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Latest Zebrafish Stories

2010-03-24 16:51:47

DURHAM, N.C. "“ Humans have very limited ability to regenerate heart muscle cells, which is a key reason why heart attacks that kill cells and scar heart tissue are so dangerous. But damaged heart muscles in the amazing, highly regenerative zebrafish have given Duke University Medical Center scientists a few ideas that may lead to new directions in clinical research and better therapy after heart attacks. "Our hearts don't seem so complex that they shouldn't have the capacity to...

2010-01-22 00:52:34

By combining the tools of medicinal chemistry and zebrafish biology, a team of Vanderbilt investigators has identified compounds that may offer therapeutic leads for bone-related diseases and cancer. The findings, reported in ACS Chemical Biology, support using zebrafish as a novel platform for drug development. In 2007, Charles Hong, M.D., Ph.D., and colleagues described using fish embryos to screen for compounds that interfere with signaling pathways involved in early development "”...

2010-01-19 12:24:48

Researchers from the University of British Columbia and Harvard University have co-developed a system that captures on video and barcodes the behavioral responses of zebrafish to chemical compounds on a large scale. The approach could dramatically speed up the discovery of new psychiatric drugs. The discovery in the 1950s of drugs that act in the nervous system has been important both for the understanding of neurobiology and the treatment of neurological diseases. Since then, very few new...

2010-01-14 20:25:41

Zebrafish studies reveal pathways affecting sleep and wakefulness that are likely shared with humans A robust new technique for screening drugs' effects on zebrafish behavior is pointing Harvard University scientists toward unexpected compounds and pathways that may govern sleep and wakefulness in humans. Among their more intriguing findings, described this week in the journal Science: Various anti-inflammatory agents in the immune system, long known to induce sleep during infection, may also...

2010-01-08 14:35:00

The zebrafish, a translucent fish often used as a model of human development and disease, offers unique advantages for studying the cause, growth, and spread of tumors using strategies and methods presented in the current "Cancer Biology" special issue of Zebrafish, a peer-reviewed journal published by Mary Ann Liebert, Inc. (http://www.liebertpub.com/). The entire issue is available free online at www.liebertpub.com/zeb Guest Editors Steven D. Leach, MD, the Paul K. Neumann Professor in...

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2009-11-13 08:01:48

Mutation Causing "Leaky" Protein Production Leads to Extra Bone Growth An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton. Reporting in the November issue of the...

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2009-11-04 11:19:04

It's no bigger than a stamp packet but it has the potential to allow rapid development of a new generation of drugs and genetic engineering organisms, and to better control in-vitro fertilization. Engineering researchers at McMaster University have fabricated a palm-sized, automated, micro-injector that can insert proteins, DNA and other biomolecules into individual cells at volumes exponentially higher than current procedures, and at a fraction of the cost. This will allow scientists to...

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2009-11-03 09:22:27

The search for the holy grail of regenerative medicine"”the ability to "grow back" a perfect body part when one is lost to injury or disease"”has been under way for years, yet the steps involved in this seemingly magic process are still poorly understood. Now researchers at the Salk Institute for Biological Studies have identified an essential cellular pathway in zebrafish that paves the way for limb regeneration by unlocking gene expression patterns last seen during embryonic...

2009-10-29 15:04:00

ATLANTA, Oct. 29 /PRNewswire/ -- Zebrafish Technologies announced the release of NetDealroom, its secure, web-based platform enabling sellers of small- to medium-size businesses to efficiently manage the sales process from initial contact through due diligence. NetDealroom offers the same tools utilized in large market transactions but at an affordable price for the small- and medium-size business deal. "This space is becoming highly competitive, as millions of businesses will come to...

2009-10-19 13:31:01

Biologists long have marveled at the ability of some animals to re-grow lost body parts. Newts, for example, can lose a leg and grow a new one identical to the original. Zebrafish can re-grow fins. These animals and others also can repair damaged heart tissue and injured structures in the eye. In contrast, humans have only rudimentary regenerative abilities, so scientists hoping eventually to develop ways of repairing or replacing damaged body parts are keenly interested in understanding in...


Latest Zebrafish Reference Libraries

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2007-04-10 16:14:09

The Giant Danio (Devario aequipinnatus) is a tropical fish belonging to the minnow family (Cyprinidae). Originating in Sri Lanka, Nepal, and the West coast of India, it grows to a maximum length of 6 in (15 cm), making it one of the largest of the Danionins. They are characterized by a blue and yellow torpedo shaped body with gray and clear fins. In the wild, Giant Danios live in clear streams and rivers among hills at elevations up to 1000 ft (300 m) above sea level. Their native...

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2007-04-10 16:07:52

The Zebrafish (Danio rerio) is a tropical fish belonging to the minnow family (Cyprinidae). It is a popular aquarium fish, where it is frequently sold under the trade name Zebra danio, and is also an important model organism. Characteristics The zebrafish arose in the Ganges region in Eastern India and is also native to Pakistan, Bangladesh, Nepal and Myanmar. It commonly inhabits streams, canals, ditches, ponds and slow-moving to stagnant water bodies, including rice fields. The...

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2007-04-10 16:04:19

The Glowlight danio is a small fish with a maximum length of 1.25 in (4 cm). Its coloration is brown, yellow, green and red. The Glowlight can live in waters that are (20-25 degrees Celsius), 6 to 7 pH, with a soft to medium hardness and a low to medium salinity. These fish are compatible with other danios and typically live from 1 to 3 years. They are moderately difficult fish to keep, and breeding can be even harder. Danio choprai or the Glowlight danio is a small, schooling fish...

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Word of the Day
humgruffin
  • A terrible or repulsive person.
Regarding the etymology of 'humgruffin,' the OED says (rather unhelpfully) that it's a 'made-up word.' We might guess that 'hum' comes from 'humbug' or possibly 'hum' meaning 'a disagreeable smell,' while 'gruffin' could be a combination of 'gruff' and 'griffin.'