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Latest Zinc finger protein transcription factor Stories

2011-09-07 13:49:44

Scientists are reporting development of a long-sought new way to detect the activity of proteins that bind to the DNA in genes, often controlling the activity of genes in ways that make cells do everything from growing normally to becoming cancerous. Their report appears in the Journal of the American Chemical Society. Kevin Plaxco, Francesco Ricci and colleagues note that more than 10 percent of the 25,000-30,000 genes in the human body contain instructions for manufacturing these...

2010-12-13 06:00:00

RICHMOND, Calif., Dec. 13, 2010 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced the publication of preclinical data demonstrating protection of nerve tissue and functional improvements in motor symptoms in a validated rat model of Parkinson's disease (PD) using Sangamo's zinc finger protein (ZFP) technology. As previously disclosed, the study was supported by funding from The Michael J. Fox Foundation for Parkinson's Research (MJFF). The data described in...

2010-11-17 15:00:00

RICHMOND, Calif., Nov. 17, 2010 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today the presentation of Phase 2 clinical data from its ZFP Therapeutic program to develop SB-509, a zinc finger protein transcriptional activator (ZFP-TF) of the vascular endothelial growth factor (VEGF)-A gene as a treatment for ALS. The data from study SB-509-801 demonstrated that the drug was well-tolerated in subjects with ALS and that 40% of SB-509 treated subjects had...

2010-07-01 12:02:00

RICHMOND, Calif., July 1 /PRNewswire-FirstCall/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that it has been awarded a second round of funding by The Michael J. Fox Foundation for Parkinson's Research (MJFF) to support studies in non-human primates for the development of a ZFP Therapeutic(TM) to treat Parkinson's disease (PD). The $900,000 award will be paid over a period of two years. Sangamo has developed zinc finger DNA-binding protein transcription factors (ZFP TFs)...

2010-03-04 16:37:53

Study provides breakthrough blueprint for studying differentiation and evolution In a significant leap forward in the understanding of how specific types of tissue are determined to develop in mammals, an international team of scientists has succeeded in mapping the entire network of DNA-binding transcription factors and their interactions. This global network, indicating which factors can combine to determine cell fate, will be published in the March 5 issue of the journal Cell....


Word of the Day
reremouse
  • A bat.
The word 'reremouse' comes from Middle English reremous, from Old English hrēremūs, hrērmūs ("bat"), equivalent to rear (“to move, shake, stir”) +‎ mouse.
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