Parents Do Not Follow Advice Of Their Children’s Pediatricians

Brett Smith for redOrbit.com – Your Universe Online

According to a new national poll from the University of Michigan´s C.S. Mott Children´s Hospital, only about one-third of parents say they always follow their pediatrician´s advice.

“During well-child visits, health care providers give parents and guardians advice about how to keep their kids healthy and safe,” said Sarah J. Clark, an associate director of the National Poll on Children’s Health at the university. “This poll suggests that many parents aren’t heeding that advice consistently, putting kids at risk for long-lasting health concerns.”

According to the poll results, 31 percent of parents said they always follow the recommendations from their child’s health care provider all of the time, while 13 percent reported that they follow the provider’s advice only occasionally.

Socio-economic status had an impact on the poll´s results as households that earned less than $60,000 annually were more than twice as likely to admit that they follow provider advice occasionally, compared to parents from higher-income households, 17 percent to 8 percent, respectively. African American and Hispanic parents are also twice as likely to follow provider advice only occasionally, 22 percent and 18 percent, compared to white parents, at 9 percent.

Clark said that unfortunately many health risks, such as childhood obesity, are closely tied to parenting behaviors. Some parenting behaviors can result in a more immediate threat to their child´s well being, like laying an infant down in a prone position, which is associated with Sudden Infant Death Syndrome (SIDS).

“Even more concerning is that certain populations (poorer families, non-white families) were more likely to report following advice only occasionally,” Clark said. “The children in these populations are known to have higher rates of health problems such as obesity, SIDS, and tooth decay.”

In an encouraging sign, 56 percent of parents said they follow their health care provider’s advice “most of the time.”

The study went into greater detail by asking parents to choose what type of advice they were most and least likely to follow. Parents who reported occasionally following provider advice said they were most likely to follow advice on nutrition, going to the dentist, and using child car seats. They said they were least likely to follow advice on discipline, putting the child to sleep and time watching TV.

The poll also showed that parents’ approval rating of their provider is closely linked to whether or not they follow provider advice. Forty-six percent of parents who rated their child’s provider as “good/fair/poor” said they follow provider advice only occasionally.

Hospital officials who conducted the poll said overcoming dissatisfaction among certain parents could be the key to raising health outcomes for children. They added that providers need to reach out to parents and connect with them over the health of their children.

“Providers should work on using clear language, asking parents about their concerns, and giving practical examples of what works with children of different ages,” Davis said.

He added that parents also have a role in communicating with their provider.

“This poll suggests that parents need to ask for clarification if they are unsure about what the provider is saying, or why it’s important,” Davis said.

Parents Skip HPV Vaccination In Teenage Daughters Due To Safety, Side Effect Concerns

Lawrence LeBlond for redOrbit.com – Your Universe Online

Concerns about safety and side effects of receiving the human papillomavirus (HPV) vaccine have left many parents guarded about offering the option to their teenage daughters, even with increased recommendations by health experts.

Paul Darden, MD, of the University of Oklahoma Health Sciences Center, and colleagues have found that more than 40 percent of parents reported in 2010 that they did not plan to vaccinate their teen daughters against HPV. They reported their findings in the April issue of Pediatrics. The study also included research by the Mayo Clinic.

Furthermore, Darden and his colleagues found that 16 percent of parents cited fears as the main reason for not getting their female children vaccinated in 2010, up from 5 percent in 2008. The total percentage of parents opting not to vaccinate their daughters grew to 44 percent in 2010 from 40 percent in 2008, according to the authors.

For the study, the researchers looked at three vaccines routinely recommended for US teens: one for sexually-transmitted HPV; Tdap, for tetanus, diphtheria and acellular pertussis; and the meningococcal conjugate vaccine (MCV4). The authors found that immunization rates rose for all three vaccines, except for the proportion of girls immunized against HPV.

Senior study author Robert Jacobson, MD, a pediatrician with the Mayo Clinic Children´s Center, said the HPV vaccination rate in girls is going in “the opposite direction.”

As opposed to HPV, only 1 percent of parents fear safety and side effects from their teen daughters receiving the Tdap vaccine.

“You’d expect as people get more familiar with a vaccine that they would actually become more comfortable with it,” said Darden. However, “that doesn’t seem to be the case with HPV.”

The findings suggest that additional approaches may be needed to improve HPV immunization rates in this subset. Detailed discussions about the vaccine and its effectiveness should be maintained between the pediatrician and both the parent and child, he noted.

However, according to William Schaffner, MD, of Vanderbilt University, other reports have shown that “provider hesitancy” could still be playing a role.

He told MedPage Today in an interview that some doctors may be delaying their discussions about the HPV vaccine with parents until their children are older.

“Pediatricians are letting it go in the early teens years [sic] and bringing it up only later,” he said. “Then we’re missing some teens because they tend not to see the doctor as frequently in the late teens as they do around 11, 12, and 13.”

“Pediatricians really do need to continue to be vaccine advocates,” he added.

This is especially true when it comes to HPV, a family of sexually transmitted viruses linked to tumors of the cervix, head and neck and organs. The virus is passed through genital contact, most often during vaginal and anal sex, but also through oral sex.

Data from the US Centers for Disease Control and Prevention (CDC) state that HPV vaccines offer the best protection to both girls and boys who receive it before becoming sexually active, allowing them to develop an immune response. The longer parents wait to vaccinate their teens, the longer it will take to build up immunity, and the less safe their children are if they have a sexual encounter.

For the study, the researchers analyzed data for teens ages 13 to 17 in the 2008-10 National Immunization Survey of Teens. They discovered that as of 2010, 80 percent of teens had the Tdap and 63 percent had the MCV4 vaccine. While the researchers found that immunization rates rose overall for HPV vaccination, only a third of teen girls had received the vaccine.

Parents failed to have their children vaccinated due to a number of reasons: Nine percent said it was not recommended by their child´s pediatrician; some had lack of knowledge; 17 percent believed the vaccine was unnecessary; and 16 percent worried about the safety/side effects of the immunization. Also, 11 percent of parents said that their child was not sexually active.

“HPV causes essentially 100 percent of cervical cancer and 50 percent of all Americans get infected at least once with HPV. It’s a silent infection. You cannot tell when you’ve been exposed or when you have it,” said Jacobson. “While most HPV infections clear, a percentage linger and start the process of cancerous changes. The HPV vaccine is an anti-cancer vaccine.”

Despite reasons that parents give for not vaccinating their teen daughters, there is little evidence that the HPV vaccine has dangerous side effects.

The first HPV vaccine was licensed in 2006, and even then “there was very strong evidence that it was safe,” Jessica Kahn, professor of pediatrics at Cincinnati Children’s Hospital Medical Center, told USA Today´s Michelle Healy.

That evidence “only continues to increase as tens of millions of doses have been administered and no evidence of safety concerns has emerged,” said Kahn, who was not involved in the new study.

The study does have some limitations, report the authors. The cross-sectional survey compared three distinct cohorts across multiple years, and the survey focused mainly on self-reporting from parents without verifying vaccination status through providers.

Microbes Found Thriving In Deepest Parts Of Mariana Trench

redOrbit Staff & Wire Reports – Your Universe Online

Despite immense pressure and a lack of sunlight, an abundance of microbes are thriving in the deepest parts of the Pacific Ocean, claims new research published in Sunday´s edition of the journal Nature Geosciences.

A team of scientists led by Ronnie Glud of the University of Southern Denmark explored the 36,000-foot deep Mariana Trench “unusually high levels of microbial activity in the sediments” of the Challenger Deep region, Colin Barras of New Scientist said.

“Glud’s team dispatched autonomous sensors and sample collectors into the trench to measure microbial activity in the top 20 centimeters of sediment on the sea bed,” Barras added. “The pressure there is almost 1100 times greater than at the surface. Finding food, however, is an even greater challenge than surviving high pressures for anything calling the trench home.”

The amount of bacteria and other microbes discovered by the researchers was more than double that discovered at a site nearly half as deep, explained Reuters Environment Correspondent Alister Doyle. They fed upon dead plants and fish that fell into the deepest parts of the trench, Doyle said, supporting a theory which had suggested that those materials fall onto the trench´s steep sides, slide to the bottom and form a sort of “hot spot” for microbes.

“It’s surprising there was so much bacterial activity,” Glud, an aquatic biogeochemist at the Odense, Denmark-based university, told ABC News Australia. “Normally life gets scarcer the deeper you go — but when you go very deep, more things start happening again. We find a world dominated by microbes that are adapted to function effectively at conditions highly inhospitable to most higher organisms.”

Likewise, Hans Røy, a geomicrobiologist at Aarhus University in Denmark who was not a member of the survey team, told Sabrina Richards of The Scientist that the discovery “shows that microbes are basically able to cope with any conditions on this planet.”

The study could also have implications related to climate change, Richards explained. Ocean-dwelling microbes play a key role in the carbon cycle, and if organic matter falls into the ocean without being eaten and digested, it ultimately turns into fossil fuels. However, if microbes consume those substances, they release carbon dioxide and keep the compound cycling in the ocean where they dwell. The question that remains, the researchers say, is: how effective are microbes at breaking down organic particles at such extreme depths?

Glud told Reuters that it is “likely that more carbon is deposited” in the deepest parts of the trench than previously believed. He added that he and his colleague had discovered “a small exotic piece of the puzzle which has never been studied before” when it comes to the how large bodies of water recycle or bury carbon.

James Webb Telescope Support Structure Wing Completed

redOrbit Staff & Wire Reports — Your Universe Online

The massive backplane that will help hold the James Webb Space Telescope´s primary mirror in place as it scans the night sky is now one step closer to completion, NASA officials announced on Friday.

The recent assembly of the primary mirror backplane support structure wing “is another milestone that helps move Webb closer to its launch date in 2018,” said Geoff Yoder, the telescope program´s director at the US space agency´s headquarters in Washington.

The wing assemblies were designed and constructed by aerospace and defense products supplier ATK at their Utah facility, where they are now scheduled to undergo testing. They have 900 separate parts, each of which were made from lightweight graphite composite materials using advanced fabrication techniques, NASA officials explained.

They will enable the mirror — itself built from 18 pieces of beryllium — to be folded and fit within a 16.4-foot fairing on board a rocket. The mirror will then unfold to 21 feet in diameter once the telescope is transported into space. The center section of the backplane was completed last April, and now that the wings have been finished, all that remains is to build the support fixture that will be home to an integrated science instrument module.

Ultimately, technicians will connect the wings and the center to the rest of the observatory.

“We will measure the accuracy down to nanometers — it will be an incredible engineering and manufacturing challenge,” explained Bob Hellekson, ATK’s Webb Telescope program manager. “With all the new technologies that have been developed during this program, the Webb telescope has helped advance a whole new generation of highly skilled ATK engineers, scientists and craftsmen while helping the team create a revolutionary telescope.”

The fully assembled primary mirror backplane support structure will weigh over 2,000 pound and will measure roughly 24 feet by 21 feet, according to the space agency. It needs to be extremely stable so that it does not alter the shape of the primary mirror, as well as hold the instruments in a precise position in relation to the rest of the telescope. Furthermore, according to NASA, when the successor to the Hubble Space Telescope is operating in extremely cold conditions (360 degrees below zero to 406 degrees below zero Fahrenheit), the backplane cannot vary more than 38 nanometers, or about one one-thousandth the diameter of a human hair.

“Our ATK teammates demonstrated the thermal stability on test articles before building the wing assemblies with the same design, analysis, and manufacturing techniques. One of the test articles ATK built and tested is actually larger than a wing,” Charlie Atkinson, the deputy Webb Optical Telescope Element manager for Northrop Grumman in Redondo Beach, California, said. “The mirrors are attached to the wings, as well as the rest of the backplane support structure, so the alignment is critical. If the wings distort, then the mirror distorts, and the images formed by the telescope would be distorted.”

Podcast

Image Credit: Photos.com

A podcast is digital media in a series of related content that is downloaded by a subscription through web syndication or streamed online onto either a computer or mobile device. The word podcast was derived from the terms “broadcast” and “pod,” by the success of the iPod. Most podcasts are streamed or downloaded onto mobile devices such as smartphones and the iPod. The podcast is media transferred to a user’s device, similar to a radio or TV broadcast.

The podcast files are stored and maintained on the distributor’s server as a web feed. The user will have an application known as a podcatcher to access the files. The user can check for updates and download any new files. This can be done automatically. The user stores the files on a computer or mobile device for offline use.

The first application developed for podcast use was the iPodderx, developed by August Trometer and Ray Slakinski. In June 2005, Apple released iTunes 4.9 which supported the use of podcasts. As of September 20, 2005, there were 24 trademark applications containing the word podcast. All were rejected but one, named “podcast ready.”

The different types of podcasts are video, enhanced, and novel.

The video podcast, sometimes referred to as a vodcast, includes video clips and are often web TV series that are distributed as video podcasts. Faster internet speeds have been created and video podcast are becoming more popular by using short clips as part of a longer recording. Websites are being created for the intention of video clips and podcasts only. These video podcasts are being streamed on private and public networks bringing a new level of communication. A video podcast is typically 2 – 9 minutes long and used mainly for video blogs, advertising, amateur films, and journalism.

An enhanced podcast simultaneously displays images with the podcast, like chapter markers, hyperlinks, and artwork synchronized to the program or device. All the media and information should be displayed in the same window at the same time. Schools, universities and businesses are using enhanced podcasts to efficiently present lectures, slide shows, video clips, and other types of media.

A podcast novel is an audio book that combines with the podcast and is delivered to the user in a series. Each episode is delivered over a period of time, and when all episodes have been delivered, the user will have the completed audio book. This can be done automatically by RSS through a website, blog, or other method. These podcasts can be listened to immediately or loaded onto the user’s device and listened to later. Some podcast novels are narrated by one individual, while others use multiple characters and sound effects. Podcast novelists have stated that the extra exposure to their novels lets them build an audience even if the novel is not published; this sometimes helps the author gain recognition and secure publishing deals.

Childhood Depression Linked To Teenage Smoking, Obesity

redOrbit Staff & Wire Reports — Your Universe Online

Children who are suffering from depression have a higher risk of developing cardiovascular disease later on in life, according to new research presented at the annual meeting of the American Psychosomatic Society in Miami, Florida on Friday.

The study, which was prepared by scientists at the Washington University School of Medicine in St. Louis and the University of Pittsburgh, reports teenagers who suffered clinical depression when they were children were more likely than other people their age to smoke cigarettes, suffer from obesity, or lead sedentary lives.

Furthermore, that likelihood was present even if the teens had overcome their depression. The findings suggested depression, even at a young age, could increase the risk that heart problems will eventually surface, they added.

“Part of the reason this is so worrisome is that a number of recent studies have shown that when adolescents have these cardiac risk factors, they’re much more likely to develop heart disease as adults and even to have a shorter lifespan,” first author Robert M. Carney, PhD, a professor of psychiatry at Washington University, explained.

“Active smokers as adolescents are twice as likely to die by the age of 55 than nonsmokers, and we see similar risks with obesity, so finding this link between childhood depression and these risk factors suggests that we need to very closely monitor young people who have been depressed,” Carney added in a statement.

While medical experts have long known adults suffering from depression were more likely to have a heart attack or related cardiac event, it has not yet been established when other risk factors for these ailments — including smoking, obesity and sedentary lifestyle — combine with depression to increase the risk for heart problems.

“We know that depression in adults is associated with heart disease and a higher risk of dying from a heart attack or having serious complications,” Carney says. “What we didn’t know is at what stage of life we would begin to see evidence of this association between depression and these cardiac risk factors.”

The Washington University professor and his colleagues looked at children who had taken part in a 2004 study of the genetics of depression. The study investigators surveyed 201 children with a history of clinical depression and 195 siblings with no such history, as well as 161 unrelated age- and gender-matched children with no history of depression. The average age of the participants was nine at the time of the study.

Seven years later, the researchers surveyed the subjects once again, focusing specifically on the rates of smoking, obesity and physical activity in all three groups. According to Carney, 22 percent of the depressed youngsters were obese by age 16 versus just 17 percent for their siblings and just 11 percent in the unrelated children. He said he and his colleagues discovered similar patterns in the other categories as well.

“A third of those who were depressed as children had become daily smokers, compared to 13 percent of their nondepressed siblings and only 2.5 percent of the control group,” he said. Likewise, the teens who had struggled with depression were also the least physically active, followed by their siblings. The members of the third, control group were the most active, they discovered.

Further analysis and the use of statistical methods eliminated other possible causes for the increased smoking and obesity rates, strengthening their belief depression was the cause of the phenomenon. Depressed children were 2.5 times more likely than their siblings to smoke, and heart disease risk factors were also more common in children who had been depressed — whether or not they still suffered from the symptoms at an advanced age.

“Depression seems to come first,” Carney said. “It’s playing an important, if not a causal, role. There may be some related genetic influences that give rise to both depression and to heart disease, or at least to these types of cardiac risk behaviors, but more study will be required before we can draw any firm conclusions about that.”

Lazarus Project Attempts To Resurrect Extinct Frog

April Flowers for redOrbit.com — Your Universe Online
A team of scientists, led by the University of New South Wales (UNSW), has used sophisticated cloning techniques to revive and reactivate the genome of an extinct Australian frog by implanting a “dead” cell nucleus into a fresh egg from another frog species.
Rheobatrachus silus was a bizarre gastric-brooding frog that swallowed its eggs, brooded its young in its stomach and gave birth through its mouth. The frog species became extinct in 1983.
The Lazarus Project team, however, has been able to recover cell nuclei from tissues harvested in the 1970s and kept in a conventional deep freezer since then. The results of this study have not yet been published, however UNSW Professor Mike Archer spoke about the Lazarus Project this week at the TEDx DeStinction event, as well as his desire to clone the extinct Australian thylacine — the Tasmanian Tiger. The Washington DC event was hosted by Revive and Restore and the National Geographic Society to allow researchers from around the world to discuss progress and plans to “de-extinct” other extinct species, such as the woolly mammoth, dodo, Cuban red macaw and New Zealand’s giant moa. The scientists involved also discussed some of the ethical issues surrounding such de-extinctions. Can such species be reintroduced into the wild responsibly? Should they be reintroduced or even brought back at all? The event was livestreamed to the public.
Over the last five years, the Lazarus Project research team has performed repeated experiments using a laboratory technique known as somatic cell nuclear transfer. Fresh donor eggs were harvested from the distantly related Great Barred FrogMixophyes fasciolatus. The egg nuclei were inactivated and replaced with dead nuclei from the extinct frog. Spontaneously, some of the eggs began to divide and grow into early embryonic stages — tiny balls of many living cells. None of the embryos survived beyond a few days; however, genetic testing revealed the dividing eggs contain the genetic material from the extinct R. silus frog.
“We are watching Lazarus arise from the dead, step by exciting step,” says Archer, the leader of the Lazarus Project team. “We’ve reactivated dead cells into living ones and revived the extinct frog’s genome in the process. Now we have fresh cryo-preserved cells of the extinct frog to use in future cloning experiments.
“We’re increasingly confident that the hurdles ahead are technological and not biological and that we will succeed. Importantly, we’ve demonstrated already the great promise this technology has as a conservation tool when hundreds of the world’s amphibian species are in catastrophic decline.”
Dr. Andrew French and Dr. Jitong Guo, formerly of Monash University, performed the technical work in a University of Newcastle laboratory. They were led by frog expert Professor Michael Mahony and were joined by Mr. Simon Clulow and Dr. John Clulow. Professor Mike Tyler, University of Adelaide, preserved and provided the frozen specimens. Tyler extensively studied both species of gastric-brooding frog — R. silus and R. vitellinus – before they vanished in the wild in 1979 and 1985 respectively.

Organ Transplant Recipient Dies From Rabies Infection

Brett Smith for redOrbit.com — Your Universe Online
The Centers for Disease Prevention and Control (CDC) announced today a Maryland man who recently died of rabies contracted the disease when he received an infected transplanted kidney a year and a half ago.
As a result of this revelation, three other patients who received organs from the same donor are “doing fine,” but have been given rabies shots as a precaution, according to CDC officials.
The doctors who performed the transplant in 2011 said they knew the donor had encephalitis, but didn´t know rabies was the cause. Because the disease wasn´t suspected as the cause of death, doctors involved with the operation didn´t think to test for it.
Although the number of reported rabies cases is fewer than ten, health officials are thinking about changing their approach to testing donors for the disease.
“What we need, looking forward, is a standardized approach when you have encephalitis of unknown cause so very important things like this aren’t missed,” Dr. Matthew Kuehnert, director of the CDC’s Office of Blood, Organ, and Other Tissue Safety, told CNN.
Health officials initially doubted the kidney was the cause of the infection because of the 15-month period between the surgery and the patient´s death. The average length for the incubation of rabies is seldom longer than three months. Several unnamed sources told The Washington Post the recipient died at the Veterans Affairs Medical Center in Washington after being hospitalized for about a month.
The Maryland man died on February 27 and health officials made the rabies diagnosis this month while investigating his cause of death. Upon re-examining the donor’s case, doctors found that person, who was from Florida, had also died of rabies. The CDC said the two viruses were genetically identical, indicating the organ was the source of the Maryland patient´s rabies.
In addition to vaccinating the other organ recipients, the CDC is looking for anyone who might have come in contact with the donor or the recipients to see if they also have rabies.
The incident marks just the third time rabies has been transmitted by transplanting organs, such as a kidney. In 2004, four people in Texas died from rabies that they contracted from a single donor´s tissue. Health records show there have been at least eight cases of contracting rabies through cornea transplants worldwide.
Rabies isn´t the only disease that has been known to be transmitted through organ transplants. In some cases, the recipient already has the same infection, such as hepatitis C, as the donor organ. In other cases, the patient and physicians decide the risk from the infection is less than the risk of not receiving the organ in time.
Although not as rare as contracting it from a donated organ, about five Americans are infected with rabies each year. The virus is most frequently acquired through contact with a bat. Bites from other infected animals, including raccoons and dogs, account for most of the rest. The CDC did not reveal how the Florida individual had contracted the infection.

FDA Launches Probe Into Diabetes Drug Over Pancreatic Cancer Risk

Lee Rannals for redOrbit.com — Your Universe Online

The Food and Drug Administration (FDA) is looking into findings published by a group of researchers suggesting diabetes drugs have a link to pancreatic cancer.

The FDA said it is reviewing unpublished findings that suggest pre-cancerous cellular changes could be associated with specific Type 2 diabetes drugs known as incretin mimetics. These findings were based on examination of a small number of pancreatic tissue specimens taken from patients after they died from unspecific causes.

The agency said it asked the researchers to provide the methodology to collect and study these specimens and to provide the tissue samples so it can further investigate potential pancreatic toxicity associated with the drug.

Drugs in the incretin mimetic class work by mimicking the incretin hormones that the body produces naturally to stimulate the release of insulin in response to a meal. These drugs are used along with diet and exercise to lower blood sugar in adults with Type 2 diabetes.

“This early communication is intended only to inform the public and health care professionals that the Agency intends to obtain and evaluate this new information,” the agency said in a statement. “FDA will communicate its final conclusions and recommendations when its review is complete or when the Agency has additional information to report.”

Questions about the drug and its effects on the pancreas have been raised before, and the drug’s label even contains warnings about the risk of acute pancreatitis. However, researchers at the American Diabetes Association´s (ADA) 69th Scientific Sessions in 2009 concluded that incretin mimetics did not increase the risk of pancreatitis in patients with diabetes.

In February, John Hopkins researchers wrote in JAMA Internal Medicine contradicting the findings in 2009, saying the drugs are associated with an increased risk of hospitalization for acute pancreatitis. They said agents in drugs under the brand names Januvia and Byetta contribute to the formation of lesions in the pancreas and the proliferation of ducts in the organ.

“These agents are used by millions of Americans with diabetes. These new diabetes drugs are very effective in lowering blood glucose. However, important safety findings may not have been fully explored and some side effects such as acute pancreatitis don´t appear until widespread use after approval,” says study leader Sonal Singh, M.D., M.P.H., an assistant professor in the Division of General Internal Medicine at the Johns Hopkins University School of Medicine.

The FDA ensured that patients should still be taking their medicine as directed until they talk to their healthcare professional. Also, health care professionals should be following the prescribing recommendations for drug labels.

First Evidence Of Life Deep Under Oceanic Crust Realized

Lee Rannals for redOrbit.com — Your Universe Online

Scientists writing in the journal Science say they have found the first direct evidence of life in the deeply buried oceanic crust.

Researchers on board the Integrated Ocean Drilling Program’s (IODP) research vessel JOIDES Resolution drilled a water depth of 1.5 miles and hundreds of feet of sediment into the oceanic crust off the west coast of North America. After examining rock samples from this depth, they were able to uncover evidence of life, suggesting this ecosystem is largely supported by chemosynthesis, which is the biological conversion of molecules using oxidation or methane as a source of energy, rather than sunlight like in photosynthesis.

Dr Mark Lever, a scientist at the Center for Geomicrobiology at Aarhus University, Denmark, said they learned that sunlight is a prerequisite for life on Earth. In the photosynthesis process, organisms use sunlight to convert carbon dioxide into organic material. However, life in the rock material in the oceanic crust is fundamentally different.

“There are small veins in the basaltic oceanic crust and water runs through them. The water probably reacts with reduced iron compounds, such as olivine, in the basalt and releases hydrogen. Microorganisms use the hydrogen as a source of energy to convert carbon dioxide into organic material,” explains Dr Lever. “So far, evidence for life deep within oceanic crust was based on chemical and textural signatures in rocks, but direct proof was lacking”, adds Dr Olivier Rouxel of the French IFREMER institute.

Ocean crust covers about 60 percent of the Earth’s surface, making it the largest ecosystem on the planet. Since the 1970s, scientists found local ecosystems, like hot springs, are sustained by chemical energy.

“The hot springs are mainly found along the edges of the continental plates, where the newly formed oceanic crust meets seawater. However, the bulk of oceanic crust is deeply buried under layers of mud and hundreds to thousands of kilometers away from the geologically active areas on the edges of continental plates. Until now, we’ve had no proof that there is life down there,” says Dr Lever.

Although the ecosystem is mostly based on hydrogen, several different forms of life are found in these depths. The hydrogen-oxidizing microorganisms create organic material, forming the basis for other microorganisms in the basalt. Some of the organisms get their energy by producing methane or reducing sulphate.

“We collected rock samples [34 miles] from the nearest outcrop where seawater is entering the basalt. Here the water in the basaltic veins has a chemical composition that differs fundamentally from seawater, for instance, it is devoid of oxygen produced by photosynthesis. The microorganisms we found are native to basalt,” explains Dr Lever.

Laboratory cultures in the study have shown that the DNA belonging to these organisms is not fossil.

“It all began when I extracted DNA from the rock samples we had brought up. To my great surprise, I identified genes that are found in methane-producing microorganisms. We subsequently analyzed the chemical signatures in the rock material, and our work with carbon isotopes provided clear evidence that the organic material did not derive from dead plankton introduced by seawater, but was formed within the oceanic crust,” Lever said.

He added that sulphur isotopes showed the team that microbial cycling of sulphur had taken place in the same rocks.

“These could all have been fossil signatures of life, but we cultured microorganisms from basalt rocks in the laboratory and were able to measure microbial methane production,” says Lever.

Finding life in these harsh environments on Earth could shed light on what kinds of life lives on other planets. Researchers studying microorganisms in Antarctica are finding better examples of what life on Mars and other extreme environments may be like.

Scientists from the University of Maryland reported in the journal BMC Biotechnology recently about how they found new aspects of certain proteins that could enable life to function on Mars. They found significant differences in the core proteins of Antarctic extremeophile bacteria, or Haloarchaea, compared to similar proteins in other microorganisms. These differences allow the extremeophiles to tolerate severe living conditions.

DNA Study Reveals Secrets Of Gentically Similar Polar And Brown Bears

Brett Smith for redOrbit.com – Your Universe Online
A new report in PLoS Genetics attempts to clarify conflicting studies on a population of Alaskan brown bears that are genetically similar to polar bears, yet look and act like typical brown bears.
“This population of brown bears stood out as being really weird genetically, and there’s been a long controversy about their relationship to polar bears,” said co-author Beth Shapiro, a professor of ecology and evolutionary biology at the University of California, Santa Cruz (UCSC). “We can now explain it, and instead of the convoluted history some have proposed, it’s a very simple story.”
Shapiro and her team believe that as the last Ice Age ended and the glaciers receded, a group of polar bears was stranded on Alaska’s Admiralty, Baranof, and Chicagof Islands, collectively known as the ABC Islands. Eventually, male brown bears would swim across to the islands from the mainland and mate with female polar bears living there, transforming the entire ABC Islands´ population into brown bears.
Previous studies on both of these bear species, which have been known to mate and known to produce fertile hybrids, suggested that all polar bears had descended from the ABC brown bears — essentially telling Shapiro´s story in reverse. However, the findings from UC Santa Cruz biologists show that the genetic exchange occurred only in isolated populations and did not affect the larger polar bear population.
Shapiro said previous research had focused primarily on the bears´ mitochondrial DNA, which is inherited directly from the mother´s DNA.
“The key to solving this mystery was to analyze DNA from the ABC Islands bears’ nuclear genomes, and in particular their X-chromosomes,” Shapiro said in a statement. “Focusing on the X gave us a surprising result.”
In the latest study, the team, which included scientists from California, Canada and Russia, analyzed DNA from seven polar bears, an ABC Islands brown bear, a mainland brown bear, and a black bear. The researchers also considered data from recently published bear studies by other researchers.
The team found that polar bears are genetically homogeneous, with no evidence of brown bear ancestry, yet the ABC Islands brown bear DNA contained clear evidence of polar bear ancestry. According to Shapiro, evidence from the bears´ X chromosome indicated that ABC brown bears have more DNA in common with polar bear females than they do with polar bear males.
To better understand the scenario behind these genetic results, the team used computer simulations of various breeding scenarios.
“Of all the models we tested, the best supported was the scenario in which male brown bears wandered onto the islands and gradually transformed the population from polar bears into brown bears,” said co-author James Cahill, a graduate student at UC Santa Cruz.
The researchers warned that the isolation of the polar bear is occurring today as a result of climate change and said there could be far-reaching genetic impacts as a result.
“During a previous ice age, polar bears ranged much farther to the south than they do today, reaching the present-day ABC Islands and Alexander Archipelago,” said co-author Ian Stirling, from the University of Alberta in Canada. “As the climate warmed and ice began to retreat, it is possible that some of the animals began to spend progressively longer on land with reduced access to ice.”
“We see the same sort of thing happening today with polar bears in areas such as western Hudson Bay or the Russian coast, in response to continued climate warming and loss of ice,” he added.

Chinese Study Provides Evidence That Early Birds Had Four Wings Instead Of Two

Lawrence LeBlond for redOrbit.com – Your Universe Online

When you inspect the legs of most birds you will find everything from the knee down is scaly rather than feathery. There is an exception to this rule however. Some birds of prey, such as eagles, have more feathering below the knee extending down to the feet. As for those with scaly legs, it is a remnant of their ancestry, when birds evolved from small two-legged dinosaurs millions of years ago.

For the most part, experts understand this evolutionary process. With forearm construction becoming longer and flatter, they evolved from hollow tubes into flat asymmetrical vanes and eventually became wings. But new evidence coming from China could shake things up a bit. It seems that the scaly hindquarters of our feathered friends were not always leggy in some primitive birds.

Chinese scientists have made a detailed analysis of nearly a dozen four-winged fossil specimens that existed around 130 million years ago. Reporting in the journal Science, this finding provided the first “solid evidence” that some primitive bird species adopted a four-wing body plan instead of the modern fore-wing, hind-leg rule.

The Chinese team of researchers, led by Xiaoting Zheng of China´s Linyi University, said these early birds flew more like a biplane, with hind wings providing added boost in the air. He said that these primitive birds eventually evolved to the more efficient modern look of today.

The 11 birds analyzed come from five different species and most were larger than a modern crow but smaller than a turkey. The fossils were donated by China´s Shandong Tianyu Museum of Nature.

Previously, several fossils have shown that some dinosaurs had large feathers on both their fore and hind limbs, but no examples of a four-winged body plan had been described until now.

Modern birds have two types of feathers: vaned (pennaceous or contoured) feathers that cover the outside of the body, and down feathers that cover the body underneath. The Chinese team found that one type of vaned plumage was neatly preserved in the skeletal fossils they analyzed, along the creatures´ hind limbs.

This discovery suggests that four wings were the norm for at least a short while in the evolutionary scale, and that birds eventually lost the feathers on the hind limbs over time, returning to a more hind-leggy nature.

Xiaoting is not the first scientist to theorize the four-winged display.

EARLIER EVIDENCE

Ornithologist William Beebe in 1915 first suggested that early birds may have passed through a four-wing gliding stage on their way to evolving a true two-winged flying style. His early theory was quite fanciful, but didn´t gain much credence from the scientific community, largely since there was no evidence to back up his claim.

Nearly 90 years later, in 2003, the prolific Chinese dinosaur hunter Xing Xu found an actual four-winged dinosaur he named Microraptor gui. The outlines of the feathers clearly showed signs of wing-like splaying in both its fore and hind limbs. Of course, the feathery wing-like structures were more typically observable as flares rather than actual wings, and may have helped the dinosaur glide like a bi-plane, rather than fly.

Xing, who is also part of the new research team, had gone on to discover other dinosaurs with long leg feathers, including the Anchiornis, Pedopenna and Xiaotingia, which is named after Xiaoting Zheng. That dinosaur only contains one species, zhengi, also named for the Chinese paleontologist.

Xing later theorized that four-winged dinosaurs lost their back feathers before evolving into the two-winged birds of today. However, the 11 specimens that he, Xiaoting and their colleagues recently analyzed offers up rethinking on that earlier belief.

The new specimens include species like sapeornis, confuciusornis, cathayornis and yanornis. All are primitive birds from between 145 and 100 million years ago (during the Cretaceous period) and all had four wings, with long feathers on the hind wings.

DOUBTS

Xing believes the early wings helped in flight, probably by allowing them to turn more easily or giving them more lift. But other scientists who are involved in the evolution of flight are not convinced by Xing´s work.

“[Xing] has basically just taken a punt that because the feathers were stiff, they were probably aerodynamic in function,” Michael Habib from the University of Southern California, told National Geographic´s Ed Yong. “It is a bit of a weak argument.”

Habib said it is possible that the hind feathers, like those found in Microraptor gui, did play some role in gliding or flying, but the smaller plumes of other baggy-legged (feathered) species “might have merely been there because of a developmental quirk.”

If some genes are producing large feathers on the front limbs, “it might not take much to tweak a set onto the hind limbs too,” he explained.

Kevin Padian from the University of California, Berkeley agrees.

Padian noted that nobody has actually completed any proper tests to show if leg feathers were involved in flight. He said these leg feathers would have likely created drag, but may have provided lift if they sat in a flat sheet like the wings of modern birds. Xing has claimed that these feathers were flat and shear-like, but Padian said they were likely flattened as they became fossilized.

Still, Padian applauded the work of Xing and his colleagues. “It´s a great study because it establishes that leg feathers were widely distributed,” he said.

While the findings are pretty darn cool, Xing noted that it´s possible their work could later be falsified or complicated by another new discovery. Xing said that if he discovers early birds or feathered dinosaurs with extensive scales on their feet, it could spell doom for his hypothesis. “But personally, I am quite confident with our scenario.”

WHAT HAPPENED TO THE FEATHERS?

The more pertinent question today is: Why did the leg feathers eventually disappear?

Xing said he believes this occurred because the birds set their two pairs of limbs towards different ends — the front pair was adept for flying and the hind pair would have been better for walking or running. Also, they may have moved from life in the trees to life on the ground or water. Under any of these scenarios, hind-leg feathers would have been more problematic than useful; and eventually they were lost.

Xing said this could be true of other flying animals. He noted that the earliest flying insects tend to have four wings, while some of the most capable modern insects, like flies, only have two wings. The second pair evolved into a pair of gyroscopes called halteres.

“In the early evolution of flight, different animal groups always try to use as much surface as possible,” said Xing of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP). “Once the major flight organ is well developed, the animal just fires the other organs.”

Mark A. Norell, a paleontologist at the American Museum of Natural History (AMNH) in NYC, who was not involved with the work but has been shown the fossils on recent trips to China, said: “The work is most interesting, but I would like to see a denser sampling” before a firm conclusion can be made.

“We´ve known for a while, from Microraptor, about specimens with feathers down to their toes, and with feet already resembling those of modern birds.”

Norell and others in the field said that the rich fossil beds of China have opened a window into the evolution of early flight in dinosaurs and the evolution of modern birds. Until more specimens can be found to confirm this theory, it can only be surmised how long it took for birds to transition from four to two wings.

The Archaeopteryx, a 150-million-year-old specimen from Germany, is sometimes referred to as the first bird. That specimen likely had feathers on its forelimbs, but more recent fossil finds challenge whether it was a bird-like dinosaur or a dinosaur-like bird.

To cover their bases, the Chinese team wrote that, only until now, no examples of the unusual four-wing structure “have so far been reported in [primitive] birds.”

“These days, we are working hard to extract new information from these wonderful specimens and hopefully can produce more interesting results in future,” concluded Xing.

Understanding Obesity And How Brown Fat Cells Form

Enid Burns for redOrbit.com — Your Universe Online

Many of us don’t know the difference between brown fat cells and white fat cells. But researchers at Perelman School of Medicine at the University of Pennsylvania, led by Patrick Seale, Ph.D., are looking at brown fat cells to better understand how they develop.

The researchers believe that the brown fat cell makes heat for the body, which has helped mammals cope with the cold. New theories say the warmth generated in brown fat cells might also be able to help those dealing with obesity and diabetes, among other health conditions.

“Brown fat cells are the professional heat-producing cells of the body,” said Seale, in a statement from the university. “Because of this they are protective against obesity as well as diabetes.” Seale is an assistant professor of Cell and Developmental Biology, and a member of the Institute for Diabetes, Obesity and Metabolism.

Findings of the research are published this week in Cell Metabolism. In addition to Seale and others at the University of Pennsylvania, other contributors to the research include postdoctoral fellow Sona Rajakumari, Ph.D. and Jun Wu from the Dana-Farber Cancer Institute.

During the research, the group found that a protein switch called early B cell factor-2 (Ebf2) determines which developmental path fat precursor cells take. This determines the brown fat cells versus white fat cells.

One of the findings in the research is that the Ebf2 regulates the binding activity of PPAR-gamma, a protein that regulates differentiation of developing cell types. This is the target of anti-diabetic drugs. Ebf2 affects PPAR-gamma cell’s ability to determine if precursor cells go down the white or brown fat cell path. The conclusion is that Ebf2 may alter epigenetic proteins at brown fat genes to expose PPAR-gamma binding sites.

“Brown fat cells are thought to counteract obesity by burning off excess energy stored in lipid, but white fat cells store energy,” the report says. Brown fat cells contain smaller droplets of lipids and the most mitochondria (containing pigmented cytochromes that bind iron) of any cell type. This is the factor that makes these cells brown. A genome-wide study of PPAR-gamma binding regions conducted by Rajakumari looked at white versus brown fat cells. She found that brown cell-specific binding sites also contain a DNA-recognition site for Ebf2 transcription factors. She also found that Ebf2 is strongly expressed only in brown fat cells. When Ebf2 is overexpressed in precursor white fat cells, they matured into brown fat cells.

EBf2 occurs as the earliest protein in the timeline of the development and differentiation of brown fat cells. “Many times the earlier in the developmental stage that a guiding protein is active, the more powerful it is in driving a certain process of differentiation,” notes Seale. “Ebf2 is not really a readily druggable target, but perhaps a protein related to it is.”

The research was funded by the Functional Genomics Core of the Penn Diabetes and Endocrinology Research Center, and a Searle Scholars Award. Co-authors include Hee-Woong Lim and K.J. Won from the Department of Genetics.

Research Shows Twitter Users Band Together In ‘Tribes’

Alan McStravick for redOrbit.com — Your Universe Online

When one hears the word ℠tribe´, an image of a more primitive collection of people gathered into a loose society is often evoked. Here in the US, the mind leaps to our own indigenous population of Native Americans. However, especially when taking into account the actual definition of the word, our misconceptions come off as too simplistic. Tribes and their activities, it turns out, are not relics of a bygone era. And a new collaborative project between researchers at the Royal Holloway and Princeton Universities aims to detail the relevance of a tribe as it pertains to social media.

The definition of a tribe is far broader than many might even consider. They are comprised of groups of people who are connected to an idea, leader and each other. The evidence based study by researchers sought to explore how people have formed into tribe-like communities on social networking sites such as Twitter.

The idea of a tribal mentality online is not new news for Out:Think owner Tim Grahl. In the Think First blog for his site, meant to speak to authors hoping to engage readers and increase personal following, he posits the question, “When people join your tribe, what are they becoming a part of? What is the bigger “idea” behind your work?” Thanks to this most recent study, Mr. Grahl now has documented proof to bolster his assertion of social media tribal formation.

The paper, entitled “Word usage mirrors community structure in the online social network Twitter” was published in EPJ Data Science, and in it, they detail how they found these online communities have a common character, occupation or interest. In many, the development of a unique and distinctive language was even recognized.

“This means that by looking at the language someone uses, it is possible to predict which community he or she is likely to belong to, with up to 80% accuracy,” according to Dr. John Bryden from the School of Biological Sciences at Royal Holloway. “We searched for unusual words that are used a lot by one community, but relatively infrequently by the others. For example, one community often mentioned Justin Bieber, while another talked about President Obama.”

A colleague at the university and on the study, professor Vincent Jansen, added, “Interestingly, just as people have varying regional accents, we also found that communities would misspell words in different ways. The Justin Bieber fans have a habit of ending words in ℠ee´, as in ℠pleasee´, while school teachers tend to use long words.”

In the process of their research, the team devised a map of the online communities. This map detailed how individual communities had vocations, political views, ethnicities and hobbies in common. The map was able to be created due to the team focusing on the sending of publicly available messages through Twitter. This method allowed the team to record conversations between two or many participants.

Once the initial data was collected, the team grouped the users into the mapped communities through the use of cutting-edge algorithms from both physics and network sciences. Specifically, the algorithms sought to identify individuals that tend to send their messages to other members of the same community.

With the team being able to identify and map the social communities, Dr. Bryden made the suggestion that they analyze the language use within each of the communities.

Dr. Sebastian Funk, a study co-author from Princeton University, stated, “When we started to apply John´s ideas, surprising groups started to emerge that we weren´t expecting. One ℠anipals´ group was interested in hosting parties to raise funds for animal welfare, while another was a fascinating growing community interested in the concept of gratitude.”

This innovative and forward thinking research utilized many data collection techniques not used previously. For this reason, the Royal Holloway University has filed a patent application to safeguard their future use.

Intense Terahertz Pulses Cause DNA Damage But Also Induce DNA Repair

Biomedical Optics Express research details how terahertz pulses that destroy skin tissue at the same time increase tumor-suppressing proteins

Terahertz (THz) radiation, a slice of the electromagnetic spectrum that occupies the middle ground between microwaves and infrared light, is rapidly finding important uses in medical diagnostics, security, and scientific research. As scientists and engineers find evermore practical uses for this form of radiation, questions persist about its potential human health risks.

New research performed on lab-grown human skin suggests that short but powerful bursts of THz radiation may both cause DNA damage and increase the production of proteins that help the body fight cancer. The findings, which are the result of a collaboration between physicists at the University of Alberta and molecular biologists at the University of Lethbridge in Canada, are published today in the Optical Society’s (OSA) open-access journal Biomedical Optics Express.

“While these investigations of the biological effects of intense THz pulses are only just beginning,” said Lyubov Titova, with the University of Alberta and a member of the research team, “the fact that intense THz pulses can induce DNA damage but also DNA repair mechanisms in human skin tissue suggests that intense THz pulses need to be evaluated for possible therapeutic applications.”

THz photons, like their longer wavelength cousins in the microwave range, are not energetic enough to break the chemical bonds that bind DNA together in the nucleus of cells. These waves, however, have just the right frequency to energize water molecules, causing them to vibrate and produce heat, which is why microwave ovens are so efficient at cooking food. For this reason, it was believed that heat-related injuries were the principal risks posed by THz radiation exposure.

Recent theoretical studies, however, suggest that intense THz pulses of picosecond (one trillionth of a second) duration may directly affect DNA by amplifying natural vibrations (the so-called “breathing” mode) of the hydrogen bonds that bind together the two strands of DNA. As a result, “bubbles” or openings in DNA strands can form. According to the researchers, this raised the question: “Can intense THz pulses destabilize DNA structure enough to cause DNA strand breaks?”

As shown in earlier animal cell culture studies, THz exposure may indeed affect biological function under specific conditions such as high power and extended exposure. There is, however, a vast gulf between animal research and conclusions that can be drawn about human health.

In a first of its kind study, the Canadian researchers exposed laboratory-grown human skin tissue to intense pulses of THz electromagnetic radiation and have detected the telltale signs of DNA damage through a chemical marker known as phosphorylated H2AX. At the same time, they observed THz-pulse induced increases in the levels of multiple tumor suppressor and cell-cycle regulatory proteins that facilitate DNA repair. This may suggest that DNA damage in human skin arising from intense picosecond THz pulse exposure could be quickly and efficiently repaired, therefore minimizing the risk of carcinogenesis.

The researchers used a skin tissue model made of normal, human-derived epidermal and dermal cells. This tissue is able to undergo mitosis (cell division) and is metabolically active, thus providing an appropriate platform for assessing the effects of exposure to high intensity THz pulses on human skin. For their study, Titova and her colleagues exposed the skin tissue to picosecond bursts of THz radiation at levels far above what would typically be used in current real-world applications. They then studied the sample for the presence of phosphorylated H2AX, which “flags” the DNA double strand break site and attracts cellular DNA repair machinery to it.

“The increase in the amount of phosphorylated H2AX in tissues exposed to intense THz pulses compared to unexposed controls indicated that DNA double strand breaks were indeed induced by intense THz pulses,” observed Titova. Once DNA breaks occur, they can eventually lead to tumors if unrepaired. “This process,” she continued, “is very slow and cells have evolved many effective mechanisms to recognize damage, pause cell cycle to allow time for damage to be repaired, and — in case repair is unsuccessful — to prevent damage accumulation by inducing apoptosis, or programmed cell death of the affected cell.”

The researchers confirmed that these cellular repair mechanisms were taking place by detecting an elevated presence of multiple proteins that play vital roles in DNA repair, including protein p53 (often called “a guardian of the genome”); p21, which works to stop cell division to allow time for repair; protein Ku70, which helps reconnect the broken DNA strands; and several other important cell proteins with known tumor-suppressor roles. These observations indicate that exposure to intense THz pulses activates cellular mechanisms that repair DNA damage. However, the researchers note, it is too soon to make predictions on the long-term implications of exposure.

“In our study we only looked at one moment in time — 30 minutes after exposure,” Titova said. “In the future, we plan to study how all the observed effects change with time after exposure, which should allow us to establish how quickly any induced damage is repaired.”

The Canadian researchers hope to explore the potential therapeutic effects of intense THz radiation exposure to see if directed treatment with intense THz pulses can become a new tool to fight cancer.

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Whales’ Baleen Teeth Entangle Prey With Hairy Fringes

Brett Smith for redOrbit.com – Your Universe Online

Whether they hunt for food by opening their mouths while diving deep into the ocean or skimming along its surface, many whale species rely on their baleen teeth to filter tasty morsels from the mouthfuls of seawater they take in.

According to Alexander Werth, a biology professor from Hampden-Sydney College in Virginia, no one has ever looked into the mechanism behind how the hairy substance actually traps food.

“The standard view was that baleen is just a static material and people had never thought of it moving or that its function would be altered by the flow of water through the mouth,” Werth explained.

Werth found that the baleen system actually works best by entangling food as water flows across it, according to his report in The Journal of Experimental Biology.

Composed primarily of the protein keratin, baleen is a system of large, continually growing plate-like structures with an internal fiber core and a smooth exterior. These plates are continually worn away by the whale´s tongue, forming bristly fringes that are capable of trapping food.

Most whale mouths contain about 300 baleen ℠plates´ and the structure of baleen systems can vary from whale to whale. For example, the hairy baleen fringes of the skim-feeding bowhead whale are twice as long as the fringes on the dive-feeding humpback whale.

According to Werth, he became fascinated with baleen while performing his postdoctoral work with the Inupiat Eskimos of Barrow, Alaska. After collecting baleen samples from ram-feeding bowheads in Alaska, Werth decided to compare them with samples of humpback baleen that he had collected as a graduate student.

He began by trying to see how well the baleen trapped small latex beads carried by flowing water. Taking a small section of each type of baleen, Werth place each sample in a flow tank and watched as he varied the flow of the water from 4 to 47 inches per second. He also changed the inclination of the baleen, allowing the water to flow from parallel to perpendicular.

While making adjustments to his experimental settings, Werth monitored the baleen and recorded how many beads were trapped for 2 seconds or more. He found that the bristles trapped most beads at the lowest speeds. As the flow speed increased, the marine biologist saw the baleen fringes act more like hair, allowing more beads to pass through. This indicated that single baleen plates are less effective filters at higher swimming speeds.

However, Werth said that the results of this set of experiments were inconclusive.

“’It doesn’t make sense to look at flow across a single plate of baleen, it’s like looking at feeding with a single tooth,” he said. “You can’t chew anything with just one tooth, you need a whole mouthful.”

To refine his experiment, Werth built a scale model rack of six baleen plate fragments and tested the larger system for its ability to trap the latex beads. This setup resulted in the baleen becoming tangled and matted at flow speed that closely mirror the average swimming speeds of these whales.

Encouraged by these results, Werth said he plans to scale up his experimental baleen systems to get a more comprehensive picture of how they enable whales to feed.

Study Finds People, Livestock And Carnivores Share Same Space

Michigan State University

In the southern Rift Valley of Kenya, the Maasai people, their livestock and a range of carnivores, including striped hyenas, spotted hyenas, lions and bat-eared foxes, are coexisting fairly happily according to a team of coupled human and natural systems researchers.

“I wouldn´t call the results surprising,” said Meredith Evans Wagner, a visiting scholar from the University of Florida in the Center for Systems Integration and Sustainability (CSIS) at Michigan State University and part of the research team. “Other research has shown that people and carnivores can coexist, but there is a large body of thought that believes carnivores need their own protected space to survive.”

The paper “Occupancy patterns and niche partitioning within a diverse carnivore community exposed to anthropogenic pressures” was recently published in Biological Conservation. Other authors are Paul Schuette and Scott Creel, of Montana State University, and Aaron Wagner, postdoctoral researcher in the BEACON Center for the Study of Evolution in Action at Michigan State.

The paper´s findings echo results of a study published in PNAS in September 2012 by Jianguo “Jack” Liu and Neil Carter of CSIS: namely that tigers and people are sharing the same space in Chitwan National Park in Nepal, albeit at different times.

Wagner and her colleagues spent just over two years documenting the carnivores of the southern Rift Valley, using motion-detecting camera traps to captures images of the creatures and people using four different areas of land: a conservation area with no human settlements, a grazing area that also had no human settlements, a permanent settlement area, and a buffer zone between the grazing and conservation areas that included seasonal human settlements.

While most of the results were expected — the majority of carnivore photos were taken after dark, most of the larger predators, such as lions and spotted hyenas, tended to be found in the conservation area that didn´t include any human settlements — there were some intriguing results.

“We found that while there were more striped hyenas in the conservation area, there were also striped hyenas in the buffer zone, close to the human settlement area,” Wagner explained. “The hyenas weren´t avoiding that area; they were using the settlement area as a resource in addition to hunting.”

When the Maasai slaughtered an animal for food, they throw the scraps out their back doors, which are at the edge of the buffer zone, where the striped hyenas were happy to eat them.

“Carnivores aren´t a problem for this group of Maasai,” Wagner said. “They´ve made a conscious decision to not hunt carnivores. If one of their livestock is killed by a carnivore, people don´t go out and kill a carnivore in retaliation. It´s a little bit unusual in that way. But in our study, we found that carnivores killing livestock didn´t happen a lot.”

“Wildlife is clearly driven away from the permanent settlement areas,” said Aaron Wagner. “But the seasonal human migration out of the buffer zone keeps that area viable for wildlife. Numbers drop when the cattle and people move in, but the striped hyenas seem to have habits that allow them to compensate. They do scavenge around bomas [Maasai settlements] when the pickings are good, but they hunt, too. Even with the people around, there are enough prey left, or enough trickling in from the conservation area, that they have plenty to hunt. More often than not, when following a striped hyena that´s foraging (or playing at a den) at 3 a.m., there´s no indication that people are so close.”

The research was funded by the National Science Foundation, the Cincinnati Zoo and the Panthera Corporation.

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Advanced MRI Technology Could Lead To Earlier Disease Detection

redOrbit Staff & Wire Reports – Your Universe Online

Full-body MRI scans could someday be a regular part of a person´s annual medical check-up, thanks to the efforts of researchers at Case Western Reserve University and University Hospitals (UH) Case Medical Center who are reportedly working on faster and less expensive magnetic resonance imaging technology.

Their efforts, which are detailed in the latest edition of the journal Nature, could lead to full-body scans that could easily detect various types of cancer, heart disease, multiple sclerosis, and other ailments before they become more difficult to treat.

The technology would operate on the basis that each type of body tissue and different types of diseases have unique fingerprints that could be used to quickly diagnose various biological issues, the researchers explained.

By using new MRI-type technology known as magnetic resonance fingerprinting (MRF) to scan for different physical properties at the same time, they were able to discern amongst white matter, gray matter, and cerebrospinal fluid in approximately 12 seconds. Furthermore, they believe that they will eventually be able to do so even faster.

“The overall goal is to specifically identify individual tissues and diseases, to hopefully see things and quantify things before they become a problem,” Dr. Mark Griswold, a radiology professor at the Case Western Reserve School of Medicine, said in a statement. “But to try to get there, we’ve had to give up everything we knew about the MRI and start over.”

MRF technology would reduce the time it takes to get a full-body scan to just minutes while also providing far more information than current MRI equipment. In addition, unlike today´s scans, the MRF readings would not require a radiologist in order to interpret the results, also making them more affordable to patients.

To help explain the difference between MRI and MRF, Griswold compares them to a pair of performing musical groups. “In the traditional MRI, everyone is singing the same song and you can tell who is singing louder, who is off-pitch, who is singing softer, but that’s about it,” he said. “With an MRF, we hope that with one step we can tell the severity and exactly what’s happening in that area.”

In addition to Griswold, researchers working on the enhanced technology include Vikas Gulani, an assistant professor of radiology, and Nicole Seiberlich, assistant professor of biomedical engineering, both of Case Western. The three of them have been working on MRF for a decade.

During the past three years, they have been joined by graduate student Dan Ma, Kecheng Liu of Siemens Medical Solutions, radiologist Jeffrey L. Sunshine of UH Case Medical Center, and Case School of Engineering dean and biomedical engineering professor Jeffrey L. Duerk. During that time, they have proved the concept and developed the technology, and over the next few years, they hope to reduce the scanning time required and continue building the library of so-called biological fingerprints utilized by the MRF scanner.

How We Perceive Movement Through Space And Time Is Directly Connected

redOrbit Staff & Wire Reports – Your Universe Online

From time immemorial, humans have grappled to understand the slippery notion of time, often drawing on familiar metaphors of physical motion such as “time flies” or “time marches on.” When Einstein published his paper on special relativity in 1905, he forever fused the notions of space and time into a single, mind-boggling, yet mathematically elegant, concept known as spacetime. Now, new research on the human brain suggests our movements through physical space are directly connected with how our brains perceive time.

“It seemed to us that psychological scientists have neglected the important fact that, in everyday experience, people don´t evaluate the past and the future in exactly the same way,” explained lead author Eugene Caruso of the University of Chicago Booth School of Business.

In recent years, an array of new research in the field spatial perception has revealed humans feel closer to objects they are moving towards than objects they are moving away from — an illusion that holds true even when the distance of the objects remains exactly the same. Since our perception of time is so closely related to our experience of space, Caruso and his team predicted this same basic principle would hold true for time as well, a phenomenon his team dubbed the ℠temporal Doppler effect.´

By performing a simple survey of people at a train station, the scientists found individuals tended to perceive future times one month or one year away as closer to the present than times one month or one year in the past.

In a separate part of the experiment conducted online, the team found people who completed an Internet survey one week before Valentine´s Day perceived the holiday as being closer to the present than people who were surveyed one week after the holiday.

While these results point to a striking similarity in how we perceive space and time, the team wanted to explore whether there was a direct connection between the two. To do this, they conducted yet another experiment using virtual reality technology.

The team equipped college students with a head-mounted display that placed them in a virtual scene where a two-lane road was lined on both sides with trees, streetlamps and buildings. For half of the students, the virtual environment was made to give them the sensation they were moving forward toward a large fountain at the end of the road. The other half was given the virtual experience of moving backwards, away from the fountain.

Following the virtual reality portion of the experiment, the participants were asked how far away a specific date felt to them — one that was three weeks in the future and another three weeks in the past. The students who had just had the virtual experience of moving forward toward the fountain reported the future felt closer to the past, whereas the students who had moved away from the fountain did not feel the future was closer than the past.

For the second group of students, the mismatch between their physical movement (backward) and the chronological direction of the event (future) in question tended to eliminate the ℠temporal Doppler effect´ — a finding Caruso and his colleagues argue confirms a direct link between our perceptions of time and space. In short, we feel closer to the future because we feel like we´re moving toward it just like the students felt like they were moving physically closer to the fountain.

The researchers also suspect this perceptual alignment isn´t mere coincidence but rather that it serves an important practical function. The laws of physics (as we currently understand them) prevent us from going back in time and changing the past. However, we can directly influence our future. Thus the feeling that future events are closer may provide us with the psychological kick in the pants we need to prepare ourselves to deal with those events.

According to Caruso, “this research is important because the idea of psychological distance is central to theory and research in every subfield of psychology — social, developmental, cognitive, clinical — yet there has been an implicit assumption that distance to the past is the same as distance to the future.”

Caruso also says he and his team would like to continue their research by exploring how the temporal Doppler effect influences our day-to-day lives. For example, is a functional temporal Doppler effect associated with healthy psychological function? Can a weakened sense of the effect lead to problems with depression and an inability to escape from the past? Do people who do not experience the temporal Doppler effect have a hard time making plans and decisions about the future?

“Our work suggests instead that there is a systematic difference in people´s perceptions of distance to the past and the future,” Caruso concluded.

The team´s report was published in a recent edition of Psychological Science, a journal of the Association for Psychological Science.

Men Handle Lack Of Sleep Better Than Women

Michael Harper for redOrbit.com — Your Universe Online
Scientists from Duke University believe that women require more sleep than men. When women don´t get the amount of sleep they need, they may suffer the consequences, both mentally and physically. According to this study, men do not experience the same consequences when they get less sleep than recommended.
The consequences of too little sleep can be quite dangerous for women. According to the Duke scientists, women who skimp on their sleep have a higher risk of developing heart disease, depression or other psychological problems. Under-rested women are also more likely to develop blood clots which could one day lead to a stroke.
In addition to a higher risk of some serious health issues, the Duke scientists claim tired women have higher inflammation markers, meaning they´re likely to be in more pain throughout the day. This has led some news sources to use the headline “Women are grumpier than men.”
“This is the first empirical evidence that supports what we have observed about the role of gender and its effects upon sleep and health,” says Edward Suarez, associate professor in the department of psychiatry and behavioral sciences at Duke and the lead author of the study.
For the study, the Duke researchers studied 210 healthy, middle-aged men and women. These participants did not have any existing sleep disorders, did not smoke, and were not taking any sleep medications. Suarez and his team then used a “standardized sleep quality questionnaire” to measure the quality of sleep of each of the participants. Then the research team took blood samples from each of the participants to search out certain biomarkers associated with heart disease, diabetes, and inflammatory proteins which lead to pain.
“We found that for women, poor sleep is strongly associated with high levels of psychological distress, and greater feelings of hostility, depression and anger. In contrast, these feelings were not associated with the same degree of sleep disruption in men,” said Suarez.
He also said it isn´t the amount of time a woman sleeps which opens her up to risk, so much as how long it takes her to fall asleep.
“Women who reported taking a half an hour or more to fall asleep showed the worst risk profile,” said Suarez.
Sleep expert Dr. Michael Breus suggests that it may be beneficial for women to make up for their lack of rest by taking 25 or 90 minute naps. Naps at any other intervals could leave a lady feeling worse than if they hadn´t taken a nap at all.
One British professor claims that women might need more time under the sheets to repair their multi-tasking brains.
“One of the major functions of sleep is to allow the brain to recover and repair itself,” said Professor Jim Horne, director of the Sleep Research Centre at Loughborough University, England, speaking to the Daily Mail. “During deep sleep, the cortex – the part of the brain responsible for thought, memory, language and so on – disengages from the senses and goes into recovery mode.”
“The more of your brain you use during the day, the more of it that needs to recover and, consequently, the more sleep you need,” added Horne.
Interestingly, this Duke study was published nearly five years ago, yet it seems to be making the rounds once more this week.

A High-Resolution Endoscope As Thin As A Human Hair

Engineers at Stanford have developed a prototype single-fiber endoscope that improves the resolution of these much-sought-after instruments fourfold over existing designs. The advance could lead to an era of needle-thin, minimally invasive endoscopes able to view features out of reach of today´s instruments.

Engineers at Stanford have demonstrated a high-resolution endoscope that is as thin as a human hair with a resolution four times better than previous devices of similar design. The so-called micro-endoscope is a significant step forward in high-resolution, minimally invasive bio-imaging with potential applications in research and clinical practice.  Micro-endoscopy could enable new methods in diverse fields ranging from study of the brain to early cancer detection.

The new endoscope was developed by a team under the direction of Joseph Kahn, professor of electrical engineering at the Stanford School of Engineering. The results were published recently in the journal Optics Express and showcased in the Optical Society of America´s Spotlight on Optics.

Their prototype can resolve objects about 2.5 microns in size, and a resolution of 0.3 microns is easily within reach. A micron is one thousandth of a millimeter. By comparison, today´s high-resolution endoscopes can resolve objects only to about 10 microns. The naked eye can see objects down to about 125 microns.

Light paths

Kahn is best known for his work in fiber-optic communications–the ultra-fast data pipes essential to the Internet and large-scale data centers. His work on endoscopy began two years ago when he and a fellow Stanford electrical engineer, Olav Solgaard, were discussing biophotonics–a field of light-based technologies used in studying biological systems.

“Olav wanted to know if it would it be possible to send light through a single, hair-thin fiber, form a bright spot inside the body, and scan it to record images of living tissue,” said Kahn.

The opportunity and the challenge, Kahn and Solgaard knew, rested in multimode fibers in which light travels via many different paths, known in optics as modes; hence the name, multimode fiber. Light is very good at conveying complex information through such fibers–whether computer data or images–but it gets scrambled potentially beyond recognition along the way.

Kahn devised a way to undo the scrambling of information by using a miniature liquid crystal display called a spatial light modulator. To make this possible, Kahn and his graduate student, Reza Nasiri Mahalati, developed an adaptive algorithm–a specialized computer program–by which the spatial light modulator learned how to unscramble the light. Several years before, Kahn had set world records for transmission speeds using a similar trick to unscramble computer data transmitted through multimode fibers.

Research on the micro-endoscope took an unexpected and fortunate turn when Nasiri Mahalati mentioned seminal work in magnetic resonance imaging (MRI) done by John Pauly, another Stanford electrical engineer. Pauly had used random sampling to dramatically speed up image recording in MRIs.

“Nasiri Mahalati said, ℠Why not use random patterns of light to speed up imaging through multimode fiber?´ and that was it. We were on our way,” recalls Kahn. “The record-setting micro-endoscope was born.”

Confronting the Laws of Physics

In Kahn´s micro-endoscope, the spatial light modulator projects random light patterns through the fiber into the body to illuminate the object under observation. The light reflecting off the object returns through the fiber to a computer. The computer, in turn, measures the reflected power of the light and uses algorithms developed by Nasiri Mahalati and fellow graduate student Ruo Yu Gu to reconstruct an image.

Kahn and his students were stunned to discover their endoscope could resolve four times as many image features as the number of modes in the fiber.

“Previous single-fiber endoscopes were limited in resolution to the number of modes in the fiber,” said Kahn, “So this is a fourfold improvement.”

The result, however, raised a scientific conundrum for the team.

“This meant that, somehow, we were capturing more information than the laws of physics told us could pass through the fiber,” said Kahn. “It seemed impossible.”

The team wrestled with the paradox for several weeks before they came up with an explanation. The random intensity patterns mix the modes that can propagate through the fiber, increasing the number of modes fourfold and producing four times as much detail in the image.

“Previous research had overlooked the mixing. The unconventional algorithm we used for image reconstruction was the key to revealing the hidden image detail,” said Kahn.

The ultimate endoscope

Kahn and team have created a working prototype. The main limiting factor at this point is that the fiber must remain rigid. Bending a multimode fiber scrambles the image beyond recognition. Instead, the fiber is placed in a thin needle to hold it rigid for insertion.

Rigid endoscopes–those used frequently for surgeries– are common, but they often use relatively thick, rod-shaped lenses to yield good images. Flexible endoscopes on the other hand–the kind used in colonoscopies and ureteroscopies–usually employ bundles of tens of thousands of individual fibers, each conveying a single pixel of the image. Both types of endoscopes are bulky and have limited resolution.

A single fiber endoscope such as Kahn´s would be the ultimate minimally invasive imaging system, and has been the focus of intense research in optical engineering over the past few years.

Kahn is not the first to develop a single-fiber endoscope, but in boosting the resolution it is possible now to conceive of a fiber endoscope about two-tenths of a millimeter in diameter–just thicker than a human hair–that can resolve about 80,000 pixels at a resolution of about three-tenths of a micron. Today´s best flexible fiber endoscopes, by comparison, are about half-a-millimeter in diameter and can resolve roughly 10,000 pixels with a resolution of about three microns.
The future

A rigid single-fiber micro-endoscope could enable myriad new procedures for microscopic imaging inside living organisms. These range from analyzing neuronal cellular biology in brain tissue to studying muscle physiology and disease to the early detection of various forms of cancer.

Looking ahead, Kahn is excited about the potential of working with biomedical researchers to pioneer these applications, but being a physicist and an engineer at heart, he is most enthralled by the technical challenges of creating a flexible single-fiber endoscope.

“No one knows if a flexible single-fiber endoscope is even possible, but we´re going to try,” said Kahn.

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New Type Of Retinoblastoma Found In Babies

A team of Canadian and international cancer researchers led by Dr. Brenda Gallie at the Princess Margaret Cancer Centre, University Health Network (UHN), has discovered a new type of retinoblastoma, a rapidly developing eye cancer that affects very young babies— a finding that can immediately change clinical practice and optimize care for these children.

The finding, published online today in Lancet Oncology, is a breakthrough in recognizing that a single cancer gene (an oncogene) drives an aggressive retinoblastoma that starts long before birth in families with no history of the disease, says surgeon Dr. Gallie, an ophthalmologist who is also affiliated with The Hospital for Sick Children (SickKids) and a Professor in the Faculty of Medicine, University of Toronto.

“This research completely challenges conventional thinking and clinical practice,” says Dr. Gallie. “The common type of retinoblastoma is initiated by damage to both copies of the RB1 tumor suppressor gene; the predisposition to this type of retinoblastoma can be inherited, so the other eye of the child and those of infant relatives are at risk to develop tumors. When we remove the eye with a large tumor in very young babies and show it is the new oncogene-driven type of retinoblastoma, there is believed to be zero risk for retinoblastoma developing in the other eye or in other infants in the family. This is a major advance in personalized cancer medicine for these children and families.”

The oncogene-driven tumors are much larger than those anticipated in children with inherited retinoblastoma at the same age. “The earliest diagnosis comes when parents observe a white (instead of black) pupil of the eye, and the doctors listen to their observations and understand the urgency of referral. Sometimes Mom really does know best and clinicians should pay close attention.”

Although less than 2% of unilateral retinoblastoma tumors are driven by the oncogene, the early age of onset predicts that about 1 in 5 babies diagnosed under six months of age actually has oncogene-driven retinoblastoma. “All the babies were completely cured by surgery,” says Dr. Gallie.

“We’ve thought for a long time that all retinoblastoma were caused by loss of the retinoblastoma gene. Our study now reveals that’s not the whole story: a new type of retinoblastoma, with normal retinoblastoma genes, is instead driven by extra copies of a powerful cancer gene, causing the cancer to grow very rapidly long before birth. The average age of diagnosis is four months.”

This study, on which several clinical laboratories collaborated, demonstrates that molecular diagnostics can identify novel malignant diseases that elude traditional microscopic study of tissue. The researchers analyzed more than 1,000 primary unilateral non-familial retinoblastoma tumors to validate oncogene-driven retinoblastoma. The Canadian research team included three UHN Research Institutes; Impact Genetics, Toronto; the B.C. Cancer Research Centre and University of British Columbia, Vancouver; the Cross Centre, Edmonton; The Hospital for Sick Children and the Ontario Institute for Cancer Research. The international collaborators were from the Netherlands, Germany, France and New Zealand.

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Auction Giant eBay Skeptical Of Google Ads Value

Peter Suciu for redOrbit.com — Your Universe Online

Search engine giant Google has branched out into a variety of other businesses since it was founded in 1998. The publicly traded company has acquired businesses such as YouTube, Picnik, Zagat and Motorola Mobility. It has created a mobile operating system with Android and has launched the Chrome web browser that now rivals Microsoft´s Internet Explorer for the world´s most popular way of accessing the web.

But all this was made possible because of Google´s flagship search engine, which was being  used for more than a billion searches every day barely a decade after it first appeared. Google has long been the dominant force in the world of web searches and has accrued a vast fortune on search results. And it has further leveraged the potential of search through its ad networks, which include AdMob and DoubleClick.

However, the value of Google´s main advertising service was called into question this week by a study conducted by e-commerce giant eBay, a company that also happens to be one the biggest Internet advertisers. The online auction site questioned whether the paid search ads on Google that show up to the right of the organic search results were actually worth buying.

“The conclusion: Incremental revenue from paid search was far smaller than expected because existing customers would have come to eBay regardless, whether directly or through other marketing channels,” eBay told sources in an email.

eBay´s study suggests that the people most likely to click through those links were loyal customers who would have likely visited the auction site anyway. This new study was presented this week at an economics conference held at Stanford University.

In the study, eBay removed its paid-search keywords from MSN and Yahoo platforms in the US while retaining them on Google. It found that even without the advertising, users still clicked through as the results appeared on the search engine anyway.

“Advertising expenses account for a sizeable portion of costs for many firms and corporations across the globe. In recent years the internet advertising industry has grown disproportionately, with revenues in the United States alone totaling $31.7 billion for 2011, up 21.9 percent from 2010,” read the report by Thomas Blake, Chris Nosko and Steve Tadelis from eBay.

“Removal of these advertisements simply raised the prominence of the eBay natural search result,” the report added.

This is likely not good news to Google, which generated a reported $46 billion in ad revenue last year, up from about $38 billion the year prior. The search giant has responded that its own research suggests that there are significant increases in clicks as the result of paid search advertising.

“Since outcomes differ so much among advertisers and are influenced by many different factors, we encourage advertisers to experiment with their own campaigns,” a Google spokesperson told the BBC.

While the study suggests that large brands like eBay and online retail giant Amazon.com — those that have traditionally been the biggest buyers of Google paid search ads — may not benefit from the services, it could still be beneficial to smaller companies looking to get some attention.

“With Google ad words, particularly for smaller organisations, it can make a lot of sense because for some of them, their websites aren’t at a stage yet where they have been sufficiently indexed by Google, so they struggle to come up in natural searches for terms,” Dr. Philip Alford, director of the Digital Hub in the School of Tourism at Bournemouth University, told the BBC.

Thus paid search could be a good way for new brands to get some name recognition. However, the high-profile eBay report is likely to have a number of web companies, big and small, reevaluating the size and significance of their online advertising budget.

Citizen Science Valuable, Benefits Marine Research Greatly

Brett Smith for redOrbit.com – Your Universe Online

Mobile technology is enabling people to become productive in ways they never thought possible and recently the scientific community has been looking to tap into that productivity by enlisting citizen scientists.

To see just how reliable crowd-sourced research can be, a group of international scientists decided to check data collected by citizen scientists against information collected using traditional scientific means and found that the amateur-collected data compared quite favorably.

According to the team´s report in the journal Methods in Ecology and Evolution, they compared the results of SCUBA divers with those of professional scientists when it came to measuring the variety of fish species across three Caribbean sites.

The divers surveyed the locations using two standardized methods — the ℠belt transect´ method, used in peer reviewed aquatic studies, and the ℠roving diver technique´, used by the Reef Environmental Education Foundation (REEF) volunteer fish survey project.

“The popularity of SCUBA diving has resulted in monitoring of the underwater environment on a scale that was previously impossible,” said lead author Ben Holt, a marine biologist from the UK´s University of East Anglia (UEA). “For example, the REEF method has been used by volunteers in more than 160,000 underwater surveys across the world. It would have cost many millions of pounds for professionals to have undertaken the same work.”

Over the course of four weeks, 24 divers performed over 140 separate underwater surveys across the three sites. While scientific methods revealed 106 different types of fish, the volunteer technique detected even greater marine diversity, uncovering a total of 137 in the same waters.

“The results of this study are important for the future of citizen science and the use of data collected by these programs,” Holt said in a statement. “Allowing volunteers to use flexible and less standardized methods has important consequences for the long term success of citizen science programs.”

“Amateur enthusiasts typically do not have the resources or training to use professional methodology,” he added. “Our study demonstrates the quality of data collected using a volunteer method can match, and in some respects exceed, protocols used by professional scientists.”

Holt also mentioned that amateur scientists could be valuable in understanding the rapidly changing ecosystems that exist in certain regions.

“For example, Lion fish is an invasive species which was not in the Caribbean until roughly 10 years ago,” he said. “They have now become a real problem in many areas and this invasion has been tracked using volunteer data. Following our study, scientists can have more confidence when using these data to consider the impact of threats, such as invasive species, on the wider natural communities.”

While the results of the study appear promising, Holt warned against placing too much emphasis on citizen-collected data.

“It is important to note that our study does not consider the abilities of the individuals performing the surveys and this is also an important consideration for any large scale biodiversity program. By addressing these issues we can make important steps towards enabling the large pool of volunteer enthusiasts to help professional researchers by collecting valuable data across many ecosystems,” concluded Holt.

Satellites Used To Assist With Agricultural Development

ESA

From 800 km high, Earth-observing satellites are assisting international development organizations with their work in developing countries. Satellites enable objective observations of the status of remote rural areas consistently over space and time.

The Mekong Delta in Vietnam is one of the world´s richest agricultural regions and due to the amount of rice produced there it is often referred to as Vietnam´s ℠rice bowl´. The crop feeds the rest of the country and produces enough to make Vietnam one of the world´s top rice exporters.

But the local agriculture — and, as a consequence, the nation´s economy — is threatened by sea level rise and the subsequent influx of salt water.

In order to identify long-term changes in rice cultivated areas and evaluate the effect of salinity intrusion on these areas, satellite data are being used to create land use and land cover maps for statistical analysis.

This is just one of five service trials within a collaborative project by ESA and the UN International Fund for Agricultural Development (IFAD), which finances agricultural development projects primarily for food production in the developing countries.

The other ESA—IFAD projects include land use, land cover and crop monitoring in Niger, Gambia, Botswana and São Tomé and Príncipe. Specialized European Earth observation service providers are also involved, including Deimos Engenharia (PT), Finnish Geodetic Institute (FI), GAF AG (DE), Geoville (AT) and Sarmap (CH).

The collaboration aims to raise awareness within IFAD about how Earth observation technology can be customized to IFAD activities around the globe. This includes assisting in establishing country strategy plans, assessing food security, managing water and adapting to climate change.

On the African island nation of São Tomé and Príncipe, the biologically diverse rainforest in Obo National Park is under threat from illegal logging. To support IFAD and the local government´s monitoring of logging activities and deforestation, yearly maps of forest cover, types, clear cuts and deforestation are being produced. This service trial supports the overall IFAD project aim to implement more efficient practices in the rural sector.

The five ESA—IFAD service trials follow the success of three pilot trials on rice acreage, inundation areas and land parcels in Madagascar.

“IFAD´s partnership with ESA is timely and relevant since IFAD is focusing on using multi-layered tools and approaches to enhance the analysis, planning, monitoring and evaluation of its investment operations, as well as providing better information to guide decision and policymaking processes,” said Ides de Willebois, Director of IFAD´s West and Central Africa Division.

“As one of the outcomes from these five pilot countries, IFAD expects to have a broader understanding of the added value of using Earth observations services during the various stages of investment operations in measuring project performance to scale up the fight against rural poverty,” he continued.

Looking to the future, the upcoming Sentinel series of satellites being developed under Europe´s Global Monitoring for Environment and Security (GMES) programme will continue to provide operational data to organizations like IFAD.

The Sentinel-2 mission will provide complete coverage of Earth every five days and at a resolution of 10 m. This will be particularly useful for agricultural monitoring and change detection.

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The Curiously Significant Evolutionary Role Of Your Sinuses

April Flowers for redOrbit.com – Your Universe Online

The maxillary sinuses are bulbous pouches on either side of the human nose. They are known for their ability to trap mucus and as well as their role in causing sinus infections. Scientists have long thought that they were an evolutionary relic of our distant past, with little or no present value. However, some researchers believe the maxillary sinuses still play an integral role in the shape and function of the nose.

A new study led by researchers at the University of Iowa has examined faces of African and European origin and concluded that the maxillary sinuses act as a cushion, changing size to make room for the nose. According to the study, the sinuses maximize the primary function of the nose, which is to make air as breathable as possible. For the first time, researchers have explained the anatomical interconnectedness of the maxillary sinuses and the shape of the nasal cavity.

The results of this study were published in the journal The Anatomical Record.

The maxillary sinuses “allow the nose to change shape without affecting other areas of the face,” explains Nathan Holton, a biological anthropologist at the University of Iowa. “When something is under selective pressure like the nose, that´s a good thing.”

Like neighbors sharing a duplex, the nose and the maxillary sinuses share a common wall. And much like those proverbial neighbors, it is important whether the nose and maxillary sinuses are on good terms. To maximize function in relation to the climate where an individual lives, the nose has to be able to assume different shapes and change that shape without shifting around everything else in the face and cranium. In other words, the nose has evolved depending on what type of climate the human population lives in.

When humans live in colder climates, the nose evolved to be narrower and longer to better trap air in the nasal passage. In this manner, the air is warmed and moistened before it enters the lungs. However, put those same humans in a warm climate and the nose evolves to be broader and shorter, transporting the already warm and moist air to the lungs more quickly rather than letting it reside in the nasal passages. In broad terms, this explains the long, narrower, prominent bent of the typical northern European noses as well as the flatter, broader shape of the African nose.

To better understand this anatomical-evolutionary relationship, the team took computer tomography scans of 40 individuals evenly divided between European and African ancestry.  They wanted to understand whether a larger nose would mean smaller maxillary sinuses or vice versa. However, their findings defied expectations.

“What we found is that a bigger nasal volume was associated with a bigger sinus volume in both African and European samples,” Holton explains. “This is best explained as an overall size dynamic. Individuals with a bigger face also have a bigger nasal cavity and bigger maxillary sinuses.”

Concluding that nose shape must play a more pronounced role than previously thought, the research team then mapped the shape of the individuals’ nasal cavities by plotting points at different places in a grid. They found that in faces of similar size, maxillary sinuses in the European-derived subjects were on average 36 percent larger than those of African origin. The reason for this difference, they believe, is that the narrower European noses leave more room for larger maxillary sinus cavities.

“Essentially, by having these sinuses, that´s what allows the nose to change its shape, at least in terms of width and independently from other parts of the face,” explains Holton.

Considering that the nose needed to change according to the climate in which our ancestors lived, this evolutionary adaptability was extremely important in allowing early Homo sapiens to spread out to different geographical regions and climates around the planet — from the sweltering dry heat of Sub-Saharan Africa to the bone-chilling subzero temperatures of northeastern Siberia.

According to the researchers, far from being insignificant and obnoxious vestiges of our past, our maxillary sinuses act as critical “zones of accommodation.”

“Our results suggest that while the sinuses are unlikely to play a direct role in nasorespiratory function, they are important with regard to accommodation of climatically relevant changes in internal nasal shape,” the authors wrote.

Pew Survey Shows Mobile Internet Use Soaring Among Teens

Michael Harper for redOrbit.com — Your Universe Online

The pollsters at the Pew Internet & American Life Project have done it again: They´ve put solid numbers to a fact of modern life that most of us already knew. According to a new survey, a large majority of teenagers have cell phones these days, and many of them own smartphones. But these teens aren´t just using their phones to SnapChat one another — they´re also using them as their primary means to get online.

Pew surveyed just over 800 teens aged 12 to 17 along with their parents. Once complete, the group found that a total of 78 percent of American teens own a cell phone, and almost half of these kids (47 percent) own a smartphone. This number of smartphone wielding teens has grown by leaps in bounds over the past two years. In 2011, just 23 percent of teens reported owning a smartphone. According to the new survey, this number has grown to 37 percent.

Teens still have access to desktop and laptop computers, of course. Pew found that nine out of ten teens have access to one of these computers, though seven in ten say they share these computers with family members. Even though a majority of teens have access to other means of computing, one out of every four teens says they access the web on their cell phone more often than on traditional computers. Unsurprisingly, this number increased most dramatically among teens who have their own smartphones: One half of these teens say they´re more likely to connect to the web on their smart device.

The study also found that boys and girls are equally likely to own some brand of smartphone. However, the girls surveyed for the study were more likely to use their smartphone to connect to the web than their male peers. All told, 34 percent of teen girls aged 14 to 17 said they accessed the web more often from their smartphone than from a traditional computer, compared to only 24 percent of boys in the same age group. And 55 percent of older teen girls say they use their smartphone as their primary means of connecting to the Internet.

The number of teens using mobile devices to access the web gets even larger when tablets are thrown into the mix. According to Pew´s numbers, three in four teens aged 12 to 17 say they access the Internet with some kind of mobile device, including cell phones, smartphones and tablets. Moreover, this is a trend which shows little consideration for socioeconomic status. Kids in lower-income and lower-education houses were only “somewhat less likely” to use the Internet in any capacity, be it mobile or wired. Yet these kids were more likely in some cases to use their mobile devices to surf the web than teenagers from higher-income and better educated families.

“The nature of teens´ internet use has transformed dramatically — from stationary connections tied to shared desktops in the home to always-on connections that move with them throughout the day,” concludes Mary Madden, the senior researcher for Pew Internet Project & Family Life Group.

“In many ways, teens represent the leading edge of mobile connectivity, and the patterns of their technology use often signal future changes in the adult population.”

The current survey follows a similar one conducted last month which found explosive growth in the use of technology in American classrooms.

This Strange Little Melon May Cure Pancreatic Cancer

April Flowers for redOrbit.com – Your Universe Online

A new study from the University of Colorado Cancer Center reveals that bitter melon juice restricts the ability of pancreatic cancer cells to metabolize glucose, thus cutting the cells’ energy source and eventually killing them.

The findings of the study were published in the journal Carcinogenesis.

“Three years ago researchers showed the effect of bitter melon extract on breast cancer cells only in a Petri dish. This study goes much, much farther,” says Rajesh Agarwal, PhD, co-program leader of Cancer Prevention and Control at the CU Cancer Center and professor at the Skaggs School of Pharmacy and Pharmaceutical Sciences.

“We used the juice — people especially in Asian countries are already consuming it in quantity. We show that it affects the glucose metabolism pathway to restrict energy and kill pancreatic cancer cells.”

Argwal became interested in bitter melon juice by connecting the dots of existing research in new ways. Pancreatic cancer is typically preceded by diabetes, and bitter melon juice has been shown to effect type-II diabetes. It has been used for centuries in the folk medicines of China and India to combat diabetes. Argwal and colleagues wondered what would happen if they left diabetes out of the equation and directly examined the link between pancreatic cancer and bitter melon.

Argwal says the result is an “alteration in metabolic events in pancreatic cancer cells and an activation of the“¯AMP-activated protein kinase, an enzyme that indicates low energy levels in the cells.”

Bitter melon also regulates insulin secretion by pancreatic beta cells. The mouse model of pancreatic cancer was fed bitter melon juice after studies of cell cultures were done. Compared to the control group, the mice fed the bitter melon juice were 60 percent less likely to develop pancreatic cancer.

“It´s a very exciting finding,” Agarwal says. “Many researchers are engineering new drugs to target cancer cells´ ability to supply themselves with energy, and here we have a naturally-occurring compound that may do just that.”

Argwal’s team is applying for grants to allow them to continue studying bitter melon in further chemoprevention trials in mouse models of pancreatic cancer.

Burnout And Stress At Work Can Lead To Coronary Heart Disease

April Flowers for redOrbit.com – Your Universe Online

More so than in many industrialized nations, Americans work longer hours, take fewer vacation days and retire later in life. It is not surprising, therefore, that with such demanding careers many experience job burnout expressed as physical, cognitive and emotional exhaustion resulting from stress at work. Previous studies have found that burnout is also related to obesity, insomnia and anxiety.

A new study from Tel Aviv University‘s Faculty of Management and Sackler Faculty of Medicine departments has found a link between job burnout and coronary heart disease (CHD). CHD is the buildup of plaque in the coronary arteries that leads to angina or heart attacks.

The study, conducted by Dr. Sharon Toker and her colleagues – Profs. Samuel Melamed, Shlomo Berliner, David Zeltser and Itzhak Shpira, was recently published in the journal Psychosomatic Medicine.

A 79 percent increased risk of coronary disease was found among those people identified as belonging to the top 20 percent on the burnout scale. Dr. Toker found these results alarming, saying that they were more extreme than the team expected to find. This makes burnout a stronger predictor of CHD than more classical risk factors such as smoking, blood lipid levels, and physical activity.

Common experiences in the workplace are contributing factors to burnout, including high stress, heavy workload and a lack of control over job situations, a lack of emotional support, and long work hours. The wear and tear this causes will eventually weaken the body.

The researchers hypothesized that because burnout has been associated with other cardiovascular risk factors, such as heightened amounts of cholesterol or fat in the bloodstream, it could also be a risk factor for coronary heart disease.

The study consisted of 8,838 apparently healthy employed participants between the ages of 19 and 67 who presented for routine health exams. The participants were followed for an average of 3.4 years as each was measured for burnout levels and examined for signs of CHD. The research team controlled for typical CHD risk factors such as sex, age, family history of heart disease, and smoking.

In all, 93 new cases of CHD were identified during the follow-up, with burn out being associated with a 40 percent increased risk of developing the disease. Participants in the top 20 percent of the burnout scale had a significant chance of increased risk at 79 percent. Dr. Toker predicts that the results would be even more dramatic with an extended follow-up period.

The team says that these results are valuable for preventative medicine. Their healthcare providers can more closely monitor patients who are experiencing burnout for signs of CHD.

Toker warns that once burnout starts, it sparks a downward spiral and becomes a chronic condition. She says employers can prioritize prevention by promoting healthy and supportive work environments and keeping watch for early warning signs. Employees should contribute to their own prevention by making healthy lifestyle choices, such as exercising more regularly; getting seven to eight hours of sleep per night, and seeking psychological therapy if required.

Algorithm Helps Make Cloud Computing More Efficient

Lee Rannals for redOrbit.com — Your Universe Online

A new software system could help reduce cloud computing hardware requirements by 95 percent, as well as help improve performance.

MIT researchers are developing a new system called DBSeer that uses machine-learning techniques to build accurate models of performance and resource demands of database-driven applications.

Barzan Mozafari, lead author on a paper presented at the recent Biennial Conference on Innovative Data Systems Research, said with virtual machines, server resources need to be allocated according to an application’s peak demand. He also said increased demand means a database server will store more of its frequently used data in its high-speed memory. A slight increase in demand could also cause the system to slow down due to too many requests.

DBSeer monitors fluctuations in both the number and type of user requests and system performance and uses machine-learning techniques to correlate the two. This approach helps predict the consequences of fluctuations that do not fall too far outside the range of the training data.

Sometimes database managers are interested in the consequences of large increases in demand. The software uses a model referred to as a “gray box” model that takes into account the idiosyncrasies of particular database systems, making those fourfold and tenfold increases in demand easier to handle.

“We´re really fascinated and thrilled that someone is doing this work,” says Doug Brown, a database software architect at Teradata, in a statement from MIT. “We´ve already taken the code and are prototyping right now.”

He says Teradata will use the team’s prediction algorithm to determine customers’ resource requirements.

“The really big question for our customers is, ℠How are we going to scale?´” Brown says.

He hopes the algorithm will help allocate server resources on the fly. If servers can assess the demands imposed by individual requests and budget correctly, then they will be able to ensure transaction times stay within the bounds set by customers’ service agreements.

According to a report released by the IDC last year, cloud services will be seeing as much as a 41 percent growth over the next four years. The report said spending on IT cloud services around the world will reach $100 billion by 2016, and the compound annual growth rate from 2012 to 2016 will be 26.4 percent.

“The IT industry is in the midst of an important transformative period as companies invest in the technologies that will drive growth and innovation over the next two to three decades,” said Frank Gens, senior vice president and chief analyst at IDC, in a statement on the report. “By the end of the decade, IDC expects at least 80 percent of the industry´s growth, and enterprises´ highest-value leverage of IT, will be driven by cloud services and other 3rd Platform technologies.”

With the growth of the cloud computing industry, it is important for scientists like the MIT team to continue their research into how to make the service work more efficiently; both for the consumer and the service provider.

University Lab Creates Self-Healing Circuits

Enid Burns for redOrbit.com — Your Universe Online

When a circuit goes, depending upon where it was located, you may be in for a nuisance, if not a headache. In the case of your house, you can just go flip the breaker. But for computers and other electronics, those circuits often mean replacing parts, or even the whole device. A team at the High-Speed Integrated Circuits laboratory in Caltech’s Division of Engineering and Applied Science has developed circuits in tiny power amplifiers with a self-healing capability. These self-healing circuits hint at a future where our electronics correct themselves.

The demonstration was shown with amplifiers so small that 76 of the chips — including the self-healing capabilities — fit on a single penny. To show off their power, the team destroyed various parts of the chips by blasting them multiple times with a high-powered laser. The chips automatically developed a work-around, a process that took less than a second.

“It was incredible the first time the system kicked in and healed itself. It felt like we were witnessing the next step in the evolution of integrated circuits,” said Ali Hajimiri, the Thomas G. Myers Professor of Electrical Engineering at Caltech, in a statement from the University. “We had literally just blasted half the amplifier and vaporized many of its components, such as transistors, and it was able to recover to nearly its ideal performance.”

In the future, chips made with self-healing circuitry could recover from problems such as insufficient battery power or total transistor failure.

The team’s work will appear in the March issue of IEEE Transactions on Microwave Theory and Techniques.

Caltech engineers worked on the project in order to give integrated-circuit chips a healing ability somewhat like that of the human immune system. The process gives the chips the capability of detecting and quickly responding to any number of possible assaults. This keeps the larger system working at optimal levels.

The system works to monitor and address issues that come up during operation. “The power amplifier they devised employs a multitude of robust, on-chip sensors that monitor temperature, current voltage, and power. The information from those sensors feeds into a custom-made application-specific integrated-circuit (ASIC) unit on the same chip, a central processor that acts as the ‘brain’ of the system. The brain analyzes the amplifier’s overall performance and determines if it needs to adjust any of the system’s actuators — the changeable parts of the chip,” the statement said.

The chip’s ability to adapt comes from a system that draws conclusions based on the aggregate response of the sensors. “You tell the chip the results you want and let it figure out how to produce those results,” said Steven Bowers, a graduate student in Hajimiri’s lab, and lead author of the new paper. “The challenge is that there are more than 100,000 transistors on each chip. We don’t know all of the different things that might go wrong, and we don’t need to. We have designed the system in a general enough way that it finds the optimum state for all of those actuators in any situation without external intervention.”

It’s still quite some time before the chip might find its way into your computer, but the work from the Caltech team shows promise.

“Bringing this type of electronic immune system to integrated-circuit chips opens up a world of possibilities,” said Hajimiri. “It is truly a shift in the way we view circuits and their ability to operate independently. They can now both diagnose and fix their own problems without any human intervention, moving one step closer to indestructible circuits.”

At-Home Exercise Programs Great Way For Adults To Get In Shape

Lee Rannals for redOrbit.com — Your Universe Online

Not having time to drive down to the gym to work out each day is a popular excuse, but being able to forgo that drive by just popping in a DVD is one way to counter it. A new study looked into how effective home-based DVD exercise programs are.

Researchers tested a home-based exercise program called FlexToBa (flex-toe-bah) aimed at improving flexibility, toning and balance in older adults, finding it to be an effective tool in getting healthy.

The team recruited 307 adults aged 65 and older, half of which who were asked to use the special fitness video at home, and the other who were asked to watch a different video about healthy aging.

The FlexToBa video included several hours of instruction presented over six sessions meant to encourage progressive exercise three times a week over six months. During the videos, the individuals faced new challenges each month helping to keep them engaged and encouraged to build on their achievements.

The participants in the trial were asked to complete daily exercise logs and receive short support telephone calls with exercise tips every other week for the first two months, and then every month.

At the end of the six-month trial, researchers found that those who stayed with the FlexToBa program saw “clinically important” improvements in scores on several tests of physical function, compared to those in the control group. The clinical tests included strength, balance and gait. FlexToBa participants also saw increases in their upper body strength and balance, and were able to maintain their previous level of lower body flexibility.

University of Illinois kinesiology and community health professor Edward McAuley, who led a new study, told redOrbit that people wanting to get into shape should set challenging but attainable goals.

“Doing anything is better than doing nothing and doing something is likely to give you confidence to do more. For older adults coupling aerobic activity (brisk walking) with activities that improve flexibility, strength and balance are likely to reap the greatest physical and mental health benefits,” McAuley said.

The study did not include a diet program because, McAuley said, their goal “was to determine whether we could deliver an exercise program that targeted flexibility, strength, and balance to older adults who typically would not be able to get access to center-based activity programs and to assess such a program´s effects on functional performance.”

He told redOrbit that working out at home not only allows people to cut out that travel time to the gym, but also allows them not to feel self-conscious about exercising due to being overweight or out of shape. McAuley added that working from home is good because “you can exercise whenever it is convenient for you to do so.”

With the hustle-and-bustle of an average working American’s lifestyle, in-home workout DVDs are becoming more-and-more popular. P90X, one at-home program, is extremely popular and the American Council on Exercise (ACE) set out last year to determine just how effective it was.

ACE found that the 90-day, bootcamp-style home exercise program meets or exceeds recognized standards for improving cardiorespiratory fitness.

“P90X is among the most popular of the high-intensity, interval-style home workout exercise programs sweeping the nation, many of which promise to help individuals burn high amounts of calories in a short period of time,” said ACE´s Chief Science Officer, Cedric X. Bryant, Ph.D. “Our study results found P90X offers an effective workout, and, when combined with a sensible eating plan, we believe it can help many individuals achieve their weight-loss and fitness goals in the comfort of their homes.”

Antarctic Cloud Cover Caused Glitch In Tropical Rainfall Model

April Flowers for redOrbit.com – Your Universe Online

One would not assume that cloud cover over Antactica’s Southern Ocean could cause rainfall in Zambia or the tropical island of Java. New research from the University of Washington, however, finds that a phantom band of rainfall just south of the equator that does not occur in reality is caused by poor simulation of the cloud cover thousands of miles farther to the south. This illusionary band of rainfall is one of the most persistent biases in global climate models.

Atmospheric scientists at Washington hope that their results will help explain why global climate models duplicate the inter-tropical convergence zone, a band of heavy rainfall in the northern tropics, on the other side of the equator by mistake.

The results of the study appear in a recent issue of Proceedings of the National Academy of Sciences (PNAS).

“There have been tons of efforts to get the tropical precipitation right, but they have looked in the tropics only,” said Yen-Ting Hwang, a UW doctoral student in atmospheric sciences who found the culprit in one of the most remote areas of the planet.

“What we found, and that was surprising to us, is the models tend to be not cloudy enough in the Southern Ocean so too much sunlight reaches the ocean surface and it gets too hot there,” Hwang said. “People think of clouds locally, but we found that these changes spread into the lower latitudes.”

Prior studies examined tropical sea-surface temperatures, or better ways to represent tropical winds and clouds. None managed to correctly stimulate rainfall in the tropics, however, which is an important region for global climate models since small shifts in rainfall patterns can have huge effects on climate and agriculture.

“The rain bands are very sharp in this area,” commented Dargan Frierson, a UW associate professor of atmospheric sciences. “You go from some of the rainiest places on Earth to some of the driest in [less than a few hundred miles].”

Recent theories have suggested that tropical rainfall might be linked to global processes. The new research looked for possible connections to ocean temperatures, air temperatures, winds and cloud cover.

“For the longest time we were expecting that it would be a combination of different factors,” Frierson said, “but this one just stood out.”

Cloud biases over the Southern Ocean are the primary contributor to the phantom double rain band problem existing in most modern climate models, the research showed.

“It almost correlates perfectly,” Hwang said in a statement. “The models that are doing better in tropical rainfall are the ones that have more cloud cover in the Southern Ocean.”

Hwang will present the findings at the World Climate Research Programme (WCRP) in April. The findings have also been submitted for inclusion in the fifth report of the Intergovernmental Panel on Climate Change (IPCC).

The team found that most modern climate models do not generate enough low-level clouds over the perpetually stormy Southern Ocean, allowing heat to accumulate in the Southern Hemisphere.

“Basically hot air rises, and it rains where air rises. So it´s kind of obvious that the rain is going to be over warmer ocean temperatures,” Frierson said. “Our new thinking is that the heat spreads — it´s the warmth of the entire hemisphere that affects tropical rainfall.”

Climatologists can look for ways to improve the models to increase cloud cover over the Southern Ocean in the short term. Eventually, however, more powerful computers may permit models that are able to create accurate simulations of global cloud coverage.

“We have confidence in climate predictions outside the tropics, but tropical rainfall forecasts are much less certain,” Frierson said. “We hope this work will lead to better rainfall forecasts in regions like equatorial Africa, where it´s so important to have accurate predictions of future patterns.”

Researchers Discover Link Between Sleep Deprivation And Overeating

redOrbit Staff & Wire Reports – Your Universe Online

While previous studies have uncovered a link between a lack of sleep and weight gain, new research published in Monday´s edition of the journal Proceedings of the National Academy of Sciences (PNAS) has discovered the reasons why the phenomenon occurs.

Individuals who sleep just five hours each night over the course of an entire workweek and have unlimited access to food can put on nearly two pounds of weight, the researchers said. They concluded that being forced to stay awake the extra hours required more energy, which in turn led the study participants to consume more food — and to actually eat more than their body needed to keep functioning.

“I don´t think extra sleep by itself is going to lead to weight loss,” lead researcher Kenneth Wright, director of the Sleep and Chronobiology Laboratory at the University of Colorado Boulder, said in a statement. “Problems with weight gain and obesity are much more complex than that. But I think it could help.”

“If we can incorporate healthy sleep into weight-loss and weight-maintenance programs, our findings suggest that it may assist people to obtain a healthier weight,” he added, noting that more study would be required to support that hypothesis. “Just getting less sleep, by itself, is not going to lead to weight gain. But when people get insufficient sleep, it leads them to eat more than they actually need.”

Wright and his associates monitored 16 young, lean, healthy adults at over a period of two weeks. Each study participant slept in a specialized location that allowed the researchers to exert control over the amount of time the subjects slept, as well as monitor how much energy they exerted based on the amount of oxygen they inhaled and the amount of carbon dioxide they exhaled.

For the first three days, each study participant was given the opportunity to sleep nine hours each night and eat portion-controlled meals designed to give them only the amount of calories needed to maintain weight. This was done to establish a baseline measurement, but within a few days, the 16 subjects were split into two different groups. One group was allowed to sleep just five hours for a period of five days, and the other was allowed to continue sleeping for the entire nine-hour period.

“In both groups, participants were offered larger meals and had access to snack options throughout the day ranging from fruit and yogurt to ice cream and potato chips. After the five-day period, the groups switched,” the university explained. “On average, the participants who slept for up to five hours a night burned 5 percent more energy than those who slept up to nine hours a night, but they consumed 6 percent more calories.”

Wright and his colleagues also observed that those who slept for just five hours were more likely to eat smaller breakfasts and then binge on after-dinner snacks. In fact, the researchers said, the total amount of calories of those nighttime snacks were higher than the caloric content of any of the regularly scheduled daily meals — a discovery that they believe helps demonstrate that nocturnal overeating could contribute to weight gain.

The study also detected differences in the way men and women responded to having access to unlimited quantities of food. Even with full nights of sleep, male subjects were more likely to gain weight when they could eat as much as they want. Females, on the other hand, tended to just maintain their current bodyweight when they were allowed to sleep for nine hours, no matter how much they were allowed to consume. Both genders gained weight when they were only allowed to sleep for a maximum of five hours each night, however.

Bioengineering Tooth Replacements

Lee Rannals for redOrbit.com — Your Universe Online

A new technique developed by an expert in craniofacial development and stem cell biology at King’s College London and his colleagues offers up a new type of tooth replacement.

The scientists wrote in the Journal of Dental Research about how they developed a new method of replacing missing teeth with a bioengineered material enervated from a person’s own gum cells.

Current methods for replacing teeth fail to reproduce a natural root structure, leading to loss of jaw bone due to eating and other jaw movements. This new way of bioengineering teeth with gum cells aims to put an end to this problem.

“What is required is the identification of adult sources of human epithelial and mesenchymal cells that can be obtained in sufficient numbers to make biotooth formation a viable alternative to dental implants,” said Professor Paul Sharpe, lead researcher on the project.

During the research, the team isolated human gum tissue from patients at the Dental Institute at King’s College London, and then grew more of it in the lab. After this, they combined the tissue with the cells of mice that form teeth. By translating this combination of cells into mice, the team was able to grow hybrid human and mouse teeth containing dentine and enamel.

“Epithelial cells derived from adult human gum tissue are capable of responding to tooth inducing signals from embryonic tooth mesenchyme in an appropriate way to contribute to tooth crown and root formation and give rise to relevant differentiated cell types, following in vitro culture,” Sharpe said. “These easily accessible epithelial cells are thus a realistic source for consideration in human biotooth formation. The next major challenge is to identify a way to culture adult human mesenchymal cells to be tooth-inducing, as at the moment we can only make embryonic mesenchymal cells do this.”

Scientists are using bioengineering to do some amazing things in health research. In 2011, scientists at the Children´s Center for Cancer and Blood Diseases and The Saban Research Institute of Children´s Hospital Los Angeles said they found a protein to fight leukemia. After bioengineering this protein into purified liquid form, they were able to see how it bonded to leukemia cells and caused their destruction within 24 hours. The protein, CD19-L, even killed leukemia cells that were highly resistant to both standard chemotherapy drugs and radiation. The team is now working to evaluate this new agent for clinical potential against leukemia and to confirm in preclinical studies that leukemic cell destruction can be achieved at non-toxic dose levels.

“The CD19-ligand offers a previously unrecognized defense system against leukemia and opens a new range of therapeutic opportunities for the treatment of leukemia,” said Stuart Siegel, MD, director of the Center for Cancer and Blood Diseases at Childrens´ Hospital Los Angeles.

CDC Traces Salmonella Outbreak To Aquatic Pet Frogs

Brett Smith for redOrbit.com – Your Universe Online

According to a new report from the Centers for Disease Control and Prevention (CDC), an outbreak of Salmonella infections from 2008 to 2011 was caused by small, aquatic pet frogs.

“This was the first Salmonella outbreak associated with aquatic frogs, and in this case the frogs are often marketed as good pets for kids,” lead author Shauna Mettee Zarecki, a public health advisor“¯with the CDC in Atlanta, told Reuters.

The researchers found that the bacterial outbreak affected 376 people in 44 US states and 29 percent of those affected sought treatment. Children were the most heavily affected by the outbreak, leading CDC officials to reinforce safety precautions surrounding the handling of aquatic pets.

“The majority of people didn’t realize there were any risks from these amphibians or other amphibians, like turtles and snakes,” Zarecki said.

“Amphibians and reptiles should never be kept in homes with children less than 5 years old or with people who have immune deficiencies,” she said, adding that humans can become infected after touching the animals or cleaning their areas.

In the new report, federal, state and local health officials investigated a rash of Salmonella infections, mostly among children, in 2008. By early 2009, the outbreak had subsided before the researchers could find the source. The investigation was reignited when five more children were infected in Utah later that year.

The research team interviewed people who were infected with the particular strain of Salmonella from January 2008 through December 2011, asking them what animals and food they were exposed to just before getting sick.

An analysis of the data found that 67 percent of those affected were exposed to a specific kind of frog during the week before their illness — an African dwarf frog.

“Everything really linked these frogs with the illnesses,” Zarecki said.

The officials were able to trace the frogs back to a breeding facility in Madera County, California. An inspection of the facilities turned up the same strain of the bacteria in the facility’s equipment and drains. The facility´s owner shut down operations, enacted a full-scale cleaning program, and re-opened by June 2011.

However, since the frogs can live up to 20 years, CDC officials warn that many contaminated frogs may still be out there.

“Although [African dwarf frogs] are often purchased from pet stores, they are increasingly found at fairs, festivals, and novelty, education, and toy stores and are marketed as good pets for young children or school classrooms,” the researchers noted in their report.

Nicholas Saint-Erne, a veterinarian for PetSmart, Inc., responded to the report by emphasizing safety measures that should be taken when handling certain pets.

“The important consideration with any aquatic pet is to provide adequate filtration to keep the water clean and perform regular partial water changes,” he told Reuters Health in a statement.

Despite the efforts to raise awareness, contracting Salmonella from aquatic pets continues to be a problem for the public. Previous studies have shown that reptiles and amphibians are responsible for about 74,000 Salmonella infections annually in the US.

Antibiotic-Resistant Superbugs A Growing Global Health Threat

Lawrence LeBlond for redOrbit.com – Your Universe Online

Climate change, terrorism and cyber-crime are all issues that are a dire threat to a nation, and now Britain´s top health official says that “superbugs” should be added to that list. The danger posed by the growing number of bacteria resistant to antibiotics is as dangerous to the country as other top threats.

Professor Dame Sally Davies, chief medical officer for England, warned that routine operations could become deadly in as little as 20 years if doctors and surgeons lose the ability to fight dangerous infections, describing the problem as a “ticking time bomb.”

She is urging the government to raise the issue when it meets at next month´s G8 Summit in London.

Davies said that if we do not find a way to fight back against superbugs now, it may be too late in the future. We may not be capable of providing safe cancer treatments and organ transplants; it will be like we are falling back to a “19th century environment,” she said.

She said a global action plan is needed to fill a drug “discovery void” by researching and developing new medicines to treat emerging, mutating infections. Antibiotics are failing and new bacterial diseases are on the rise, Davies noted. While hospitals have been able to get somewhat of a handle on MRSA and C difficile, there is an alarming increase in other bacteria including new dangerous strains of E coli and Klebsiella, which causes pneumonia.

These “gram negative” bacteria, which are found in the gut rather than on the skin, are highly dangerous to older people and those with weakened immune systems. Few antibiotics are effective in treating these strains and that number grows smaller all the time. Davies noted that nearly 5,000 people die each year in the UK due to gram negative sepsis, mainly because the bacteria is resistant to antibiotics.

Davies said pharmaceutical companies need to be encouraged to develop new antibiotic drugs. Currently, many pharms do not view antibiotic manufacturing as a profitable business, which could have dire implications if necessity cannot find a way to override those views.

“We haven’t had a new class of antibiotics since the late 80s and there are very few antibiotics in the pipeline of the big pharmaceutical companies that develop and make drugs,” she said, noting that the Innovative Medicines Initiative — an EU-funded body whose aim is to promote the development of new medicines — should be taken more seriously by drug makers.

SUPER SUPERBUGS

But even as alarming as an increase in antibiotic-resistant bacteria has become, it is even more alarming that new cases of total drug resistant tuberculosis and a new wave of “super superbugs,” ones with a mutation called NDM 1, are starting to show up all over the world.

And the World Health Organization (WHO) recently reported that an untreatable superbug strain of gonorrhea was spreading around the world.

The WHO also states that 150,000 deaths per year are due to multi-drug resistant tuberculosis

“We haven’t as a society globally incentivized making antibiotics. It’s quite simple – if they make something to treat high blood pressure or diabetes and it works, we will use it on our patients everyday. Whereas antibiotics will only be used for a week or two when they’re needed, and then they have a limited life span because of resistance developing anyway,” said the WHO in a statement.

As far as MRSA (methicillin-resistant Staphylococcus aureus) is concerned, there has been an 85 percent reduction in the number of cases throughout the world, thanks in part to increased awareness. At most, large hospital networks now only see a few cases of MRSA per year.

However, for every case of MRSA, there exists 50 to 100 cases of gram-negative bacterial infection, according to Professor Mike Sharland of St. George´s Hospital in London.

“This is your own gut bugs turning on you,” he expressed. “Between 10 percent and 20 percent are resistant to drugs. We do not yet know why they are on the rise, although some hospital procedures, such as the use of catheters, may be implicated. Many are in the very young or older population.”

Davies said the government needs to treat the new wave of superbugs as seriously as they treated MRSA when that was a major health threat. She said for a measure to work, all areas of the government need to be on board, including the Dept. of Environment and Food and Rural Affairs.

Davies said there needs to exist ways to incentivize the pharmaceutical industry to invest in finding and developing new antibiotics. Most companies have given up the hunt because despite their long-winded efforts, resistance continues to develop.

The EU´s Dept. of Health said it would publish a five-year action plan to tackle the health crisis raised in Davies´ report, which will include measures to ensure the drugs are prescribed only when needed.

GLOBAL ACTION

The report, which lists 17 recommendations on tackling the superbug crisis, has received applause from experts in the field. However, one expert says the UK does not have the resources to fight this war on its own.

Richard James, former director of the center for healthcare at the University of Nottingham, said that global action is vital, especially in areas where antibiotics are over-used, wrongly used and in some countries — particularly southern Europe — can be bought over-the-counter.

“Anyone reading the report will realize that there are no magic bullets,” he told The Guardian´s Sarah Boseley. “The majority of the 17 recommendations relate to actions in the UK alone but there is acknowledgment of the requirement for the UK government to campaign for this issue to be given higher priority internationally.”

James suggested that the government should explore the use of a tax on antibiotic use and also enlist a measure to encourage the development of alternatives (vaccines, etc.) by small biotechnology companies and universities.

Laura Piddock, professor of microbiology at Birmingham University and director of Antibiotic Action, said Davies was taking the right track drawing political attention to the antibiotic discovery void.

“However, there are an increasing number of infections for which there are virtually no therapeutic options, and we desperately need new discovery, research and development; the UK is extremely well-placed to do basic discovery and research for new antibacterial molecules,” said Piddock.

The Association of the British Pharmaceutical Industry (ABPI) also applauded Davies´ report.

“Antimicrobial resistance is a serious and growing problem,” said ABPI chief executive Stephen Whitehead. “There are, however, pharmaceutical companies actively involved in researching and developing new antimicrobial medicines. But more still needs to be done and we believe that for there to be a continual supply of effective antibiotics, a comprehensive review of the R&D [research and development] environment and good stewardship are required urgently.”

Nigel Brown, president of the Society for General Microbiology, agreed Davies´ was right to call for an urgent action plan. He said members of his group would work harder to better understand infectious diseases, reduce transmission of antibiotic resistance and help develop new antibiotics.

“The techniques of microbiology and new developments such as synthetic biology will be crucial in achieving this,” he told Reuters´ Kate Kelland.

Davies is not the first chief medical officer in the UK to draw attention to the antibiotic crisis.

In 2008, her predecessor, Liam Donaldson, urged doctors not to use antibiotics to treat colds because they are caused by viruses and do not respond to antibiotics. And in 1999, Sir Kenneth Calman made a similar plea, saying the public had a responsibility not to demand antibiotics.

Tropical Forests May Be Resilient To Effects Of Climate Change

redOrbit Staff & Wire Reports – Your Universe Online

Tropical forests may be more resistant to the effects of greenhouse gas emissions than previously believed, according to a new study published online this week in the journal Nature Geoscience.

In what Olive Heffernan of Nature refers to as “the most extensive study of its kind,” researchers from the US, the UK, Australia and Brazil created a simulation of the impact that carbon-based emissions would have on tropical forests in the Amazonia/Central America region, Asia and Africa through the year 2100.

“They compared the results from 22 different global climate models teamed with various models of land-surface processes. In all but one simulation, rainforests across the three regions retained their carbon stocks even as atmospheric carbon dioxide concentration increased throughout the century,” she added.

According to Reuters reporter Nina Chestney, the only region in which the team discovered forest cover loss was in the Americas (aka the Amazonia/Central America region).

The simulation that predicted a biomass loss in that area was developed by the UK Met Office’s Hadley Centre, a climate change research center located in Exeter, Heffernan explained.

While the study said that there was still some uncertainty in determining exactly how different ecosystems will respond to climate change, lead author Chris Huntingford of the UK´s Centre for Ecology and Hydrology told Chestney they determined that there was “evidence of forest resilience” in all three regions.

“The big surprise in our analysis is that uncertainties in ecological models of the rainforest are significantly larger than uncertainties from differences in climate projections,” Huntingford said in a statement. “Despite this we conclude that based on current knowledge of expected climate change and ecological response, there is evidence of forest resilience for the Americas (Amazonia and Central America), Africa and Asia.”

“This study highlights why we must improve our understanding of how tropical forests respond to increasing temperature and drought,” added co-author Dr. David Galbraith of the University of Leeds. “Different vegetation models currently simulate remarkable variability in forest sensitivity to climate change. And while these new results suggest that tropical forests may be quite resilient to warming, it is important also to remember that other factors not included in this study, such as fire and deforestation, will also affect the carbon stored in tropical forests.”

What is a Rainforest?

Hi, I’m Emerald Robinson, and in this “What is” video, we’re going to discuss our earth’s rainforests.

The definition of a rainforest is straightforward: it’s a densely wooded area that receives a lot of rain fall. Rainforests are one of earth’s biomes, that is, a rainforest is a community of plants and animals that live in a specific climate.

Tropical rainforests are the most common kind of rainforests. Located near the earth’s equator, tropical rainforests rarely get below 60 degrees Fahrenheit, average over 66 inches of rain per year, and stay at about 80 percent humidity.

Scientists who study tropical rainforests divide them into four layers.

The emergent layer consists of the tallest trees, and is inhabited by large birds of prey, bats, and butterflies;

The canopy layer is the thickest layer, made up of the tops of most trees. It’s home to the greatest number of birds and animals;

The understory is the “middle” layer. Found between the canopy and the ground, it’s populated by large cats, snakes, and lizards.

The forest floor, which gets about 2% of the sunlight, makes up the bottom layer. Many of this layer’s animals and plants get nutrition from consuming dead plant and animal matter.

Although most people think of the tropics when they envision a rainforest, there is another kind of rainforest. Temperate rainforests are found in places like the Pacific Northwest of the United States, the British Isles of Europe, and in parts of Australia and New Zealand. These areas are still very wet, but are much cooler, with average temperatures between 40 and 55 degrees Fahrenheit.

Rainforest biomes harbor an enormous diversity of plant and animal life. Unfortunately, human destruction of the rainforest is threatening many species with extinction. For this and many other reasons, scientists and other groups continue to work to protect our precious rainforests.

Scientists Raise Concerns Over Tsunami Debris Carrying Invasive Species

redOrbit Staff & Wire Reports – Your Universe Online
Two years after the earthquake and tsunami that devastated Japan, researchers in the US and Canada are concerned about the possible damage that could be caused by invasive species that have found their way to North America on debris resulting from the 2011 disaster.
According to UPI, experts in the northwest US and Canada are having difficulty determining whether or not marine life washing ashore on the debris will be a threat to the environment and/or living things native to the region — or for how long they could pose a threat.
“Ecologists have a terrible track record of predicting what introduced species will survive and where. But once things are here, they are a threat,” John Chapman, an invasive species expert working at the Oregon State University (OSU) Hatfield Marine Science Center, told Lori Tobias of The Oregonian on Thursday. “They could explode at any time. It’s just like roulette. Each time something lands here, we pull the trigger. We’re getting more and more every year.”
Chapman and his OSU colleagues have been tracking and studying the debris since shortly after it began arriving on nearby beaches. That includes a dock that arrived on Agate Beach in Lincoln County, Oregon last summer following roughly 450 days adrift in the Pacific Ocean. Chapman explained the debris and the organisms they have found living on it have been extremely unpredictable.
“It’s been a constant surprise,” he told The Oregonian. “There was a huge diversity of organisms. There are multiple generations. They were carrying on with life like fleas on a dog’s back. The other thing that was maybe even a bigger surprise is that lots of things settled on the debris after the tsunami. We know that because it was on top of the things that were there at the time of the tsunami.”
For now, Chapman and his colleagues have to measure the debris as it washes in, keeping careful track of the types of species they harbor. He called it a “giant“¦ terrible experiment that should have never happened,” adding, “I can’t see the dock and debris and know what happened in Japan and not feel an enormous amount of responsibility for pulling everything good out of it I possibly can.”
Experts in Canada are faced with a similar situation, according to CTV British Columbia reports published Saturday.
“Items like home cleaning supplies and kids´ toys are now littering West Coast shorelines,” they explained. However it is the “small organisms attached to the debris” that are concerning scientists. “Foreign plants and animals could devastate local ecosystems, researchers say, and as coastal communities“¦ start to see more debris there is growing concern they won´t be able to clean it up fast enough.”
Dolf DeJong, vice president of conservation and education at the Vancouver Aquarium, told reporters invasive species were “a legitimate threat” to the province´s ecosystem.
DeJong warned, depending on exactly which organisms managed to survive and how many there are on any given piece of debris, they could adversely impact the region´s biodiversity, damage the oceans, and even have a negative fiscal influence by harming populations of economically-important life forms like shellfish.
“Canadian researchers say they haven´t had the chance to study the problem as closely because they haven´t had access to such a large item with so many organisms on it,” CTV said, adding that DeJong is urging anyone who spots a foreign object that has washed ashore to contact the aquarium or another expert so they “can determine whether it harbors invasive species.”

Passing Asteroid Will Be Broadcast Live By SLOOH Today

Lee Rannals for redOrbit.com — Your Universe Online

An asteroid about the size of a city block will be making its way past Earth later today, and Slooh plans on giving the world access to its tools to view the near-Earth object (NEO).

Slooh, a leader in live, celestial event programming, said in a statement earlier this week that it will be broadcasting the asteroid 2013 ET on Saturday (Mar 9) as the it passes by Earth at about 2.5 times the Moon’s distance from us.

2013 ET was first discovered on March 3, 2013 by the Catalina Sky Survey, and astronomers believe it is between 210- and 460-feet wide. Slooh said at its maximum brightness, the asteroid will have a magnitude of 17, which is not bright enough to view through a backyard telescope. So, for anyone hoping to catch a glimpse of the NEO, Slooh could be a great option.

“We only have a short viewing window of an hour or so from our Canary Islands observatory on March 9th, but we wanted to give the general public a front row seat to witness this new asteroid in real time as it passes by Earth,” said Slooh president Patrick Paolucci.

2013 ET will be rushing through space at a velocity of 26,552 MPH, which is 15 times faster than a bullet barreling out of a rifle. According to Slooh, if the asteroid were to strike Earth, it could create enough damage to destroy a small city.

“The recent flurry of asteroidal close calls and near misses, including the double whammy of DA14 and the Siberian meteor on February 15th, is starting to make our region of space seem like a video game or pinball contest,” said Astronomer Bob Berman, columnist and contributing editor of Astronomy magazine. “This latest interloper arrives just as serious debates are unfolding as to the obvious need for more and better monitoring of potentially hazardous asteroids crossing our orbit — and even whether we should develop a ℠deflection´ system.”

The asteroid will not be the only big celestial event taking place in our skies this weekend. Comet PANSTARRS will be making its appearance in the Northern Hemisphere finally this weekend, just above the horizon. Scientists believe this comet will shine as brightly as the stars in the bowl of the Big Dipper or Orion’s belt. This comet will no longer be seen in the evening sky by the end of March, but it will be visible just before sunrise.

Perhaps the main event for backyard astronomers this year will be comet ISON. This November comet has the potential to become as bright as the moon, and possibly may even be seen during the daytime hours.

Below is Slooh’s live broadcast of tonight’s asteroid as it passes by. The show will begin at 3:45 eastern time.

Deadly SARS-Like Coronavirus Could Strike US, Warns CDC

redOrbit Staff & Wire Reports – Your Universe Online

The deadly new virus that has caused 14 people to fall ill and resulted in eight fatalities to date, has yet to infect anyone in the US. But that hasn´t stopped the US Centers for Disease Control and Prevention (CDC) from issuing a preemptive warning to state and local health officials.

While most cases of the novel coronavirus have been linked to the Middle East, three recently-confirmed cases (including one death) in the UK demonstrate the virus — which had previously not been seen in humans — can be transmitted from one person to another, the CDC warned Thursday in its Weekly Morbidity and Mortality Report.

Previously, it had been believed the virus could only be transferred to humans from an animal, explained Michael Smith, North American Correspondent for MedPage Today. In addition, the first confirmed UK fatality has also led the American health organization to conclude there can be a co-infection with both the coronavirus and a second pathogen (influenza A) and that there is a mild illness associated with the infection.

According to Mail Online, the CDC has concluded the UK cases of the virus originated with a 60-year-old man who developed a respiratory illness after traveling to Pakistan and Saudi Arabia in January. Samples showed he had contracted both the coronavirus and the H1N1 swine flu.

“This man subsequently passed the infection to two members of his household: a male with an underlying illness who became ill on February 6 and subsequently died; and a healthy adult female in his household who developed a respiratory illness on February 5, but who did not need to be hospitalized and has recovered,” the newspaper reported.

The CDC advises anyone who has visited the Arabian Peninsula or surrounding countries and, within 10 days of their return, is showing signs of severe acute lower respiratory illness to see a doctor immediately. They added doctors should be vigilant of patients who develop unexplained infections shortly after visits overseas.

Currently, the CDC is not issuing any travel restrictions, but are advising those who do wish to travel to the Middle East and neighboring countries to remain vigilant. Symptoms associated with the coronavirus include coughing, fever, and shortness of breath.

“The novel virus, which is associated with severe respiratory illness with renal failure, was first recognized last September and caused alarm because it is genetically and clinically similar to the SARS virus, which caused hundreds of deaths worldwide,” Smith wrote.

“The two most recent cases — both reported from Saudi Arabia — ended in death, bring [sic] the total number of fatalities associated with the virus to eight, including five in Saudi Arabia, two in Jordan, and one in the UK,” he added.

Really Good Vibrations: Study Uses Sex Toy To Loosen Up Singers’ Vocal Chords

Lee Rannals for redOrbit.com – Your Universe Online

Vibrators are being used by researchers at the University of Alberta to help give actors a little bit more vocal power. The team of researchers found that pressing the sex toys against the throats of actors helps to give them improved projection and range — vocally, of course.

“You can actually watch on a spectrograph how vocal energy grows,” said David Ley, who worked on the project. “Even when you take the vibrator off, the frequencies are greater than when first applied.

He said he has used this method with singers, schoolteachers and actors, and so far the vibrator technique has always worked.

Another method used in speech pathology involves massaging the larynx to loosen up tension, but Ley says some people can’t handle this technique because of the feeling of fingers on their throat. He began to search for a new method to help actors and singers project their voices with increased power.

Ley headed over to a local love shop in search of some hand-held vibrators in order to test out whether they could help release various forms of muscular tension. He was looking for a vibrator with a frequency somewhere between 100 and 120 hertz, which is close to the range of the human voice. Once he applied the vibrator to an actress’ neck over the vocal cords, she was able to produce striking results.

“Not only did it free tension in the laryngeal muscles, but it seemed to stimulate vibrations in the vocal folds,” says Ley.

He found applying the vibrator to the top of the head and cheeks helped to increase specific overtones as well. After these results, he decided to take his idea to a friend in speech pathology to explore its potential for helping to relieve more serious cases of vocal stress.

“This is the great thing I´ve found about the university. I´ve gone with what I´ve considered to be pretty wacky ideas to people in other departments and they say, ℠That sounds odd, but I´m willing to go with you on this’,” Ley said.

Sara Farb, a Toronto actress, was suffering from laryngitis in a production of Next to Normal, a high-octane, vocally demanding musical. She said after she tried the vibrator-to-throat application, “it was like my voice had been polished and was completely brand new.

“It was so absent of stress, even though the show was a stressful one to do,” Farb said in a statement. “I sent David a message that night saying he may have changed my life. I don´t mean to be dramatic, but it was drastic. I will never forget that performance.”

According to Ley, it is still too early to march out definitive scientific claims on the vibrator technique working, but he plans to present his method at the Voice Foundation Symposium in Philadelphia next June.

For those actors and actresses who do not want to be seen massaging their throats with a sex toy before a big performance, one San Francisco startup company is making a solution. CRAVE announced on Valentine’s Day this year it has officially launched a discreet sex toy. With an inconspicuous vibrator tucked away in a pocket or purse, and the confidence of a new study behind their backs, intrepid actors and actresses can now walk into their next performance and blow everyone away with their powerful vocal projections.

Scientists Find Specific Human Brain Cells That Make Mice Smarter

WATCH VIDEO: [Forebrain Engraftment In Mice]

redOrbit Staff & Wire Reports – Your Universe Online

A group of non-neural cells found in the human central nervous system may be more essential to the complexity of our brains than previously believed, according to new research published in Thursday´s edition of the journal Cell Stem Cell.

A team led by Steven A. Goldman and Maiken Nedergaard of the University of Rochester Medical Center´s (URMC) Center for Translational Neuromedicine transplanted a special type of glial cells known as astrocytes into mice. By doing so, they learned that the cells could influence communication within the rodent´s brain, allowing the creatures to learn at a faster pace than before.

Astrocytes, which are found in the brain and spinal cord, are responsible for a variety of tasks within the body, including providing nutrients to the nervous tissue and helping to repair nervous system organs following traumatic injuries. According to Goldman and Nedergaard, they are larger and more complex in humans than they are in other creatures, leading them to believe that they may be part of the reason that has given mankind higher-level cognitive functions than other species.

“This study indicates that glia are not only essential to neural transmission, but also suggest that the development of human cognition may reflect the evolution of human-specific glial form and function,” Goldman, co-senior author of the study, said in a statement. “We believe that this is the first demonstration that human glia have unique functional advantages. This finding also provides us with a fundamentally new model to investigate a range of diseases in which these cells may play a role.”

Previous research conducted at URMC has helped scientists learn the role that astrocytes and other glia cells play in brain function. Experts at the New York-based research hospital demonstrated that astrocytes communicate with neurons and with each other, rather than just supporting the neurons.

As Nedergaard explained, while the main role of these cells is to enhance neural transmission, she and her colleagues have also determined that as astrocytes evolve and become larger, more complex, and more diverse — as they have in humans — the complexity of brain function also increases.

Since there are a greater number of astrocytes in men and women than in other species, and they are larger and more diverse, the researchers believe that they could possibly coordinate far more synapses than in mice or similar animals. The URMC researchers’ observations led them to believe that these glial cells could help regulate humanity´s higher cognitive functions, and that if they are transplanted into mice, they could have a similar affect.

“In a fundamental sense are we different from lower species,” Goldman said. “Our advanced cognitive processing capabilities exist not only because of the size and complexity of our neural networks, but also because of the increase in functional capabilities and coordination afforded by human glia.”

“I have always found the concept that the human brain is more capable because we have more complex neural networks to be a little too simple, because if you put the entire neural network and all of its activity together all you just end up with a super computer [sic],” added Nedergaard. “But human cognition is far more than just processing data, it is also comprised of the coordination of emotion with memory that informs our higher abilities to abstract and learn.”

In order to determine whether or not human glial cells did enhance the brain´s capabilities, the URMC researchers isolated some of the cell progenitors that give rise to astrocytes and transplanted them into the brains of neonatal mice. As those rodents matured, the implanted glial cells overwhelmed the host´s native cells, but did so without damaging the creature´s pre-established neural network.

“The human glia cells essentially took over to the point where virtually all of the glial progenitor cells and a large proportion of the astrocytes in the mice were of human origin, and essentially developed and behaved as they would have in a person’s brain,” Goldman said.

Closer analysis revealed that the human glia had two major impacts on the brains of the mice.

First, they increased the speed and distance at which a signal travels to and amongst adjacent astrocytes within the brains — a phenomenon known as the calcium wave.

Second, the transplanted mice developed more rapid and sustained long-term potentiation (LTP), which affects how long neurons are affected by brief electrical stimulations. That indicates that the transplanted cells improved the rodents´ learning capabilities.

“The bottom line is that these mice demonstrated an increase in plasticity and learning within their existing neural networks, essentially changing their functional capabilities,” said Goldman. “This tells us that human glia have a species-specific role in intellectual capability and cognitive processing. While we’ve suspected for a while that this might be the case, this is really the first proof of this point.”

Breakthrough Study: Nanoparticles Laced With Bee Venom Selectively Destroy HIV Virus

Brett Smith for redOrbit.com – Your Universe Online

According to a new report in the journal Antiviral Therapy, researchers from the Washington University in St. Louis have found that nanoparticles loaded with bee venom are capable of destroying the human immunodeficiency virus (HIV) while leaving the body´s cells unharmed. In a radical departure from traditional attempts to treat HIV, the research team says that the nanoparticles could be used to develop a prophylactic gel capable of stopping the spread of AIDS.

“Our hope is that in places where HIV is running rampant, people could use this gel as a preventive measure to stop the initial infection,” said lead author Joshua L. Hood, MD, PhD, a researcher and instructor at WUSTL.

The key ingredient in bee venom is a toxin called melittin, which is able to break through the tough protective envelope that surrounds viruses like HIV. Besides being effective against viruses, other research has shown that melittin-loaded nanoparticles are also effective tumor-cell assassins.

In addition to killing viruses, the new study is promising because it shows that the nanoparticles do not harm normal cells. To accomplish this, the research team engineered protective ℠bumpers´ to the nanoparticles´ surface so that the particles harmlessly bounce off when they come into contact with much larger body cells.

However, since viruses are much smaller than the nanoparticle, the HIV viral bodies slip between the bumpers, allowing bee toxin to access the virus.

According to Hood, this new approach differs from the traditional way that most anti-HIV drugs work, which is by inhibiting the virus´s ability to reproduce. The conventional strategy is flawed because it does not put down the initial infection, and some strains have been found to reproduce anyway.

“We are attacking an inherent physical property of HIV,” Hood said. “Theoretically, there isn´t any way for the virus to adapt to that. The virus has to have a protective coat, a double-layered membrane that covers the virus.”

The new HIV treatment was made possible by the nanoparticle delivery mechanism, which was developed in previous experiments for other purposes.

“The basic particle that we are using in these experiments was developed many years ago as an artificial blood product,” Hood said. “It didn´t work very well for delivering oxygen, but it circulates safely in the body and gives us a nice platform that we can adapt to fight different kinds of infections.”

While it was not explicitly discussed in the journal report, Hood explained that a prophylactic gel containing the engineered particles could easily be adapted to be used as birth control as well. However, in some cases couples may only want protection from HIV.

“We also are looking at this for couples where only one of the partners has HIV, and they want to have a baby,” Hood said. “These particles by themselves are actually very safe for sperm, for the same reason they are safe for vaginal cells.”

Because the nanoparticles themselves are not HIV-specific, the team is hoping this treatment can be applied to other viruses as well. For example, hepatitis B and C have the same kind of defensive envelope and would be also potentially be susceptible to melittin-loaded nanoparticles.

French Women Trailing Behind Their European Neighbors When It Comes To Sport And Exercise

French women are less likely to spend any time on physical activities including sport, exercise or even household chores, compared to women in Germany, Denmark, Sweden and the UK, according to a new survey. The multi-national survey on sport and exercise habits also reveals that more than 50 per cent of French women did not play competitive sport or spend any time on intensive workouts such as running or cycling in a given week. As the French women’s football team prepare for this summer’s UEFA Women’s EURO in Sweden, the countdown to the championships offers an opportunity for women to kick start heart-healthy physical activities and set themselves the goal of being more active.

“Playing sport can be an important part of an active, healthy lifestyle. In combination with everyday physical activities, such as gardening or even doing household chores, sport can help reduce the risk of heart disease, the number one killer of women, responsible for the deaths of 1 in 3 women worldwide. According to the World Health Organization’s Global Recommendations on Physical activity for Health, adults aged between 18-64 years should do 150 minutes of moderate physical activity (gardening, dancing or brisk walking) or 75 minutes of vigorous physical activity (playing sport, running or aerobics) per week. Ahead of International Women’s Day, we encourage women to take care of their heart health to avoid paying the penalty of an inactive lifestyle”, said Johanna Ralston, CEO of the World Heart Federation.

The survey reveals that French women are not only indifferent to sport and exercise, but 42 per cent of women do not do enough physical activity per week, putting themselves at risk of cardiovascular disease (CVD), which includes heart disease and stroke. More than 2 million women in France are just below the threshold for a healthy level of physical activity. They could reduce their risk of CVD if they set themselves the goal of doing just one hour more per week of playing sport or doing everyday physical activities such as gardening or household chores.

The multi-national survey conducted by YouGov in France, Sweden, UK, Denmark and Sweden, and commissioned by the World Heart Federation reveals that in the France:

-42 per cent of women in France did not do the recommended amount of physical activity in the week of the survey, compared to 34 per cent in the UK, 33 per cent in Sweden, 19 per cent in Denmark and 19 per cent in Germany
-22 per cent of women admitted to being physically inactive and did not exert themselves at all
-French men were more likely to do the recommended amount of physical activity in the week of the survey, with 75 per cent of French men doing at least 150 minutes of physical activity, compared to just 58 per cent of French women

The World Heart Federation’s “Make a Healthy Heart your Goal” campaign in partnership with UEFA Women’s EURO 2013 will be officially launched tomorrow on International Women’s Day. The campaign encourages women and girls to set themselves the ‘goal’ of becoming more physically active, by practicing sports such as football and incorporating physical activities into their everyday lives, to reduce the risk of heart disease and stroke.

“Ahead of the UEFA Women’s EURO 2013 in July, we are calling on women and girls across Europe to achieve their physical activity ‘goal’ by playing football. Football is an empowering and unifying experience for women and girls. UEFA believes that every girl should have the opportunity to play football locally regardless of skill or talent and it is our goal to support this aim through our partnership with the World Heart Federation,” said Karen Espelund, Member of the UEFA Executive Committee and Chairwoman of the UEFA Women’s Football Committee.

On the Net:

Using Acid Reflux To Kill Cancer Cells

A University of Central Florida chemist has come up with a unique way to kill certain cancer cells — give them acid reflux.

Chemistry professor Kevin Belfield used a special salt to make cancer cells more acidic — similar to the way greasy foods cause acid reflux in some people. He used a light-activated, acid-generating molecule to make the cells more acidic when exposed to specific wavelengths of light, which in turn kills the bad cells. The surrounding healthy cells stay intact.

The technique is a simple way around a problem that has frustrated researchers for years. For photodynamic therapy (the special laser-light treatment) to work, cancer cells loaded with photosensitizers need oxygen to trigger the fatal reaction. But by their very nature, most cancer cells lack oxygen. Nonetheless, scientists were intent on making the photodynamic system work because it offers a way to target cancer cells deep within human tissue without causing a lot of collateral damage.

Instead of focusing on oxygen, Belfield flipped the problem around and found another way to poison the bad cells, while protecting the healthy ones.

“It’s the first time we’ve found a way around the oxygen problem,” Belfield said. “This work is truly ground breaking. It should eventually provide a therapeutic means to treat certain types of cancers with minimal side effects. It should also be a very useful tool for cell biologists and biomedical researchers. It could even find a place in treating other diseases such as neurodegenerative diseases.”

His work was recently published in the Journal of the American Chemical Society.

Belfield and his team at UCF used human colorectal carcinoma cells for the study, which was funded by the National Science Foundation and the National Institutes for Health. More research is needed to determine that there are no serious side affects in humans and whether the technique will work on a variety of cancers, but Belfield is optimistic.

“Predicting commercialization is difficult at best,” he said. “But we are well situated to forge ahead”.

So how did Belfield come up with such an “outside the box” approach? His other non-medical related research was the inspiration.

Belfield has developed a three-dimensional, optical data-storage system, which involves the use of acid generators. About six years ago he wondered if his approach could have applications in medical therapy.

“It took about five years to get someone in my research group interested to take on the unorthodox project,” Belfield said. “But it seems to have paid off.”

Other contributors to the research are Xiling Yue, Ciceron O. Yanez and Sheng Yao, researchers and students at UCF students focusing on chemistry or photonics.

Belfield is one of the pioneers in two-photon absorbing materials, two-photon photochemistry, and two-photon photophysics. His research spans a number of disciplines including organic, polymer, and physical chemistry, as well as optics, optical microscopy, and bioimaging. His research has potential applications in everything from the way people store data on DVDs to fighting cancer.

On the Net:

‘Prevent Death’ Message More Effective Than ‘Save Life’ In Blood Donation Campaigns

‘Prevent loss’ message better than ‘provide benefits’ to increase volunteerism

Subtle changes in messaging can have a profound impact on the effectiveness of charitable messages such as calls for blood donations, according to research published March 6 in the open access journal PLOS ONE by Eileen Chou from the University of Virginia and co-author Keith Murnighan at Northwestern University.

Though chronic shortages in U.S blood banks could be alleviated by a small increase in the number of blood donors, people are not always motivated enough to help. In the current study, researchers collaborated with the Red Cross to assess the effects of changing the urgency and messaging of a call for blood donations. The scientists found that on a college campus, describing blood donations as a way to “prevent a death” rather than “save a life” significantly increased the rate of donations.

In a second study, the researchers assessed the effects of these slight changes in framing a charitable message on people’s emotional motivation for a monetary donation. Here, they found that framing an appeal as “helping people to avoid a loss” rather than “helping people to gain benefits” led to increased intentions to volunteer and more helping behavior. Volunteers presented with such “prevention of loss” messages were also more likely to expect larger donations to their cause. “These findings demonstrated a simple, reliable, and effective method for charities to significantly increase important helping behaviors,” Chou said.

On the Net:

Shoes That Replicate Being Barefoot May Be Bad For Your Bones

WATCH VIDEO: [Caution on Barefoot Running Shoes]
Alan McStravick for redOrbit.com – Your Universe Online
If you´ve expressed any interest in exercise on Google or ℠liked´ a themed race on Facebook, you have, more likely than not, had targeted advertising pop-ups introducing you to the growing trend of minimalist and barefoot footwear. On running trails and at races, the prevalence of ℠barefoot running´ has likely not gone unnoticed.
In a new study by researchers from Brigham Young University (BYU), the benefits and pitfalls of this relatively new footwear are explored.
In the scope of human history, shoes designed specifically for running and exercise are a relatively new concept. In fact, shoes designed specifically for the runner didn´t truly exist in the US until the mid-1960s. A small company called Blue Ribbon Sports imported the new Tiger shoes from Japan. From this humble beginning, Blue Ribbon Sports was responsible for generating interest in the burgeoning running-shoe industry. In 1978, Blue Ribbon Sports changed their name to Nike and the rest is history.
Prior to this renaissance in athletic apparel, barefoot running was the only option for millennia. Despite the plethora of shoe options that are now available to the casual and serious runner, many athletes are opting for a more minimalist approach to their foot covering, bringing the concept of barefoot running back into vogue.
This backward-looking advancement in design is largely credited to a January 2010 article published in Nature. The article focused on a Harvard University study that detailed foot-strike patterns and the impact profiles of barefoot running as compared to running with shoes. Other large media outlets like The New York Times, Runner´s World and The Wall Street Journal picked up on this study and interest in barefoot running was instantly recognized.
It is important to note many people completely misinterpreted the initial study. The belief was fostered that barefoot runners suffered fewer injuries and were able to run faster than their shoe wearing counterparts. In fact, the study only claimed people “were able to land comfortably and safely when barefoot or in minimal footwear by landing with a flat foot (midfoot strike) or by landing on the ball of the foot before bringing down the heel (forefoot strike).”
Dr. Daniel Lieberman, one of the Harvard study leaders, claims mid and forefoot striking does not cause the sudden, large impacts that occur when you heel strike. As such, barefoot running allows the athlete to run on hard surfaces without suffering discomfort from the landing.
Runners who wear traditional running footwear tend to heel strike. This means the heel hits the ground first, causing the lower leg to come to a stop during the impact while the body continues to move across the knee. The initial impact of a heel strike is responsible for the heel having to absorb a full two to three times the body´s weight.
A midfoot strike allows a runner to land on the ball of his/her foot. This keeps the foot, at impact, in line with the hip. Often, a midfoot strike will keep the heel from even coming in contact with the ground. The larger foot surface area reduces overall force and allows the knees to act as shock absorbers.
A forefoot strike bears striking similarities to the midfoot strike. In this running pattern, the ball of the foot strikes the ground just below the fourth and fifth metatarsal. The body experiences less stoppage at impact and there is more shock absorption distributed among the knees, hips and back.
Going into more detail, Lieberman continues by saying that when running barefoot, the individual lands on the fourth and fifth metatarsal and then the heel goes down. This action, according to Lieberman, converts energy into what is known as rotational energy. Conversely, a heel strike causes the heel to come to a complete stop during the running motion. Despite their findings, the Harvard team points out that “no study has shown that heel striking contributes more to injury than forefoot striking.”
Further interest in minimalist running was sparked in the running community with the publishing of Christopher McDougall´s bestselling book ‘Born to Run: A Hidden Tribe, Superathletes and the Greatest Race the World Has Never Seen.’ In it, McDougall writes on the mechanics of running.
To support his claims, he focused on the Tarahumara Indians of Mexico. Members of this tribe are able to run 100 miles and more a day. The rugged Copper Canyon presents exceptionally challenging terrain. And they complete their daily runs wearing foot coverings made only of old tires and leather.
Anecdotal evidence, like that of the Tarahumura Indians, has also been coupled with the documented success of professional runners who have achieved stunning feats with nothing on their feet.
For instance, Abebe Bikila, running for Ethiopia in the 1960 Summer Olympics, took home the gold medal, winning the marathon in 2 hours, 15 minutes, 16 seconds. Though he had a shoe sponsor for the race, the shoes built for him ultimately didn´t fit and he chose to run without them, exactly as he had trained for the race back home in Ethiopia.
In the latest BYU study, conducted by a team of exercise science professors, they caution that runners wishing to make the transition from a traditional running shoe to the newly popular ℠barefoot´ five-finger running shoes should make certain the transition is completed slowly.
The study details how runners who expedite their transition in shoe style are at an increased risk of suffering injury to bones in the foot. These injuries could even lead to possible stress fractures. And with these new shoe varieties representing an estimated 15 percent of the $6.5 billion running shoe industry, the team believes the import of their study is evident.
“Transitioning to minimalist shoes is definitely stressful to the bones,” said Sarah Ridge, study lead author and assistant professor of exercise science at BYU. “You have to be careful in how you transition and most people don´t think about that; they just want to put the shoes on and go.”
For the study, the research team observed 36 experienced runners over a 10-week period. Their findings have been published online ahead of print in the journal Medicine & Science in Sports & Exercise.
Prior to running observation, each subject in the study underwent MRIs on their feet. At the start of the study, half of the participants were asked to gradually transition into five-finger minimalist shoes. The other half of the participants continued to run in a more traditional style of running shoe.
Runners who were switched to the minimalist shoe were advised to follow an industry-suggested protocol associated with this sort of footwear transition. In the first week, they were asked to only engage in a short one-to-two-mile run. Each week thereafter, they were advised to add another short run. After week three, subjects were asked to then add additional mileage to their runs as they felt comfortable.
At the culmination of the 10-week study period, each athlete again had their feet subjected to an MRI. The findings revealed those athletes who transitioned to the minimalist shoes experienced greater increases in bone marrow edema. This condition is indicative of inflammation that causes excessive fluid in the bone. Additionally, the minimalist footwear group also saw a higher incidence of stress injuries than those runners utilizing traditional running shoes.
“Whenever a bone is impacted by running (or some other repetitive action), it goes through a normal remodeling process to get stronger,” Ridge said. “Injury occurs when the impact is coming too quickly or too powerfully, and the bone doesn´t have a chance to properly remodel before impact reoccurs.”
Female runners in the footwear transition group, it was found, suffered more stress injuries to the foot than their male counterparts.
Much like Lieberman with the Harvard study, Ridge and her BYU cohorts offer a caveat to their study in the hopes it, too, will not be misinterpreted. They were careful to stress their findings do not necessarily mean a minimalist shoe is bad. They do, however, find contention with the industry-recommended protocol regarding transition to this shoe type. They claim, in order to minimize potential injury risk, the transition should occur over a period longer than 10 weeks and runs should be conducted at a lower intensity and mileage.
“People need to remember they´ve grown up their whole life wearing a certain type of running shoe and they need to give their muscles and bones time to make the change,” Johnson said. “If you want to wear minimalist shoes, make sure you transition slowly.”
Leading outdoor and athletic outfitter REI offers tips and guidelines on their website for anyone considering the move from a traditional shoe to the new minimalist footwear. One important point made regards runners who have low arches. As their site states, “Heavily pronating runners — those whose feet flatten during weight-bearing exercise — may struggle to adjust to the lack of arch support,” offered by these shoes.
Ridge and her co-authors on the study, BYU exercise science faculty Wayne Johnson, Ulrike Mitchell and Iain Hunter state this will be but the first of many studies to focus on the minimalist running shoe. The plan, over the next several months is to publish enough research that a clear set of recommendations will emerge for anyone who might be considering making the switch to this primal influenced footwear.

Processed Meats May Be Killing You Softly

Brett Smith for redOrbit.com – Your Universe Online

According to the aging crooner Morrissey, “meat is murder,” yet a new study in the journal BMC Medicine suggests the eating too much meat may also be suicide.

An international study involving almost half a million people and spanning an average of 13 years found a direct correlation between the consumption of processed meats and fatal health conditions such as cardiovascular disease and cancer.

“Risks of dying earlier from cancer and cardiovascular disease also increased with the amount of processed meat eaten,” said lead author Sabine Rohrmann of the University of Zurich. “Overall, we estimate that 3 percent of premature deaths each year could be prevented if people ate less than 20 grams processed meat per day.”

The study´s authors define processed meat as meat that has been treated in some way to extend its shelf life, change its taste, or make it more palatable.

Although people who ate higher amounts of processed meat were also more likely to engage in smoking, be overweight and have other associated risk factors — the researchers accounted for these additional risk factors and still found that processed meat had a negative impact on long-term health outcomes.

While one in every 17 people died over the course of the study, those eating more than 160 grams of processed meat per day — the equivalent of about two sausages and a slice of bacon — were 44 percent more likely to die earlier than those who ate only around 20 grams. Overall, the study encompassed roughly 10,000 cancer-related deaths and 5,500 deaths related to cardiovascular disease.

“We estimated that 3.3 percent of all deaths could be prevented if processed meat consumption were below” 20 grams per day, the authors wrote.

In the report, the team said their statistics on participants´ deaths were taken from death certificate records, noting that these records are known to over represent death due to heart attack.

The report also mentioned that the National Institutes of Health-American Association of Retired Persons (NIH-AARP) has found a direct connection between both red and processed meat and an increased mortality risk. In fact, that organization suggested a stronger risk correlation for red meat over processed meat.

Many health experts have spoken out on behalf of the BMC report and advocate for measure to be taken against the heavy consumption of processed meats.

“This research adds to the body of scientific evidence highlighting the health risks of eating processed meat,” Dr. Rachel Thompson, from the World Cancer Research Fund, told the BBC News. “Our research, published in 2007 and subsequently confirmed in 2011, shows strong evidence that eating processed meat, such as bacon, ham, hot dogs, salami and some sausages, increases the risk of getting bowel cancer.”

“This is why World Cancer Research Fund recommends people avoid processed meat,” Thompson added.

Tracy Parker, a spokesperson from the British Heart Foundation, also told the UK news agency that processed meat might be linked to an early death, but that other dietary choices may have also played a role.

“[The study subjects] were found to eat less fruit and vegetables and were more likely to smoke, which may have had an impact on results,” she said. “Red meat can still be enjoyed as part of a balanced diet.”