Latest X-inactivation Stories

2009-06-29 08:57:19

Dutch researchers have found the first evidence that a process of inactivating the X chromosome during embryo development and implantation, which was known to occur in mice but unknown in humans, does, in fact, take place in human female embryos prior to implantation in the womb.Ms Ilse van den Berg told the 25th annual meeting of the European Society of Human Reproduction and Embryology in Amsterdam today (Monday) that her findings may have implications for the laboratory cultures that...

2009-04-10 08:00:00

University of Nevada School of Medicine researcher leads important discoveryUniversity of Nevada School of Medicine scientists in the Department of Physiology and Cell Biology have discovered insight into the reproductive workings of the male sex chromosome that may have significant implications for male infertility and contraception.This important discovery has been published in Nature Genetics, one of the highest-ranking journals in the field of biomedical research based upon the impact...

2008-12-29 09:30:18

A research group lead by scientists at the University of Warwick has discovered the trigger that pulls together X chromosomes in female cells at a crucial stage of embryo development. Their discovery could also provide new insights into how other similar chromosomes spontaneously recognize each other and are bound together at key parts of analogous cell processes. This is an important mechanism as the binding togetgher of too many of too few of a particular chromosome can cause a number of...

2008-05-29 16:00:39

An enzyme that binds differently to male and female sex chromosomes helps males to make up for their X chromosome shortage Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI) in Hinxton, UK, have revealed new insights into how sex chromosomes are regulated. A chromatin modifying enzyme helps compensate for the fact that males have only one copy of the sex chromosome X, while females have two. The...

2005-09-30 16:55:57

Independent research papers from Dr. Peter Becker (Munich, Germany) and Dr. Mitzi Kuroda (Boston, MA) in the October 1 issue of Genes & Development delineate the mechanism of X-chromosome dosage compensation in Drosophila. In Drosophila, like in humans, male cells have a single X chromosome, while female cells have two. Researchers have long debated over how X and autosomal chromosome gene expression is equalized between the sexes (generally regarding two different models, known as the...

2005-03-16 13:45:56

Women get more work out of hundreds of genes on the X chromosome than men do, and that could help explain biological differences between the sexes, a new study says. The results imply that women make higher doses of certain proteins than men do, which could play out in gender differences in both normal life and disease, researchers said. So far, however, none of the genes identified in the study has been linked to any such observable differences, said senior study author Huntington Willard...

Word of the Day
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.