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Latest Zebrafish Stories

2012-02-13 23:17:58

In medical research, finding a reliable and cost-effective animal model can greatly enhance success in identifying disease mechanisms and genetic pathways, potentially cutting years off drug testing regimes and development of new treatment strategies. Now, University of Massachusetts Amherst neuroscientist Gerald Downes and colleagues have developed just such a model, a mutant zebrafish, to study Maple Syrup Urine Disease (MSUD). It is an inherited metabolic disorder that causes affected...

2012-02-13 08:20:00

AGAWAM, Mass., Feb. 13, 2012 /PRNewswire/ -- A new white paper detailing the new ZET(TM) medical device polymer biocompatibility screening test using Zebrafish embryos is available to download from Microtest Laboratories at http://www.microtestlabs.com/zebrafish-test-paper. The new ZET test was developed by Microtest Laboratories for medical device manufacturers and biomaterials researchers. It utilizes Zebrafish (Danio rerio) to screen plastics, composites, and polymers for toxicity....

2012-01-03 06:13:03

(Ivanhoe Newswire) — Damaged heart tissue typically doesn´t repair itself, but scientists may have identified signals that are able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells. "Despite advances in modern medicine, management of myocardial infarction and heart failure remains a major challenge," senior...

2011-12-22 15:38:48

FINDINGS: Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles during brain development in zebrafish, and went on to show that the human versions of these RNAs can substitute for the zebrafish lincRNAs. RELEVANCE: Despite their prevalence in the cell, lincRNAs have been referred to as the "dark matter" of all the transcribed RNAs because little is known of their functions or mechanisms. Until now, lincRNAs have been...

2011-12-22 15:30:31

Damaged heart tissue is not known for having much inherent capacity for repair. But now, scientists are closing in on signals that may be able to coax the heart into producing replacement cardiac muscle cells. Using a zebrafish model system, researchers have identified a family of molecules that can stimulate stem cells to develop into beating heart muscle cells. The research, published by Cell Press in the December 21st issue of the journal Chemistry & Biology, may pave the way towards...

2011-11-15 19:40:47

After a heart attack, the portions of the heart damaged by a lack of oxygen become scar tissue. Researchers have long sought ways to avoid this scarring, which can harden the walls of the heart, lessen its ability to pump blood throughout the body and eventually lead to heart failure. But new research from the University of North Carolina at Chapel Hill School of Medicine shows that interrupting this process can weaken heart function even further. In a study appearing online November 15,...

Scientists Create Mammalian Cells With Single Chromosome Set
2011-09-08 06:14:18

  Researchers have created mammalian cells containing a single set of chromosomes for the first time in research funded by the Wellcome Trust and EMBO. The technique should allow scientists to better establish the relationships between genes and their function. Mammal cells usually contain two sets of chromosomes — one set inherited from the mother, one from the father. The genetic information contained in these chromosome sets helps determine how our bodies develop. Changes...

2011-09-07 11:15:29

Do animals that have evolved for millions of years underground, completely isolated from the day-night cycle, still "know" what time it is? Does a normal circadian clock persist during evolution under constant darkness? A new study directly tackles these fundamental questions by investigating a species of cavefish, Phreatichthys andruzzii, which has lived isolated for 2 million years beneath the Somalian desert. Many fish species have evolved in the absence of sunlight in cave systems around...

2011-09-02 11:50:14

Loud noise, especially repeated loud noise, is known to cause irreversible damage to the hair cells inside the cochlea and eventually lead to deafness. In mammals this is irreversible, however both birds and fish are able to re-grow the damaged hair cells and restore hearing. New research published in BioMed Central's open access journal BMC Neuroscience shows that growth hormone is involved in this regeneration in zebrafish. Researchers from Western Kentucky University and the University...

2011-09-02 11:40:08

Researchers at the University of Bath have combined genetic data with mathematical modelling to provide insights into cells and how they differentiate. The findings, to be published in open-access journal PLoS Genetics on September 1st, demonstrate the utility of a systems biology approach and could have implications for understanding and treating diseases, including cancers, caused when cells start to function incorrectly. All cells derive from multipotent precursor cells (stem cells)....


Latest Zebrafish Reference Libraries

39_81e6b3dd7e8c07cf1ec882bec90ebb83
2007-04-10 16:14:09

The Giant Danio (Devario aequipinnatus) is a tropical fish belonging to the minnow family (Cyprinidae). Originating in Sri Lanka, Nepal, and the West coast of India, it grows to a maximum length of 6 in (15 cm), making it one of the largest of the Danionins. They are characterized by a blue and yellow torpedo shaped body with gray and clear fins. In the wild, Giant Danios live in clear streams and rivers among hills at elevations up to 1000 ft (300 m) above sea level. Their native...

39_ace37de56045e8be057061f572139540
2007-04-10 16:07:52

The Zebrafish (Danio rerio) is a tropical fish belonging to the minnow family (Cyprinidae). It is a popular aquarium fish, where it is frequently sold under the trade name Zebra danio, and is also an important model organism. Characteristics The zebrafish arose in the Ganges region in Eastern India and is also native to Pakistan, Bangladesh, Nepal and Myanmar. It commonly inhabits streams, canals, ditches, ponds and slow-moving to stagnant water bodies, including rice fields. The...

39_211202e2c1f6a0f9d21546b9ec107c99
2007-04-10 16:04:19

The Glowlight danio is a small fish with a maximum length of 1.25 in (4 cm). Its coloration is brown, yellow, green and red. The Glowlight can live in waters that are (20-25 degrees Celsius), 6 to 7 pH, with a soft to medium hardness and a low to medium salinity. These fish are compatible with other danios and typically live from 1 to 3 years. They are moderately difficult fish to keep, and breeding can be even harder. Danio choprai or the Glowlight danio is a small, schooling fish...

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