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2013-10-23 11:27:14

Genome-wide changes result from silencing extra chromosome, scientists report at ASHG 2013 The first evidence that the underlying genetic defect responsible for trisomy 21, also known as Down syndrome, can be suppressed in laboratory cultures of patient-derived stem cells was presented today (Oct. 22) at the American Society of Human Genetics 2013 annual meeting in Boston. People with Down syndrome are born with an extra chromosome 21, which results in a variety of physical and...

Down's Syndrome Genes Shut Off In New Breakthrough
2013-07-18 05:30:06

Susan Bowen for redOrbit.com - Your Universe Online Scientists at the University of Massachusetts Medical School have made a huge breakthrough in our understanding of Down's syndrome. They reported in the online science journal Nature, that in a lab, they have switched off the extra chromosome that causes the disorder in humans. This is the proof-of-principal that opens the doorway for exciting new discoveries about this condition. Down's syndrome is the world's leading genetically...

2012-03-19 23:03:42

FrontGate Media; the leading faith-based, culture-engaged media & marketing group, announced today the addition of THE MOVE TOUR to their growing internet & events media group roster. This year´s MOVE TOUR 2012 brings together the fierce creative explosion of six of today´s leading voices in music & ministry–BET´s “Sunday Best” favorite Jessica Reedy, Hip Hop generals Da´ T.R.U.T.H. & The Ambassador, R&B/Hip Hop crooner Sean Simmonds,...

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2009-08-24 08:21:19

Mitotic release of chromatin-binding RNA gives insight into X chromosome silencing Early in development, mammalian female cells counteract their double dose of X chromosomes by coating one of them with a large RNA named XIST. The RNA binds to the same X chromosome from which it is transcribed and initiates a series of events leading to the chromosome's permanent silencing. In the August 24, 2009 issue of the Journal of Cell Biology, Hall et al. exploit the fact that XIST temporarily...

2009-07-01 13:51:36

 Because females carry two copies of the X chromosome to males' one X and one Y, they harbor a potentially toxic double dose of the over 1000 genes that reside on the X chromosome. To compensate for this imbalance, mammals such as mice and humans shut down one entire X-chromosome through a phenomenon known as X-inactivation. For almost two decades, researchers have believed that one particular gene, called Xist, provides the molecular trigger of X-inactivation. Now, a new UNC study...


Word of the Day
bodacious
  • Remarkable; prodigious.
  • Audacious; gutsy.
  • Completely; extremely.
  • Audaciously; boldly.
  • Impressively great in size; enormous; extraordinary.
This word is probably from the dialectal 'boldacious,' a blend of 'bold' and 'audacious.'
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