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Xoft to Launch Axxent(R) Xpress(TM) Transportable Electronic Brachytherapy Vehicles at ASTRO Meeting

September 18, 2008

BOSTON, Sept. 18 /PRNewswire/ — Xoft, Inc., developer of the Axxent(R) Electronic Brachytherapy System (eBx), which delivers non-radioactive, X-ray-based radiation treatment directly to cancer sites with minimal exposure to surrounding healthy tissue, announced that it will launch the Axxent Xpress(TM) Mobile Electronic Brachytherapy Vehicles to expand and improve access to critical radiation therapy. The announcement was made in advance of the 49th American Society for Therapeutic Radiology and Oncology (ASTRO) Meeting, September 21-24.

Xoft also announced that it has collaborated with Medical Coaches Inc., a leading manufacturer of custom mobile medical and specialty vehicles, to design and manufacture the specialized medical vehicles, as well as complete the extensive Department of Transportation (DOT) certification process. Xoft and Medical Coaches will showcase an Axxent Xpress Mobile Electronic Brachytherapy Van in a dedicated booth at the ASTRO Meeting.

“Eliminating the need to deliver treatment in heavily shielded vaults, Electronic Brachytherapy was designed to help radiation oncologists improve access to critical cancer care and make it available to patients across geography and socioeconomic levels,” said Michael Klein, president and CEO of Xoft. “Adding the ability to provide mobile radiation therapy services is a natural progression; one we hope will further improve access for the tens of thousands of breast cancer patients who do not comply with their prescribed radiation treatment or otherwise would not receive it. Studies presented at the recent ASCO Breast Cancer Symposium support prior findings that much of this problem is based on inability to access therapy because of distance, fear, or difficulty with the logistics of getting to traditional radiation centers — issues that are addressed with electronic brachytherapy.”

Commercially available for accelerated treatment of early stage breast cancer and endometrial and rectal indications, the Axxent Electronic Brachytherapy System is also cleared for use in the treatment of other cancers or conditions where radiation therapy is indicated. Designed to deliver electronic, X-ray-based radiation treatment, the proprietary Axxent treatment platform can be used in many clinical settings under the supervision of a radiation oncologist, without the need for a shielded room. As a platform technology, the Axxent System addresses a variety of oncological and non-oncological indications and is designed to deliver non-radioactive therapy directly to cancer sites with minimal radiation exposure to surrounding healthy tissue.

In its treatment of early stage breast cancer, the Axxent Electronic Brachytherapy System provides the opportunity to reduce the therapy time required from seven weeks (for external radiation therapy) down to five days. As a result, tens of thousands of patients will have greater access to therapy that is delivered more easily and conveniently. This may accelerate patient choice of breast sparing lumpectomy surgery with adjuvant radiation therapy over the alternative of a full mastectomy.

“Medical Coaches has worked with some of the largest medical companies for decades bringing critical diagnostic and therapeutic equipment to where patients need it most,” said Geoff Smith, president of Medical Coaches. “We are very proud to be working with Xoft on the Axxent Xpress vehicles to help improve access to radiation therapy in outlying and underserved areas.”

The new Axxent Xpress Mobile van has been custom designed by experts from both Xoft and Medical Coaches. The van will be able to carry up to three Axxent System HDR controllers. The controllers will ride on an easy to drive sprinter van modified to provide the safest transport environment. Modifications include ride softening shock absorbers and rear heating and cooling to insure equipment is ready to operate at delivery. A specially built easy to use equipment lift is installed at the rear doors for un-loading and loading sensitive medical equipment. Custom built cabinets and work counters are also supplied for transport of accessories needed to support mobile electronic brachytherapy treatment delivery.

Xoft products will be on display in Booth 1427 in the ASTRO Exhibition Hall and an Axxent Xpress van will be available for viewing in Booth 1457. Xoft will also host an educational symposium in conjunction with the ASTRO Meeting on September 22, where results from its Phase IV study will be presented as well as updates on new electronic brachytherapy applications.

About Medical Coaches

Medical Coaches Inc, http://www.medcoach.com/, is a privately held business that has manufactured more than 20,000 highly specialized mobile medical units located in more than 110 countries since the 1940′s. They have been working together with Siemens Medical Systems, GE Healthcare, and Philips Medical for more than twenty years delivering many mobile MRI, CT, PET and PET/CT coaches to customers throughout the United States. Medical Coaches unique design approach allows them to build the best strength-to-weight ratios in the mobile industry. Each new coach has passed the rigorous testing required by many of the major medical manufacturers to conform to their standards.

About Xoft Inc.

Xoft, founded in 1998, develops Electronic Brachytherapy (eBx) systems based upon miniaturized X-ray tube technology for the practice of radiation oncology in virtually any clinical setting, eliminating the need for heavily shielded environments. Xoft provides a “point of care model” that is patient centric and accessible to a broader spectrum of patients and their physicians. The Axxent treatment platform provides a therapeutic dose of radiation directly to the region at risk with minimal radiation exposure to surrounding healthy tissue and without the complex handling, resource logistics and costs associated with using radioactive isotopes. Xoft aligns with the Nuclear Regulatory Commission’s (NRC) directive to seek alternatives for radioactive medical isotopes. Commercially available for accelerated treatment of early stage breast cancer and endometrial and rectal indications, the Axxent(R) Electronic Brachytherapy System is also cleared for use in the treatment of other cancers or conditions where radiation therapy is indicated. As a platform technology, the Axxent System addresses a variety of oncological and non-oncological indications. For more information, visit http://www.xoftinc.com/.

Axxent is a registered trademark of Xoft, Inc.

Xoft, Inc.

CONTACT: Chad Smith of Medical Coaches, +1-607-432-1333, ext. 125,csmith@medcoach.com; or Chris K. Joseph of Xoft Inc., +1-510-339-2293,chris@ckjcomm.com

Web site: http://www.xoftinc.com/http://www.medcoach.com/




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