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Latest Xenotransplantation Stories

2013-11-25 15:07:15

Inhibition of the complement system protects the transplant of pig cartilage cells Researchers at the Bellvitge Institute of Biomedical Research (IDIBELL) led by Cristina Costa from the New Therapies on Genes and Transplantation group have shown that inhibition of one of the basic components of the complement system protects chondrocytes (cartilage cells) from porcine rejection of xenotransplantation (transplantation between animals of different species). Complement system The...

Animal-Human Transplants Work For Diabetes Treatment
2013-07-13 06:31:46

April Flowers for redOrbit.com - Your Universe Online Northwestern Medicine researchers have completed the first step toward animal-human transplants of insulin-producing cells for people with type-1 diabetes by successfully transplanting islets from one species to another. Islets are the cells that produce insulin. The findings of this study, published online in the journal Diabetes, show the islets survived without immunosuppressive drugs. The research team has developed a new method...

Pig Organs Could Be Transplanted Into Humans Within 2 Years
2011-10-21 10:59:02

Scientists said that organs grown in genetically modified pigs could be transplanted into humans in as soon as two years. Pittsburgh University scientists say that a trial transplanting pig corneas into humans with eye problems could begin as early as 2013. "With new genetically modified pigs becoming available that are likely to improve the outcome of cellular and corneal xenotransplantation further, we believe that clinical trials will be justified within the next two to three years,"...

2011-07-21 06:00:00

RICHMOND, Calif., July 21, 2011 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced the publication of a study demonstrating the use of zinc finger nucleases (ZFNs) to produce genetically modified pigs. The study, which was published in the Proceedings of the National Academy of Sciences (PNAS), represents a significant advancement in the development of improved, less immunogenic animal tissue as a source for transplant into humans. Transplantation is considered to be...

2011-06-30 18:20:22

New research published in the Journal of Leukocyte Biology suggests that overexpressing the human programmed death ligand-1 molecule in pig artery endothelial cells induces human immune tolerance A sizzling genetic discovery by Chinese scientists may one day allow pig tissue to be transplanted successfully into humans. Their research presented in the Journal of Leukocyte Biology (http://www.jleukbio.org) represents a major step forward toward filling the shortage of vital organs for human...

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2009-04-22 15:34:35

Scientists in South Korea have cloned a pig whose organs can be transplanted into humans. Lim Gio-Bin lead the project that resulted in the birth of the cloned piglet to a surrogate mother at the National Institution of Animal Science in Suwon, Gyeonggi Province on April 3. The piglet was designed to lack the "alpha-gal" gene that causes tissue reaction exhibited in immuno-rejection, which has been the primary struggle for human organ transplants in the past. Lim told AFP that his team, which...

2009-01-22 08:41:24

Early attempts at islet cell transplantation to treat diabetes date to the nineteenth century, decades before the discovery of insulin in the 1930s. In recent years, research has focused on the anatomical sites best suited for hosting transplanted islet cells. Experimental sites have included the spleen, liver, peritoneal cavity, omentum, subcutaneous tissues and gastric submucosa. However, many transplant attempts at a variety of anatomical sites have failed because of a variety of...

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2008-12-16 13:40:16

Human and veterinary medicine could receive a big boost through use of larger animals, especially pigs and dogs, in research, with Europe at the forefront. There is the prospect of bringing drugs to the market more quickly at less cost, as well as accelerating progress in other forms of therapy, notably the use of stem cells in regenerative medicine. The potential in this new field was discussed at a recent workshop organized by the European Science Foundation (ESF), which called for a...

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2008-11-07 13:40:00

A professor at Imperial College, London, said on Wednesday that organs from pigs could be widely available for transplanting into patients within a decade. Kidneys would most likely be the first organs suitable for transplanting and are expected to be ready within three years and, if tests are successful, their use could be widespread by 2018. Pigs would be kept as breeding stock to provide organs "to order" and to slash waiting times for thousands of people needing transplants. Professor...

2007-09-11 18:00:00

By Fiona MacRae BRITISH scientists could be breeding designer pigs in just two years that would offer hope to transplant patients. The research, led by fertility expert Professor Lord Robert Winston, eventually aims to breed genetically-modified animals with organs that would not be rejected when transplanted into desperately- ill men and women. The animals would ultimately carry a ready supply of hearts, kidneys, livers and other organs for transplant into humans. Lord Winston is known...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.