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World Intranasal Drug Delivery Market
http://www.reportlinker.com/p092577/World-Intranasal-Drug-Delivery-Market.html
This report analyzes the US market for Intranasal Drug Delivery in US$ Million. The product is analyzed by the following Therapeutic Areas: Allergic Infections, Analgesics, Osteoporosis, and Vaccinations. Annual forecasts are provided for the period of 2000 through 2015. The report profiles 78 companies including many key and niche players such as Aegis Therapeutics LLC, Alza Corporation, AptarGroup, Inc., Archimedes Pharma, AstraZeneca Plc, MedImmune, Inc., Bayer Consumer Care, Bespak Plc, GlaxoSmithKline Plc, Intranasal Therapeutics, Inc., Javelin Pharmaceuticals, Inc., Kurve Technology, Inc., Nastech Pharmaceutical Company, Inc., Novartis AG, OptiNose AS, Pfizer, Inc., Rexam Plc, Schering-Plough Corporation, Sanofi-Aventis S.A., and Unigene Laboratories, Inc. Market data and analytics are derived from primary and secondary research. Company profiles are mostly extracted from URL research and reported select online sources.
INTRANASAL DRUG DELIVERY MCP-1795 A US MARKET REPORT CONTENTS I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS Study Reliability and Reporting Limitations I-1 Disclaimers I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-2 Product Definitions And Scope of Study I-3 II. A US MARKET REPORT 1. Industry Overview II-1 Drug Delivery: A Quick Primer II-1 The Nose: An Attractive Avenue to Cross the Blood Brain Barrier II-1 Self-Administration of Drugs Brings Intranasal Drug Delivery Into the Spotlight II-2 Research & Technology Opens Up New Therapeutic Areas for Nasal Drug Delivery II-2 Recent Product Developments in the US Intranasal Drug Delivery Market (2007) II-2 Table 1: The US Nasal Drug Delivery Market: Sales Of Top Six Nasal Formulations for The Year 2005 (In US$ Million) (includes corresponding Graph/Chart) II-3 R&D: Critical to the Commercialization of Intranasal Drug Delivery II-3 Tight Junction Biology: A Key Speed Breaker in Commercialization II-3 RNA Interference (RNAi): A Tool To Manipulate Tight Junctions II-4 Why Is Nasal Drug Delivery the Theme of All Drug Delivery Research Projects? II-4 Nasal Drug Delivery Devices & Equipments II-4 Preservative Free Systems (P.F.S.) II-4 Traditional Vs Advanced Intranasal Drug Delivery Devices II-6 Pitfalls Of Traditional Delivery Devices II-6 The Promise of New Advanced Delivery Devices II-6 Bi-Directional Nasal Drug Delivery: A Technology With a Huge Potential II-6 Benefits of Bi-Directional Delivery Authenticated Through Research Studies II-7 Market for Nasal Spray Devices in the US II-7 GSK Wields the Leadership Scepter in the US Intranasal Drugs Market II-8 The Batting Order II-8 Table 2: US Market for Intranasal Drug Delivery (2004-2006): Percentage Market Share Breakdown of Leading Players - GlaxoSmithKline, Schering-Plough, AstraZeneca, Sanofi-Aventis, and Others (includes corresponding Graph/Chart) II-8 2. Market Dynamics II-9 Innovation in Drug Delivery: A Talisman For Success II-9 Controlled Release Technology Is the Buzz Word II-9 Target-Specific Delivery Devices: Of Critical Value II-9 Safety and Cost: Primary Growth Drivers II-9 Preservatives Losing Sheen in Nasal Spray Formulations II-10 Multi-Dose Containers Evolve to Offer Resistance Against Microbial Contamination II-10 Bioavailability: An Important Facet of Intranasal Drug Delivery II-10 Chemical Modification II-10 Transient Modification & Limited Enzymatic Activity II-11 Bioavailability of Large Molecules II-11 Bio-Adhesive Polymers: Useful in Increasing Drug Absorption II-11 Mixed Opinions on Efficiency of Calcitonin Nasal Spray II-11 Nasal Preparations Gaining Foothold in Cough and Allergic Categories II-11 Patent Expiries Impact Market Opportunities II-12 3. Technology Overview II-13 Intranasal Drug Delivery: A Descriptive Exposition II-13 Nasal Physiology II-13 Challenges Involved In Formulating Nasal Drugs II-14 The Importance of Bioadhesion II-15 Challenges Involved In Designing Devices II-15 Overview on the Traditional Drug Administration Routes, Molecular Weight Capabilities, and Dosage Range II-15 Intranasal Drugs - Prescription (Rx) and Over-the- Counter (OTC) II-16 Differences Between Systemic Delivery and Local Effects II-16 Nasal Powders Vs Sprays II-16 Nasal Drug Delivery Devices II-17 Types of Drug Delivery Devices II-17 Droppers II-17 Sprays II-17 Aerosol Containers/Inhalers II-17 Pumps II-18 Nasal Aspirator II-18 Intranasal Drug Delivery Vis-a-vis Other Delivery Techniques II-18 Table 3: US Market for Intranasal Drugs: Percentage share of Topical and Systemic Drugs by value for the Years 2006 and 2012 II-18 Limitations of Intranasal Drug Delivery II-19 Allergy II-19 Definition II-19 Symptoms II-19 Allergic Rhinitis II-20 Nasal Allergies II-20 Table 4: US Market for Nasal Sprays, Drops and Inhalers: Top 10 Brands Ranked by Dollar Sales Through Drug Stores for the Year Ended January 2008 (In US $ Million) (includes corresponding Graph/Chart) II-20 Table 5: US Market for Nasal Sprays, Drops and Inhalers: Top 10 Brands Ranked by Unit Sales Through Drug Stores for the Year Ended January 2008 (In Thousand Units) (includes corresponding Graph/Chart) II-21 Table 6: US Market for Nasal Sprays: Top Five Nasal Sprays for Cough, Cold, Sinus and Allergy Ranked by Dollar Retail Sales for the Year Ended January 2008 (In US $ Million) (includes corresponding Graph/Chart) II-21 4. Nasal Drugs: An Overview II-22 Nasal Drugs For Allergies II-22 Corticosteroid Nasal Sprays II-22 Flonase II-22 Patanase II-22 Beconase II-22 Other Nasal Corticosteroid Drugs II-23 Antihistamine Nasal Sprays II-23 Astelin Nasal Spray II-23 Otrivin Nasal Spray II-23 Livostin Nasal Spray II-23 Other Nasal Antihistamine Drugs II-23 Other Brands of Allergy Relievers II-24 Nasal Drugs for Postmenopausal Osteoporosis II-24 Calcitonin-Salmon Nasal Spray II-24 Miacalcin Nasal Spray II-24 Fortical(R) Nasal Spray II-24 Intranasal Pain Management Drugs II-24 Stadol Nasal Spray II-25 Rylomine II-25 Imitrex II-25 Migranal II-26 Zolmitriptan Nasal Spray II-26 Intranasal Analgesics For Treating Migraine II-26 Select Intranasal Pain Management Products in Development II-26 Intranasal Vaccination II-27 Process of Intranasal Immunization II-27 Market Drivers II-28 "LAIV" Nasal Spray Flu Vaccine II-28 FluMist(R) Vaccine From MedImmune II-28 Intranasal Drugs for Sexual Dysfunction II-29 Table 7: US Market for Intranasal Drugs: Projected Revenues for Intranasal Sexual Dysfunction Drugs for the Years 2010 through 2012 in US$ Million (includes corresponding Graph/Chart) II-29 Nasal Spray for Treating Vitamin B12 Deficiency II-30 Nasal Spray for Aiding Smoking Cessation II-30 Intranasal Drugs In the Pipeline II-30 5. Research & Development II-31 Nastech Enrolls 551 Patients for Phase 2 Trials of PYY3-36 Nasal Spray II-31 Archimedes Pharma Commences Phase III Trials for NasalFent(R) II-31 Archimedes Presents New Clinical Data on NasalFent(R) II-31 LigoCyte Commences Clinical Trials for Intranasal Norovirus Vaccine II-31 Javelin Pharmaceuticals Reveals Phase 2 Study Results for PMI-100/150 II-31 Javelin Pharmaceuticals Commences Phase III Studies for PMI-150 II-32 Nastech Commences Phase 2 Trials for Insulin Nasal Spray II-32 ACAAI Reveals Results for Trials of Nasacort(R) AQ Nasal Spray in Children II-32 TGAR01H from Fabre Kramer II-33 Aegis Therapeutics Completes First Human Clinical Study on Intravail(R) II-33 Nastech Pharmaceutical Presents Clinical Test Results on Parathyroid Hormone II-33 Zolmitriptan Promises Relief for Cluster Headaches II-33 CAIV-T: More Effective than Injectable Influenza Vaccines II-34 Intranasal Therapeutics Conducts Study on Midazolam II-34 Nastech Announces Phase I Results of Insulin Nasal Spray II-34 Archimedes Completes Phase II Trials of NASALFENT II-35 Intranasal Corticosteroid Proven Effective for Treating Allergic Rhinitis II-35 Aegis Files DMF for Intravail II-35 Nasal Sprays: A New-Generation Treatment for Gynecological Problems II-35 Aegis Therapeutics Conducts Feasibility Study on Drug Delivery Technology II-36 GelVac Powder Delivery System Completes Phase I Clinical Trial II-36 DelSite Files DMF with the FDA II-37 OptiNose Develops Intranasal Delivery System for Osteoporosis II-37 Nastech Initiates Dose Ranging Study of PYY(3-36) II-37 Valois Develops New Nasal Dispensing System II-37 Rigel Pharmaceuticals to Initiate R112 Phase II Clinical Trial II-38 MedPointe Pharmaceuticals Demonstrates ACT1 Study Results on ASTELIN(R) II-38 Bentley Pharmaceuticals Demonstrates Clinical Trial Results of its Intra Nasal Insulin Spray II-38 6. Recent Technological Developments II-39 New-Generation Technologies and Devices II-39 ViaNase from Kurve Technology II-39 A New Product from OptiNose II-39 Nastech's "Tight Junction Biology" Research Program II-40 ChiSys(TM) Nasal Delivery Technology from Archimedes II-40 7. Product Innovations/Introductions II-41 Aegis Therapeutics Develops ProTe k(TM) II-41 Heel Launches Luffeel(R) in the US II-41 Palatin Technologies to Develop Bremelanotide II-41 Archimedes to Introduce Intranasal Formulation of Human Growth Hormone II-41 Sinofresh Launches SinoFresh(TM) Nasal & Sinus Care II-41 PARI Respiratory Launches Nasal Drug Delivery Program II-42 OptiNose to Develop New Range of Intranasal Products II-42OptiNose and Cambridge Consultants to Develop Advanced Nasal Delivery Device II-42 Kurve Technology Develops ViaNase ID(TM) II-42 Upsher-Smith Introduces Fortical(R) Nasal Spray II-43 Schering-Plough Launches New Formulation of NASONEX(R) II-43 AstraZeneca Unveils Rhinocort Aqua in the US II-43 8. Recent Industry Activity II-44 Zelos Therapeutics Collaborates with Aegis Therapeutics II-44 ImmuneRegen BioSciences Partners with LRRI II-44 Avamys(TM) Nasal Spray Receives Approval in Europe II-44 PMI-150 Receives Canadian Patent II-44 USFDA Approves FluMist(R) for Young Children II-45 USFDA Approves Veramyst Nasal Spray for Individuals Aged Two Years and Above II-45 Kurve Technology Inks Agreement with Schering-Plough II-45 MedImmune Clarifies FDA Observations II-45 FluMist(R) Receives FDA Approval for Refrigerated Formulation II-45 Nastech Regains Rights for PTH1-34 Nasal Spray II-45 NASONEX(R) Receives Ease-of-Use Commendation from Arthritis Foundation II-46 Aegis Therapeutics Establishes Cedar Therapeutics Inc. II-46 EMEA Provides Encouraging Feedback for Avamys(TM) Nasal Spray II-46 Kurve Technologies Introduces Blog on Nasal Drug Delivery II-46 Accentia Extends Agreement with Mayo Foundation II-46 Nastech Signs Development and License Agreement with Amylin II-47 MedImmune's FluMist Plant Gets FDA Approval II-47 ShinNippon Subsidiaries Sign Licensing Agreement with Tokai Pharmaceuticals II-47 MeadWestvaco Acquires Saint-Gobain Calmar II-47 Merck Terminates PYY3-36 Partnership with Nastech II-47 Inspire Signs Licensing Agreement with Boehringer Ingelheim II-48 P&G Partners with Nastech to Develop PTH(1-34) II-48 Unigene Laboratories Signs Distribution Agreement with Tzamal Bio Pharma II-49 GlaxoSmithKline Seeks Marketing Approval for Fluticasone Furoate in the US and Europe II-49 Kurve Technology Relocates Corporate Headquarters II-49 Kurve Inks an Agreement with DARA BioSciences II-49 Kurve Enters into a Development Agreement with Schering-Plough II-49 Altana Submits NDS for Approval of Ciclesonide Nasal Spray in Canada II-49 Altana Pharma AG Receives FDA Approval for Pediatric Use of Omnaris II-50 Intranasal Therapeutics Inc. Receives Financial Funding II-50 FDA Completes Pre-Approval Inspections at Nastech's Washington Facility II-50 Kos Signs Exclusive License Agreement with SkyePharma II-50 Bentley Signs Agreement with Biocon II-50 MedImmune Files New Drug Application with the FDA II-51 Intranasal Therapeutics Files Patent Application for Synthetic THC II-51 Ionix Pharmaceuticals in Collaboration with Reckitt Benckiser for Drug Development II-51 University of Kentucky Receives Patent for new Intranasal Device II-51 Intranasal Technology Extends Collaboration with Aegis Therapeutics II-52 Accentia Biopharmaceuticals Signs License Agreement with Collegium Pharmaceuticals II-52 Aegis Therapeutics Extends License Agreement with Intranasal Technologies II-52 Bentley Pharmaceuticals Signs Agreement with Dong Sung Pharmaceuticals II-52 Unigene Gets FDA Approval for Fortical Calcitonin- Salmon Nasal Spray II-53 OptiNose Signs Collaborative Agreement with MedPharm II-53 West Pharmaceutical Divests Drug Delivery Business to Archimedes Pharma II-53 Nastech Pharmaceutical Receives FDA Approval for Nascobal Nasal Spray II-53 Par and Nastech Sign Licensing Agreement II-53 Aegis Therapeutics Signs Licensing Agreement with University of Alabama II-54 ITI Receives a Patent for Sedation Inducing Nasal Drug II-54 Inyx Bags Order from Australian OTC Drug Company II-54 9. Focus on Select Global Players II-55 Aegis Therapeutics LLC (USA) II-55 Alza Corporation (USA) II-55 AptarGroup, Inc. (USA) II-55 Archimedes Pharma Limited. (UK) II-56 AstraZeneca Plc (UK) II-56 MedImmune, Inc. (USA) II-56 Bayer Consumer Care (USA) II-57 Bespak Plc (UK) II-57 GlaxoSmithKline Plc (UK) II-57 Intranasal Therapeutics, Inc. (USA) II-58 Javelin Pharmaceuticals, Inc (USA) II-58 Kurve Technology, Inc. (USA) II-58 Nastech Pharmaceutical Company, Inc. (USA) II-58 Novartis AG (Switzerland) II-59 OptiNose AS (Norway) II-59 Pfizer, Inc. (USA) II-59 Rexam Plc (UK) II-60 Schering-Plough Corporation (USA) II-60 Sanofi-Aventis S.A. (France) II-60 Unigene Laboratories, Inc. (USA) II-60 10. Market Analytics II-61 Table 8: US Recent Past, Current & Future Analysis for Intranasal Drug Delivery by Therapeutic Area - Allergic Infections, Analgesics, Osteoporosis, and Vaccinations Markets Independently Analyzed by Annual Sales Figures in US$ Million for Years 2000 through 2010 II-61 Table 9: US Long-term Projections for Intranasal Drug Delivery by Therapeutic Area - Allergic Infections, Analgesics, Osteoporosis, and Vaccinations Markets Independently Analyzed by Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart) II-61 Table 10: US 10-Year Perspective for Intranasal Drug Delivery by Therapeutic Area -Percentage Breakdown of Values Sales for Allergic Infections, Analgesics, Osteoporosis, and Vaccinations for Years 2003, 2008 & 2012 (includes corresponding Graph/Chart) II-62 III. COMPETITIVE LANDSCAPE
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World Intranasal Drug Delivery Market
http://www.reportlinker.com/p092577/World-Intranasal-Drug-Delivery-Market.html
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