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Latest Ze'ev Ronai Stories

2012-02-03 09:16:18

Study identifies protein kinase C-epsilon as a molecular switch that determines tumor-promoting or -suppressing activity in skin cells The National Cancer Institute (NCI) estimates that as many as one in 51 men and women will be diagnosed with melanoma–the deadliest form of skin cancer–at some point during their lifetimes. A research team led by Ze'ev Ronai, Ph.D. at Sanford-Burnham Medical Research Institute (Sanford-Burnham) is working to unravel the molecular mechanisms...

2011-11-18 02:52:23

Reducing a protein called Siah2 in mice improves mitochondrial response to low oxygen, a condition cells experience when blood flow is restricted during a heart attack Mitochondria are often called cellular "powerhouses" because they convert nutrients into energy. But these tiny structures also help determine cellular lifespan. Scientists at Sanford-Burnham Medical Research Institute (Sanford-Burnham) are now discovering how mitochondria alternate between duplicating and fragmenting and...

2010-12-24 12:59:15

Melanoma is one of the least common types of skin cancer, but it is also the most deadly. Melanocytes (pigment-producing skin cells) lose the genetic regulatory mechanisms that normally limit their number, allowing them to divide and proliferate out of control. One such regulator, called MITF, controls an array of genes that influence melanocyte development, function and survival. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) and their collaborators recently used...

2010-07-15 02:40:09

Researchers reveal that JNK, a protein long known to help cells respond to stress, also controls cell cycle Put simply, a tumor is the result of out-of-control cell growth. To assure that the cell cycle "“ the cell's process of duplicating itself to make more cells "“ goes smoothly, a large network of proteins tells other proteins what to do and when to do it. When any of these layers of protein regulation fail, cell growth can get out of hand. A new study led by Ze'ev Ronai,...

2010-07-13 02:13:45

Researchers uncover a mechanism that determines prostate cancer aggressiveness, providing new targets for diagnosis and treatment Some types of prostate tumors are more aggressive and more likely to metastasize than others. Nearly one-third of these aggressive tumors contain a small nest of especially dangerous cells known as neuroendocrine-type cells. More rarely, some aggressive prostate tumors are made up entirely of neuroendocrine-type cells. The presence of neuroendocrine-type cancer...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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