Climate Woes Continue: Changes In Polar Bear Diet Result In Higher Toxin Exposure

Brett Smith for redOrbit.com – Your Universe Online

Warmer than average Arctic temperatures in recent years have been stirring up all kinds of ecological changes and a new study in the journal Global Change Biology indicates that polar bears could be getting exposed to higher levels of toxins as a result.

The study looked at an East Greenlandic population of polar bears, which is expected to enjoy the Arctic sea ice far longer than other regions. However, the loss of ice sheet cover in these waters occurs at a rate of nearly 1 percent per year, one of the highest rates across the entire Arctic.

To see how the changes have affected the bears, a team of international scientists examined the fatty acid composition of adipose tissue collected from 310 polar bears hunted by East Greenland Inuits from 1984 to 2011. The makeup of fatty acids in the adipose tissue samples reflected the profile of fatty acids in the bears’ prey.

The researchers saw that the bears mostly fed on three species of seals: the ringed seal, which inhabits the Arctic, and the two sub-Arctic species – the harp seal and hooded seal. The study’s results also showed that the polar bears have significantly changed their diet over the nearly 30 years covered by the samples.

Over the study period, the ringed seal’s significance for the polar bears diet dropped by 42 percent as the bears’ intake of the sub-Arctic seals increased. The team also found that polar bears are generally in better shape now.

At first glance, the polar bears would seem to be better off these days. However, a deeper analysis revealed several problems.

“The problem is that the sub-Arctic seals that the polar bear has switched to, have a higher content of contaminants because they live closer to the industrialized world and are higher up in the food chain,” explained study author Rune Dietz, a biology professor at Aarhus University. He added that climate change undermines the improvements that they would otherwise have obtained owing to international regulations in the environmental use of persistent organic pollutants (POPs). They determined that the content of the POPs after year 2000 decreased more slowly in the polar bear than in the ringed seal.

Although warmer temperature may mean these sub-Arctic seals are traveling farther north, the researchers said the long-term prospects for accessing these seals could decline as they depend on packed ice to birth their cubs and receive vital vitamin D-forming sunlight.

While polar bears off the coast of Greenland may be enjoying a greater, albeit more polluted, variety of food, their counterparts in northern Canada and off the coast of Alaska appear to be less well off.

Recent research has found that these bears have been exhibiting lowered reproductive abilities, lowered average body weight and decreases in overall population.

Based on a study published earlier this month by Global Change Biology, a team of American and Canadian researchers said an array of environmental differences are affecting the health of polar bears in East Greenland.

Antibiotics Driving Resistant Bacteria In Urban Sewers

Brett Smith for redOrbit.com – Your Universe Online

A new study from Chicago-based researchers has found that a confluence of sewage overflows and widespread antibiotic use is causing the proliferation of antibiotic-resistant bacteria in waterways around the Windy City.

Recently published in the journal Environmental Science and Technology, the study looked at the antibiotic triclosan, which is in about half of liquid soaps and functions by slowing or stopping the growth of bacteria, fungi, and mildew. Triclosan frequently gets into streams and rivers through domestic waste-water, leaky sewers and sewage overflows.

“The bacterial resistance caused by triclosan has real environmental consequences,” said study author Emma Rosi-Marshall, an aquatic ecologist at the Cary Institute of Ecosystem Studies in Millbrook, New York. “Not only does it disrupt aquatic life by changing native bacterial communities, but it’s linked to the rise of resistant bacteria that could diminish the usefulness of important antibiotics.”

In the study, researchers collected samples at three sites in the Greater Chicago area: the urban North Shore Channel, the suburban West Branch Dupage River, and the rural Nippersink Creek. The team found a correlation between urbanization and a rise in both triclosan concentrations in sediments and the ratio of bottom-dwelling bacteria resistant to the antibiotic. The rural creek had the lowest levels of triclosan-resistant bacteria, while the urban site sampled downstream of 25 combined sewer overflows had the highest levels.

Combined sewers ferry sewage, industrial wastes, and storm water to a treatment plant using a single pipe. When excessive runoff from high rainfall or snowmelt gets into these sewers, the overflows that result send untreated sewage flowing directly into rivers and streams.

The Chicago researchers found that their local sewer overflows are a major source of triclosan pollution in the North Shore Channel. The team’s findings also support previous work that suggests sewage treatment plants can efficiently remove triclosan from wastewater.

“We detected much lower levels of triclosan at a site downstream of a sewage treatment facility as compared to a site downstream of combined sewer overflows,” said John Kelly of Loyola University Chicago. “And we demonstrated a strong link between the presence of triclosan in the environment and the development of triclosan resistant bacteria.”

Almost 800 cities in the United States use combined sewer overflows, an infrastructure feature that the Environmental Protection Agency cites as a major water pollution concern.

The study researchers also conducted artificial stream experiments at Loyola to confirm field tests that indicated triclosan exposure triggers an increase in triclosan-resistant bacteria. In addition to the proliferation of resistant bacteria, researchers also saw a drop in the diversity of river-bottom bacteria and a change in the makeup of bacterial communities. The researchers noted a six-fold increase in cyanobacteria and a spectacular die-off of algae.

“Cyanobacteria are less nutritious than algae and can produce toxins,” Rosi-Marshall explained. “In triclosan-polluted streams and rivers, changes in microbial communities could negatively affect ecological function and animal communities.”

The study is the latest result of study researchers’ on-going effort to learn more about the ecological and human health consequences of synthetic antimicrobials.

Vitamin B Effects On Stroke Risk May Be Bittersweet

[ Watch the Video: Stroke Risk May Be Reduced With Vitamin B Regimen ]

Michael Harper for redOrbit.com – Your Universe Online

There’s currently a debate about the effectiveness of vitamin B in reducing strokes and heart attacks, with some saying diets rich in B vitamins may actually increase one’s risk of stroke.

New research, however,  suggests vitamin B reduces the risk of stroke by seven percent, though it does not reduce the severity of a stroke or the risk of death from a stroke. A group of researchers from Zhengzhou University in China completed this recent study and say they saw a reduction in strokes when people took plenty of B vitamins, but they did not note any significant reduction in risk of heart attack. This research has been published in the journal Neurology.

Lead author Xu Yuming and team analyzed data collected from nearly 55,000 participants who were either taking vitamin B supplements, a placebo, or a very low dose of vitamin B. During the sixth month study period, 2,471 of these patients had a stroke. Each of the stroke victims saw some benefit from taking the B vitamins, though the researchers did note their strokes weren’t any less severe than the others. Vitamin B has been found to lower homocysteine levels, a molecule in the blood which aids in blood clotting. With lower levels of this molecule, the risk of a clot running through the blood stream and lodging in the brain is thereby reduced.

“Our analysis demonstrated that homocysteine lowering therapy with B vitamin supplementation significantly reduced stroke events,” said Yuming in a statement, as cited by The Telegraph’s Richard Gray.

There are other ways to get B vitamins into the body other than supplements, of course. Vitamin B, a grouping of 8 vitamins, can be found in unprocessed foods and meat. Foods like beef, cheese, crustaceans, eggs, fish and even fortified cereals and soy are all high in B vitamins.

According to the research, different types of B vitamins can affect the body in different ways.

Yuming and his team found folic acid, or B9, may reduce the positive effects of taking a vitamin B supplement. Vitamin B12, for instance, did not reduce the risk of stroke in any of the participants. According to Yuming, these changes are largely dependent on the individual taking the supplements.

“Based on our results, the ability of vitamin B to reduce stroke risk may be influenced by a number of other factors such as the body’s absorption rate, the amount of folic acid or vitamin B12 concentration in the blood, and whether a person has kidney disease or high blood pressure,” said Yuming.

“Before you begin taking any supplements, you should always talk to your doctor,” added Yuming.

Previous research has shown B vitamins can be helpful in repairing the brain following a stroke as opposed to preventing it altogether.

Researchers at Henry Ford Hospital claimed in 2010 that vitamin B3, or niacin, can help repair neurological function following a stroke.

The team claim niacin worked in this way because it increased the amount of “good” cholesterol in the brain, thereby increasing blood vessel size and deliver more blood to the brain.

How To Order A Drink When Your Bartender Is A Robot

Michael Harper for redOrbit.com – Your Universe Online

German scientists are looking to improve human to robotic interaction by setting the two up together at the bar.

Modern science has already produced more than one robotic bartender capable of pouring spirits into cups, giving them a shake and serving them up to thirsty bar patrons. These bartenders have to be told what to do via smartphone app, however, and cannot anticipate when someone wants a refill.

Professor Jan de Ruiter with Bielefeld University in Germany has been working to improve robotic technology to the point where the machines can recognize visual cues and body language — but first he had to understand it himself. He and his team of researchers studied the way people order drinks at the bar and found the most effective way is also the simplest — walking directly to the bar, looking square at the bartender, and asking for a drink.

Dr. Ruiter’s research is now published in the journal Frontiers in Psychology.

What the research team has learned is being programmed into a robotic bartender called James, or Joint Action in Multimodal Embodied Systems. The apron-less robot has a spartan figure with a torso that spins on a rotator and a single arm with a hand for grasping drinks. Dr. Ruiter’s team use an iPad for James’ head, and a pair of large cartoonish eyes and a thin smile make up his face on the tablet screen.

As customers approach James’ bar, cameras can recognize their facial expressions as microphones listen to the drink order. James then goes to work, reaching for the drink with a four-fingered hand. In a video James is only seen grabbing plastic bottles and doesn’t actually mix any cocktails or pull a beer from the tap.

“In order to respond appropriately to its customers the robot must be able to recognize human social behavior,” said Dr. Ruiter in a statement. “Currently, we are working on the robot’s ability to recognize when a customer is bidding for its attention. Thus, we have studied the process of ordering a drink in real life.”

Without a clear direction and definition of facial cues and body language, James might never pour a beer for a patron.

To understand how people order drinks, Dr. Ruiter’s team set up video cameras in clubs and pubs in Germany and the United Kingdom and analyzed the way people ordered. They found few people actually signal a bartender by fidgeting with or looking at their wallet. Even fewer people were served when they were looking at a menu or drink list. The most effective way to get a bartender’s attention and be served a drink, say the researchers, is the direct approach.

“Two signals are necessary and together form the sufficient set of signals for identifying the intention to place an order,” Dr. Ruiter told the Telegraph.

“First, the customers position themselves directly at the bar and, secondly, look at the bar/bartender. If one of these signals was absent, the participants judged the customers as not bidding for attention. This provided a clear indication that both signals are necessary for bidding for attention.”

After analyzing their research, the scientists found 95 percent of all customers who received their drinks within 35 seconds directly confronted the bartender in this way.

Dr. Ruiter and team have now programmed James with this information and say the robot can understand when a customer is ready to place an order. James has also been programmed to work on a first-come-first-served basis and will ignore anyone who cuts in line.

The researchers have been working on James since early 2011 and hope to have the project completed in January 2014.

The History of 3D Printing

Three-dimensional printing, also known as additive manufacturing, is the process of using additives to form solid 3D objects of virtually any shape from a digital model. This is achieved using specially formulated additives, such as plastics, that are formed into successive layers of material typically laid down on a platform in different shapes. 3D printing is uniquely distinct from a more traditional 3D sculpting technique, which relies on the removal of layers (subtractive manufacturing) to produce a three-dimensional object.

While 3D printers have recently been thrust into the spotlight with several startups, such as MakerBot, producing printers capable of turning digital models into real-world objects, these have not been the first such tools to find their way to market.

The first published account of a printed solid model was made by Hideo Kodama of Nagoya Municipal Industrial Research Institute in 1982. The first working 3D printer was created in 1984 by Charles W. Hull of 3D Systems Corp. Hull published a number of patents on the concept of 3D printing, many of which are used in today’s additive manufacturing processes. Of course, 3D printing in the early days was very expensive and not feasible for the general market. As we moved into the 21st century, however, costs drastically dropped, allowing 3D printers to find their way to a more affordable market.

The cost of 3D printers has even decreased in the years from 2010 to 2013, with machines generally ranging in price from $20,000 just three years ago, to less than $1,000 in the current market. Some printers are even being developed for under $500, making the technology increasingly available to the average consumer.

APPLICATIONS

Since becoming mainstream, 3D printing has worked its way into a number of markets. The technology is now used in prototyping and distributed manufacturing with applications in architecture, construction, industrial design, automotive design, aerospace, military, engineering, etc. It has also become popular in areas such as dental and medical technology, fashion, footwear, jewelry, eyewear, and more. Interestingly, even food may one day be printed, which may help feed the ballooning population.

As the technology advances, more and more practical uses are expected to come about as a result of additive manufacturing. With the addition of 3D digitizers, 3D sensors and 3D scanners, the possibilities are almost endless.

Recently, NASA has been testing rocket parts built by 3D printing and may even use the technology to build habitats in space and on other worlds.

And along with the many useful everyday things that 3D printers can give us, medical researchers are now using 3D-printed technologies to save human lives.

Get the History of 3D Printing e-book at Amazon.com

Image Credit: Thinkstock.com

Additive Found In Dog Food May Prevent A Disabling Chemotherapy Side Effect

April Flowers for redOrbit.com – Your Universe Online

A chemical commonly used as a dog food preservative might prevent the kind of painful nerve damage found in the hands and feet of four out of five cancer patients taking the chemotherapy drug Taxol.

A team of Johns Hopkins researchers have been working with cells in test tubes and mice to investigate the Food and Drug Administration (FDA)-approved dog food preservative. The preservative, an antioxidant called ethoxyquin, has been shown to bind certain cell proteins in such a way that their exposure to the damaging effects of Taxol is limited.

The researchers hope that their findings, published online in the Annals of Neurology, will help to build on the protective effects of ethoxyquin’s chemistry.

Scientists could possibly develop a drug that could be given to cancer patients before taking Taxol, in much the same way that anti-nausea medication is given to stave off the nausea that commonly accompanies chemotherapy. Currently, approximately half of Taxol users recover from the pain damage, known as peripheral neuropathy. The other half often continue to have debilitating pain, numbness and tingling for the rest of their lives.

“Millions of people with breast cancer, ovarian cancer and other solid tumors get Taxol to treat their cancer and 80 percent of them will get peripheral neuropathy as a result,” says Ahmet Höke, MD, PhD, a professor of neurology and neuroscience at the Johns Hopkins University School of Medicine and director of the Neuromuscular Division. “They’re living longer thanks to the chemotherapy, but they are often miserable. Our goal is to prevent them from getting neuropathy in the first place.”

Prior studies have shown that adding Taxol to a nerve cell line growing in a petri dish would cause neurodegeneration. Höke and his team added Taxol and some 2,000 chemicals — one at a time — to see which, if any, might interrupt the degenerative process.

Ethoxyquin did exactly that by making the nerve cells resistant to the toxic effects of Taxol.

Once ethoxyquin’s effects were identified in the laboratory grown cell lines, the research team gave Taxol to mice intravenously. They observed nerves in the mice’s paws degenerate in only a couple of weeks. When they gave the mice ethoxyquin at the same time as the Taxol, however, it prevented two-thirds of the nerve degeneration. According to Höke, this would have a big impact on quality of life if the same effects were to occur in humans.

Molecules of ethoxyquin bind to Hsp90, which is one of the “heat shock” proteins that cells defensively make more of whenever they are stressed. Basically, Hsp90 is the cell’s quality control officer. It determines whether a protein is properly formed before sending it out where it is needed. The team discovered that when ethoxyquin binds to Hsp90, two other proteins — ataxin-2 and Sf3b2 — can’t. This forces the cell to see these two proteins as flawed, so they are degraded and their levels in the cell diminished.

So far, the team is unsure why an excess of these two proteins cause a negative effect on nerves, but it is clear that reducing their levels appears in their studies to make cells more resistant to Taxol toxicity.

The team is continuing their investigation into whether this medication might also make nerves more resistant to damage in peripheral neuropathy caused by HIV and diabetes, two other major causes of the pain.

According to Höke, a prior study revealed that ataxin-2 may cause degeneration in motor neurons in a rare form of ALS, commonly known as Lou Gehrig’s disease, suggesting that ethoxyquin or some version of it might also benefit people with this disorder.

Peripheral neuropathy affects between 20 and 30 million Americans, making it a “huge public health issue.” Höke says that it doesn’t receive much attention because it is not fatal.

The team would like to continue their research by conducting safety studies with ethoxyquin in animals in advance of possible testing in people. While too much ethoxyquin is thought to be potentially harmful to dogs, Höke says the needed dose for humans would likely be 20-to-30-fold lower than what is found in dog food.

Ethoxyquin was originally developed in the 1950s as an antioxidant to prevent pears and other foods from discoloring and spoiling.

Mice Aren’t Scaredy-Cats When Infected By Toxoplasma

Brett Smith for redOrbit.com – Your Universe Online

Known to cause spontaneous abortions in pregnant women or death in immune-compromised patients, the parasite Toxoplasma gondii has an even stranger effect in mice – it takes away their fear of cats. The fearless mice are a boon to both cats, which get an easy meal, and the parasite, which gets access to the cat’s intestinal track – the only place the parasite can sexually reproduce.

According to a new University of California, Berkeley study, published in the journal PLoS ONE, the parasite’s effect on cats seems to be permanent –after the mouse recovers from the initial flu-like symptoms of toxoplasmosis and even months after the parasitic infection is cleared from the body.

“Even when the parasite is cleared and it’s no longer in the brains of the animals, some kind of permanent long-term behavior change has occurred, even though we don’t know what the actual mechanism is,” said study author Wendy Ingram, a graduate researcher at UC Berkeley.

Ingram said the parasite could affect the mouse brain so that the scent of cat urine can’t be detected. The parasite may also be affecting neurons involved in memory and learning or it could trigger a response from its host that affects the natural fear response.

The Berkeley team began by seeing if parasite-hosting mice avoided bobcat urine, a normal response in uninfected mice, versus rabbit urine, which mice typically ignore. While mice typically lose their fear of bobcat urine for a few weeks after initial infection, the researchers found that the three most common strains of Toxoplasma gondii eliminate the fear response to cats for at least four months.

Using a genetically modified strain of Toxoplasma that was unable to cause chronic infections in the mouse brain, the team showed that the behavioral effect still took hold and lasted for four months after the mice eliminated the microbe from their bodies.

“This would seem to refute – or at least make less likely – models in which the behavior effects are the result of direct physical action of parasites on specific parts of the brain,” study author and Berkeley professor Michael Eisen wrote in a blog post about the research.

“The idea that this parasite knows more about our brains than we do, and has the ability to exert desired change in complicated rodent behavior, is absolutely fascinating,” Ingram said. “Toxoplasma has done a phenomenal job of figuring out mammalian brains in order to enhance its transmission through a complicated life cycle.”

The team said they are currently looking at how the mouse immune system responds to the parasite to determine if the response or the infection is causing the behavioral change.

About one-third of people around the world are thought to be infected with Toxoplasma and have dormant cysts in their brains being kept in check by their body’s immune system. These cysts may spring to life in immune-compromised people, resulting in death. Some preliminary studies indicate that chronic infection may be associated with schizophrenia or attempted suicide.

Because the parasite can be passed via cat feces and infect a developing fetus, pregnant women are warned to avoid kitty litter. Another source of spread is undercooked pork, Ingram noted.

Sharks Play Critical Role In Coral Reef Health

Brett Smith for redOrbit.com – Your Universe Online

Sharks play an important role in the food web of a marine ecosystem and a study recently published in the journal PLOS ONE has found that overfishing of these predators can have a disruptive effect on coral reefs.

“Where shark numbers are reduced due to commercial fishing, there is also a decrease in the herbivorous fishes which play a key role in promoting reef health,” said study author Jonathan Ruppert, a marine ecologist with the University of Toronto.

Co-author Mark Meekan of the Australian Institute of Marine Science (AIMS) said that the team’s finding might seem strange at first given that sharks and coral reefs seem to be completely unconnected.

“However our analysis suggests that where shark numbers are reduced, we see a fundamental change in the structure of food chains on reefs,” he said. “We saw increasing numbers of mid-level predators – such as snappers – and a reduction in the number of herbivores such as parrotfishes.”

“The parrotfishes are very important to coral reef health because they eat the algae that would otherwise overwhelm young corals on reefs recovering from natural disturbances.”

To reach their conclusion, the team of Canadian and Australian scientists conducted a long-term monitoring program of coral reefs off Australia’s northwest coast. The reefs sit about 190 miles off the coast of Australia where sharks are targeted by Indonesian fishers. For several centuries, sharks have been hunted in these waters under an Australian-Indonesian memorandum of understanding.

“Going by our surveys, around four sharks a day were being taken from these reefs,” Meekan told the Guardian. “This doesn’t sound like a lot, but it has been going on for a long time. The fishermen come in their sailing prows, which can dry an awful lot of shark fin on the decks.”

“The reefs provided us with a unique opportunity to isolate the impact of over-fishing of sharks on reef resilience, and assess that impact in the broader context of climate change pressures threatening coral reefs,” Ruppert noted.

“Shark fishing appears to have quite dramatic effects on coral reef ecosystems. Given that sharks are in decline on reefs worldwide, largely due to the shark fin trade, this information may prove integral to restoration and conservation efforts.”

In their report, the researchers said the complex web of prey-predator interactions surrounding coral reefs makes uncovering a specific apparatus linking sharks and corals very difficult.

“Despite the correlation between shark abundance and herbivores, we could not show the mechanism that linked these trophic levels,” the scientists wrote.

Previous studies have shown that reef sharks are closely linked to certain coral reefs, meaning that small, well-targeted protected areas could effectively protect both apex predators and the reefs themselves.

This new study comes as coral reefs are under pressure from direct human activities, as well as the impact of climate change. The use of small protected areas would allow coral reefs to be able to recover from large storms, which some scientists say are increasing in frequency and strength.

Scaling Up Personalized Query Results For Next Generation Of Search Engines

North Carolina State University researchers have developed a way for search engines to provide users with more accurate, personalized search results. The challenge in the past has been how to scale this approach up so that it doesn’t consume massive computer resources. Now the researchers have devised a technique for implementing personalized searches that is more than 100 times more efficient than previous approaches.

At issue is how search engines handle complex or confusing queries. For example, if a user is searching for faculty members who do research on financial informatics, that user wants a list of relevant webpages from faculty, not the pages of graduate students mentioning faculty or news stories that use those terms. That’s a complex search.

“Similarly, when searches are ambiguous with multiple possible interpretations, traditional search engines use impersonal techniques. For example, if a user searches for the term ‘jaguar speed,’ the user could be looking for information on the Jaguar supercomputer, the jungle cat or the car,” says Dr. Kemafor Anyanwu, an assistant professor of computer science at NC State and senior author of a paper on the research. “At any given time, the same person may want information on any of those things, so profiling the user isn’t necessarily very helpful.”

Anyanwu’s team has come up with a way to address the personalized search problem by looking at a user’s “ambient query context,” meaning they look at a user’s most recent searches to help interpret the current search. Specifically, they look beyond the words used in a search to associated concepts to determine the context of a search. So, if a user’s previous search contained the word “conservation” it would be associated with concepts likes “animals” or “wildlife” and even “zoos.” Then, a subsequent search for “jaguar speed” would push results about the jungle cat higher up in the results – and not the automobile or supercomputer. And the more recently a concept has been associated with a search, the more weight it is given when ranking results of a new search.

Search engines have also tried to identify patterns in user clicking behavior on search results to identify the most probable user intent for a search. However, such techniques are impersonal and are applied on a global basis. So, if the most frequent click pattern for a set of keywords is in a particular context, then that context becomes the context associated with queries for most or all users – even if your recent search history indicates that your query context is about jungle cats.

“What we are doing is different,” Anyanwu says. “We are identifying the context of search terms for individual users in real time and using that to determine a user’s intention for a specific query at a specific time. This allows us to deal more effectively with more complex searches than traditional search engines. Such searches are becoming more prevalent as people now use the Web as a key knowledge base supporting different types of tasks.”

While Anyanwu and her team developed a context-aware personalized search technique over a year ago, the challenge has been how to scale this approach up. “Because running an ambient context program for every user would take an enormous amount of computing resources, and that is not feasible,” Anyanwu says.

However, Anyanwu’s research team has now come up with a technique that includes new ways to represent data, new ways to index that data so that it can be accessed efficiently, and a new computing architecture for organizing those indexes. The new technique makes a significant difference.

“Our new indexing and search computing architecture allows us to support personalized search for about 2,900 concurrent users using an 8GB machine, whereas an earlier approach supported only 17 concurrent users. This makes the concept more practical, and moves us closer to the next generation of search engines,” Anyanwu says.

The paper, “Personalizing Search: A Case for Scaling Concurrency in Multi-Tenant Semantic Web Search Systems,” will be presented at the 2013 IEEE International Conference on Big Data being held Oct. 6-9 in Santa Clara, Calif. Lead author of the paper is Dr. Haizhou Fu, a former Ph.D. student at NC State. The paper was co-authored by Hyeongsik Kim, a Ph.D. student at NC State. The research was supported by the National Science Foundation.

On the Net:

Fragile X Syndrome Protein Linked To Breast Cancer Progression

Claudia Bagni (VIB/KU Leuven, Belgium, and the University of Rome Tor Vergata, Italy), has identified the way Fragile X Mental Retardation Protein or FMRP contributes to the progression of breast cancer. For this research the group of Bagni collaborated with colleagues from the VIB/KU Leuven departments of Bart De Strooper and Peter Carmeliet (VIB/KU Leuven), with Patrick Neven (UZ Leuven) and with several research centers and Hospitals in Italy and the UK. The researchers demonstrated that FMRP acts as a master switch controlling the levels of several proteins involved in different stages of aggressive breast cancer, including the invasion of cancer cells into blood vessels and the spread of these cancer cells to other tissues forming metastasis. The work is published on-line in EMBO Molecular Medicine.

Claudia Bagni: “Breast cancer is the most common form of cancer in women. It often comes back years after treatment and spreads throughout the body. We here show a correlation between the FMRP level in breast tissue and the chance of the spread of cancer to other organs. I hope that we can use this knowledge to develop a test to predict the likelihood of metastasis.”

The authors identified high levels of FMRP in human breast cancer tissue microarrays and also examined the effects of FMRP levels in a mouse model to study breast cancer. In these mice, high levels of FMRP in primary breast cancer tumors were also linked to the spread of the cancer to the lungs and the development of metastasis. Importantly, reduction of FMRP, on the contrary lead to a decrease of metastasis formation and protection against breast cancer in individuals lacking this protein.

The role of FMRP is well known in the brain, where its absence leads to Fragile X Syn-drome, the most prevalent form of inherited intellectual disability in humans. The present study explored the direct relationship between the levels of FMRP and the progression of breast cancer.

“Previous studies indicated that patients with Fragile X Syndrome had a decreased risk of developing cancer but little is known about the molecular events that lead to this beneficial effect. We showed that high levels of the FMRP protein in human breast tissue samples are linked to increased risk of breast cancer and the spread of the disease to other tissues throughout the body,” EMBO Member Claudia Bagni from VIB/KU Leuven, Belgium/ University of Rome Tor Vergata, Italy, who led the study, remarked. “Our results suggest that FMRP acts as a master regulator of a large group of mRNAs that are involved in multiple steps of cancer progression”.

The researchers suggest that the levels of FMRP might be used as an indicator of aggressive breast cancer and could be used to predict the likelihood of the spread of cancer to other organs like the lung. In fact, the authors found that FMRP levels correlate with the highly aggressive Triple Negative Breast Cancer. Breast cancer is the most common form of cancer in women and has a poor prognosis. It often comes back years after treatment and spreads throughout the body.

On the Net:

Midwest Cities Top List For Worst Allergies

[ Watch the Video: Is Your City High On The Allergy List? ]

Brett Smith for redOrbit.com – Your Universe Online

From Baton Rouge, Louisiana to Dayton, Ohio – the Midwest US appears to be the worst place for fall allergies this year, according to a new list from the Asthma and Allergy Foundation of America (AAFA).

The list ranked Wichita, Kansas as the No. 1 worst city for fall allergies in 2013, followed by Jackson, Mississippi and Knoxville, Tennessee.

To create the list, the foundation looked at the 100 most populous, concentrated metropolitan  areas in the continental US. Rankings were based on pollen counts, number of allergy drugs used per patient, and the number of board-certified allergists per patient. The report was sponsored by the prescription allergy nasal spray Dymista.

The top of the list is dominated by cities that are “places where ragweed thrives,” Mike Tringale, vice president of external affairs at AAFA, told USA Today. “In addition, there is some crossover — some grasses are still pollinating.”

The AAFA said the main allergy trigger this fall is expected to be ragweed pollen. It also said outdoor mold will be a problem because it continues to proliferate and will easily spread via fall weather and wind patterns.

This year’s list also showed a couple of cities dramatically changing in rank. Dallas jumped from No. 26 in 2012 to No. 18 this year, while Detroit dropped from place 10 to 19.

“Ragweed grows in urban areas, such as in cracks in sidewalks, along sides of roads and on roofs of buildings,” Tringale said. “AAFA encourages the approximately 40 million Americans who suffer from seasonal allergies to learn more and consult an allergy specialist for proper diagnosis and treatment of seasonal allergy symptoms.”

Ragweed is a highly invasive and prolific species. It is able to produce about a billion grains of pollen over a season, according to previous studies. Starting in early July in the Northern Hemisphere, the plants will bloom until mid-August or when cooler weather arrives.

The report also cited climate factors that could have an impact on the fall allergy season.

“Recent studies suggest that rising temperatures and carbon dioxide levels could be extending ragweed season by as much as a month or more,” a statement on the AAFA said. “This is especially true in the northern states in the US where there are now longer periods of warm weather than before.”

“Although the season has gotten off to a late start, with an above-average hurricane season predicted in the East and tornadoes expected in the Midwest, high winds from these weather patterns can cause increases in pollen distribution, leading to an increase in allergy symptoms,” the statement continued.

Tringale said the list isn’t intended to send people packing their bags.

“Don’t move; improve,” he suggested. “Improve your understanding of your diagnosis and your treatment. Improve your knowledge about how to avoid allergy triggers and reduce allergens in your home.”

“Allergies are bad everywhere,” Michael Kaliner, medical director of the Institute for Asthma and Allergy, told the national daily paper. “If allergies are left untreated or treated with the wrong medication, it can cause some serious complications.”

30-Minute Exercise More Effective Against Obesity Than Intense 1-Hour Workout

Michael Harper for redOrbit.com – Your Universe Online
Health officials fighting the “battle of the bulge” against obesity just got some good news. According to new research, 30 minutes of light, daily exercise can help someone shed more pounds than an hour of intensive training.
Additionally, those who committed to 30 minutes of daily exercise reported having higher levels of energy and more motivation to take the small steps necessary to lose the weight. The researchers at the University of Copenhagen who conducted the study say this could go a long way in battling the extremely harmful side effects of obesity.
Their study is now published in the Scandinavian Journal of Public Health.
“Obesity is a complex social problem requiring a multidisciplinary approach,” said Professor Bente Stallknecht from the Department of Biomedical Sciences at the Faculty of Health and Medical Sciences, University of Copenhagen in a statement.
“In a new scientific article we combine data from biomedical studies of the subjects’ bodies with ethnological data on their experiences during the 13-week trial period.”
Following this trial the test subjects were given qualitative interviews to understand on a deeper level how this exercise regimen affected their lives. Professor Stallknecht and PhD student Anne Sofie Gram recruited over 60 slightly overweight but otherwise healthy men to take part in this study. Some of these men were asked to simply exercise for a full 30 minutes every day. A second group of men were asked to undertake a one-hour, strenuous training regime every day.
Following the three month study, the men who exercised for just 30 minutes a day lost, on average, 7.94 pounds. By contrast, those men who exercised twice as long and twice as hard lost an average of 5.95 pounds at the end of the experiment.
The hard data shows a preference towards what the researchers call “light weight” 30-minute exercises. Yet they weren’t only interested in solid figures and also wanted to understand how this kind of exercise program affected the men on different levels, including culturally, emotionally and psychologically.
“The qualitative data offer a possible explanation for the surprising biological data,” says Astrid Jespersen, an ethnologist and associate professor at the University of Copenhagen.
“The subjects in the test group that exercised the least talk about increased energy levels and a higher motivation for exercising and pursuing a healthy everyday life. They take the stairs, take the dog for an extra walk or cycle to work. In contrast, the men who exercised for one hour a day, after training, felt exhausted, demotivated and less open to making a healthy change. We are thus seeing that a moderate amount of exercise will significantly impact the subjects’ daily practices.”
Jespersen’s desire to understand the multi-faceted effects of obesity don’t stop at simple exercise. The professor also says the issue of obesity must be tackled at many points by creating a holistic approach to the problem.
This isn’t the first time research has shown that even the littlest steps can go a long way in fighting obesity and staying healthy. An April report by the American Heart Association (AHA) showed that a brisk walk was just as effective as running.

Rhythm Closely Linked To Language In Brain

[ Watch the Video: Rhythm And Reading Go Hand In Hand ]

Brett Smith for redOrbit.com – Your Universe Online

Researchers at Northwestern University have found that people who can keep a beat are more responsive to speech neurologically than those with less rhythm, according to a report published in this week’s Journal of Neuroscience.

Study author Nina Kraus, a professor at Northwestern University and head of the Auditory Neuroscience Laboratory, pointed out that previous research has already made a connection between reading aptitude and neural response consistency. The researchers said their findings could mean that musical training might be useful in sharpening the brain’s response to language.

“By directly linking auditory responses with beat-keeping ability, we have closed the triangle,” said Kraus, describing the connection between brain activity, music and language.

Because hearing speech and associating specific parts of it with written words is important in learning how to read, the Northwestern neuroscientists said that the link between reading and beat keeping likely has a common foundation in the auditory system.

In the study, the Northwestern team recruited over 120 local Chicago high school students and gave them two tests. For the first test, the participants were asked to listen to a steady beat and tap their finger along to it on a pad that registered how closely their touches synced to the beat.

For the second test, the researchers used a technique called electroencephalography (EEG) to record the consistency of participants’ brain response to a repeated syllable – “da.”

“Across this population of adolescents, the more accurate they were at tapping along to the beat, the more consistent their brains’ response to the ‘da’ syllable was,” Kraus said.

“This is supported biologically,” she continued. “The brainwaves we measured originate from a biological hub of auditory processing with reciprocal connections with the motor-movement centers. An activity that requires coordination of hearing and movement is likely to rely on solid and accurate communication across brain regions.”

“Rhythm is an integral part of both music and language,” Kraus explained. “And the rhythm of spoken language is a crucial cue to understanding.”

For example, comprehensible speech requires changes in talking speed or emphasis. Subtle timing differences, such as the difference between making the “b” and “p” sounds, can make for significant differences in meaning. Also, hearing these distinctions is necessary to connect the sounds with the letters that they represent.

“Musicians have highly consistent auditory-neural responses,” Kraus said. “It may be that musical training – with its emphasis on rhythmic skills – can exercise the auditory-system, leading to less neural jitter and stronger sound-to-meaning associations that are so essential to learning to read.”

John Iversen, a cognitive neuroscientist at the University of California, San Diego who was not involved with this study, raised the possibility that musical training could have important impacts on the brain, based on the Northwestern team’s results.

“This study adds another piece to the puzzle in the emerging story suggesting that musical rhythmic abilities are correlated with improved performance in non-music areas, particularly language,” he said.

Kraus is currently performing a longitudinal study that examines the effects of music training by beat-keeping ability, neural response consistency, reading and other language skills in children as they receive music instruction year after year.

Rescue Device Can Locate Human Heartbeat In A Pile Of Rubble

[ Watch the Video: NASA Tech Will Hunt For Heartbeats After Disasters ]

Michael Harper for redOrbit.com – Your Universe Online

NASA, in partnership with the Department of Homeland Security (DHS), has developed a new technology which can detect heartbeats behind 20 feet of solid concrete or 30 feet of crushed material. This radar-based technology will be used in emergency situations where victims are trapped beneath collapsed buildings and other rubble.

The government agencies have been testing prototypes of this device for the last several months, and now they expect the first commercialized model of the product to be available by spring of 2014. Recent improvements in the design include a lightweight core, USB antenna and increased battery life of up to 14 hours.

NASA scientists at the Jet Propulsion Laboratory (JPL) in Pasadena, California, along with Science and Technology Directorate from the DHS, are calling this device ‘Finding Individuals for Disaster and Emergency Response,’ or FINDER. So far they’ve tested the unit in more than 65 simulated disasters with two Urban Search and Rescue Teams: The Virginia Task Force 1 at the Fairfax County Fire Department training center, and the Virginia Task Force 2 in Virginia Beach, Va.

Their goal was to create a tool that these teams could use to find signs of life in catastrophic situations. With this technology, lives could be saved which may have been lost forever underneath the rubble created by a tornado, earthquake or hurricane. The portable radar was able to penetrate concrete, rebar and other materials to distinguish heartbeats several feet away. When out in the open, the unit can detect a human heartbeat up to 100 feet away.

“Testing proved successful in locating a task force member buried in 30 feet of mixed concrete, rebar and gravel rubble from a distance of over 30 feet,” said DHS Science and Technology program manager John Price in a statement.

“This capability will complement the current urban search and rescue tools such as canines, listening devices and video cameras to detect the presence of living victims in rubble.”

The duo of the DHS and JPL seems to be a good fit in more ways than one. Edward Chow, JPL program manager, said the crushed and mangled material of a disaster presented some challenges for early prototypes of the device. Radar waves shot into the wreckage would bounce around and return irregular signals and, therefore, inaccurate results.

“Isolating the relatively weak signal of a heartbeat within the noisy signals becomes a difficult task,” said Chow. “JPL’s radar expertise helps in this challenge.”

The microwave radar technology isn’t just sensitive enough to distinguish the faint movement and sound of a heartbeat. It’s also smart enough to know if it’s “hearing” a human heartbeat or the heartbeat of some other living thing, such as a rat. These processing systems allow search and rescue operators to quickly understand if any survivors are trapped underneath slabs of concrete and debris and allow them to begin the process of extracting them.

After thorough testing of the earliest prototype, the DHS and JPL team decided to make a few changes to the design to improve the overall functionality of the device. One unit can perform all these tasks, including powering an antenna, a radar unit and digital processing, all with a single USB interface. The team also decided to change the user interface to make it easier to use by search and rescue teams. Future iterations of this device are expected to be even smaller and therefore easier to bring into disaster areas.

The DHS and JPL will demonstrate this new unit at a presentation next Wednesday in Virgina.

NASA: There Really Is No ‘Dark Side Of The Moon’

[ Watch the Video: Moon’s Dark Side Doesn’t Exist ]

Brett Smith for redOrbit.com – Your Universe Online

A newly released NASA video reminds us that there is no such thing as a dark side of the moon – just a far side.

Created from a patchwork of images taken by the Lunar Reconnaissance Orbiter (LRO), the video shows a 360-degree rotation of a fully-illuminated moon.

“It shows every surface of the moon being full,” NASA lunar geologist Noah Petro told the New York Daily News. “It’s a physically impossible view of the moon but it’s wonderful.”

[ Watch the Video: Rotating Moon From LRO ]

“Let’s imagine that the sun is directly overhead the entire moon,” Petro explained. “For every point on the lunar surface, how bright would it be if the sun were directly overhead?”

The video is just one result of the four years the LRO has spent circling the moon. The images of the lunar surface used for the video were taken with the probe’s Wide Angle Camera (WAC), which has a very wide field-of-view. The field-of-view allowed NASA scientists to create a near-global topographic map of the Moon, 360 degrees of longitude and 80 degrees north to 80 degrees south of latitude.

The wide field-of-view also created challenges for patching together the images and recreating lunar colors. Because the various perspective changes from the center to the edges of each image’s frame, the perceived reflectance of the Moon shifts as the camera angle changes. In images captured by the WAC, the lunar surface looks most reflective in the center of the image. This effect causes in a pole-to-pole striped image when making an uncorrected image mosaic.

To fix this effect, scientists took 36 nearly complete global mosaics, comprised of 110,000 WAC images, and determined an equation that included Sun angle and view angle result with respect to reflectance changes. This equation was applied to each pixel in those 110,000 WAC images to adjust the measured brightness everywhere on the Moon.

All those calculations allowed for the creation of a crystal clear view of the so-called dark side of the moon. This side of the moon actually receives sunlight on a daily basis. However, because the moon’s rotation syncs perfectly with its orbit around the Earth – we never get to see the moon’s far side.

“The only way we can see the far side of the moon is with a spacecraft,” said Petro. “The important part of the video shows that there is no dark side of the moon — there’s a far side.”

Topographical variations on the moon are difficult to see in the video, but differences in albedo – relative reflectance – are enhanced. The moon’s craters only get limited sunlight and appear darker than the surrounding areas.

The LRO has been orbiting the moon since 2009, gathering terabytes of data on the lunar surface. In addition to creating the newly released mosaic video, the LRO mission has also created the most detailed topography map of the moon.

The LRO has also been used to test a new laser-based, deep-space communication system. In January, NASA successfully transmitted an image of the Mona Lisa from the Goddard Space Flight Center in Greenbelt, Md. to the LRO using the system.

Structure Of The Brain May Predispose You To Chronic Pain

[ Watch the Video: Pain in the Brain with Dr. Vania Apkarian ]
Brett Smith for redOrbit.com – Your Universe Online
By using brain scans on chronic pain sufferers, neuroscientists based in Chicago have discovered a connection between the brain and experiencing chronic pain, according to a report in the journal Pain.
“We may have found an anatomical marker for chronic pain in the brain,” said study author Vania Apkarian, a professor of physiology at Northwestern University Feinberg School of Medicine.
About 23 percent of individuals with low back pain are chronic, or long-term, sufferers. While some sources of pain can be seen at the site of injury, recent research indicates that the brain may be more involved with chronic pain than previously thought.
“Currently we know very little about why some patients suffer chronic low back pain,” said Dr. Debra Babcock, a program director at the National Institute of Neurological Disorders and Stroke (NINDS). “The earlier we detect pain will become chronic, the better we may be able to treat patients.”
The research team began by scanning the brains of 46 volunteers who reported low back pain for about three months before coming to a hospital for treatment, but who had not experienced any pain for at least a year before onset.
The researchers scanned the subjects’ brains and evaluated their pain four times over the course of one year. About half of the subjects recovered at some point during the course of the study, while the other half reported persistent pain throughout.
A scanning technique used by the researchers called diffusion tensor imaging (DTI) measured the structure of participants’ white matter, or the nerve cells, which connect brain cells in different regions of the brain. The team was able to discover a marked difference in white matter between the subjects who recovered from chronic pain and those who felt pain throughout the year.
“Our results suggest that the structure of a person’s brain may predispose one to chronic pain,” Apkarian said.
The scientists also found that the white matter of subjects with persistent pain resembled a third group of subjects that reported chronic pain. Additionally, the white matter of participants who recovered resembled that of healthy control subjects.
To expand on their findings the researchers looked to see if the white matter differences predicted whether the subjects would recover from or continue to experience pain. They discovered that white matter brain images predicted more than 80 percent of the outcomes.
“We were surprised how robust the results were and amazed at how well the brain scans predicted persistence of low back pain,” Apkarian said. “Prediction is the name of the game for treating chronic pain.”
The researchers identified the nucleus accumbens and the medial prefrontal cortex as two brain structures most likely involved with pain. They added that the brain scans indicate structural differences in the white matter linking these brains regions between the subjects who recovered and those who reported persistent pain.
“Our results support the notion that certain brain networks are involved with chronic pain,” Apkarian said. “Understanding these networks will help us diagnose chronic pain better and develop more precise treatments.”

Red Meat-Eating Neanderthals May Have Also Been Fish Eaters

Brett Smith for redOrbit.com – Your Universe Online

Scientists have theorized that the reason Homo sapiens were able to out-compete Neanderthals was because they embraced a more diverse diet. However, new evidence being presented by a group of European scientists indicates that Neanderthal menus may have been more diverse than previously thought.

According to a study published recently in the journal Quaternary International, salmon bones found in a cave in the Caucasus Mountains were left there by Neanderthals – meaning our prehistoric competition enjoyed fish as a part of their diet.

A prevailing theory posits that Neanderthals stuck to a strict diet of mostly large herbivorous mammals, such as woolly mammoths and wild bison. Meanwhile, our ancestors were said to have been better equipped to a changing ecosystem by incorporating a more diverse range of food into their diets.

The new study is based on animal bones found in caves occupied by these two types of prehistoric hominids. It would be easy to automatically attribute the salmon remains to Neanderthals and Homo sapiens, but scientists needed to exclude other large predators, such as bears or cave lions, which would have lived in the area at the same time.

In a cave on the northern slopes of the Caucasus Mountains, scientists discovered bone fragments of large salmon that were most likely caught as they migrated from marine waters to their freshwater spawning places. The fishy remains were found in the Middle Palaeolithic archaeological layers, dated to between 42,000 and 48,000 years ago. Study researchers said they suspect Neanderthals left the remains, but remains of Asiatic cave bears (Ursus kudarensis) and cave lions (Panthera spelaea) were also found in the cave and could have preyed on the large meaty fish.

To determine who the salmon predators were, the bear and lion remains were evaluated using carbon, nitrogen and sulfur isotopes found in bone collagen; the isotopic signatures were compared between predators and their potential prey.

The comparison revealed that salmon was neither eaten by the cave bears, which were purely vegetarian, nor cave lions.

“This study provides indirect support to the idea that Middle Palaeolithic Hominins, probably Neandertals, were able to consume fish when it was available, and that therefore, the prey choice of Neandertals and modern humans was not fundamentally different,” said study author Hervé Bocherens, a biogeologist at Universität Tübingen, in Germany.

Bocherens said more than diet differences caused the demise of the Neanderthals.

Neanderthals appear to be gaining respect from the scientific community by leaps and bounds as a study published in August indicated that groups of the prehistoric humanoids had unique cultural differences. Based on stone tool differences, researchers from the University of Southampton asserted that a more complex Neanderthal culture existed than what experts had previously thought.

“In Germany and France there appears to be two separate handaxe traditions, with clear boundaries, indicating completely separate, independent developments,” said study author Karen Rubens. “The transition zone in Belgium and Northern France indicates contact between the different groups of Neanderthals, which is generally difficult to identify but has been much talked about, especially in relation to later contacts with groups of modern humans.”

Whale Earwax Reveals Secrets Of Their Past

[ Watch the Video: Blue Whale Earwax Tells A Tale Of A Lifetime ]

Brett Smith for redOrbit.com – Your Universe Online

Earplugs made of wax and fats are common to blue and other large whales and resemble the waxy buildup in our own ears – except on a much, much larger scale.

To learn more about the history of individual whales, marine biologists from Baylor University and the Natural Museum of History have developed a unique method for analyzing these earplugs. The technique reveals a whale’s chronological hormone levels and exposure to chemicals, according to a new report in Proceedings of the National Academy of Sciences of the United States of America.

“Scientists in the past have used this waxy matrix as an aging tool, similar to counting tree rings,” said Sascha Usenko, assistant professor of environmental science at Baylor. “Then, the question arose: Could whale earwax chronologically archive chemicals, such as man-made pollutants?”

Over the past two years, Usenko and his colleague Steven Trumble have been working to answer just that question.

“The type of information we can derive from these earplugs along with our methodology is exceptionally valuable,” Usenko said. “There is nothing like it. It really should be classified as a new field of research.”

Previous studies have looked at whale blubber to establish a whale’s hormone and chemical exposure. However, those studies have only yielded information on limited periods of time. Moreover, these results were difficult to obtain and cost-prohibitive.

“Whales are free-ranging animals and you can’t get these types of profiles or information on free-ranging animals in any part of the world,” said Trumble, an assistant professor of biology at Baylor. “This has never been done before.”

With their novel method, the Baylor researchers said they can also see the human impact on individual whales across multiple generations and various ecosystems.

“You have this 100-year-old question: How are we impacting these animals? There is ship traffic, environmental noise, climate change and contaminants. Now, we are able to provide definitive answers by analyzing whale earwax plugs,” Usenko said.

Besides determining human impact on these whales, the scientists were also able to find out information about specific hormonal events that occur during a whale’s lifetime.

“Our research was able to improve upon estimates of sexual maturity for blue whales,” Trumble said. “Previous estimates provided a 10-year range of maturity and we have been able to pinpoint exactly when the whale in the study hit sexual maturity. Our research was able to shed new light on the life cycle of whales.”

Usenko added that their newly developed technique could be used on historical samples to gain a better understanding of whales and human-whale interactions over time.

“We are able to go back in time and analyze archived museum earplug samples that were harvested in the 1950s and examine critical issues such as the effects of pollution, use of sonar in the oceans and the introduction of specific chemicals and pesticides in the environment over long periods of time,” Usenko said.

“There are a myriad of ways that we can analyze plugs for a better understanding of marine ecosystems and these endangered animals. There is so much additional information that can be mined from studying earplugs.”

Researchers May Have Solved The Spin Mystery Of Earth’s Core

April Flowers for redOrbit.com – Your Universe Online

For the last 300 years at least, we have been questioning what direction the center of the earth spins. A group of scientists from the University of Leeds, UK, and the Swiss Federal Institute of Technology may have found the answer.

According to the study, published in Proceedings of the National Academy of Sciences (PNAS), the Earth’s inner core – made of solid iron – “superrotates” in eastward directions. This means it spins faster than the rest of the planet. Made of mostly molten iron, the outer core spins westward at a slower pace.

Edmund Halley, who discovered Halley’s comet, revealed the westward drifting motion of the planet’s geomagnetic field in 1692. The current study is the first time that scientists have been able to link the way the inner core spins to the behavior of the outer core. The researchers say the Earth behaves this way because it is responding to the geomagnetic field. They hope their findings will enable scientists to interpret the dynamics of the core of the Earth, the source of our planet’s magnetic field.

Relative to the Earth’s surface, seismometers measuring earthquakes as they travel through the Earth’s core have identified an eastward direction of the solid inner core for the last few decades.

“The link is simply explained in terms of equal and opposite action”, explains Dr Philip Livermore, of the School of Earth and Environment at the University of Leeds. “The magnetic field pushes eastwards on the inner core, causing it to spin faster than the Earth, but it also pushes in the opposite direction in the liquid outer core, which creates a westward motion.”

About the size of the Moon, the solid inner core is surrounded by the liquid outer core. This outer core is an iron alloy, whose convection-driven movement generates the geomagnetic field.

Scientists know that the planet’s internal magnetic field changes slowly over a timescale of decades. This means that the electromagnetic force responsible for pushing the inner and outer cores will itself change over time, and may explain fluctuations in the predominantly eastward rotation of the inner core. These fluctuations were reported for the last 50 years by Tkalčić et al. and recently published in Nature Geoscience.

Based on archeological artifacts and rocks – with ages of hundreds to thousands of years, additional prior studies have suggested that the drift direction has not always been westward. Evidence suggests that some periods of eastward motion may have occurred in the last 3,000 years. When this data is viewed within the conclusions of the new model, it suggests that the inner core may have undergone a westward rotation in such periods.

The Leeds team used the giant super computer Monte Rosa, which is part of the Swiss National Supercomputing Centre in Lugano, Switzerland, to run the model of the Earth’s core. A new method allowed them to simulate the Earth’s core with an accuracy 100 times better than previous models.

Blame Your Cold Sore On A Genetic Mutation, Scientists Say

Lee Rannals for redOrbit.com – Your Universe Online

Ever feel a little embarrassed when a cold sore flare up comes around because you’ve been told its herpes? Well, rest-easy friend because scientists are giving you a much more socially-acceptable excuse by blaming it on a genetic mutation.

About one in five people feel the embarrassment that comes with a cold sore infection, and scientists have had a hard time determining why some people are more prone to the virus than others. However, researchers at the University of Edinburgh wrote in the journal PLOS Pathogens that they have found the link.

Although only 20 percent of people experience the herpes simplex virus type 1 flare-ups, between 80 and 90 percent of people are infected with the virus. The researchers analyzed thousands of genes in order to determine why.

The team set out to look for genes that expressed the proteins needed by the body’s immune system to prevent the virus from becoming active and cold sores from developing. They also looked at blood samples from people with cold sores and found that one of the genes previously identified was mutated.

This mutation means that the body was not able to mount an adequate immune response to the virus, which results in cold sores. The gene, known as IL28b, is also linked to treatment responses for hepatitis C patients.

Researchers say that if this gene is mutated in hepatitis C patients, then they are less likely to respond as well to treatment. The link is further evidence that a single genetic mutation can be linked to different viruses.

“Most people carry the cold sore strain of the herpes simplex virus, but until now we never knew why only some of them develop cold sores,” said Professor Juergen Haas, of the University of Edinburgh’s Division of Pathway Medicine. “Knowing that susceptibility to the virus involved relates to people’s genes reinforces the need to research, not only the evolution of viruses themselves, but also the susceptibility of hosts to infection.”

Researchers from Columbia University and the University of Miami have given even more reason to find a cure for cold sores after finding that the virus can cause cognitive difficulties. According to the research published in the journal Neurology in March, individuals who have been regularly exposed to herpes simplex type 1 over the years were more likely to have trouble performing cognitive tests than people with histories of low infection levels.

New Study Shows How ‘Technovigilance’ Can Help Save Lives In Hospitals

University of Leicester

Electronic data routinely gathered in hospitals can be used as a warning system for missed doses of prescribed medicine and making improvements to patient safety, says a new study.

A team from the Universities of Leicester and Birmingham found that the secondary use of data from an electronic prescribing and decision support system in an English hospital led to a ‘substantial and sustained’ reduction in rates of missed or delayed doses of medicines.

Published in the world-leading health policy journal Milbank Quarterly, the study looked at how using the electronic system combined with organizational efforts helped to address a major patient safety threat.

Roughly one in five patients in NHS hospitals miss a dose of prescribed medication or get it late. The National Patient Safety Agency has shown that omitted or delayed doses of essential drugs are a major problem, responsible for 27 deaths, 68 severe injuries and 21,283 patient safety incidents between 2006 and 2009 in the UK. But effective solutions for monitoring and reducing the problem have been hard to find.

The electronic system in the study hospital could be programmed to trigger a series of emails if, for example, a patient missed more than two doses of antibiotics. If no action was taken, these emails was be escalated upward, from ward nurse through the layers of the hospital, eventually to chief executive.

Professor Mary Dixon-Woods, Professor of Medical Sociology at the University of Leicester Department of Health Sciences, says: “This is one element of what we call ‘technovigilance’ – turning data into intelligence which can then be put into effective action. Other elements include using the electronic system to find examples of where care did not seem to meet the required standards, and holding high-level care omissions meetings with staff on clinical areas to find out what happened”.

‘Technovigilance’ was credited with a fall in the rate of missed doses from 12% to 5%.

Dr Jamie Coleman of the University of Birmingham commented that: “Data generated by the system is used to make formerly hard-to-detect practices, behaviours and performance more transparent. This means necessary preventative action can be taken more easily.”

The study found that these preventative actions included fixing organizational systems – such as delivery of medicines to specific locations – as well as emphasizing the personal responsibility of individual staff. The hospital’s executive team credited technovigilance with a major “cultural shift” in staff attitudes towards administering medicines on time.

In an accompanying editorial, Professor David Bates of Harvard University comments that, “Such data can have a powerful effect on improvement. But in the rush to computerize, tools like this are not yet a routine component of most electronic health records. The overall implication is that all hospitals will need tools like this, and soon.”

But technovigilance was not without its unintended consequences.

Dr Coleman says: “Technovigilance is intentionally used as a way of ensuring that individuals know their behaviour is being monitored and that they will be open to scrutiny. Although it’s not strictly intended to be punitive, being called to a care omissions meeting, for instance, could be a very uncomfortable experience for staff.”

Other unintended consequences found in the study included the risk that staff focused on the things being measured at the expense of other less measurable but important activities, or ‘gaming’, where staff may try to create the appearance of better performance.

Professor Dixon-Woods commented: “One danger was that staff were so busy doing things that were going to be electronically monitored by the system that they did not have time to do other equally valuable things – such as talking to patients. We also identified concerns that the way the system was set up meant that nurses’ behaviour was subject to much more surveillance than others.”

The model of technovigilance is now being optimized in light of findings from the study. The researchers stress that using alternative and complementary forms of intelligence, including evidence of patients’ experience and executive visits to clinical areas, may be important in countering the distorting effects of technovigilance and allowing a more complete picture of the quality and safety of patient care to emerge.

On The Net:

Even The Experts Are Afraid Of Spiders

[ Watch the Video: Entomologists With Arachnophobia? ]

Brett Smith for redOrbit.com – Your Universe Online

Arachnophobia, or the fear of spiders, is understandable in the typical person. However, University of California, Riverside professor Richard Vetter recently looked into the prevalence of this phobia in entomologists – men and women who work with bugs on a daily basis.

According to a report of Vetter’s study published in American Entomologist, a survey of 41 self-described arachnophobic entomologists found that these folks react differently to spiders than to insects. Based on responses to a standardized Fear of Spiders Questionnaire (FSQ), some respondents scored as clinically arachnophobic and said they react to spiders in an almost debilitating manner.

Some of the arachnophobic entomologists said their fear developed in childhood, well before making the somewhat unusual choice of pursuing a career in entomology.

“The results of the study show that arachno-adverse entomologists share with arachnophobes in the general public both the development of response and the dislike of many of the behavioral, physical, and aesthetic aspects of spiders,” said Vetter, an entomologist himself.

“Paradoxically, I found that despite the great morphological diversity that insects exhibit and despite years of professional exposure to insects, these entomologists do not assimilate spiders into the broad arthropod morphological scheme,” he continued.

“However, for the most part these entomologists realized that their feelings could not be rationally explained. Through the mere existence of the study, several of them took solace in learning that they were not alone with their negative spider feelings.”

The article also revealed several amusing arachnophobia-related anecdotes, including some from respondents that regularly work with maggots and other unappealing creatures.

“I would rather pick up a handful of maggots than have to get close enough to a spider to kill it,” one respondent told Vetter.

“Maggots don’t sneak up on you and jump in your hair,” another replied.

Other respondents told Vetter of childhood incidents or experiences that may have contributed to their fear.

“One respondent had a recurring childhood nightmare (from age 4 to 8) of running around her house into the large web of a human-sized spider and waking up just before being eaten,” Vetter wrote in the article.

Another respondent blamed her sister for causing or increasing her arachnophobia by chasing her around the house with “dead spiders in tissues.”

One female respondent said she was tormented with spiders by her brother, but was able to exact a measure of retribution when she discovered that he was severely afraid of mushrooms.

In his conclusion, Vetter said the small survey reinforced previous findings on arachnophobia; namely, that it usually begins in childhood, appears to have something to do with familiar interactions with arachnids, and affects women more than men.

“Vetter’s study illustrates how the fear of spiders found in some entomologists may have roots in negative events that happened in childhood,” said Gene Kritksy, editor-in-chief of American Entomologist.

“This gives us insight on how to lessen this fear in future generations. If parents have a genuine interest in the natural world, including spiders, and they share this positive interest with their children, it could reduce the incidence of arachnophobia in the long run.”

Robot Snakes On Mars

[ Watch the Video: ESA Wants To Send A Robotic Snake To Mars ]

Lee Rannals for redOrbit.com – Your Universe Online

The European Space Agency (ESA) is looking into the idea of sending a snake to Mars in order to help scientists deepen their knowledge about the Red Planet.

Researchers are reportedly developing a snake-like robot that could be paired up with a rover to help future explorers investigate regions that are typically inaccessible. NASA’s Curiosity and Opportunity rovers have had great success helping scientists gather more data about Mars, but clunky wheels prevent the Martian vehicles from exploring nooks and crannies that may hide secrets about the Red Planet’s past. A more versatile snake robot could be the key in attempting to go where no rover has gone before.

“One option is to make the robot into one of the vehicle’s arms, with the ability to disconnect and reconnect itself, so that it can be lowered to the ground, where it can crawl about independently.”

Snake robots could help assist rovers in collecting samples to be returned back to Earth by getting into the tight spots rovers can’t reach. The researchers say the rover would help navigate over large distances, while the snake robot could detach itself and crawl into the tighter spaces. A cable would connect the robot to the vehicle to help provide power, communication and a winch for emergencies.

“We are looking at several alternatives to enable a rover and a robot to work together. Since the rover has a powerful energy source, it can provide the snake robot with power through a cable extending between the rover and the robot. If the robot had to use its own batteries, it would run out of power and we would lose it,” said Aksel Transeth from Norwegian robotics company SINTEF in a statement.

“The connection between the robot and the rover also means that the snake robot will be able to assist the vehicle if the latter gets stuck,” says Pål Liljebäck, another researcher on the project. “In such a situation, the robot could lower itself to the ground and coil itself around a rock enabling the rover to pull itself loose by means of the cable winch, which the rover would normally use to pull the snake robot towards the rover”.

ESA hired SINTEF to carry out research on how this snake robot-rover relationship could potentially work. The space agency has a new Mars mission planned for 2018 called ExoMars. This rover will be exploring the Martian surface to search for evidence of microbial life, and will be equipped to drill to a depth of six feet and collect samples that have been shielded from the harsh conditions on the surface.

Achilles’ Heel Of Ice Shelves Is Beneath The Water

New research has revealed that more ice leaves Antarctica by melting from the underside of submerged ice shelves than was previously thought, accounting for as much as 90 per cent of ice loss in some areas.

Iceberg production and melting causes 2,800 cubic kilometers of ice to leave the Antarctic ice sheet every year. Most of this is replaced by snowfall but any imbalance contributes to a change in global sea level.

For many decades, experts have believed that the most important process responsible for this huge loss was iceberg calving – the breaking off of chunks of ice at the edge of a glacier.

New research, led by academics at the University of Bristol with colleagues at Utrecht University and the University of California, has used satellite and climate model data to prove that this sub-shelf melting has as large an impact as iceberg calving for Antarctica as a whole and for some areas is far more important.

The findings, published today [15 September] in Nature, are crucial for understanding how the ice sheet interacts with the rest of the climate system and particularly the ocean.

During the last decade, the Antarctic ice-sheet has been losing an increasing amount of its volume. The annual turnover of ice equates to 700 times the four cubic kilometers per year which makes up the entire domestic water supply for the UK.

Researchers found that, for some ice shelves, melting on its underbelly could account for as much as 90 per cent of the mass loss, while for others it was only 10 per cent.

Ice shelves which are thinning already were identified as losing most of their mass from this melting, a finding which will be a good indicator for which ice shelves may be particularly vulnerable to changes in ocean warming in the future.

The scientists used data from a suite of satellite and airborne missions to accurately measure the flow of the ice, its elevation and its thickness. These observations were combined with the output of a climate model for snowfall over the ice sheet.

They compared how much snow was falling on the surface and accumulating against how much ice was leaving the continent, entering the ocean and calving. By comparing these estimates, they were able to determine the proportion that was lost by each process.

Professor Jonathan Bamber, from the University of Bristol’s School of Geographical Sciences, said: “Understanding how the largest ice mass on the planet loses ice to the oceans is one of the most fundamental things we need to know for Antarctica. Until recently, we assumed that most of the ice was lost through icebergs.

“Now we realize that melting underneath the ice shelves by the ocean is equally important and for some places, far more important. This knowledge is crucial for understanding how the ice sheets interact now, and in the future, to changes in climate.”

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Was Life On Earth Jump-Started By Icy Comet Impact?

[ Watch the Video: Comets May Have Provided Earth The Building Blocks Of Life ]

Lawrence LeBlond for redOrbit.com – Your Universe Online

An international group of scientists has discovered that life on Earth may have been jump-started when icy comets bombarded the planet billions of years ago.

Scientists from University College London, the University of Kent and Lawrence Livermore National Laboratory have published a paper, appearing on the Nature Geosciences website on September 15. In this paper, the team describes how collisions between icy comets and rocky planets can jump start life.

First predicted in 2010 by LLNL chemist Nir Goldman, PhD, the evidence came to light after scientists shock compressed an icy mixture, which then created a number of amino acids — the building blocks of life.

This icy mixture is very similar to the composition of comets, indicating that the icy cosmic travelers have the correct elements needed to bring life to otherwise vacant rocky worlds. In such the same manner, rocky meteorites can bring life to icy worlds.

Goldman first posited that impact by icy comets billions of years ago provided the right elements to allow a variety of prebiotic compounds, such as amino acids, to jump start life on planet Earth. Amino Acids are critical to life, and Goldman’s work predicted that simple molecules found in comets containing water, ammonia, methanol and carbon dioxide, among others, could have supplied the materials needed to jump-start life. Once an impact occurred, the abundant supply of energy produced by the impact could have forced this prebiotic chemistry into overdrive.

The researchers in the latest study, which also includes Goldman, suggest that this process adds another chapter to the story of how life originated on planet Earth some 4.5 to 3.8 billion years ago when the planet was heavily bombarded by comets and meteorites.

“These results confirm our earlier predictions of impact synthesis of prebiotic material, where the impact itself can yield life-building compounds,” Goldman said. “Our work provides a realistic additional synthetic production pathway for the components of proteins in our Solar System, expanding the inventory of locations where life could potentially originate.”

Dr Zita Martins, coauthor from the Department of Earth Science and Engineering at Imperial College London, said, “Our work shows that the basic building blocks of life can be assembled anywhere in the Solar System and perhaps beyond. However, the catch is that these building blocks need the right conditions in order for life to flourish. Excitingly, our study widens the scope for where these important ingredients may be formed in the Solar System and adds another piece to the puzzle of how life on our planet took root.”

“This process demonstrates a very simple mechanism whereby we can go from a mix of simple molecules, such as water and carbon-dioxide ice, to a more complicated molecule, such as an amino acid. This is the first step towards life. The next step is to work out how to go from an amino acid to even more complex molecules such as proteins,” added Dr Mark Price, coauthor from University of Kent.

For the latest study, the collaborators conducted a series of experiments similar to Goldman’s previous experiments in which a projectile was fired into a typical cometary ice mixture at speeds of 4.25 miles per second. Upon impact, several different types of amino acids began forming.

It is known that comets do contain simple ice mixtures and organic precursors of amino acids. The most recent discovery was that of Glycine – one of the simplest amino acids – in the comet Wild-2.

The team noted that it is possible that similar events may occur or likely have occurred elsewhere in the Solar System; Saturn’s moons Europa and Enceladus contain a mix of simple organics and water ice. The team concluded that if a rocky meteorite impacted either of these moons with enough force, enough energy should be produced to promote shock synthesis of more complex organic compounds, including life-building amino acids.

“This increases the chances of life originating and being widespread throughout our Solar System,” Goldman said.

The team said this work underlines the importance of future space missions to these moons and other similar bodies to search for signs of life.

JAXA’s Laptop-Controlled Epsilon-1 Rocket Launched Saturday Morning

redOrbit Staff & Wire Reports – Your Universe Online

Following a two-week delay, the Japan Aerospace Exploration Agency (JAXA) successfully launched their new, reportedly less expensive Epsilon Launch Vehicle (Epsilon-1) early Saturday morning.

In a statement, JAXA officials confirmed that Epsilon-1, which was carrying the Spectroscopic Planet Observatory for Recognition of Interaction of Atmosphere (SPRINT-A) remote observation telescope, lifted off from the Uchinoura Space Center in Kagoshima at 2:00pm local time (0500 GMT/1:00am EDT).

“The launch vehicle flew smoothly, and, at about 61 minutes and 39 seconds after liftoff, the separation of the SPRINT-A was confirmed,” the agency said. “We would like to express our profound appreciation for the cooperation and support of all related personnel and organizations that helped contribute to the launch of the Epsilon-1.”

According to the AFP news agency, Saturday’s launch was coordinated and controlled by two laptop computers from a nearby command center, and drew spectators both at the Kagoshima facility and at a public viewing location in Tokyo.

The news agency reported that over 900 space enthusiasts gathered to watch the liftoff in the Japanese capital, clapping and snapping cellphone photos as the 24 meters (79 feet) long, 91 metric ton Epsilon-1 launched. The vehicle then successfully deployed SPRINT-A at an altitude of approximately 1,000 kilometers (620 miles).

A previous launch, which had been scheduled for August 27, had been aborted just 19 seconds before liftoff due to a computer glitch, the Associated Press (AP) reported. That glitch involved the erroneous reporting of a positional abnormality, and forced the Epsilon-1 launch to be postponed for a period of two weeks, AFP added.

“The successful launch moved Japan a step closer to its goal of cashing in on the international satellite launch industry,” Reuters reporter Leika Kihara explained. “The rocket’s smaller size and a computer system that allows it to perform its own systems checks means it can be assembled quickly, enabling operators to cut personnel and equipment costs.”

In fact, JAXA officials told the AP that the Epsilon – the nation’s first new rocket design since the introduction of the H2A in 2001 – costs about one-third as much as its predecessor, at 3.8 billion yen ($40 million). It is also half the size of the H2A, the wire service noted, and can be assembled and prepared for launch in just one week’s time.

“Japan hopes the rocket, launched with just two laptop computers in a pared-down command center, will become competitive in the global space business,” AFP noted. They also pointed out that a crew of just eight people are required to complete launch procedures, compared to a staff of 150 for the H2A.

“The small-sized rocket is equipped with artificial intelligence ‘for the first time in the world’ that allows autonomous launch checks by the rocket itself, JAXA has said,” the news agency continued, adding that the agency has described the SPINT-A payload it carries as “the world’s first space telescope for remote observation of planets including Venus, Mars and Jupiter from its orbit around Earth.”

Orange Juice Could One Day Help Prevent Cancer

redOrbit Staff & Wire Reports – Your Universe Online

Orange juice contains vitamin C and several other key nutrients, and has also been linked to a reduced risk of obesity in adults, but recently-published research suggests that it could also help prevent cancer.

In a review article that was published online last month in Nutrition and Cancer: An International Journal, a team of Brazilian experts presented evidence linking the popular fruit drink with cancer chemoprevention. They also discussed the putative mechanisms and potential adverse health effects associated with orange juice.

They found that orange juice (OJ) contained several potentially beneficial effects when it comes to battling cancer, especially due to its high antioxidant content from flavonoids such as hesperitin and naringinin. In addition, they said that evidence from earlier in vitro studies indicated that the beverage could reduce a child’s risk of developing leukemia, as well as aiding chemoprevention against mammary, hepatic, and colon cancers.

“OJ has antimicrobial and antiviral action and modulates the absorption of xenobiotics,” the authors explained in the study. “Therefore, OJ could contribute to chemoprevention at every stage of cancer initiation and progression. Among the most relevant biological effects of OJ is the juice’s antigenotoxic and antimutagenic potential, which was shown in cells in culture and in rodents and humans.”

“The biological effects of OJ in vitro were shown to be largely influenced by the juice’s composition,” they added. “The composition of OJ depends on physiological conditions (related to climate, soil and fruit maturation, the genetic characteristics (varietal) of the oranges and variations in processing methods and storage times and methods. The addition of sugars seems to substantially decrease the antioxidant effect of OJ. Thermal treatments, storage above 20°C or both can lead to an even greater decrease in antioxidant activity.”

The researchers warn that the in vitro effects of orange juice are influenced by the composition of the drink, which itself is dependent upon the conditions under which the fruit was grown – including the climate, the soil, the period of maturation and the post-harvest storage methods.

They also said that drinking too much of the beverage could be potentially toxic, especially in children, diabetics, people with hypertension and those with kidney problems. Excessive consumption of orange juice for any of these types of individuals could lead to noxious effects, hyperkalemia (elevated blood potassium levels), the development of food allergies, or bacterial contamination in instances where the drink was not pasteurized.

Study authors Silvia Isabel Rech Franke, Temenouga Nikolova Guechev, João Antonio Pêgas Henriques and Daniel Prá (who are affiliated with the Universidade de Santa Cruz do Sul, the Universidade Federal do Rio Grande do Sul, and the Universidade de Caxias do Sul) added that additional research was recommended in order to determine the actual biological link between orange juice and cancer chemoprevention.

CPAP Therapy Shown To Help Sleep Apnea Patients Get Their Beauty Sleep

redOrbit Staff & Wire Reports – Your Universe Online
Telling someone that you need your beauty sleep may not be just an expression anymore, as new research demonstrates that sleep apnea patients appear to be more attractive – as well as more alert and youthful – after receiving two months of treatment for the disorder.
Writing in the September 15 edition of the Journal of Clinical Sleep Medicine, Dr. Ronald Chervin of the University of Michigan Health System and colleagues reported that people suffering from obstructive sleep apnea (OSA) look better and sleep better after at least eight weeks of continuous positive airway pressure (CPAP) therapy.
“This study showed that independent human raters – both medical personnel and members of the community – can perceive improved alertness, attractiveness, and youthfulness in the appearance of sleepy patients with obstructive sleep apnea, after they have been compliant with use of CPAP at home,” Dr. Chervin said. “These results show that the subjective impression of many clinicians, namely that their patients look more alert and sometimes more youthful after treatment for obstructive sleep apnea, may well be something that can be perceived by many other people.”
The researchers recruited 20 adults who suffered from OSA and experienced excessive levels of daytime sleepiness. Each subject had a digital photo of his or her face taken with a high-precision 3D camera both before and after undergoing a minimum of two months’ worth of CPAP therapy.
The images were then analyzed side-by-side using computer software to assess the volume and color of the face. In addition, 22 volunteers (12 medical professionals and 10 community volunteers) were recruited to look at the two images together, in random order, and rate each in terms of alertness, youthfulness and attractiveness.
Of the 20 subjects, an average of 68 percent of evaluators identified the post-treatment facial images as having a more alert appearance than the pre-CPAP picture. Furthermore, 67 percent selected the post-treatment photo as being more attractive, and 64 percent said that it was more youthful in appearance. Image analysis also found post-treatment decreases in forehead surface volume and decreased redness under the eyes.
However, Chervin and his colleagues said that they did not detect overly noticeable changes in other types of facial characteristics often associated with sleepiness. The post-treatment images did not document any improvement in a person’s tendency to have dark blue circles or puffiness under the eyes, they added, indicating that additional research was required to assess facial changes in a greater number of patients over a longer period of treatment.
Image 2 (below): These images are labeled to show which was taken before the patient had CPAP treatment for sleep apnea, and which was taken after. In the study, independent raters who didn’t know which was which were able to tell the difference two-thirds of the time. A detailed analysis of these and other images also showed less redness and forehead puffiness after treatment — though no improvement in dark circles or puffiness under the eyes. Credit: University of Michigan Health System

Could Life On An Asteroid Survive Impact With Earth?

John P. Millis, PhD for redOrbit.com – Your Universe Online

Where did life come from? It is a fundamental question that has consumed scientific inquiry for centuries. And naturally, theories abound. While some believe that life as we know it arose naturally from Earth, others believe that if may have come from outer space.

It sounds almost like something out of science fiction, but panspermia – the theory that life can naturally transplant from one from planet, comet, or asteroid, to another – remains a serious scientific position. The challenge is that it is difficult to prove or disprove. In fact, it has been difficult to demonstrate that it is even possible, much less the solution to the question of life’s proliferation here on planet Earth.

One of the more popular iterations of the theory suggests that life actually originated on Mars, and that microscopic organisms were carried away to Earth after a large meteorite impact sent them hurdling across the solar system aboard a Martian rock. But could life have survived such an ordeal?

First of all, there is the question of the initial collision. A meteorite slamming in the Red Planet would have likely killed much of the life around the impact site. The life would then also have to survive the trip to Earth, and then find protection from the immense heat of entry into our planet’s atmosphere.

To test the feasibility of such a theory, Dina Pasini from the University of Kent conducted an experiment where frozen samples of Nannochloropsis oculata – a species of single-celled algae – were fired from a high velocity gas gun into a vat of water.

“As you might expect, increasing the speed of impact does increase the proportion of algae that die,” Pasini explain in a statement. “But even at 6.93 kilometres per second (about 4.3 miles per second), a small proportion survived. This sort of impact velocity would be what you would expect if a meteorite hit a planet similar to the Earth.”

This is actually a major victory for panspermia models, as the initial impact is thought to be the most brutal. If, for instance, the life were incased in ice or rock, it would probably have little trouble making the trip from Mars to Earth. Furthermore, if the sample were also embedded in a meteorite, for example, the high temperatures of atmospheric friction would have had virtually no effect on the life within.

“Our research raises several questions,” Pasini says. “If we find life on another planet, will it be truly alien or will it be related to us? And if so, did it spawn us or did we spawn it? We cannot answer these questions just now, but the questions are not as farfetched as one might assume.”

White Plague Decimating Corals May Be Viral, Not Bacterial

Brett Smith for redOrbit.com – Your Universe Online

Just as the black plague laid waste to communities across Medieval Europe, a ‘white plague’ has been decimating marine corals in the Caribbean.

Once thought to be caused mainly by bacteria, researchers at Oregon State University have found that a group of small, circular, single-strand DNA (SCSD) viruses are connected to the dramatic rise of white plague that has occurred in recent decades.

The Oregon researchers said they are racing to learn more about the disease and how to prevent it because of its widespread, debilitating impact on coral reef health in the Caribbean.

“Twenty years ago you had to look pretty hard to find any occurrences of this disease, and now it’s everywhere,” said study author Nitzan Soffer, a doctoral student in the Department of Microbiology at OSU. “It moves fast and can wipe out a small coral colony in a few days.”

“In recent years the white plague has killed 70-80 percent of some coral reefs,” Soffer said. “There are 20 or more unknown pathogens that affect corals and in the past we’ve too-often overlooked the role of viruses, which sometimes can spread very fast.”

In the study, which was recently published in the Multidisciplinary Journal of Microbial Ecology, the scientists used transmission electron microscopy and genetic sequencing techniques to compare 24 genomes of viruses found in Caribbean corals that had exhibited symptoms of disease.

While the researchers found SCSD viruses in some of the diseased tissue samples, they were unable to find these viruses in healthy corals.

According to the OSU team, marine wildlife diseases are becoming increasingly prevalent. They cited reports of non-bleaching coral disease that have increased more than 50-fold since 1965. These diseases are contributing to declines in coral abundance and cover, the scientists added.

White plague is one of the most aggressive coral diseases, causing rapid tissue loss, affecting a wide range of corals and potentially causing partial or total colony collapse. While some bacteria have been associated with the disease, the OSU study indicates that viruses also play a role, perhaps a central one.

The researchers also found that corals with white plague disease had higher viral diversity than their healthier counterparts.

Marine biologists have been emphasizing that rising ocean temperatures that could result from global warming would stress corals and make them more susceptible to disease. The OSU team said temperature may be another factor behind the recent rise of white plague because the disease frequently appears to be at its height near the end of summer.

Overfishing allows more algae to grow on corals and could be helping to spread disease, researchers said. They added that pollution from sewage outflows in some marine habitats may also be compromising coral health.

The researchers concluded by pointing out that viral infection alone does not automatically cause major problems and disease. Many healthy corals can become infected with herpes-like viruses that persist in their system but are not fatal. These symptoms-free viruses are frequently found in other vertebrate hosts, including humans.

Gene-Expression-Based Biomarker Predicts Long-Term Risk Of Breast Cancer Recurrence

Assay accurately distinguishes patients at continued risk after five years of estrogen-blocking therapy from those who need no additional treatment

A comparison of three methods of predicting the risk of recurrence in women treated for estrogen-receptor (ER)-positive breast cancer finds that only the breast cancer index (BCI) – a biomarker based on the expression levels of seven tumor-specific genes – accurately identifies patients who continue to be at risk after five years of treatment with either tamoxifen or the aromatase inhibitor anastrozole. The study comparing the BCI with two other prognostic tests has been published online in Lancet Oncology.

“We have validated a unique ‘fingerprint’ in the primary tumor of breast cancer patients that can help identify a high or low risk of cancer recurrence,” says study co-author Paul Goss, MD, PhD, director of the Breast Cancer Research Program at Massachusetts General Hospital (MGH) Cancer Center. “This should enable us to offer prolonged treatment to patients who remain at risk and, importantly, to avoid the costs and side effects of treatment in those at low risk.”

Standard treatment for early-stage, ER-positive breast cancer includes five years of treatment with either tamoxifen or an aromatase inhibitor, drugs that block the action of estrogen. While that approach is sufficient for most patients, some continue to experience recurrence during subsequent years. The study authors note that knowing whether or not a patient continues to be at risk is essential to determining whether prolonged treatment is necessary.

MGH researchers previously developed, in collaboration with investigators from bioTheranostics, Inc., two biomarkers for recurrence risk assessment – the molecular grade index, which measures expression levels of five genes related to tumor proliferation; and the H/I ratio, which compares expression levels of two other genes. BCI is a combination of both biomarkers and has been shown to identify patients who are at risk of early recurrence despite receiving hormonal treatment.

The current study, led by Dennis Sgroi, MD, of the MGH Cancer Center and Department of Pathology, was designed to compare the ability of the BCI to predict long-term recurrence risk with that of two other gene-expression signatures that can predict risk in the first five years – the Oncotype Dx Recurrence Score, the current gold standard for guiding clinical decision making, and the less frequently used ICH4 gene signature. All three methods were used to analyze primary tumor samples from more than 650 participants in a clinical trial comparing tamoxifen with anastrozole. Assay results were compared with patient records to determine individual rates of recurrence up to 10 years after initial surgical treatment.

While all three methods were able to predict recurrence risk in the first five years, only the BCI was able to accurately assess long-term recurrence risk. In fact, the BCI was able to clearly distinguish 60 percent of patients whose risk was quite low from 40 percent who continued to be at significant long-term risk. “We know that more than half the instances of recurrence in ER-positive breast cancer occur after five years of therapy with tamoxifen or anastrozole, so these findings are highly relevant to clinical management,” says Sgroi. “Since the BCI identifies two distinct risk groups, it may provide a much-needed tool in determining those patients who need extended hormonal therapy and those who may be spared its well-known adverse side effects.”

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Scientists Accidentally Discover World’s Thinnest Glass

Michael Harper for redOrbit.com – Your Universe Online

Scientists from Cornell University and the University of Ulm in Germany happened upon a world record-setting discovery.

A stroke of good luck led scientists to find the world’s thinnest piece of glass, measuring only two atoms thick. The glass was understandably easy to miss and was only seen when viewed through an electron microscope.

The scientists called the team from Guinness World Records, which titled their discovery ‘World’s Thinnest Glass.’ The scientists had actually been working to create a pure form of graphene, but one thing led to another and they found they had, instead, created an extremely thin film of glass.

More than a happy accident, the team can now examine this film of glass to better understand two-dimensional crystals in glass, something which has rarely been studied.

The glass was first discovered when they noticed a layer of what they call “muck” where they had been producing graphene. Putting the layer under an electron microscope, the scientists noticed the two-dimensional crystals resembled glass made of silicon and oxygen.

“In stark contrast with two-dimensional crystals such as graphene and monolayer hexagonal boron nitride, 2D glasses remain almost completely unexplored,” reads the corresponding paper for Cornell. “These materials, particularly if they cane [sic] isolated from substrates and free manipulated, may have enormous applicability.”

The American and German scientists scored another first as well; the images they took to record the moment are the first ever to show this arrangement of atoms that make up the glass. They believe the accident occurred when air reacted with some copper foils used in the graphene process and a quartz furnace.

As it turns out, one other man nearly discovered this two-dimensional and incredibly thin glass in 1932. According to the researchers, physicist William Houlder Zachariassen nearly categorized this arrangement of atoms in his research. The team says their images of the two-atom-thin glass closely resemble Zachariassen’s cartoon models of 2D continuous network glasses.

The team will now begin researching how these thin layers of glass are mapped out, why they exist, and how they can be used in future applications. So far they suggest this two-dimensional glass and others like it could be used in devices that use layers of graphene.

“Because the silica glass can be easily removed from the copper substrate and contains no dangling bonds, it may also find application in semiconductor or layered graphene electronics as a passivated starting layer for gate insulators,” write the scientists.

Estrogen, Not Just Testosterone, Responsible For Male Sex Drive

Michael Harper for redOrbit.com – Your Universe Online

It’s not just a lack of testosterone – the hormone commonly associated with manliness -which can cause middle-aged men to gain weight and lose their sex drive. According to a new study by researchers at Massachusetts General Hospital, a drop in estrogen levels can also leave these men feeling flabby and less than amorous.

Testosterone has long been thought to be the culprit for a perceived stronger sex drive in men than in women. Yet this new study, published in the latest edition of the New England Journal of Medicine, finds that estrogen may also be responsible for guiding men’s sex drives.

It’s long been known that the body converts estrogen into testosterone, but this study furthers this understanding and casts a larger role for estrogen in the overall sex drive of men. Joel Finkelstein is an endocrinologist at Massachusetts General Hospital and authored this groundbreaking new study of hormones and sexuality.

“This study establishes testosterone levels at which various physiological functions start to become impaired, which may help provide a rationale for determining which men should be treated with testosterone supplements,” explains Finkelstein in a statement to the AFP.

“What will surprise many people is that loss of sexual desire in men with low testosterone is due to lack of estrogen.”

As men get into their 30s and 40s, their testosterone levels begin to drop, diminishing their muscle mass, reducing their sex drive and adding stubborn pounds to their midsections. Drug companies have successfully capitalized on this natural condition and labeled the transition “low T syndrome” in efforts to sell testosterone supplements to these men.

After studying nearly 300 healthy men, Finkelstein and his research team found that increases in estrogen were more responsible for the weight gain than decreases in testosterone levels.

The study participants were between the ages of 20 and 50, and were given supplements meant to suppress both hormones. Afterwards, half of the men were given either a testosterone-boosting gel or a placebo. The second group of men were given the testosterone gel and a drug which further lowered the production of estrogen.

After receiving this battery of hormone therapy, the volunteers in the first group saw the same kind of increase in their body fat normally indicative of low testosterone levels. Any further reduction in lean body mass, such as shrinking thigh muscles and overall strength, didn’t occur until testosterone levels became much lower. As the male hormone continued to drop, so too did the sexual drive of the men in the first study group. These men were still able to achieve an erection, however, until their testosterone levels reached their lowest points.

The second group of men who had their estrogen suppressed also saw increases in body fat and decreases in lean body mass, but their sexual drives were more affected than those men in the first group. Observing these results, Finkelstein now believes estrogen is more closely related with a man’s sexual drive, while testosterone is mainly responsible for a reduction in lean body mass and weight gain.

These findings could change the way some pharmaceuticals target men looking to increase their sex drive through hormone therapy. Though Finkelstein’s research has pointed out that estrogen might be a better way to boost a man’s sex drive, he also warns that increasing this hormone could lead to other, potentially negative side effects.

“We also need to look into how testosterone replacement therapy would effect prostate health – both prostate cancer and the prostate enlargement that causes unpleasant symptoms in many older men – and heart disease,” Finkelstein said.

Oxytocin May Help Autistic Children Experience Reward

redOrbit Staff & Wire Reports – Your Universe Online

Researchers at the Stanford University have shown that oxytocin, the so-called “love hormone,” is involved in a wider range of social interactions than previously understood, findings that may have implications for neurological disorders such as autism as well as scientific conceptions of our evolutionary heritage.

Scientists estimate that the advent of social living preceded the emergence of pair living by about 35 million years. The current study suggests that oxytocin’s role in one-on-one bonding likely evolved from an existing, broader affinity for group living.

Oxytocin is involved in the formation and maintenance of strong mother-child and sexual attachments, and has long been of interest for its apparent roles in establishing trust between people. The drug has recently been administered to children with autism spectrum disorders in clinical trials.

The current study identifies a unique way in which oxytocin alters activity in a part of the brain that is vital to experiencing the pleasant sensation neuroscientists call “reward.”

The findings, published in the journal Nature, validate ongoing trials of oxytocin in autistic patients, and also suggest possible new treatments for neuropsychiatric conditions in which social activity is impaired, the researchers said.

REWARD SYSTEM

“People with autism-spectrum disorders may not experience the normal reward the rest of us all get from being with our friends,” said Robert Malenka, MD, PhD, the study’s senior author. “For them, social interactions can be downright painful. So we asked, what in the brain makes you enjoy hanging out with your buddies?”

Some genetic evidence suggests the awkward social interaction that is a hallmark of autism spectrum disorders may be at least in part oxytocin-related. Certain variations in the gene that encodes the oxytocin receptor – a cell-surface protein that senses the substance’s presence – are associated with increased autism risk.

Malenka has spent nearly two decades studying the reward system, a network of interconnected brain regions responsible for our sensation of pleasure in response to a variety of activities such as finding or eating food when we’re hungry, sleeping when we’re tired, having sex or acquiring a mate, or even taking addictive drugs.

This reward system has evolved to reinforce behaviors that promote our survival, he explained.

For the current study, Malenka and lead author Gül Dölen, MD, PhD, a postdoctoral scholar in Malenka’s Lab with over 10 years of autism-research expertise, untangled the complicated neurophysiological underpinnings of oxytocin’s role in social interactions. They focused on biochemical events taking place in a brain region called the nucleus accumbens, known for its centrality to the reward system.

SOCIAL LINK IN ANIMALS

During the 1970s, biologists learned that in prairie voles, which mate for life, the nucleus accumbens is replete with oxytocin receptors. Disrupting the binding of oxytocin to these receptors impaired prairie voles’ monogamous behavior. In many other species that are not monogamous by nature, such as mountain voles and common mice, the nucleus accumbens appeared to lack those receptors.

“From this observation sprang a dogma that pair bonding is a special type of social behavior tied to the presence of oxytocin receptors in the nucleus accumbens. But what’s driving the more common group behaviors that all mammals engage in – cooperation, altruism or just playing around – remained mysterious, since these oxytocin receptors were supposedly absent in the nucleus accumbens of most social animals,” said Dölen.

The current study shows that mice do indeed have oxytocin receptors at a key location in the nucleus accumbens and, importantly, that blocking oxytocin’s activity there significantly diminishes these animals’ appetite for socializing. Dölen, Malenka and colleagues also identified, for the first time, the nerve tract that secretes oxytocin in the region, and determined the effects of oxytocin release on other nerve tracts projecting to this area.

Mice can squeak, but they can’t talk, Malenka remarked. “You can’t ask a mouse, ‘Hey, did hanging out with your buddies a while ago make you happier?'”

To investigate the social-interaction effects of oxytocin activity in the nucleus accumbens, the researchers used a standard measure known as the conditioned place preference test.

“It’s very simple,” Malenka said. “You like to hang out in places where you had fun, and avoid places where you didn’t. We give the mice a ‘house’ made of two rooms separated by a door they can walk through at any time. But first, we let them spend 24 hours in one room with their littermates, followed by 24 hours in the other room all by themselves. On the third day we put the two rooms together to make the house, give them complete freedom to go back and forth through the door and log the amount of time they spend in each room.”

Mice normally prefer to spend time in the room that reminds them of the good times they enjoyed in the company of their buddies. However, that preference disappeared when oxytocin activity in their nucleus accumbens was blocked.

Interestingly, only social activity appeared to be affected, while there was no difference, for instance, in the mice’s general propensity to move around.

When the researchers trained the mice to prefer one room over the other by giving them cocaine (which mice love) only when they went into one room, blocking oxytocin activity didn’t stop the mice from picking the cocaine den.

SEROTONIN LINK

In an extensive series of complex, highly technical experiments, the researchers located the oxytocin receptors in the murine nucleus accumbens. These receptors lie not on nucleus accumbens nerve cells that carry signals forward to numerous other reward-system nodes, but at the tips of nerve cells forming a tract from a brain region called the dorsal Raphe, which projects to the nucleus accumbens.

The dorsal Raphe secretes another important substance, serotonin, which triggers changes in nucleus accumbens activity.

Popular antidepressants such as Prozac, Paxil and Zoloft belong to a class of drugs called serotonin-reuptake inhibitors, which increase available amounts of serotonin in brain regions, including the nucleus accumbens.

As the Stanford team found, oxytocin acting at the nucleus accumbens wasn’t simply squirted into general circulation, as hormones typically are, but was secreted at this spot by another nerve tract originating in the hypothalamus, a multifunction midbrain structure.

Oxytocin released by this tract binds to receptors on the dorsal Raphe projections to the nucleus accumbens, in turn liberating serotonin in this key node of the brain’s reward circuitry. The serotonin causes changes in the activity of yet other nerve tracts terminating at the nucleus accumbens, ultimately resulting in altered nucleus accumbens activity – and a happy feeling.

“There are at least 14 different subtypes of serotonin receptor,” said Dölen. “We’ve identified one in particular as being important for social reward. Drugs that selectively act on this receptor aren’t clinically available yet, but our study may encourage researchers to start looking at drugs that target it for the treatment of diseases such as autism, where social interactions are impaired.”

Malenka and Dölen believe their findings in mice are highly likely to generalize to humans because the brain’s reward circuitry has been so carefully conserved over the course of hundreds of millions of years of evolution. This extensive cross-species similarity likely stems from pleasure’s absolutely essential role in reinforcing behavior likely to boost an individual’s chance of survival and procreation.

Europe’s Hottest Days Are Even Hotter Because Of Climate Change

redOrbit Staff & Wire Reports – Your Universe Online

While climate change has caused temperatures to spike throughout much of the world, a stretch of Europe from southern England and northern France to Denmark has been especially affected, according to new research published Wednesday in the journal Environmental Research Letters.

Researchers, from the Grantham Research Institute on Climate Change and the Environment at the London School of Economics and Political Science and the University of Warwick, have found that the hottest five percent of days — as well as the coldest nights — in this region of the continent have warmed more than four times the global average since 1950.

In comparison, the average and slightly hotter-than-average days have experienced their highest average increase in temperature in southern France and Germany, while in eastern Spain and central Italy, there was been broad warming across all types of days, the researchers said. They also noted that in most regions cooler-than-average days have not warmed as much and in some areas temperature thresholds have been largely unchanged since 1950.

“Climate is fundamentally the distributions of weather. As climate changes, the distributions change. But they don’t just shift, they change shape. How they change shape depends on where you are,” explained lead author Dr. David Stainforth. “In Britain, climate change will feel very different if you live in Northumbria to if you live in Oxfordshire; different again in Devon.”

“Our results also illustrate that the international goal of limiting the increase in global average temperature to [3.6 degrees F] would involve far greater changes for some places and for some aspects of climate, and therefore for particular individuals, communities and industries,” he added.

Using a new method they developed, Dr. Stainforth and his colleagues compiled maps of the changes of European climatic distributions for summer and winter, as well as daytime and nighttime temperatures. They believe that their research will be of great value to climate services and the meteorological community, helping to prepare these individuals and organizations for a drastically-changing set of weather patterns.

“It is common to discuss climate change in terms of changes in global average temperatures but these can be far from people’s perceptions of climate change. The results in this paper begin to provide a picture of how local climate has been changing across Europe. It is a picture which is closer to that experienced by individuals,” said study co-author Professor Sandra Chapman.

“Changes in local climate pose challenges for decision makers across society not just when preparing for the climate of the future but even when planning for the climate of today,” Dr. Stainforth added. “We need to design buildings so that they don’t overheat, decide which are the best crops to plant, and even plan for variations in large scale productivity. These would all benefit from knowledge of how the climate distribution has changed at particular locations. This work begins to provide such information.”

New Study Finds Anorexia Has A Genetic Link, At Least Partially

Brett Smith for redOrbit.com – Your Universe Online

According to the National Institutes of Health, almost 3.8 million Americans will suffer from anorexia at some point in their life. Thought to be primarily psychological in nature, anorexia nervosa may have a partial genetic cause – according to a new report in Molecular Psychiatry.

“These findings point in a direction that probably no one would have considered taking before,” said study author Nicholas J. Schork, a professor at The Scripps Research Institute (TSRI).

A condition that predominantly affects women and young girls, anorexia is marked by a severe eating restriction and emaciation. Individuals with anorexia may also see themselves as fat, express perfectionism, exhibit signs of anxiety or depression, and have obsessive tendencies, said Walter Kaye, a co-author on the study and professor at the University of California, San Diego School of Medicine.

Scientists aren’t entirely sure how anorexia develops in a person, but many suspect cultural, stress, hormonal and social factors.

To explore a potential genetic factor for the condition, TSRI researchers, along with a team of international colleagues, embarked on the largest-ever genetic sequencing study of anorexia. The project was based on genetic data from over 1,200 individuals diagnosed with anorexia and almost 2,000 non-anorexic participants.

In an initial “discovery” phase of the study that included over 330 subjects, the researchers recorded the genetic variants that had already been associated to feeding behaviors or had been cited in previous anorexia studies. Out of the more than 150 genetic candidates, only a small group demonstrated a significant statistical linkage with anorexia in the study cohort.

One of the strongest initial candidates was the gene EPHX2, which is involved in the production of epoxide hydrolase 2 – an enzyme recognized for regulating cholesterol metabolism.

“When we saw that, we thought that we might be onto something, because nobody else had reported this gene as having a pronounced role in anorexia,” said Schork.

After a series of replication studies – each one involving a different group of anorexia patients and control participants, as well as different genetic analysis methods – the scientists continued to see evidence that certain variants of the EPHX2 gene occur more often in people with anorexia.

To cross-reference their findings, the study researchers used existing data from a large-scale, long-term heart disease study. They found that a subset of the implicated genetic variants can alter the normal association between weight gain and cholesterol levels.

“We thought that with further studies this EPHX2 finding might go away, or appear less compelling, but we just kept finding evidence to suggest that it plays a role in anorexia,” said Schork.

The scientists said they weren’t sure what might cause the unusual metabolism of cholesterol that would help trigger or sustain anorexia. Schork suggested that the connection makes sense as individuals with anorexia often have unusually high cholesterol levels, despite being harshly malnourished. Some weight loss studies have shown that people who develop symptoms of depression can also show an increase in cholesterol levels. Other studies have shown that cholesterol has a positive association with mood.

“The hypothesis would be that in some anorexics the normal metabolism of cholesterol is disrupted, which could influence their mood as well as their ability to survive despite severe caloric restriction,” Schork said.

He added that future studies should look into biological effects of EPHX2 and other genetic variants.

Google Wiretapping Charges Are Legit, Says US Appeals Court

Michael Harper for redOrbit.com – Your Universe Online

A US appeals court has upheld a decision against Google and now claims the search giant must be held responsible for violating wiretapping laws. This decision comes after the California company appealed a previous ruling and argued that their collection of data from unsecured Wi-Fi networks was exempt from these laws. A panel of three judges ruled unanimously against Google, however, and now they must face all the charges brought against them.

In 2010 Google admitted that some of their Street View cars had siphoned off personal data from unsecured WiFi networks in residential areas. When accused of breaking wiretapping laws, Google said what they had inadvertently done was no worse than using someone’s network without permission. They agreed to a $7-million settlement over the case in March.

Google’s claim that the networks they accessed were open to the public did not sway the three judges who voted against the Android maker.

“Payload data transmitted over an unencrypted Wi-Fi network is not readily accessible to the general public,” wrote Judge Jay Bybee in the ruling, reported Bloomberg.

“Even if it is commonplace for members of the general public to connect to a neighbor’s unencrypted Wi-Fi network, members of the general public do not typically mistakenly intercept, store, and decode data transmitted by other devices on the network.”

Bybee went even further, stating that the natural end to Google’s argument would lead to “absurd results.” If leeching data from unsecured networks was as innocent as borrowing a neighbor’s network connection, said Bybee, there would be little to stop a hacker from sitting outside a person’s house, monitoring their traffic and intercepting emails.

“We are disappointed in the Ninth Circuit’s decision and are considering our next steps,” said Google in an email statement.

When Google Street View cars rolled past houses and small businesses, an algorithm was used to collect location data by asking wireless networks for their addresses. This system went beyond even this, however, intercepting emails and accessing other personal information without the user’s consent.

Following a complaint from the German government, Google looked into this system and found it was accessing more data than they originally intended. In May 2010 the company acknowledged their mistake and temporarily grounded their Street View cars.

Google often faces security and privacy charges in the US and all over the world for their bold and sometimes legally questionable practices. Though the company claims their collection of data was not intentional, it nonetheless raised the ire of privacy watchdogs who were already quick to call Google out on their behaviors.

“This appeals court decision is a tremendous victory for privacy rights. It means Google can’t suck up private communications from people’s Wi-Fi networks and claim their Wi-Spying was exempt from federal wiretap laws,” explains John Simpson, a privacy project director at Consumer Watchdog.

More recently, Google defended their email scanning practices by saying their customers can’t expect them not to read their emails before they’re sent.

Bizarre Mass Die-Off Of Starfish Baffles Experts

redOrbit Staff & Wire Reports – Your Universe Online

Massive numbers of dead starfish have been observed in the waters around Vancouver, British Columbia over the past two months, and scientists are currently at a loss as to the possible cause of the fatal phenomenon.

Jonathan Martin, a research associate at Simon Fraser University, has observed the mass die-off of both Sunflower seastars (Pycnopodia helianthoides) and morning sun stars (Solaster dawsoni) and has published photos and videos of the event on Flickr and YouTube.

The images were taken at Whytecliff Park, West Vancouver on August 31, and at Kelvin Grove, Lion’s Bay, British Columbia on September 2, where the video footage was captured. The deceased starfish were observed at depths between approximately 20 feet and 50 feet, Martin explained, and similar scenes have been reported by witnesses at other popular dive sites nearby.

In a September 3 blog entry, Christopher L. Mah, a research collaborator with the Smithsonian Institution National Museum of Natural History explains that the white matter visible on the bottom of the YouTube video are “decaying, white tissues and ossicles from sunflower stars.” He also said that other starfish species of different lineages – including the predatory Solaster dawsoni – also appear to be “in various states of distress.”

Martin told National Geographic that he assumed that since the dead starfish were initially found in regions frequented by crabbers, that they might have been caught in traps and lost limbs attempting to escape.

However, as he continued to find remains – even in marine parks that prohibit crab fishing – he realized something else had to be causing the mass die-off. He posted his photos and videos on the Internet, hoping someone else would see them and perhaps be able to provide some insight into possible causes.

Martin contacted Mah, and explained that the starfish “seem to waste away, ‘deflate’ a little, and then just … disintegrate. The arms just detach, and the central disc falls apart. It seems to happen rapidly, and not just dead animals undergoing decomposition, as I observed single arms clinging to the rock faces, tube feet still moving, with the skin split, gills flapping in the current. I’ve seen single animals in the past looking like this, and the first dive this morning I thought it might be crabbers chopping them up and tossing them off the rocks.”

During the second dive in a region closed to fishing, Martin found that the bottom of the waters from approximately 20 to 50 feet “was absolutely littered arms, oral discs, tube feet, gonads and gills … it was kind of creepy.”

Mah speculates that the incident might be linked to a starfish population boom of 2010 or the result of an as yet unknown disease. However, he also wonders why it is affecting other species. So far, there are no clear answers.

National Geographic’s Carrie Arnold notes that earlier this summer, a similar phenomenon was observed by researchers at the University of Rhode Island along the eastern coast of the US. In that event, the investigators saw large numbers of dead Asterias species (part of the same family as the sunflower starfish in the Vancouver area) in 2011, and since then large quantities of dead starfish have been documented from Maine to New Jersey.

“Fisheries and Oceans Canada is worried enough that they’ve asked Martin to go back out and collect samples for them to test in the lab,” Arnold said. “Although the agency has expressed interest in the die-off, Martin says that starfish aren’t a major research priority, and the main burden of investigation and discovery has fallen on him and other divers with an interest in marine ecology.”

Racial, Ethnic Differences In Outcomes Following Stroke Known As Subarachnoid Hemorrhage

Asian/Pacific Islander patients were more likely and Hispanic patients less likely to die of a subarachnoid hemorrhage

Race or ethnicity can be a significant clue in the United States as to who will survive a kind of stroke known as a subarachnoid hemorrhage and who will be discharged to institutional care, a new study has found.

Compared to Caucasians, Asian/Pacific Islander patients were more likely and Hispanic patients less likely to die of a subarachnoid hemorrhage, or SAH, while in the hospital.

African-American patients were more likely than Caucasians to require institutional care following discharge from the hospital, although their risk of death while in the hospital was similar.

The likelihood of needing post-hospital institutional care was similar among Caucasian, Hispanic, Asian/Pacific Islander and Native American patients.

The study was led by Dr. Loch Macdonald, a neurosurgeon and researcher at St. Michael’s Hospital in Toronto and a world leader in subarachnoid hemorrhage research. The results were published online today in the Journal of Neurosurgery.

Subarachnoid hemorrhage–bleeding into the subarachnoid space that surrounds the brain–can increase pressure in the skull, damage or kill brain cells, and deprive the brain of oxygen. It affects 10 in 100,000 people in North America each year, or about 40,000 cases a year. More than 70 per cent of people with SAH either die within 30 days or are permanently disabled.

Dr. Macdonald examined data from the Nationwide Inpatient Sample, a large hospital care database in the United States. He identified 31,631 hospital discharges related to stays for SAH between 2005 and 2010.

“We believe there could be fundamentally important differences between the biological responses of different ethnic groups to diseases like SAH, rather than any difference due to their medical treatment,” Dr. Macdonald said. “If we can understand what the biological basis is for the better outcome of some ethnic groups, then maybe we can develop ways to use the beneficial effects to help everyone with SAH.”

Among patients admitted to the hospital for SAH, 22 per cent died and 42 per cent were discharged to institutional care, such as a rehabilitation or long-term care facility. Race or ethnicity was a significant predictor of both.

Hispanic patients fared best of all racial/ethnic groups. Compared with Caucasians, Hispanic patients were significantly less likely to die while in the hospital and they shared about the same risk of discharge to institutional care.

For black patients, the risk of dying in the hospital was similar to that for Caucasians, but if they survived their hospital stay, black patients had a greater risk of being discharged to institutional care.

Native American patients were more likely than Caucasians to die while in the hospital or to be transferred to institutional care, but these differences were not statistically significant.

Of all the racial/ethnic groups, Asian/Pacific Islander patients were most likely to die during hospitalization. They were also more likely than Caucasians to be discharged to institutional care, but this difference was not significant.

Dr. Macdonald said the better outcomes in Hispanic patients represents what researchers call an “epidemiological paradox.” Hispanics in the United States on average have a lower socioeconomic status, more risk factors and less ease of access to medical care than non-Hispanic Caucasians. Nevertheless, Hispanic ethnicity is associated with lower risks of death from all causes as well as death due to specific diseases.

As to the poor outcomes of Asian/Pacific Islander patients, Dr. Macdonald said they may have more severe SAH or less access to high-quality hospitals.

Dr. Macdonald holds the Keenan Chair in Surgery at St. Michael’s Hospital.

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NASA’s Chris Cassidy, Russians Return To Earth After Space Station Mission

Lawrence LeBlond for redOrbit.com – Your Universe Online

A Russian Soyuz capsule carrying three members of Expedition 36 touched down in the remote wilderness of Kazakhstan at 10:58 p.m. EDT Tuesday evening (8:58 a.m. Kazakh time). NASA’s Chris Cassidy and Roscosmos’ Pavel Vinogradov and Alexander Misurkin were onboard the capsule as it parachuted safely back to Earth, successfully wrapping up 166 days in space.

The trio launched to the International Space Station (ISS) on March 29, racking up 2,656 Earth orbits and traversing more than 50 million miles. During their time aboard the ISS, the crew conducted a number of EVA (extra-vehicular activity) missions. Vinogradov marked his seventh walk in space after completing a single walk during the Expedition 36 mission. He has spent a total of 38 hours and 25 minutes on EVAs. Misurkin conducted three spacewalks bringing his total EVA time to 20 hours and one minute. Cassidy also conducted three spacewalks bringing his career total to six with 31 hours and 14 minutes floating in the silence of space.

Besides taking regular walks outside the ISS, the crew also conducted hundreds of experiments within the confines of the orbiting lab. They were also witness to the docking of the Europe’s ATV-4 cargo spacecraft (Albert Einstein), the Japanese HTV-4 cargo vessel and two Russian Progress resupply ships.

As for total time in space, Vinogradov’s time on this mission puts him 10th on the all-time endurance list, marking 547 days in space. Cassidy’s 166 days in space greatly adds to his previous time in space, which was accounted for only a tenth of the current mission, bringing his total space time to 182 days. This was Misurkin’s first stint in space.

Prior to their scheduled departure of the ISS, Vinogradov officially handed over the reins of the ISS to Fyodor Yurchikhin during a traditional Change of Command Ceremony. Yurchikhin became Commander of Expedition 37 once the trio boarded the Soyuz TMA-08M capsule and undocked from the ISS.

Along with Commander Yurchikhin, Expedition 37 comprises NASA’s Karen Nyberg and ATI’s Luca Parmitano, who will remain on the ISS as a skeleton crew until a new crew arrives in the coming weeks.

Parmitano, who also conducted two spacewalks during the Expedition 36 phase of his time in space, was accompanied by Cassidy on his second spacewalk, which abruptly ended due to a leak discovered inside Parmitano’s helmet, potentially drowning him in space. After returning to the ISS unharmed, the cause of the malfunction was extensively studied; the most likely scenario was that his spacesuit cooling system failed, yet there is no official cause in the books.

Parmitano also became the first Italian to conduct a spacewalk, when he ventured out into the cold, dark vacuum of space on July 9, 2013.

A few days before departing the ISS, Cassidy, who is originally from York, Maine, took some time to talk with Maine’s CBS affiliate WGME 13.

During an exclusive satellite interview, Cassidy explained that his time aboard the ISS has literally “flown” by. He said he would miss the views from space, but was ready to return home to see his friends and family in Maine.

Image Below: In preparation for the Expedition 36 return to Earth, Commander Pavel Vinogradov of Russia’s Federal Space Agency (Roscosmos) handed over control of the International Space Station Monday, Sept. 9, 2013 at 2:25 p.m. EDT in a traditional Change of Command Ceremony. Roscosmos Flight Engineer Fyodor Yurchikhin will take over command and officially lead Expedition 37 when Expedition 36 undocks Tuesday at 7:35 p.m. In the bottom half of this photo, left to right, are Vinogradov and Flight Engineers Karen Nyberg of NASA and Misurkin. In the top half of the photo are, left to right, Flight Engineers Luca Parmitano of the European Space Agency, Cassidy, and Yurchikhin. This photo was taken on June 8, 2013. Credit: NASA

Apes Demonstrate Ability To Classify Animals Based On Biological Features

redOrbit Staff & Wire Reports – Your Universe Online

Gorillas and orangutans can categorize images based on various biological categories in much the same way that young human children learn how to tell living beings from inanimate objects or dogs from cats, according to new research appearing in the open-access journal PeerJ.

Scientists have determined that there are at least two ways in which animals can be visually identified as being similar in nature to any other animal: they could be members of the same genus or species, thus closely resembling each other, or they may be evaluated for a different type of criteria (such as a reptile’s lack of fur). The first method searches for perceptual differences, while the other searches for conceptual differences.

There have been many studies examining concept formation in human children, the researchers explained, with great emphasis on the relationship between concept acquisition and language acquisition. Experts have suggested that broader concepts are reliant upon formal scientific training, as well as the ability to form verbal labels for those notions. If non-human animals can represent such concepts, it would be evidence against this hypothesis.

Given the existence of natural categories such as the classifications of animals, the team behind the new study expressed surprise that the language-less, non-human apes had not been observed regarding this phenomenon. Rather, concept-related studies in animals have focused primarily on the perceptual features used by those creatures to extract information about category membership without allowing animals to demonstrate whether or not they are capable of forming concepts at different levels of breadth at the same time.

Led by Dr. Jennifer Vonk, an associate professor at the Oakland University’s Department of Psychology, the researchers analyzed a young female gorilla and four orangutans of various ages. The apes were presented with images of various animals. In one study, the apes were asked to match each one with an image from the same species of family. In another, they were given pictures of animals belonging to different taxonomic classes and asked to match them to sample images of other members of the same class.

In the experiment involving images from the same taxonomic class (i.e. different reptiles or mammals), there were fewer perceptual features, which would theoretically make it harder for the apes to correctly match the images using perceptual strategies. However, Dr. Vonk’s team found that the orangutans were actually able to match pictures from the same groups at a higher level of accuracy than they were able to from within the same species or family.

This discovery indicates that the apes may have developed a concept for animal classes that goes beyond their perceived similarities. Like the orangutans, the gorilla was also able to learn these concepts, but required additional testing than with the concepts involving same-species creatures. The researchers explain that the class level distinctions are analogous to those learned early on during human development.

“The ability of other apes to match stimuli at the level of taxonomic class is a novel finding that tells us that abstract categories can be extracted from visual stimuli in the absence of biological information, verbal labels, or extensive experience with the objects,” Dr. Vonk said. “This finding suggests that orangutans, and perhaps gorillas, may share an underlying conceptual process with humans.”

ExoMars Rover To Test For Microbial Life On The Red Planet

John P. Millis, PhD for redOrbit.com – Your Universe Online

In 2018, the European Space Agency (ESA) will launch a new mission to Mars called ExoMars. Armed with new instruments, this explorer will beam back information about various conditions and properties on the Red Planet’s surface. One such instrument will be the Raman spectrometer – a device similar to a bomb detector that will search for evidence for life.

The Raman spectrometer has the ability to detect life that has been damaged by significant levels of radiation – an environment certainly reminiscent of Mars, which lacks a protective atmosphere and magnetic field. According to Lewis Dartnell of the University of Leicester: “Raman spectroscopy is a wonderfully sensitive and versatile technique. It can reveal details of the minerals inside rocks, and so what the micro-environment for life is, but we can also use it to detect organic molecules and signs of life itself.”

In testing the spectrometer, Dartnell and his team exposed bacteria to high doses of radiation, thousands of times the level that would kill a human, and found that carotenoid molecules – a key marker of life – could still be identified.

“What we’ve been able to show is how the tell-tale signature of life is erased as the energetic radiation smashes up the cells’ molecules,” said Dartnell. “In this study we’ve used a bacterium with unrivalled resistance to radiation as a model for the type of bacteria we might find signs of on Mars.”

“What we want to explore now is how other signs of life might be distorted or degraded by irradiation. This is crucial work for understanding what signs to look for to detect remnants of ancient life on Mars that has been exposed to the bombardment of cosmic radiation for very long periods of time.”

But the most important question of all remains: Did life ever evolved on the Martian surface to start with? The ExoMars mission, armed with the Raman spectrometer may begin to provide some answers when it launches in 2018.

Brain Researchers Find Early Warning For Cognitive Decline

Brett Smith for redOrbit.com – Your Universe Online

Two new studies have revealed readily-detectable, early-warning signs of cognitive impairment.

One study from researchers at the University of California, Davis revealed that the degeneration of a small structure deep in the brain called the fornix provides early clues for the future onset of memory loss or dementia. The other study from the University of Toronto in Canada showed a new link between early-onset Parkinson’s disease and a piece of DNA missing on chromosome 22.

In the UC Davis study, researchers recruited over 100 cognitively healthy people with an average age of 73. Participants underwent brain scans using magnetic resonance imaging (MRI) that revealed their brain volumes and integrity. The researchers also administered psychological tests and cognitive assessments to the participants to score their level of mental function. The study volunteers returned for MRIs and cognitive assessment at about one-year intervals.

At the beginning of the study, none of the participants showed signs of mental decline. Over time, about 20 percent began to exhibit symptoms that would eventually lead to a diagnosis of mild cognitive impairment (MCI) or, in a few cases, Alzheimer’s disease.

The researchers found that variables related to the fornix, an organ that ferries messages to and from the hippocampus, are measurable brain factors that precede cognitive deterioration, according to their report in the JAMA journal Neurology.

“Although hippocampal measures have been studied much more deeply in relation to cognitive decline, our direct comparison between fornix and hippocampus measures suggests that fornix properties have a superior ability to identify incipient cognitive decline among healthy individuals,” said study author Evan Fletcher, a project scientist with the UC Davis Alzheimer’s Disease Center.

“We found that if you looked at various brain factors there was one — and only one — that seemed to be predictive of whether a person would have cognitive decline, and that was the degradation of the fornix,” Fletcher said.

In the Parkinson’s-related study, Toronto researchers discovered that people between the ages 35 and 64 who were missing a specific part of chromosome 22 had a higher risk of developing Parkinson’s disease compared to their peers in the general population, according to their report which also appeared in JAMA Neurology.

The genetic omission of about 50 genes from chromosome 22 is associated with a condition called 22q11.2 deletion syndrome. Individuals with this condition may have birth defects, learning difficulties, and potentially develop schizophrenia. The genetic condition occurs in 1 out of every 2,000 to 4,000 births and is thought to be under-diagnosed.

“Our discovery that the 22q11.2 deletion syndrome is associated with Parkinson’s disease is very exciting,” said study author Dr. Anthony Lang, a neurologist from the University of Toronto. “The varying pathology that we found is reminiscent of certain other genetic causes of Parkinson’s disease, and opens new directions to search for novel genes that could cause its more common form.”

“Studies of patients with 22q11.2 deletion syndrome before they ever develop clinical features of Parkinson’s disease may not only provide important information on the effectiveness of screening methods for early detection of the disease, but also allow for future ‘neuroprotective treatments’ to be introduced at the ultimate time when they can have a chance to make an important impact on preventing the disease or slowing its course,” Lang added.

“Most people with 22q11.2 deletion syndrome will not develop Parkinson’s disease,” said co-author Dr. Anne Bassett, a geneticist at the University of Toronto. “But it does occur at a rate higher than in the general population. We will now be on the look-out for this so we can provide the best care for patients.”

MRI May Predict Heart Attack And Stroke Risk In People With Diabetes

Whole-body MRI may serve as a valuable noninvasive tool for assessing the risk of heart attack and stroke in diabetic patients, according to a new study published online in the journal Radiology.
Diabetes is a metabolic disease characterized by an increased concentration of glucose in the blood. There are 347 million diabetic patients worldwide, and the World Health Organization projects that diabetes will be the seventh leading cause of death by 2030.
Patients with diabetes are known to develop atherosclerosis, or thickening of the arterial walls, at an accelerated rate, resulting in a higher incidence of major adverse cardiac and cerebrovascular events (MACCE), such as a heart attack or stroke. However, there are wide variations in the degree of risk for adverse events among diabetic patients.
In recent years, whole-body MRI has emerged as a promising means to assess the cardiovascular systems of people with diabetes.
“One of the major advantages of whole-body MRI in this population is that the technique itself is not associated with radiation exposure, and larger body areas can be covered without increased risk, especially in younger patients,” said Fabian Bamberg, M.D., M.P.H., from the Department of Radiology at Ludwig-Maximilians University in Munich, Germany. “As such, MRI can be used to evaluate the whole-body degree of disease burden that is not clinically apparent yet.”
Dr. Bamberg and colleagues studied the predictive value of whole-body MRI for the occurrence of MACCE in 65 patients with diabetes. The patients underwent a contrast-enhanced whole-body MRI protocol, including brain, cardiac and vascular sequences. The researchers then conducted follow-up inquiries to assess the rate of MACCE in the study group.
Follow-up information was available for 61 patients. After a median of 5.8 years, 14 patients had experienced MACCE. Patients who had detectable vascular changes on whole-body MRI faced a cumulative MACCE risk rate of 20 percent at three years, and 35 percent at six years. None of the patients with a normal whole-body MRI went on to experience MACCE.
The findings point to a role for whole-body MRI as an accurate prognostic tool for diabetic patients that could speed effective treatments to those at risk, Dr. Bamberg said.
“Whole-body MRI may help in identifying patients who are at very high risk for future events and require intensified treatment or observation,” he said. “Conversely, the absence of any changes on whole-body MRI may reassure diabetic patients that their risk for a heart attack, stroke or other major cardiac or cerebrovascular event is low.”
Along with its prognostic accuracy, whole-body MRI has other advantages over existing methods of determining heart attack risk, according to Dr. Bamberg.
“Other established and valuable tools, such as myocardial perfusion imaging or computed tomography (CT) for quantification of coronary calcification, are generally limited to cardiac evaluation due to their associated risk profiles,” he said. “Also, MRI provides unique insights into soft tissue pathology, including cerebral and vascular changes, such as restriction of blood flow to the brain.”
Dr. Bamberg said that while whole-body MRI is a relatively recent development that needs more study, the results so far are promising.
“Our study provides preliminary evidence that the technique may be beneficial for risk stratification in patients with diabetes,” he said. “We anticipate that emerging study findings in different diabetic cohorts will provide additional scientific basis to establish whole-body MRI as a screening modality.”

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Important Role In Polar Ocean Carbon Budgets Played By Micro-gels From Tiny Arctic And Antarctic Ice Algae

Aarhus University
Secretion of polysaccharides from the micro community living within the sea ice stick organism together and forms greater particles introducing a rapid transport of carbon to the seafloor. New research now makes it possible to forecast the importance for the global carbon budget of this transport.
A community of microscopic algae and bacteria thrives within the Arctic and Antarctic pack ice. These ice-organisms are adapted to growing on the ice crystal surfaces and within a labyrinth of channels and pores that permeate the ice floes.
It is a hostile place to grow with temperatures often at -10°C to -20°C, low light and within six or seven times more salty brines in the ice channels compared to the underlying seawater from where these organisms originate.
Many marine organisms secrete gel-like substances in response to environmental stress, and these ice-dwellers are no exception. In fact they secrete large quantities of gels that are made up from various types of polysaccharides.
A new study released in Proceedings of the National Academy of Science, now demonstrate that these gels from ice-microorganisms are important in both the Arctic and Antarctic. It is likely that they will not only affect the physical structure within the ice but also how carbon travels to the ocean floor and even the weather.
Sticky masses
The gels promote the clumping together of cells when they are released from the ice when it melts. These sticky masses fall more rapidly to the sea floor, taking carbon (and food) out of the surfaces waters.
There is also evidence that micro-gels at the ocean surface may get caught up into the air and eventually act as cloud condensing nuclei thereby affecting weather. The gels therefore have profound implications for both the long-term burial of carbon to the ocean floor and thus the global carbon budget and on the weather.
Since 2006 Professor Graham Underwood & Dr Shazia Aslam from University of Essex and Professor David Thomas from Arctic Research Centre, Aarhus University have led several projects (funded by the Natural Environment Research Council, UK) to study the production of micro-gels, and their widespread importance to the frozen realms of the worlds oceans. They teamed up with colleagues from Australia and Canada to collect and analyze ice cores from both the Arctic and Antarctic.
Seven years on, and many frozen trips later, they now publish a rather surprising finding. Analyzing ice data spanning ice from both the Arctic and Antarctic, they are now able to determine the amounts of gel production from the ice microbes based on data of the physical nature of the ice and the amount of microbiology.
“It means that we can estimate the concentration of gels in ice, by knowing rather routine measurements such as the thickness of the ice floes, temperature and salinity of the ice and the quantity of ice biology measured as the chlorophyll content of the ice,” says Professor David Thomas, Arctic Research Centre, Aarhus University.
“This is a huge step forwards to enable us to estimate the significance of these materials to the millions of square kilometres of Antarctic and Arctic pack ice”, says Thomas.

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Erogenous Zones: Separating Myth From Fact

Michael Harper for redOrbit.com – Your Universe Online

Erogenous zones, or those areas of the body which arouse a person sexually, have long been puzzling to neuroscientists and other researchers. It had been widely assumed, of course, that most men have just one area of the body that gets them aroused, while many women can be stimulated in various areas to produce arousal. And then there’s issue of feet: How can feet be so sexually appealing to certain members and so repulsive to others?

Scientists from Bangor University’s School of Psychology and the University of the Witwatersrand in Johannesburg set out to answer these questions and found a few surprises along the way. Most notably, men were reported to have nearly as many erogenous zones as women, dispelling a long-held myth. Finally, nearly every one of the 800 people surveyed found the feet wholly unappealing. The study is now published in the neuroscience journal Cortex.

“A lot of people assume that women’s bodies are just full of erogenous zones and that men have only one, the obvious one,” explained professor Oliver Turnbull with Bangor University in a statement to The Guardian. “It’s pretty equal, with just perhaps a modest advantage to women – but certainly nothing like the way the sex differences have been so hugely exaggerated.”

The scientists were surprised in another way as well – each of the 800 respondents gave very similar responses when listing the areas of the body which aroused them the most. Despite differences in age, gender, nationality, race or sexual orientation, the same areas of the body were generally listed that provide people with that special feeling. The genitals were an obvious source of pleasure for these people, with ears, inner thighs and shoulder blades rounding out the list.

“We have discovered from this that we all share the same erogenous zones in at least two very different continents, whether we are a white, middle-aged, middle-class woman sitting in a London office or a gay man living in a village in Africa. It suggests it is hardwired, built in, not based on cultural experience,” Turnbull said.

One area which was not commonly on the list, however, was a person’s feet. The survey participants, who lived mostly in the British Isles and Sub-Saharan Africa, rated the feet “surprisingly low,” said the researchers. This was particularly surprising to Turnbull and his colleagues as it was previously understood that the sensors wired to a person’s feet in the brain were next to the sensors which guide the genitalia. The kneecaps were rated just above the feet in this study.

Men and women may have nearly the same number of erogenous zones on their body, but they’re not without their preferences. Men, for instance, were found to prefer being stroked on their hands as well as the backs of their legs.

Turnbull and team weren’t so much interested in understanding where the erogenous zones were as understanding why they were. It makes clear sense why they genitals are considered erogenous, but why is a portion of the body so far removed from the genitals as the shoulder blades responsible for getting people in the mood? In short, the researchers now believe a different part of the brain is responsible for guiding these zones. Finding exactly where that part of the brain is, however, could be difficult.

“I think there is a good argument for it being the insular [cortex], although there are a few ethical issues in trying to take the next step and measure that, as it obviously means that someone has to be stroking someone else whilst the brain is monitored,” said Turnbull.

Used Coffee Grounds Could Help Create Clean, Cheap Fuel

[ Watch the Video: Biodiesel From Used Coffee Grounds ]

redOrbit Staff & Wire Reports – Your Universe Online

A large percentage of people turn to coffee for energy to start their day, but new research suggests that the caffeinated beverage could also serve as fuel to power automobiles and appliances.

Yang Liu of the University of Cincinnati’s College of Engineering and Applied Science (CEAS) and colleagues report that an ingredient in old coffee grounds could be converted into energy sources, including biodiesel and activated carbon, through a three-step process.

First, oil would be extracted from the waste. The coffee grounds would then be dried in order to filter impurities in biodiesel production, and then the remains would be burned as an alternative energy source for electricity (similar to biomass). Liu presented his research this week at the American Chemical Society’s (ACS) 246th National Meeting & Exposition in Indianapolis.

The project launched in 2010 and is currently in its early stages, but the results thus far have been deemed promising, the university said in a statement. What started as research involving the collection of waste coffee grounds from an on-campus Starbucks could ultimately lead to cheaper, cleaner fuel for cars, furnaces, and other energy sources, according to Liu and his associates.

After collecting the grounds, the researchers removed the oil and converted the triglycerides in that oil into biodiesel and its byproduct glycerin. The coffee grounds were then dried and used to purify the biodiesel, and the preliminary results demonstrated that the oil content in the waste was between 8.37-19.63 percent, and that the biodiesel made from coffee oil meets the ASTM International D6751 standard.

“The efficiency of using the waste coffee grounds as a purification material to remove the impurities in crude biodiesel, such as methanol and residual glycerin, was slightly lower compared with commercial purification products,” the university said.

“However, the researchers report that results still indicate a promising alternative, considering the cost of purification products. Future research will continue to focus on improving the purification efficiency of waste coffee grounds-derived activated carbon,” they added.

The result could be a cheaper, cleaner-burning fuel source. Biodiesel reduces the emission of carbon monoxide, hydrocarbons and particulate matter versus petroleum diesel, the researchers said. Creating it using waste material that is a byproduct of brewing one of the world’s most popular beverages would be inexpensive, and would prevent an estimated one million tons of primarily landfill waste from being produced in the US each year.

“The researchers say the method they’re exploring to produce biodiesel would not only open landfill space, but it also holds promise in creating biodiesel from a natural product that’s not also in high demand as a food source, such as corn and soybean crops that are used to manufacture biodiesel,” the university said.

“The project was among four proposals selected for a $500 grant last spring from the UC Invents initiative, an enterprise led by UC Student Government and the UC student chapter of the Association for Computing Machinery to share ideas and encourage innovation in campus life,” they added.

Help Needed In Training Robot Swarms – The Daily Orbit

Researchers are giving you a pass to play video games.

Why is NASA so “smart?”

Fuel for you and your car.

And grounds for more discussion on the Daily Orbit!

Hello and welcome to the Daily Orbit I’m Emerald Robinson.

Engineers are swarming to video games to learn more about robotics. An ongoing study out of Rice University is using free online games to crowd source information to help them refine control algorithms for robotic swarms. And anyone can play! Each time a player successfully navigates a group of robots through a maze or obstacle, the website gathers data about how the task was completed. Researchers are looking at how such swarms could have medical applications such as swarming a tumor with a payload of anti-cancer drugs using MRI signals. One post-doctoral researcher at Rice demonstrated how a swarm of randomly scattered robots could be directed to form a complex shape…in this case the letter R. So citizen scientists unite to play and win—for science’s sake!

So there are smartphones, smartwatches, smart toilets, and now NASA’s working on a smartcamera—with an otherworldly application. A team of scientists at NASA’s Jet Propulsion Laboratory is developing a new camera system for future exploration rovers to not only take pictures of alien rocks but to also think about what the images mean. Currently there is a bottleneck of sorts on information coming back to Earth from the Rover Curiosity. Scientists at NASA are hoping to install a camera on future rovers that can make decisions on its own. For instance, it could take a picture of a rock, analyze it, and decide if it should keep digging in that area or move on. Now that’s a smart camera. Right now there is a delay in communication between rovers on Mars and scientists telling the rover what to do as the signal transmits through space. This delay makes exploration further into the solar system more difficult, but NASA hopes this new camera will help speed things along. Smart thinking NASA 😉

And once again scientists are looking to nature for inspiration. A new study of the tropical blue Morpho butterfly found that its wings have properties which could be mimicked to create a variety of applications from protective clothing to industrial sensors. Tiny tree-like nanostructures on the scales of Morpho wings give it its characteristic metallic blue iridescence. And it’s understanding the physical nanostructures that create this iridescence that scientists say is helping them to understand natural photonics, and implement these “design ideas” in new technologies – like bio-inspired displays, fabrics, and cosmetics.

You know me, I think coffee is one of the greatest gifts on Earth. Here’s more grounds for its greatness: Not only is coffee the fuel you need to start your day, but new research says that it could potentially power your car and appliances as well. Researchers at the University of Cincinnati say old coffee grounds could be converted into energy sources like biodiesel and activated carbon. In their experiment, oil was extracted from the grounds and converted into biodiesel, which was then purified by the remaining grounds—and then the grounds were burned as an alternative source of electricity. And this is cool…researchers collected waste coffee grounds from an on-campus Starbucks for their experiments. That’s where I fuel up in the morning too.

And if I don’t get my morning coffee—you don’t want to be around me. I am definitely addicted to caffeine and I have to have it! A new article published in the Journal of Caffeine Research says that caffeine dependence is far from harmless. Caffeine is one of the two most widely used psychoactive drugs on the planet, second only to alcohol. If you have two-and-half-cups per day—congratulations you’re probably an addict. Based upon a meta-analysis of 122 previous published studies, scientists determined that more research needs to be conducted in order to better understand the clinical signs, risk factors, and best approaches for treating the addiction. So let me get this right—there was a study that found out that there needs to be more studies on caffeine addiction?

And that’s your Daily Orbit! See you tomorrow!

Graphic Anti-Tobacco Ad Campaign Helped 100K People Stop Smoking

redOrbit Staff & Wire Reports – Your Universe Online

An estimated 100,000 people will likely quit smoking permanently as a result of the US Centers for Disease Control and Prevention’s “Tips From Former Smokers” national educational and advertising campaign, the agency announced on Monday.

According to a CDC report, the three-month campaign led an estimated 1.6 million American smokers to try and kick the habit, with over 200,000 successfully doing so after the program. Half of those are expected to never pick up another cigarette, exceeding the original goals of 500,000 quit attempts and 50,000 successful quits.

“This is exciting news,” said CDC Director Dr. Tom Frieden. “Quitting can be hard, and I congratulate and celebrate with former smokers – this is the most important step you can take to a longer, healthier life. I encourage anyone who tried to quit to keep trying – it may take several attempts to succeed.”

The CDC surveyed thousands of adults, both smokers and nonsmokers, prior to and after the campaign. They found that those former smokers who were able to quit added over one-third of a million years of total life to the US population. Nearly 80 percent of smokers and 75 percent of non-smokers recalled viewing at least one of the ads during the campaign, which aired from March 19 through June 10, 2012.

The advertising campaign marked the first time that a federal agency had developed and placed paid advertisements for a national tobacco education campaign, the CDC said. The ads featured personal stories of ex-smokers who now found themselves living with a series of smoking-related diseases and disabilities, and encouraged viewers to call a toll-free hotline set up by the agency for smoking cessation assistance.

Calls to that hotline more than doubled during the campaign, and visits to a quit-assistance website set-up by the CDC were five-times higher than they were over the same 12-week period in 2011, the agency said. The new study on the campaign’s effectiveness was published Monday in the medical journal The Lancet.

“Hard-hitting campaigns like ‘Tips From Former Smokers’ are great investments in public health,” said lead author Tim McAfee, Director of CDC’s Office on Smoking and Health (OSH) within the National Center for Chronic Disease Prevention and Health Promotion. “This study shows that we save a year of life for less than $200. That makes it one of the most cost-effective prevention efforts.”

NASA Developing TextureCam Smart Camera System

[ Watch the Video: Smart Cameras For Future Mars Rovers ]

Brett Smith for redOrbit.com – Your Universe Online

As urgent as interplanetary exploration might seem, NASA must deal with a significant communication delay that acts as a bottleneck between robotic explorers like the Curiosity rover on Mars and scientists here on Earth.

To help address that problem, a team of scientists based at NASA’s Jet Propulsion Laboratory (JPL) in Pasadena, Calif. have developed a new camera system that can not only take pictures of alien rocks, it can also think about what the images mean – allowing it to decide if it should keep exploring a particular area or move on.

The point is to make our robotic explorers more autonomous so they don’t have to check in every time a decision needs to be made.

“We currently have a micromanaging approach to space exploration,” said senior researcher Kiri Wagstaff, a computer scientist and geologist at JPL. “While this suffices for our rovers on Mars, it works less and less well the further you get from the Earth. If you want to get ambitious and go to Europa and asteroids and comets, you need more and more autonomy to even make that feasible.”

Currently, scientists on Earth must upload an agenda to a Mars rover at the beginning of each Martian day, or sol. This scientific itinerary outlines almost all of the rover’s movements: roll forward, snap a photo, collect a soil sample, and so on.

Even though the instructions are transmitted at the speed of light, they take approximately 20 minutes to reach Mars. The 40-minute roundtrip makes real-time control of Curiosity impossible. If NASA were to search for extraterrestrial life on Jupiter’s moon Europa, where scientists suspect life could exist, the delay grows to over 90 minutes.

“Right now for the rovers, each day is planned out on Earth based on the images the rover took the previous day,” said Wagstaff. “This is a huge limitation and one of the main bottlenecks for exploration with these spacecraft.”

Curiosity’s scientific objectives are currently based on the images it sends back to Earth. The relative snail’s pace of these communications costs precious power at a bandwidth of around 0.012 megabits per second—around 250 times slower than a 3G cellphone network connection.

While Mars orbiters can help speed the data transfer rate, the Martian satellites currently in orbit are only in the correct alignment a few short minutes each day, severely limiting the number of Martian images it can transmit to Earth.

“If the rover itself could prioritize what’s scientifically important, it would suddenly have the capability to take more images than it knows it can send back. That goes hand in hand with its ability to discover new things that weren’t anticipated,” Wagstaff said.

According to a report in Geophysical Research Letters, the new system, called TextureCam, can snap 3D images using stereo cameras and a special processor recognizes textures in the photos. The processor uses the size and distance to rocks in the picture to decide if there is anything of scientific importance in the images.

“You do have to provide it with some initial training, just like you would with a human, where you give it example images of what to look for,” said Wagstaff. “But once it knows what to look for, it can make the same decisions we currently do on Earth.”

Wagstaff envisions TextureCam greatly benefiting future Mars rovers, such as the Mars 2020 rover, in addition to missions on other planets and moons.