoso, Ph.D., and Doris Bachtrog, Ph.D., determined that genes on the so-called "dot chromosome," or fourth chromosome, of the fruit fly Drosophilia melanogaster are X-linked in three other related fly species.
Calico cats are renowned and beloved for their funky orange and black patchwork or "tortoiseshell" fur. New research from the University of California San Francisco (UCSF), has further linked this unique color pattern to X chromosome inactivation or "silencing."
The first evidence that the underlying genetic defect responsible for trisomy 21, also known as Down syndrome, can be suppressed in laboratory cultures of patient-derived stem cells was presented today (Oct. 22) at the American Society of Human Genetics 2013 annual meeting in Boston.
Two new studies offer insight into sex chromosome evolution by focusing on papaya, a multimillion dollar crop plant with a sexual problem (as far as growers are concerned) and a complicated past.
A team led by scientists at The Scripps Research Institute and the University of California (UC) San Diego has discovered a new type of dynamic change in human stem cells.
Established human embryonic cell lines, including those approved for federal research funding under former President George W. Bush, are different than newly derived human embryonic stem cell lines.
Female induced pluripotent stem (iPS) cells, reprogrammed from human skin cells into cells that have the embryonic-like potential to become any cell in the body, retain an inactive X chromosome, stem cell researchers at UCLA have found.
Oxygen levels in the lab can permanently alter human embryonic stem (ES) cells, specifically inducing X chromosome inactivation in female cells, according to Whitehead Institute researchers.
Male mice born with female sex chromosomes experience hypertension seen in postmenopausal women
Because females carry two copies of the X chromosome to malesâ€™ one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome.