December 9, 2013

CUX1: Cancer’s Common Ground

Researchers have identified a gene that drives the development of tumours in over one per cent of all cancer patients. This is the first time that the gene CUX1 has been broadly linked to cancer development.

The team discovered that, when CUX1 is deactivated, a biological pathway is activated that increases tumour growth. Drugs that inhibit the biological pathway are currently being used in the clinic and are in development thus highlighting a potential new targeted therapy for patients with this type of cancer-causing mutation.

Credit: Sanger Institute

[ Read the Article: Genetic Link Associated With One Percent Of All Cancerous Tumors Discovered ]

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