Is Childbirth Possible with Fibromyalgia?

child birth

Image:Ahuli Labutin/shutterstock

The decision to have a child is always a complicated one, with many factors to consider. This is made all the more complex when you have issues of chronic illness to keep in mind. You need to consider the impact of pregnancy on your body, the way your illness may affect childbirth, and how fibromyalgia will affect your ability to care for your babies. Pregnancy and childbirth are often possible with fibromyalgia, but your experience may differ from that of a woman in normal health. Here are some of the things to consider.

Pregnancy

Not many details are known about how fibromyalgia may affect fertility, but what limited information is known suggests that fertility is not significantly impacted beyond the manner in which fibromyalgia symptoms interfere with intercourse.

Once pregnant, however, some women with fibromyalgia experience more pain than those without fibromyalgia. Pregnancy is both physically and emotionally stressful for many women, and stress is a common trigger for fibromyalgia flares. Unfortunately, none of the medications that are currently prescribed for fibromyalgia (e.g. Lyrica; painkillers) are completely safe for use during pregnancy, and you will usually have to stop taking any such medicines during the pregnancy.

Childbirth

Most women with fibromyalgia are capable of experiencing a natural childbirth without complications. There is nothing unique to the illness of fibromyalgia that makes childbirth more risky or difficult. However, the rate of Cesarean sections is extremely high for all women, with approximately 1 in 3 women having a C-section, with or without fibromyalgia. Keep these statistics in mind when considering the recovery process from childbirth if you have fibromyalgia.

Breastfeeding

Breastfeeding is the healthiest feeding option for infants, and most hospitals and public health organizations strongly recommend it for at least the first six months and even longer. However, even though 81 percent of new mothers are breastfeeding at the time that they leave the hospital, only 29 percent are still nursing at six months. There are many factors that contribute to low breastfeeding rates at six months, including lack of workplace support.

However, one study suggests that women with fibromyalgia may find breastfeeding to be more painful, and after pregnancy without pain medication, mothers are faced with the additional decision whether to breastfeed and continue to forego the medication or to switch to formula feeding and be able to take the needed medicines. Some evidence also suggests that women with fibromyalgia may have difficulty producing an adequate milk supply to feed their babies.

Changes after Birth

Whether your fibromyalgia symptoms will be better or worse after pregnancy is variable and no woman can count on what her experience will be. Some women report that their fibromyalgia begins after childbirth when they did not have problems with it beforehand.

Women with fibromyalgia may also be more likely to experience postpartum depression, particularly because depression is already a common symptom of fibromyalgia. However, antidepressants may be an option for treating postpartum depression, even for women who are breastfeeding. Some antidepressants are safe for nursing mothers.

Researchers finally observe rare protostar gas disk

For the first time ever, Japanese researchers have been able to directly observe an astronomical process that has been elusive up until now—an early phase in stellar evolution that involves the formation of the gas disk that feeds nascent stars and births planets.

The observations were of a baby star (protostar) named TMC-1A, which is located 450 light years away from Earth, in the constellation Taurus. Like other stars, TMC-1A formed when an enormous gas cloud collapsed under the weight of its own gravity, and as it’s still forming, it’s still surrounded by the remains of that gas cloud.

Of course, baby stars draw on this sort of blanket of gas on to grow. However, the gas doesn’t flow directly into the protostar from outside; instead, it accumulates in a spiral, forming a hot, swirling disk around that star that then feeds into it.

But researchers are uncertain about when these gas disks form, and how they later evolve with the growing star, as previous technology (radio observations) has lacked the sensitivity and resolution to allow researchers to view this phenomenon.

“The disks around young stars are the places where planets will be formed,” said lead author Yusuke Aso, a graduate student at the University of Tokyo, in a Phys.org statement. “To understand the formation mechanism of a disk, we need to differentiate the disk from the outer envelope precisely and pinpoint the location of its boundary.”

Which is where the researchers stepped in. According to the paper in The Astrophysical Journal, they have successfully used the Atacama Large Millimeter/submillimeter Array (ALMA), an array of radio telescopes in Chile, to observe this boundary between the inner rotating disk (which “feeds” the star) and the outer infalling gas envelope (which provides the gaseous “nutrients” to the disk).

For TMC-1A in particular, this boundary happens to be located 90 astronomical units from the baby star’s center—three times longer than Neptune’s orbit of the Sun. The gas infall rate was measured to be a millionth of the mass of the Sun per year—at a speed of 1 kilometer per second (roughly 2,240 miles per hour).  And, while gravity is causing this gas to fall inward, the gas isn’t falling as quickly as it would in normal freefall, indicating something (perhaps a magnetic field around the star) is slowing the gas down.

Moreover, the disk itself was observed to obey Keplerian rotation—as in the materials which orbit closer to the baby star revolve faster than material farther out. And, after measuring TMC-1A’s speed of rotation, they were able to calculate its mass: Currently, it’s 0.68 times the mass of the Sun.

“We expect that as the baby star grows, the boundary between the disk and the infall region moves outward,” said Aso. “We are sure that future ALMA observations will reveal such evolution.”

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Image credit: ALMA

New study could lead to a revolutionary heart failure pill

The buildup of scar tissue that slowly leads to heart failure could be reduced and replaced by health heart muscle using a method developed by researchers at the University of North Carolina School of Medicine.

The treatment could come in the form of a pill, and could lead to significantly improved quality of life for heart patients.

“Our past work brought hope that we could one day improve heart function in people with heart failure by converting scar tissue into beating heart muscle,” said Li Qian, PhD, assistant professor of pathology and laboratory medicine and senior author of a new study.

“But that was more of a proof-of-principle study, and the conversion rate was quite low. Now we have found the barrier to conversion, and by removing it, we have been able to significantly increase the yield of muscle-like cells.”

The “past work” refers to a 2012 study in which Qian and her colleagues created a blend of proteins to converted fibroblasts, which create scar tissue, into cardiomyocytes – heart muscle cells that beat on their own just as regular heart muscle cells do.

The approach lowered the likelihood of uncontrolled cell growth and tumor formation, shrinking the size of scar tissue and improving heart function in experiments on mice.

Getting quicker results

However, the new study has dealt with how slowly improvements came with the 2012 method.

“We wanted to have a better yield and shorten the conversion time so in the future this process could be fast, easy, and efficient for disease modeling or for treatment,” Qian said.

Their chance came with they discovered that a gene called Bmi1 interfered with the expression of other key genes needed to convert fibroblasts into heart muscle cells.

When the team depleted Bmi1, the percentage of fibroblasts that transformed into heart muscle cells increased 10-fold. This development also allowed for a simpler cocktail of proteins.

Ultimately, that cocktail could be put into a pill that could be given to heart patients, reducing the long-term loss of functional heart tissue.

The next step is to test the method on larger animals, which if successful could lead to a pill within 10 years.

Heart failure affects an estimated 5.7 million people in the United States, but currently has no cure, and treatment involves piecemeal methods that are cobbled together.

Symptoms including shortness of breath, fatigue, and swelling all worsen over time as a heart weakens.

“Our hope is that this approach could extend the lives of people with heart failure and markedly improve their quality of life in the future,” said Qian, who is also a member of the McAllister Heart Institute at UNC.

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Image credit: Thinkstock

Climate-related food losses could cause 500K extra deaths in 2050

A new study which is being hailed as “the strongest evidence yet that climate change could have damaging consequences for food production and health worldwide”  suggests that up to 500,000 adults could die in 2050 due to temperature-related changes to diet and bodyweight.

The half-million deaths would be due to reduced crop productivity, Dr. Marc Springmann of the Oxford Martin Program on the Future of Food at Oxford University in the UK and his colleagues reported in latest edition of the journal The Lancet. In a modeling study, the team estimated how many fatalities could be linked to climate-related agricultural changes in 155 countries.

Topping the list was China, with 230.64 estimated deaths per million people in 2050, followed by Vietnam (125.53 deaths per million people), Greece (123.66) and South Korea (118.53). The other regions with more than 100 estimated deaths per million people were Madagascar (105.23) and India (104.95). Italy, Romania, Albania and Myanmar rounded out the top 10, while the US was 66th on the list with an estimated 27.72 deaths per million people in 2050.

“Much research has looked at food security, but little has focused on the wider health effects of agricultural production,” Dr. Springmann said in a statement. “Changes in food availability and intake also affect dietary and weight-related risk factors such as low fruit and vegetable intake, high red meat consumption, and high bodyweight.”

Stricter regulations could reduce climate-related deaths by 71 percent

If climate change causes fruit and vegetable consumption to decrease and forces people to eat more red meat, it would likely increase the incidence of heart disease, stroke, and cancer, as well as the frequency of death due to those non-communicable diseases, the study authors said.

“Our results show that even modest reductions in the availability of food per person could lead to changes in the energy content and composition of diets, and these changes will have major consequences for health,” Dr. Springmann added. In fact, the research found that, left unchecked, climate changes caused by greenhouse gas emissions could lead to a one-third reduction in food availability within the next four decades.

Such drastic losses could lead to a 3.2 percent average reduction in food available to each person, equal to nearly 100 less kilocalories per day, as well as a 4.0 percent reduction in vegetable and fruit intake (14.9 grams per day) and a 0.7 percent reduction in red meat consumption (0.5 grams per day). Based on those numbers, the researchers predict that such changes could be responsible for approximately 529,000 extra deaths in 2050.

While climate change would also lead to a reduction in obesity, reducing the number of deaths due to the condition by about 260,000 worldwide in 2050, those benefits are offset by an equal number of deaths linked to being underweight or malnourished, the authors wrote. By cutting emissions, however, the number of climate related deaths could be reduced by at least 29 percent by possibly as much as 71 percent, based on the strength of new regulations.

“Climate change is likely to have a substantial negative impact on future mortality, even under optimistic scenarios. Adaptation efforts need to be scaled up rapidly,” said Dr. Springmann. “Public-health programs aimed at preventing and treating diet and weight-related risk factors, such as increasing fruit and vegetable intake, must be strengthened as a matter of priority to help mitigate climate-related health effects.”

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Image credit: Thinkstock

Paleolithic bone tools are the oldest ever found in China

An analysis of 17 bone tools recovered from the Ma’anshan Cave site in southern China has revealed that they are the oldest formal artifacts of their kind ever discovered in the country, according to a new study appearing in the Journal of Archaeological Science.

Credit: ZHANG Shuangquan

Credit: ZHANG Shuangquan


Furthermore, barbed points discovered on the Paleolithic-era tools are among the earliest yet discovered outside of Africa, a team led by Gao Xing from the Chinese Academy of Sciences’ Institute of Vertebrate Paleontology and Paleoanthropology and Francesco d’Errico from the Université de Bordeaux in France reported in their recently-published paper.
According to Archaeology, the oldest of the artifacts were three awls discovered in the cave’s Stratum 6 that date back approximately 35,000 years ago. In addition, the researchers found a cutting tool, six spear points and awls in Stratum 5 that are an estimated 34,000 years old, and the barbed points were found in Stratum 3 and are at least 18,000 years old.
Credit: ZHANG Shuangquan

Credit: ZHANG Shuangquan


Each of the tools were originally crafted through grinding and scraping, while those found in Stratum 3 and Stratum 5 had also been polished, Xing, d’Errico and their colleagues explained. Changes in the tools between stratum indicate a possible shift in prey preference from medium sized mammals and fish to smaller ones, the study authors wrote.
Could shed new light on origins of bone tool technology
Bone tools, which according to Phys.org are formally defined as any artifact that has been cut, carved or otherwise modified to produce fully-shaped points, spears or awls, typically appear in the later parts of human history. Examples of such bone technology have been found in African sites, and early examples of such artifacts in other parts of the world have been rare.
stone scrape

Each of the tools was shaped using stones. (Credit: ZHANG Shuangquan)


Dr. Zhang Shuangquan said that the discovery of bone tools in Ma’anshan Cave “provides new materials for studies about the origin of bone tool technology in Africa and Eurasia,” while Xing added that the  research “demonstrates that bone tool technology shows rates of cultural turnover comparable to those observed in the Upper Paleolithic of Europe.”
According to the Daily Mail, anthropologists typically view the shift to producing bone tools as one of the signs indicating a major shift in human cognitive ability. This increasing brain power, they added, may have helped our ancestors, early Homo sapiens, to out-compete our early rivals such as the Neanderthals and the Denisovans to emerge as the dominant humanoid species.
While Homo sapiens are believed to have first evolved in Africa roughly 200,000 years ago, then spreading out from the continent some 60,000 years ago, recent archaeological studies uncovered  47 Homo sapiens teeth in China that date back to between 80,000 and 120,000 years ago, the UK newspaper added.
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Image Credit: ZHANG Shuangquan

Massive volcanic activity caused a polar shift on Mars, study claims

Massive amounts of lava spewed from a volcanic region roughly half the size of France about 3.5 billion years ago caused the outer layers of Mars to become displaced, and the Red Planet’s original north and south poles to change position, according to a new study.

As Sylvain Bouley, a geoscientist at the University of Paris-Sud, and his colleagues, reported Wednesday in the journal Nature, the discovery explains why dry river beds and underground regions of water ice are found in unexpected places, and could solve other Martian mysteries.

Credit: Sylvain Bouley et. al.

Credit: Sylvain Bouley et. al.

“If a similar shift happened on Earth, Paris would be in the Polar Circle,” Bouley told the AFP news agency, adding that the period of volcanic activity likely lasted for a few hundred million years and would have tilted the surface of the planet by 20 to 25 degrees.

The lava flow would have also created the Tharsis dome, a 2,000 square mile (5,000 square kilometer) wide, 7.5 mile (12 kilometer) thick plateau. The formation of this “aberration” would have caused the crust and layer of Mars to shift drastically , the study author noted.

Findings may explain positioning of riverbeds, underground ice

Bouley’s team compared their findings with a 2010 theoretical study that showed if the massive Tharsis dome was to be removed from Mars, it would cause the planet to shift on its axis, as well as other computer models and observations. Their analysis lead to a lightbulb moment.

“Scientists couldn’t figure out why the rivers,” which today are dry riverbeds today, “were where they are. The positioning seemed arbitrary,” he said to the AFP. “But if you take into account the shift in the surface, they all line up on the same tropical band.”

Similarly, the location of the Red Planet’s extensive frozen underground water ice has long been a source of confusion for scientists, who realized that they should be closer to the poles. Because of the new study, they now know that, at one time, they were. Furthermore, the findings also help explain why Tharsis dome is located on the “new” equator – it was necessary for planet to regain its equilibrium following the shift, Bouley told the news organization.

The study also challenges the notion that the rivers formed after the Tharsis dome, as the authors concluded that most of these waterways would have flowed from south to north whether the lava fields were there or not. However, Bouley cautioned that there were still questions that needed to be answered, such as whether or not the tilt caused Mars’ magnetic fields to stop working, and if it played any role in the planet losing its atmosphere.

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Image credit: NASA / JPL-Caltech / Arizona State University

Scientists develop carbon-negative electric car battery production technique

A team of scientists from Vanderbilt University and George Washington University may have just figured out a way to bite out of the global carbon crisis, but it’s not the way you might think—because it involves driving cars.

Well, sort of, as the team has managed to create electric car batteries that are carbon negative—meaning, their manufacturing process uses up atmospheric carbon.

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Running a carbon-negative world

As described in ACS Central Science, the team adapted a process that made its debut in August in Nano Letters. Known as a solar thermal electrochemical process (STEP), it effectively splits carbon dioxide, producing carbon and oxygen gas. The carbon is then turned into nanotubes, which are not only conductive, but stable, flexible, and stronger than steel.

“This approach not only produces better batteries but it also establishes a value for carbon dioxide recovered from the atmosphere that is associated with the end-user battery cost unlike most efforts to reuse CO2 that are aimed at low-valued fuels, like methanol, that cannot justify the cost required to produce them,” said Assistant Professor of Mechanical Engineering Cary Pint, of Vanderbilt University, in a statement.

Even better, though, the STEP process to make the batteries is solar-powered: Sunshine provides both the heat and electricity necessary to break down the CO2.

Credit: Julie Turner / Vanderbilt University

Credit: Julie Turner / Vanderbilt University

“Our climate-change solution is twofold: (1) to transform the greenhouse gas carbon dioxide into valuable products and (2) to provide greenhouse gas emission-free alternatives to today’s industrial and transportation fossil fuel processes,” said Professor of Chemistry Stuart Licht, of George Washington University.

The benefits of carbon nanotubes

“In addition to better batteries other applications for the carbon nanotubes include carbon composites for strong, lightweight construction materials, sports equipment and car, truck and airplane bodies.”

In particular, these nanotubes can be used in both lithium-ion batteries (commonly found in electric vehicles and iPhones) and sodium-ion batteries, which are currently sold as backup power supplies for electricity grids. The nanotubes replace the carbon anode used in commercial lithium-ion batteries; for sodium-ion batteries, nanotubes replace graphite electrodes.

For the lithium-ion batteries, the carbon nanotubes provide a small boost to performance—which increases when the batteries are charged quickly. When they added small defects in the carbon of sodium-ion batteries, meanwhile, the researchers discovered that the nanotubes lead to a more than 3.5 times better battery storage performance over the traditional sodium-ion option.

But perhaps most importantly, both kinds of carbon-nanotube batteries held up over the course of 2.5 months of continuous charging and discharging, showing no signs of fatigue.

Currently, Pint estimates that recycled carbon dioxide could compose around 40 percent of a battery, not including the packaging—which could likely be made out of a similar STEP process in the future, using up more carbon dioxide in the process.

“Imagine a world where every new electric vehicle or grid-scale battery installation would not only enable us to overcome the environmental sins of our past, but also provide a step toward a sustainable future for our children,” said Pint. “Our efforts have shown a path to achieve such a future.”

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Image credit: Vanderbilt University/Cary Pint

Tiny handprints in Libyan cave likely belong to lizards, not humans

Ancient sketches of handprints left behind at the Wadi Sura II natural rock shelter in the Libyan desert did not belong to human infants, other small primates, or even aliens, according to a newly published study by a team of French and UK archaeologists and paleoanthropologists.

As Emmanuelle Honoré of the McDonald Institute for Archaeological Research and the French National Centre for Scientific Research and her colleagues reported in the April 2016 edition of the Journal of Archaeological Science: Reports, a morphometric analysis of the size, proportions and morphology of the prints suggest they were made from the forefeet of reptiles.

Discovered in 2002, Wadi Sura II was found to contain thousands of sketches and prints, but it was the tiny, child-like “handprints” found in the prehistoric site which most fascinated experts, according to Archaeology and news.com.au. At least 13 prints believed to have been left behind between 6,000 and 8,000 years ago were found at the location, which is also known as the Cave of the Beasts, and until now it was believed that they were created by human babies.

In the new study, however, Honoré, Professor Brigitte Senut from the French National Museum of Natural History in Paris, and a team of primatologists, paleoanthropologists and other experts analyzed the proportions of the prints and found that they more closely matched the proportions of the forelimbs of a monitor lizard or very small crocodile.

Results not ‘definitive,’ but authors call them ‘very convincing’

As Honoré explained to news.com.au, she first saw the tiny “handprints” during a 2006 visit to the Wadi Sura II site, and noticed that they appeared to be smaller in size and with longer fingers than babies typically have. At that point, she started to wonder if they were actually human, or if they had a different origin than most researchers had come to believe.

Upon returning to the site a few years later, she decided to test her hypothesis. To start with, she measured the hands of her children and other babies in her family, and discovered that they were far smaller than those of her relatives. She then recruited a team of experts for further analysis on the markings, and found that they were not a 100 percent match for non-human primates either.

“After many discussions with my colleagues… we decided to investigate the reptile hypothesis,” Honoré told news.com.au. She then consulted with zoo officials and reptile experts, which led to the conclusion that they were likely made by lizards. While she said that their findings were not “definitive,” she added that the early results of their research were “very convincing.”

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Image credit: Emmanuelle Honoré

Want to lose weight? Just drink more water, says new study

Health experts have long touted the benefits of drinking water, and now new research from the University of Illinois  discovered evidence supporting that notion, finding that upping H2O intake can help people eat less and cut back on sugar, sodium, and saturated fat.

Writing in the latest edition of the Journal of Human Nutrition and Dietetics, kinesiology and community health professor Ruopeng An and his colleagues analyzed the dietary habits of more than 18,000 American adults, and found that those who drank one percent more water from any source (tap, bottled, cooler, or drinking fountain) reduced their total calorie intake by an average of 8.53 percent.

Those who increased their consumption by one to three cups per day lowered their total energy intake by 68 to 205 calories, as well as their daily sodium intake by 78 to 235 grams, the authors wrote. In addition, those individual decreased their sugar consumption by five to 18 grams and cholesterol consumption by seven to 21 grams per day.

In a statement, An said that the results were “similar across race/ethnicity, education, income levels, and body weight status,” and that the findings suggest ‘”It might be sufficient to design and deliver universal nutrition interventions and education campaigns that promote plain water consumption in replacement of beverages with calories in diverse population subgroups without profound concerns about message and strategy customization.”

Increased water consumption reduced calorie intake by 8.6

As part of their research, the authors examined data from four different waves of the National Center for Health Statistics National Health and Nutrition Examination Survey between 2005 through 2012. As part of the survey, participants were asked to catalog everything they ate or drank over the course of two days that were between three and 10 days apart.

An calculated the amount of plain water (not counting beverages such as unsweetened coffee, black tea or herbal tea) each person consumed, and found they drank an average of 4.2 cups of plain water per day and consumed an average of 2,157 calories per day. Approximately 125 of those calories came from sugar-sweetened beverages, while 432 came from junk food.

The researchers found that a one-percent increase in daily plain water consumption was linked to an average decrease in daily calorie consumption of 8.6, as well as slight reductions in the intake of sugary drinks and dessert foods, and reduced fat, sugar, sodium and cholesterol as well. These decreases were found to be greater in men than women, and in young and middle-age adults.

“Promoting plain water intake could be a useful public health strategy for reducing energy and targeted nutrient consumption in US adults,” the authors wrote, noting that the outcome  of their research “warrants confirmation in future controlled interventions.”

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Image credit: Thinkstock

 

440 million year old fungus fossil is the oldest known fossil of any land organism

A newly-discovered, 440-million-year-old fossilized fungus is not only the earliest example of its kingdom ever discovered, but is the oldest fossil of any land-dwelling organism unearthed to date, claims a new study published today in the Botanical Journal of the Linnean Society.

The fossil, which has been identified as Tortotubus, is structurally similar to many modern kinds of fungi and likely could store and transport nutrients through the process of decomposition, lead author Dr. Martin Smith of Durham University and his colleagues explained in a statement.

Three filaments of Tortotubus from Gotland, Sweden, showing growth of secondary branches along main filament. Credit: Martin R. Smith

Three filaments of Tortotubus from Gotland, Sweden, showing growth of secondary branches along main filament. Credit: Martin R. Smith

While the fossilized fungus has not yet been confirmed to have been the first organism found to have lived on land, it is the oldest preserved remains of a terrestrial organism discovered to date, and the authors believe that it played a key role in establishing the foundation for more complex plants, and eventually animals, to exist by starting the process of rot and soil formation.

“During the period when this organism existed, life was almost entirely restricted to the oceans,” said Dr. Smith, who performed his work while at Cambridge University. “Nothing more complex than simple mossy and lichen-like plants had yet evolved on the land. But before there could be flowering plants or trees… the processes of rot and soil formation needed to be established.”

Credit: Martin R. Smith

Credit: Martin R. Smith

Filling an important gap in the evolution of terrestrial life

While working with several microfossils discovered in Sweden and Scotland, Dr. Smith and his colleagues set out to reconstruct growth methods for two different kind of fossils that were first identified about three decades ago. In doing so, they discovered that what they thought were two different organisms actually represented two growth stages of the same lifeform.

By reconstructing this organism’s growth process, they demonstrated that the fossils represented mycelium, or the root-like filaments used by fungi to extract nutrients from soil. While it is hard to pinpoint exactly when plant life made the transition from water to land, fungi would have been an essential part in this move, as the rotting process it kick-started was vital for fertile soil.

Credit: Martin R. Smith

Credit: Martin R. Smith

In turn, the fertile soil would have allowed plants with root systems to establish themselves, and ultimately to help support animal life once it developed. Furthermore, the researchers noted that fungi are a key part of the nitrogen cycle, through which nitrates in the soil are gathered by roots and ultimately passed on to animals, by decomposing and converting nitrogen-rich compounds in plant and animal waste and remains back into nitrates so plants can collect them again.

According to Dr. Smith, Tortotubus was found to have a cord-like structure similar to that found in many modern fungi. In this structure, the main filament sends out both primary and secondary branches that stick back onto the main filament and ultimately envelop it. In today’s fungi, these structures are linked to the decomposition of matter, enabling fungal colonies to transport around nutrients and distribute them where they are most needed.

“What we see in this fossil is complex fungal ‘behavior’ in some of the earliest terrestrial ecosystems – contributing to soil formation and kick-starting the process of rotting on land,” he said. “This fossil provides a hint that mushroom-forming fungi may have colonized the land before the first animals left the oceans. It fills an important gap in the evolution of life on land.”

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Image credit: Martin R. Smith/University of Cambridge

Grey hair gene discovered, could lead to new treatments

It’s a moment many people dread: Finding their first grey hair. Regardless of gender, many people try to hide this sign of aging, leading women to spend an average of £10,000 ($14,000 USD) on dye in their lifetime, according to a 2013 survey by nice’n easy. But there may soon be a solution more permanent than dye, as researchers have discovered the first known gene for grey hair.
According to the paper published in Nature Communications, an international team of researchers drew blood from and examined the hair and scalp features of 6,630 genetically diverse volunteers across five Latin American countries (Brazil, Chile, Colombia, Mexico, and Peru).
The gene in question
After the volunteers’ blood was genotyped and the DNA sequences were compared, the team discovered that a gene variant known as IRF4, which is located on chromosome six, was tied to hair greying. IRF4 has been associated with skin, hair, and eye pigmentation in the past, but this find is a first.
“We already know several genes involved in balding and hair colour but this is the first time a gene for greying has been identified in humans, as well as other genes influencing hair shape and density,” lead author Dr. Kaustubh Adhikari, from University College London, told BBC. “It was only possible because we analysed a diverse melting pot of people, which hasn’t been done before on this scale.”
As to how exactly IRF4 causes greying, scientists aren’t sure. Hair itself is colored by melanocytes—cells that sit on the roots of hair and produce various pigments, which are then transferred into the hair fibers. Over time, these melanocytes cease to produce the hair color pigments, leading to grey hair. What triggers this change is still uncertain.
The same study also found nine other new associations between genes and hair and scalp features, including ones for hair and beard shape, balding, monobrows, and eyebrow and beard thickness. However, these genes aren’t likely the only cause for these features.
“The genes we have identified are unlikely to work in isolation to cause greying or straight hair, or thick eyebrows, but have a role to play along with many other factors yet to be identified,” said Adhikari.
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Image credit: Thinkstock

Do we have free will?

If one of your co-workers is swamped with work and you have some free time, you’re likely to give them a hand right?

Now, what if your supervisor orders you to assist someone – would you be more likely to avoid helping?

According to a new study in the journal Cognition, you probably would.

Led by a team of scientists from the University of California Santa Barbara, the study found that people tend to be naturally helpful, but it challenges the idea of free will by saying having a choice in the matter corrupts our natural helpfulness and results in impulsive selfishness. However, when given time to think about a situation, volunteers are able to bypass the observed tendency toward self-interest.

“Challenging a person’s belief in free will corrupts the more automatic and intuitive mental processes,” study author John Protzko, a postdoctoral psychology scholar at UCSB, said in a press release. “Our study suggests that a challenge to an individual’s belief in free will can shift this default mechanism — at least temporarily — to become intuitively uncooperative and cause an individual to act in their own self-interest.”

How did they study this?

In the study, researchers recruited more than 140 people to participate in an economic contribution game known as Public Goods. In the game, participants decided how much of their own “money” to put into a common pot. Their contributions were doubled and the communal pot was evenly split among the players. Players also kept the money they didn’t add to the pool.

At one point, researchers placed time limitations around volunteer contributions to the public pot, to impact the players’ feeling of free will. Some volunteers were informed they must read instructions and choose how much to give within 10 seconds; others were informed to wait 10 seconds before deciding.

At another point in the study, volunteers were told to read a passage that said neuroscience had just shown our decisions are created by intricate brain interactions before we have conscious access to them. A control group of volunteers read an article on nuclear energy.

The participants were then given a questionnaire on whether or not they felt like they had free will. Those who read the neuroscience passage agreed considerably less that they had free will than those who read the article on nuclear power.

“Challenging a person’s belief in free will did not seem to provide them with a conscious justification for uncooperative behavior,” Protzko said. “If it did, we should have observed fewer contributions when people were given adequate time to think about their decision on the amount to contribute.

“It’s very damaging to hear that we don’t have free will,” said Protzko. “Discounting free will changes the way we see things. Yet given time, we recover and go about our lives as though nothing were different.”

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Image credit: Thinkstock

Does marijuana stunt emotional growth?

A new study has found chronic cannabis users sometimes have trouble identifying, analyzing, and empathizing with emotions like joy, despair, and anger.

Published in the journal PLOS ONE, the study also found their observed effect could be counteracted based on if the emotions are clearly or implicitly seen.

Continuing the controversy

The use of cannabis is a controversial topic and so study author Lucy Troup, assistant professor of psychology at Colorado State University, said her team tried to approach cannabis use from an unbiased position.

“We’re not taking a pro or anti stance; but we just want to know, what does it do? It’s really about making sense of it,” Troup said in a press release.

In the study, researchers used an electroencephalogram (EEG) to evaluate the brain activities of approximately 70 participants. They all self-identified as long-term, moderate, or non-users of marijuana. The recruits were all checked out as legal users of cannabis under Colorado Amendment 64; meaning they were either medical marijuana users over 18 or recreational users 21 or older.

After being linked to an EEG, volunteers were asked to look at faces showing four different expressions: neutral, happy, fearful, and angry. Marijuana users exhibited a greater response to faces showing a negative expression, especially anger, than control subjects. On the other hand, marijuana users exhibited a smaller reaction to positive expression than the control subjects.

In another part of the experiment, the volunteers were asked to observe the emotion, and then explicitly identify the emotion. In those instances, users and non-users of marijuana were virtually the same.

However, when volunteers were asked to concentrate on the sex of the face, and later describe the emotion, marijuana users scored much lower than non-users. The researchers said this signified a depressed capacity to “implicitly” recognize emotions. Marijuana users were also less able to sympathize with the emotions.

The study appeared to indicate the brain’s capacity to assess emotion is affected by marijuana, but there may be some compensation that reverses that effect. There’s no distinction between users and non-users when they’re directed at a particular emotion, the study found. But on a deeper degree of emotion assessment, shown by the capacity to empathize, the response is decreased in marijuana users.

“We tried to see if our simple emotion-processing paradigm could be applied to people who use cannabis, because we wanted to see if there was a difference,” Troup said. “That’s how it all started.”

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Image credit: Thinkstock

NASA awards grant for development of quieter supersonic jet

Not content to simply reach for the stars, NASA announced on Monday that it was backing the development of a new fleet of supersonic passenger planes that it claims will be less dangerous, more environmentally friendly, and less expensive than previous versions of such jets.

During an event at Ronald Reagan Washington National Airport in Arlington, Virginia, NASA Administrator Charles Bolden announced that the US space agency had awarded a contract to a Lockheed Martin-led team developing a fleet of “low-boom” demonstration aircraft as part of a new aviation initiative introduced in NASA’s Fiscal 2017 budget.

“NASA is working hard to make flight greener, safer, and quieter – all while developing aircraft that travel faster, and building an aviation system that operates more efficiently,” Bolden said at the event, noting that work on a preliminary design for Quiet Supersonic Technology (QueSST) would commence at NASA’s Langley Research Center in Hampton, Virginia.

“It’s been almost 70 years since Chuck Yeager broke the sound barrier in the Bell X-1 as part of our predecessor agency’s high speed research,” he added. “Now we’re continuing that supersonic X-plane legacy with this preliminary design award for a quieter supersonic jet with an aim toward passenger flight.”

QueSST design seeks to eliminate the sonic boom

Work on the QueSST, which will be conducted under a task order against the Basic and Applied Aerospace Research and Technology contract at Langley, follows feasibility studies and research into what people all over the country deemed to be “acceptable” sound levels, NASA said.

Members of the agency’s Commercial Supersonic Technology Project then called on companies to submit design concepts for piloted test aircraft that could reach Mach 1 while emitting what is known as a supersonic “heartbeat” – soft thump instead of the loud boom typically linked to this type of aircraft. Lockheed Martin’s design was selected, and the company will receive nearly $20 million over the next 17 months to work on their preliminary QueSST designs.

The company’s team will also include subcontractors from GE Aviation of Cincinnati, Ohio, and Tri Models Inc. of Huntington Beach, California. Together, the three firms will work together to develop baseline aircraft requirements and a preliminary aircraft design with specifications. They will also be asked to provide documentation supporting their concept formulation and planning, which would be used to prepare for the designing, building and testing of the actual jet.

Once build, the prototype will then have to complete analytical and wind tunnel validation, said NASA. Future phases of the project will also call for public evaluation of the quieter supersonic jet design, they added. The work is part of the agency’s 10-year New Aviation Horizons project to reduce fuel consumption, noise and emissions through improved aircraft design.

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Image credit: Lockheed Martin

If aliens tried to contact us, could we even hear them?

As anyone who has ever tried to use a cell phone in a the middle of a wooded rural town knows, it can be difficult to hear someone trying to communicate with you if the signal is too weak, and that is the sort of problem that researchers are now trying to overcome on a cosmic scale.

In research published in the latest edition of the journal Astrobiology, scientists René Heller and Ralph Pudritz from McMaster University in Hamilton, Ontario, Canada are currently developing a way to ensure that we could detect weak signals that might be sent by extraterrestrial life forms that could be attempting to contact us from the far corners of the galaxy, or beyond.

While much of the effort centered around finding life on other worlds involve our efforts to reach out to those aliens, the study authors suggest that the best chance to make first contact could be to develop better ways of searching for those otherworldly signals instead of waiting and hoping that extraterrestrial civilizations someday hear us and respond.

As Heller and Pudritz explained in a statement, space researchers here on Earth spend most of their time trying to find planets and moons that are too far away to observe directly. Typically, these planets are studied by tracking their shadows and measuring the dimming of light as they transit or pass in front of their host stars during orbit.

Authors call for more intense monitoring of Earth’s transit zone

These observations can provide researchers with a vast array of information about other worlds, even those that cannot be seen directly. For instance, with measurements collected in this way, a team of scientists can estimate the average luminosity of the star, the temperatures on the surface of the planets, and whether or not they could maintain persistent surface water.

Using such techniques, scientists have identified dozens of potentially habitable planets, Heller and Pudritz said. But what if the same is true, and researchers on another world have detected the Earth using similar means, and have attempted to contact us? If their methods are similar to ours, they explained, we should begin intensely monitoring the region of space from which the Earth’s passage in front of the sun (also known as the “transit zone”) can be detected.

“It’s impossible to predict whether extraterrestrials use the same observational techniques as we do,” said Heller, an astrophysicist at the university’s Origins Institute. “But they will have to deal with the same physical principles as we do, and Earth’s solar transits are an obvious method to detect us.”

The transit zone is home to approximately 100,000 host stars which could potentially be orbited by habitable planets and moons, and there may be more that we have yet to detected, he and his colleague wrote. “If any of these planets host intelligent observers,” they added, “they could have identified Earth as a habitable, even as a living world long ago and we could be receiving their broadcasts today.”

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Image credit: Thinkstock

Fireball spotted, sonic boom heard in skies above Scotland

A bright flash over the skies of northeastern Scotland, and the rumbling sound that followed, were most likely caused by a meteor approximately 10 centimeters (4 inches) across which caused a sonic boom as it flashed across the sky, a UK astronomer has told BBC News. (Check out the BBC to see viewer-submitted videos of the flash)

The incident, which was observed as far south as Berwickshire in the Scottish Borders and was also visible in Perthshire, Aberdeenshire and the Highlands, took place sometime around 18:45 local time on Monday night. Several eyewitnesses called police after seeing the fireball. Others reported hearing a rumbling sound that lasted roughly 10 seconds, the Telegraph added.

While the cause of the bright flash and the rumbling sound have yet to be fully verified, Keith Horne, a professor at St. Andrews University, told the BBC that they were likely caused by an object traveling at speeds of nearly 30 kilometers per second, and meteorologists confirmed it could not have been a weather-related incident, as no thunderstorm activity was detected.

Robert Massey, deputy executive director for the Royal Astronomical Society, told CNN.com that, based on footage recorded by observers, the object could have been a low-altitude meteor igniting as a fireball. He called reports of the sound that accompanied it were “interesting” and added that anyone who caught a glimpse of the object “can consider themselves lucky.”

‘The most surreal thing I have ever experienced’

Horne told BBC Radio Scotland that the object was indeed a space rock that began to burn up once it hit Earth’s atmosphere. As it does so, it releases energy into the air, which results in “a bright flash.” While larger than the average dust-sized meteor, this object likely burnt up at an altitude of 32 kilometers (20 miles) without any bits reaching the surface, he added.

While the object most likely posed no danger and caused no damage, it did result in an unique show for those who, as Massey said, were lucky enough to have witnesses it. One driver named Jenni Morrison, who captured dashcam footage of the event, told the BBC that it was “the most surreal thing I have ever experienced.”

“It was pitch black and then all of a sudden it was like a light switch went on. It became daylight – the whole sky lit up. I looked at my son, he looked at me and then it just went black again,” she added. “We didn’t realize what it was at the time until we looked back on my dashcam. We saw the ball of light over the trees on the left side coming down at some speed and then a massive flash… It was scary and amazing at the same time.”

Monday’s event follows a much larger fireball event burned up, virtually unnoticed at the time despite releasing as much energy as 13,000 tons of TNT, according to the Telegraph. According to experts, an estimated 30 small asteroid enter and disintegrate in the planet’s atmosphere each year, with the majority of them falling over the ocean and having no impact on populated parts of the world.

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Image credit: BBC/Dee Scholes

520-million year old fossilized nervous system is the most detailed example ever found

Researchers from the University of Cambridge recently uncovered a 520 million year old fossil with a special designation– it’s the most detailed Cambrian period nervous system ever found.

The fossil is that of an ancient crustacean-like animal named Chengjiangocaris kunmingensis, which was recovered from southern China. C. kunmingensis, which belonged to a group of animals called fuxianhuiids, was an early ancestor of modern arthropods. It had a broad, nearly heart-shaped head shield, a long body, and pairs of legs that grew smaller in size as they got farther from the head.

The fossil contains not only a preserved nerve cord, but individual nerves—the first time scientists have ever come across such a minute level of detail in a fossil of this age. Which means this fossil (also known as specimen YKLP 12026) gives researchers a one-of-a-kind insight into how the nervous system of arthropods—animals with segmented bodies, exoskeletons, and jointed appendages, otherwise known very scientifically as “creepy crawlies”—evolved.

Cambrian nervous system fossil comparison

Image credit: Jie Yang (Yunnan University, China) (left) and Javier Ortega-Hernández (University of Cambridge, UK) (right).

Chengjiangocaris kunmingensis itself lived through an extremely important evolutionary event known as the Cambrian explosion about half a billion years ago, during which most of the major animal groups made their first appearance in the fossil record.

“This is a unique glimpse into what the ancestral nervous system looked like,” said study co-author Dr Javier Ortega-Hernández, of the University of Cambridge’s Department of Zoology, in a statement. “It’s the most complete example of a central nervous system from the Cambrian period.”

Image credit: Jie Yang (Yunnan University, China).

Image credit: Jie Yang (Yunnan University, China).

The brains of the operation

Finding any preserved soft tissue is extremely rare; the vast majority of recovered fossils consist of bone or other hard body parts, like the exoskeleton—since soft tissue tends to degrade before it can be preserved.

Up until now, though, researchers have come some soft-tissue nervous system specimens from animals roughly contemporaneous with C. kunmingensis—but most of these have been fossilized brains, or more often than not just the profiles of fossilized brains. The Cambridge researchers, however, had discovered five specimens lacking brains, but with preserved ventral nerve cords (like a spinal cord, only running down the belly of the beast).

And, after careful preparation of specimen YKLP 12026—which involved chipping away at the rock surrounding the fossil using a fine needle—a close examination revealed that not only was its nerve cord preserved, but “delicate nerve roots” about one five-thousandth of a millimeter in length as well, according to the paper in Proceedings of the National Academy of Sciences.

“These delicate fibres displayed a highly regular distribution pattern, and so we wanted to figure out if they were made of the same material as the ganglia that form the nerve cord,” said Ortega-Hernández.

“Using fluorescence microscopy, we confirmed that the fibres were in fact individual nerves, fossilised as carbon films, offering an unprecedented level of detail. These fossils greatly improve our understanding of how the nervous system evolved.”

Daddy?

Perhaps the most exciting part of this discovery to the Cambridge researchers, however, is what this find means in regards to the evolution of certain animals.

For example, there seem to be some modern animals with similar nervous system structure to C. kunmingensis: Namely, priapulids* (penis worms) and onychophorans (velvet worms).

However, other animals down the line aren’t quite so similar. For example, dozens of nerves were lost over time in tardigrades (“water bears,” which turn into glass when dehydrated) and modern arthropods—which suggests that evolutionarily, simplification played a major role in the progression of the nervous system.

But perhaps the most striking part of the discovery is what is different between modern animals and 520-million-year-old C. kunmingensis: Its particular preserved nerve cord is a structure that is otherwise unknown in living organisms.

“The more of these fossils we find, the more we will be able to understand how the nervous system – and how early animals – evolved,” said Ortega-Hernández.

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Image credit: Jie Yang (Yunnan University, China).

*Named for the Greek and Roman god Priapus, who had an eternal erection. Read a bit more about him here (NSFW–penises.)

Scott Kelly departs ISS Tuesday, marking end of Year In Space mission

After spending 340 consecutive days on the International Space Station, NASA astronaut Scott Kelly is scheduled to mark the beginning of the end of his Year In Space mission as he leaves the orbiting laboratory Tuesday and begins his journey back to good ol’ Planet Earth.

On Monday afternoon, Kelly will hand over space station command to Tim Kopra in a Change of Command Ceremony, NASA said, and at 4:15 on Tuesday, he will bid farewell to the station. He is scheduled to undock shortly after 8pm Eastern time, and will officially come back to Earth on Wednesday. Live coverage of his return to Houston is schedule to begin at 11:45pm.

Kelly, who traveled to the ISS as part of the Expedition 26 crew in March 2015, set a new record for the most time spent in space by an American during his time on the station, breaking the previous mark of 215 consecutive days set by NASA astronaut Michael López-Alegría in 2006-07.

When combined with Kelly’s three previous missions, he will have spent a total of 540 days in orbit upon his return (barring delays, of course). Over the course of the past year, he could have witnessed up to 10,000 sunrises and sunsets from space, as the ISS traveled around the Earth at speeds of up to 17,000 miles per hour, according to the New York Times.

Sadly, it could be years before the findings are published

Of course, the Year In Space mission is about much more than breaking records. During the course of his 340-day stint on the space station, Kelly traveled close to 144 million miles, or approximately the distance an astronaut would have to travel to reach Mars.

NASA monitored his health the entire time alongside his twin brother Mark, who remained on Earth so that their vital statistics and other important biological data could be compared and contrasted to see what impact such an extended period in space has on the human body. That included collecting samples of their blood, urine, and feces, Wired noted.

“One of the biggest hurdles of getting to Mars is ensuring humans are ‘go’ for a long-duration mission and that crew members will maintain their health and full capabilities for the duration of a Mars mission and after their return to Earth,” explained NASA.

Before the year-long mission, scientists had been able to observe and collect information on how the body responded to a six-month stay in low gravity, but this marks the first time that were able to do so for a longer period of time. Their findings have and will continue to provide new insight into how a person’s vision, bone structure and muscle tone would be affected during a mission to Mars.

While doctors plan to give Kelly a check-up upon his arrival and will discuss the Year in Space mission during a Friday news conference, the US space agency warned that it will be at least six months and possibly more than five years before any results from the research ends up published in scientific journals – especially since some of the urine and stool samples will remain onboard the ISS until they can be brought back to Earth on the SpaceX Dragon spacecraft.

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Image credit: Scott Kelly/NASA

Extensive Jurassic-era fossil site discovered in Patagonia

A massive Jurassic-era fossil site that spans 23,000 square miles (60,000 square kilometers) in southern Argentina and which is home to fossils between 140 and 160 million years old has been officially announced through the publication of a new study in the journal Ameghiniana.

According to AFP and India Times reports, the site was originally discovered in Patagonia four years ago, but its existence is only now being announced by the paleontologists behind the find, who believe that they were able to locate the fossils due to recent erosion in the region.

Geologist Juan Garcia Massini from the Regional Center for Scientific Research and Technology Transfer (CRILAR), who led the team behind the discovery, told AFP that “no other place in the world contains the same amount and diversity of Jurassic fossils.”

Garcia Massini said that the fossils were preserved very quickly – in some cases, less than a day – and Ignacio Escapa of the Egidio Feruglio Paleontology Museum added that the paleontologists were able to discover “a wide range of micro and macro-organisms” at the site, which is located along the Deseado Massif mountain range in Patagonia’s Santa Cruz Province.

Discovery is the latest to shed new light on Jurassic-era creatures

“You can see the landscape as it appeared in the Jurassic – how thermal waters, lakes, and streams as well as plants and other parts of the ecosystem were distributed,” Garcia Massini told the AFP. “You can see how fungi, cyanobacteria and worms moved when they were alive.”

Because the fossils were preserved so quickly, they are in excellent condition, and the research team believes that each rock that they recovered could lead to a new discovery, which means that this fossil site should continue to bear fruit in the weeks and months ahead.

The publication detailing their findings comes just weeks after researchers identified a Jurassic age insect whose habits and physical appearance closely resemble that of a butterfly, but which predated the first members of the superfamily Papilionoidea by about 40 million years in a case of convergent evolution, where two species acquire similar characteristics independently.

The recently-identified creature, whose discover was detailed earlier this month in Proceedings of the Royal Society: B, was identified as an extinct “lacewing” called Oregramma illecebrosa, according to reports published at the time. It was a member of the genus kalligrammatid and is distantly related to modern-day insects such as fishflies, owlflies, and snakeflies.

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Image credit: Thinkstock

New two-dimensional material could be more useful than graphene

Researchers from the University of Kentucky Center for Computational Sciences have developed a new one-atom thick material that could provide a light, stable and inexpensive alternative to the carbon allotrope graphine, with the added bonus of being a semiconductor.

As UK physicist Madhu Menon and colleagues from Germany and Greece reported Monday in Physical Review B, Rapid Communication, the new material is made from the abundant elements silicon, boron, and nitrogen, and unlike many other graphene alternatives, is extremely stable.

Menon’s team used theoretical computations to demonstrate that by combining these particular elements, they could potentially create a one-atom thick, 2D material with adjustable properties that would allow it to be used in applications that graphene is not suited for. They even showed that it could be heated to 1,000 degrees Celsius without its bonds disintegrating.

The study authors combined silicon, boron and nitrogen atoms in a hexagonal pattern similar to graphene in order to form a planar structure. However, each of the three elements have different sizes and different bonds connecting them, meaning that unlike graphene, the hexagons found in the new material are unequal, they explained in a statement.

Combining the best features of graphene and TMDCs

Touted as the strongest material on Earth, graphene is a carbon-allotrope that is about 100 times stronger than the most durable steel. However, it is not a semiconductor, and therefore its uses in digital technology are somewhat limited. Scientists searching for alternatives have created a new class of three-layer materials called transition-metal dichalcogenides (TMDCs).

TMDCs are semiconductors and can more easily be made into digital processors, but they tend to be bulkier than graphene and are made of less-abundant and more expensive materials. The UK-led team set out to find a better alternative that is light, inexpensive, made from readily available elements from the first two rows of the Periodic Table, and which was a semiconductor.

The material they came up with is metallic, but could become a semiconductor by attaching other elements on top of the silicon atoms. Also, since it contains silicon, it could easily be integrated into currently technology based on that element, which would allow tech companies to phase-out silicon slowly rather than being forced to eliminate it all at once. Furthermore, unlike silicine and other graphene alternatives, it is stable, has a flat surface and will remain 2D.

“We are very anxious for this to be made in the lab. The ultimate test of any theory is experimental verification, so the sooner the better!” Menon said in a statement. “This discovery opens a new chapter in material science by offering new opportunities for researchers to explore functional flexibility and new properties for new applications.”

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Image credit: Madhu Menon/University of Kentucky

Researchers use tranatula venom to make new type of painkiller

People like to say that what doesn’t kill you makes you stronger, but this phrase takes on a whole new light in view of a new discovery: That the venom from certain tarantulas might be turn out to be a new breed of painkiller.

Millions of people across the world live with chronic pain—affecting more people than cancer, diabetes, heart attack, and stroke combined. Moreover, chronic pain is both a physical and emotional condition, leading to isolation, immobility, and several mental disorders, especially including depression.

Of course, the current solution is generally the prescription of pain medications, which often provide little relief, cause intense drowsiness, and are highly addictive—meaning many are searching intensely for something better to help people manage their pain.

A new type of painkiller

Now, as announced at the Biophysical Society’s 60th Annual Meeting, a group of researchers from the University of Queensland in Brisbane, Australia may have just the solution: venom from the Peruvian green velvet tarantula, Thrixopelma pruriens.

Well, maybe not all of the venom, but rather ProTx-II, a peptide toxin, which is found within it. ProTx-II is extremely potent as a painkiller, while being highly selective in regards to which receptor it works on— Nav 1.7, an important pain receptor.

“It binds to the pain receptor located within the membrane of neuronal cells,” said Sónia Troeira Henriques, senior research officer at the University of Queensland’s Institute for Molecular Bioscience, in a statement, “but the precise peptide-receptor binding site and the importance of the cell membrane in the inhibitory activity of ProTx-II is unknown.”

So to help clarify how the structure of ProTx-II affects its function, the team started by “exploring the structure, the membrane-binding properties, and the inhibitory activity of ProTx-II and a series of analogues,” said Henriques.

To this end, the team used nuclear magnetic resonance (NMR) spectroscopy to explore the 3D shape of ProTx-II, in order to determine whether its structure was a key player in how it inhibits the pain receptor. Further, they used a variety of techniques to characterize the interactions between the molecule and the membrane of neurons to figure out how different properties of ProTx-II affected its interaction with the pain receptor.

“Our results show that the cell membrane plays an important role in the ability of ProTx-II to inhibit the pain receptor,” said Henriques. “In particular, the neuronal cell membranes attract the peptide to the neurons, increase its concentration close to the pain receptors, and lock the peptide in the right orientation to maximize its interaction with the target.”

The group noted that most studies before now have ignored how the cell membrane of neurons might affect the efficacy of venom toxins. Theirs in particular is the first to examine how the membrane-binding properties of ProTx-II is important for its efficacy in blockin the Nav 1.7 pain receptor—opening new doors for the future of pain management.

“Our work creates an opportunity to explore the importance of the cell membrane in the activity of peptide toxins that target other voltage-gated ion channels involved in important disorders,” said Henriques.

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Image credit: Thinkstock

Biomedical researcher conducts first real-time scientific study

A scientist from the University of Toronto will be the first biomedical researcher ever to do a very simple—but potentially game-changing thing: She will share her research notes in real time to other researchers and the general public, in hopes of accelerating research on Huntington’s disease.

“This should drive the process faster than working alone,” explained the researcher, Rachel Harding, in a statement. “By sharing my notes, I hope that other scientists will critique my work, collaborate, and share data in the early stages of research.”

But more than improving her personal work on Huntington’s disease, having open and collaborative research could help researchers worldwide. Many scientists work in relative isolation, and only publish their work after years of research yield a positive result.

Another important piece of this method comes from what Harding doesn’t discover. Researchers need to know what hasn’t worked so they don’t spend time and money replicating the same negative results. Moreover, by publishing research live, scientists working on the same kind of research at the same time can feed off each other, learning from each other’s mistakes and suggesting new ideas that may have otherwise never come up.

Testing a new idea about testing ideas

Harding herself has already taken the first steps towards this sort of collaboration, by publishing her raw data and details of her research on the CERN open digital repository Zenodo. Further, she is posting regular updates written for people who aren’t research scientists on her blog Lab Scribbles.

“By providing access to raw data as well as the enabling research tools, we will help the community perform more robust experiments, which will accelerate the drug discovery process and potentially the development of new medicines,” said Aled Edwards, a Professor in the University of Toronto’s Department of Medical Biophysics.

In terms of Huntington’s disease, this sort of research may finally help us understand the actual mechanisms behind the disease. It’s generally known that a mutation in the huntingtin gene is what causes the disease, which leads to progressive cognitive decline and physical deterioration starting around ages 35 to 50 in those with the gene, but the specifics have eluded scientists for years.

For example, while genes make changes in the body by producing proteins, no one actually knows what the exact structure of the huntingtin protein is—a key part to understanding how it leads to the disease.

“This is a very large protein and difficult to study. It is significantly larger than most other proteins in the cell,” said Harding.

But by sharing her notes and discoveries with everyone, though, Harding has hope that this will change.

“This is what research is really like,” she said. “It’s not so much about big breakthroughs and polished results, but about incrementally getting closer to an answer. I think by being more open about our research we can all learn how to do the experiments better.”

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Pictured is Rachel Harding in her lab. Image credit: University of Toronto

IBEX data helps shed new light on the interstellar magnetic field

Using simulations and data collected by NASA’s Interstellar Boundary Explorer (IBEX), a team of researchers has determined the strength and direction of the magnetic field located beyond the heliosphere, or the large magnetic bubble that surrounds our planet’s solar system.

As the US space agency explained in a statement, IBEX detected an oddity shortly after its 2008 launch. It found a thin sliver of space that contained more streaming particles than any other part of the sky. At the time, the origins of this unusual ribbon were unknown, but scientists saw it as a way to potentially observe phenomena located beyond our part of the galactic neighborhood.

Now, in a new study published this month in the Astrophysical Journal Letters, Eric Zirnstein, a space scientist at the Southwest Research Institute (SwRI) in San Antonio, Texas, and colleagues build upon one particular theory that claims that the particles in the IBEX ribbon are actually bits of solar material that are reflected back towards us after reaching the edge of the heliosphere.

ibex

The IBEX ribbon in question.

The heliosphere is filled with solar winds, which are the constant outflow of ionized gas (plasma) from the sun. Once these particles reach the edges of the magnetic bubble, the theory proposes that some of them are reflected back towards the sun as neutral atoms following a complex series of charge exchanges, Zirnstein explained. This results in the creation of the IBEX ribbon.

Breaking down how the process works

The simulations and observations analyzed by the Zirnstein’s team revealed that this particular process, which takes between three and six years to complete on average, is the “most likely” explanation for the IBEX ribbon. But what specifically causes this plasma to be reflected towards the sun?

Beyond the heliosphere, the scientists explained, is a region of space known as the interstellar medium. Here, there exists plasma that has a different velocity, temperature and density than the ionized gas that makes up the solar wind, as well as with neutral gases. These materials interact at the outer edge of the heliopshere to create a region known as the inner heliosheath.

On the inside of the inner heliosheath is the termination shock, or the point where the solar wind slows down to subsonic speeds due to interactions with the local interstellar medium. This causes compression, heating, and a change in the magnetic field. On the outside of the heliosheath is the heliopause, or the boundary separating the solar wind and denser interstellar medium.

Some solar wind protons that reach this boundary will gain an electron, making them neutral and allowing them to cross the heliopause. Once they reach the interstellar medium, that electron can once again be lost, causing them to gyrate around the interstellar magnetic field. In some cases, if the particles gain another electron under the right circumstances, they can again be fired into the heliosphere, travel back to Earth, and collide with the IBEX detector, according to NASA.

These particles contain information about their interactions with the interstellar magnetic field, and that analyzing that data “provides a nice determination” of the “strength and direction,” and other characteristics of that region of space, said Zirnstein.

Simulations match up with Voyager observations – in most cases

The characteristics of the interstellar magnetic field determine the direction of the various ribbon particles shot back to Earth, the researchers said. Simulations indicate that the most energetic of the particles originate from a different part of space than the least energetic ones, which provides new insight into how the interstellar magnetic field interacts with the heliosphere.

As part of their research, Zirnstein’s team used observations to create simulations of the IBEX ribbon’s origin. These simulations correctly predicted the locations of neutral ribbon particles of different energies, and created an interstellar magnetic field that, in most cases, agreed with both the measurements collected by Voyager 1 and other observed properties of the region.

Some of the simulations did not line up with data points were Voyager 1 and Voyager 2 crossed the termination shock, but the study authors believe that these discrepancies could be caused by a stronger-than-expected influence from the solar cycle, which would in turn alter the strength of the solar wind and change the distance to the termination shock in the probes’ directions.

“The new findings can be used to better understand how our space environment interacts with the interstellar environment beyond the heliopause,” said Eric Christian, a scientists working on the IBEX program scientist at the Goddard Space Flight Center in Maryland who was not part of the study. “In turn, understanding that interaction could help explain the mystery of what causes the IBEX ribbon once and for all.”

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Image credit: NASA/IBEX/Adler Planetarium

Think your cat is in pain? Check for these 25 signs

Is something different about your cat’s behavior, but you don’t know if it means something’s wrong?

Well, a new study in the journal PLOS ONE may be able to help as a team of researchers developed a list of 25 signs that indicate your kitty is in pain.

cat pain

The list was developed by notable academics and clinical experts from around the world with specialties including internal medicine, anesthesiology, oncology, dermatology, and neurology.

“Both owners and veterinarians are clearly able to recognize many behavioral changes in cats which relate to pain,” Daniel Mills, professor of veterinary behavioral medicine at the University of Lincoln in the United Kingdom, said in a news release. “However, owners may not always recognize the clinical relevance of what they see.

“For example, they may view the changes as an inevitable part of natural ageing and not report them to the vet as a concern, or at least not until the behaviors become quite severe,” Mills continued. “We hope that having an agreed list of more objective criteria, which relates to specific signs of pain, could improve the ability of both owners and vets to recognize it.”

The expert panel classified signs in two different ways: ‘sufficient’ and ‘necessary’. Seeing one of the sufficient signs, the experts said, means the cat is in pain – while the necessary signs must be present for pain to even be considered.

The study team used behavior analysis to identify 25 key ‘sufficient’ signs, like not grooming or changes in feeding behavior and difficulty to jump. The team said their results indicate evaluating a set of behaviors will be much more reliable than looking for just one single symptom.

“Throughout the study, we consulted a variety of international experts so that we could be sure the signs were universal indicators of pain,” Mills said. “By creating this core set of signs, we lay the foundation for future studies into the early detection of pain in cats, using scales which are crucially based on natural, non-invasive, observations.”

“Cats are notorious for not showing that they are in pain, and the more that we can find out what the signals are, then the sooner we can get them to the vets for diagnosis and treatment,” commented Caroline Fawcett, chairman of the UK charity Feline Friends.” There is a long way still to go before the more subtle signs can be identified, but we are really excited about progress to date.”

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Image credit: Thinkstock

New solar cell is so thin and light it can rest on a bubble

The field of solar energy took a giant leap forward today, as researchers from MIT created the thinnest, lightest solar cells ever made—so light, in fact, that they can rest on a bubble.

As described in the journal Organic Electronics, the team has successfully completed a proof-of-concept test of a new technique for making solar cells—one that could lead to solar cells finding their way to hats, shirts, cell phones, or even simple balloons.

How did they achieve this?

The key, according to MIT associate dean for innovation and co-author Vladimir Bulović, is to cut down on the number of steps needed to make a cell—by making the solar cell, the substrate that supports the cell, and the protective coating that shields the cell from the environment in a single process.

“The innovative step is the realization that you can grow the substrate at the same time as you grow the device,” said Bulović in an MIT statement.

Furthermore, because the substrate is made simultaneously and is never removed from the vacuum chamber where the cell is produced, it has minimal exposure to contaminants like dust—which can lower a solar cell’s performance.

In this particular experiment, the substrate and overcoat were both made from a common flexible polymer known as parylene—which is a commercially available coating used to protect circuit boards from environmental damage. Meanwhile, they used an organic material known as DBP as the primary light-absorbing layer, although the team emphasized that these materials were only some of the potential options—as their in-line substrate manufacturing process is the key aspect here. 

Both the substrate and the solar cell are “grown” using vapor deposition techniques at room temperature—a sharp break from conventional methods, which required both high temperatures and harsh chemicals to make the cell. The parylene film is first deposited on a carrier material—like glass, in this experiment—and after the cell is fabricated, it’s lifted from the carrier using a frame made of flexible film. 

Or, in short: “We put our carrier in a vacuum system, then we deposit everything else on top of it, and then peel the whole thing off,” said MIT research scientist Annie Wang.

The end result: A solar cell that can rest on a soap bubble without popping it. Interestingly, this might actually be too thin to be practical (“If you breathe too hard, you might blow it away,” said MIT doctoral student Joel Jean)—but it’s a huge step nonetheless. The solar cells are ultra-thin—1/50th the thickness of a human hair—but convert sunlight with one of the highest power-to-weight ratios ever achieved, at about 6 watts per gram.

Which means that these solar panels could be added to just about anything, but especially objects where weight is a huge consideration—like spacecraft.

Of course, there’s still a long way to go from here.

“We have a proof-of-concept that works,” said Bulović. But the next question is, “How many miracles does it take to make it scalable? We think it’s a lot of hard work ahead, but likely no miracles needed.”

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Image credit: Joel Jean and Anna Osherov, MIT

Newly discovered enzyme could be the key to anti-aging products

While modern-day snake-oil salesmen pitch products promising to combat the effects of aging and keep skin looking young in infomercials, researchers from Newcastle University in the UK have identified activity in human skin cells that could actually deliver on such promises.

In a study published online in the Journal of Investigative Dermatology, Mark Birch-Machin, a Professor of Molecular Dermatology at Newcastle University, and his colleagues explained that they had identified that a key metabolic enzyme in skin cells becomes less active with age.

Known as mitochondrial complex II, this enzyme is found in the so-called batteries of the cells and plays a key role in keeping skin smooth and supple, the researchers explained. The discovery could lead to the development of effective anti-aging treatments and cosmetics which counteract the decline in the enzyme’s activity level.

“As our bodies age we see that the batteries in our cells run down, known as decreased bio-energy, and harmful free radicals increase. This process is easily seen in our skin as increased fine lines, wrinkles and sagging appears,” Professor Birch-Machin said in a statement.

“Our study shows, for the first time, in human skin that with increasing age there is a specific decrease in the activity of a key metabolic enzyme found in the batteries of the skin cells,” he added. “This enzyme is the hinge between the two important ways of making energy in our cells and a decrease in its activity contributes to decreased bio-energy in ageing skin.”

Discovery could lead to products that can keep skin looking young

Professor Birch-Machin, who co-led the research with Dr. Amy Bowman from his research team at the university, said that the work marks the first time that a biomarker that could be a target for anti-aging treatments has been identified and that it could lead to specialized cosmetics or creams tailored to different ages or types of skin pigmentation.

In addition, it could lead to a better understanding of how other cells and organs in the body age, potentially leading to the development of new therapies for age-related diseases, Professor Birch-Machin said. The research could “address the ageing process elsewhere in our bodies,” he added.

The study authors measured complex II activity in 27 donors between the ages of six and 72. In each case, a sample was collected from an area of sun-protected skin, and a variety of techniques were used to measure the activity of enzymes in the mitochondria, which helps provide energy to the skin cell. Both the upper (epidermis) and lower (dermis) levels of skin were studied.

They observed a significant age-related decline in complex II activity per unit of mitochondria in cells derived from the dermis, and discovered that this was due to a decreased amount in enzyme protein. As such, the decrease was only observed in those cells that had stopped proliferating, the researchers said. Further research will be needed to fully understand how this affects the skin and to search for ways that this could be used to combat aging in human skin.

“It has long been thought that mitochondria play an important role in the aging process, however the exact role has remained unclear,” Dr. Bowman said. “Our work brings us one step closer to understanding how these vital cell structures may be contributing to human aging, with the hope of eventually specifically targeting areas of the mitochondria in an attempt to counteract the signs of aging.”

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Image credit: Professor Mark Birch-Machin

 

Origins of mystery meteorite unveiled in new study

A Florida State University student has shown a piece of ancient meteorite to have a much more explosive and fascinating history than previously thought, Phys.org reports.

Jonathan Oulton, a 2015 FSU graduate working with Earth, Ocean & Atmospheric Science Professor Munir Humayun, studied pieces of a meteorite called Gujba, and found that it likely formed at the time planets in our solar system were in their early development.

Humayun and Oulton conducted in-depth chemical analysis on the samples using sophisticated lasers and mass spectrometers at the FSU-headquartered National High Magnetic Field Laboratory.They were able to refute the existing theory that the meteorite was largely formed from the dust of the solar system, and replace it with one that hints at a more complex geological history.

A more explosive history

The pair and their collaborators argue that Gujba formed from the molten debris produced when a large metallic body smashed into another planet, in an impact that destroyed them both.

Chemical traces preserved in Gujba suggested that the planet might have been even larger than the asteroid 4 Vesta, which has a diameter of around 326 miles, and is one of the largest bodies in the asteroid belt.

“People used to say that meteorites like Gujba were the building blocks of the solar system,” Humayun said. “Now, we know it’s the ‘construction debris’ of the planets, to borrow a phrase from Ed Scott of the University of Hawaii.”

“In a broad sense, people have been trying forever to understand how we got here,” Oulton added. “Although this doesn’t get to that directly, this research gives us a greater understanding of the physical chemistry of everything that occurred at the time the Earth formed.”

The research will be published in an upcoming issue of Geochimica et Cosmochimica Acta.

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Image credit: Florida State University

NASA releases stunning image of Pluto’s North Pole

NASA researchers have made yet another a startling discovery about the geology of Pluto, as a newly-released image captured by the New Horizons spacecraft has lead to the discovery of wide frozen canyons located near the dwarf planet’s north polar region.

The enhanced color image, publicly unveiled by the US space agency Thursday in a statement, shows long canyons that run vertically along a portion of the region informally known as Lowell Regio. The widest of these canyons is roughly 45 miles (75 kilometers) wide and is located close to Pluto’s north pole, and is shaded yellow in one of the newly-released pictures.

Running roughly parallel to that canyon are two others, one to the east and one to the west, that are colored green in the photograph. Each of these geological features are approximately 6 miles (10 km) wide. Furthermore, NASA scientists note that the degraded walls of these canyons seem to indicate that they are far older than those found elsewhere on the dwarf planet’s surface.

NASA's annotated image of Pluto's north pole

Credit: NASA

The polar canyons also contain what appears to be evidence that Pluto was once home to tectonic activity, and the largest canyon was also found to contain a shallow, winding valley (indicated by the blue highlights on the image) that runs the entire length of its floor. Another valley (pink) can be found towards the bottom-right of the photograph, the researchers noted.

Photo also reveals a previously-undiscovered high-elevation area

Nearby terrain located to the bottom right of the canyons appears to have been covered by some type of substance that obscures some of the landscape’s smaller topographic features, and several 45 mile wide, irregularly shaped pits (red in color) stretch 2.5 miles across the region.

According to the agency, these pits could be areas where subsurface ice melted or sublimated from below, causing the ground to collapse and scar the terrain. Furthermore, the area’s color and composition are said to be unusual, as it contains areas of higher elevation (which show up yellow in the enhanced-color image) that have not been seen previously on Pluto.

The yellow-colored terrain gives way to a bluish-gray at lower elevations and latitudes, and the infrared instruments on New Horizons found abundant methane ice throughout Lowell Regio but little to no nitrogen ice. Will Grundy, head of the New Horizons composition team from Lowell Observatory in Flagstaff, Arizona, said that the yellow terrain “may correspond to older methane deposits that have been more processed by solar radiation than the bluer terrain.”

The image that served as the basis for these new observations was captured using New Horizons’ Ralph/Multispectral Visible Imaging Camera (MVIC) instrument. It was taken in a resolution of about 2,230 feet (680 meters) per pixel from a distance of 21,100 miles (33,900 km) from Pluto’s surface on July 14, 2015 – less than an hour before the spacecraft’s closest approach to the dwarf planet.

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Image credit: NASA

Ebola treatment using antibody from survivor approved for further trials

An antibody isolated from a human survivor of the Ebola virus has proven effective at protecting non-human primates from the effects of the disease up to five days after infection, according to a pair of new studies published Thursday in the online edition of the journal Science.

The protein in question, a single monoclonal antibody that attacks viral pathogens, was found in blood samples belonging to a survivor of the 1995 Ebola outbreak in Kikwit, a city in Bandundu Province, Democratic Republic of the Congo, the US National Institute of Allergy and Infectious Diseases (NIAID) scientists behind the research confirmed in a statement.

The NIAID team analyzed the blood samples and found that the survivor had retained antibodies against the disease. Colleagues at the Institute for Research in Biomedicine in Switzerland were able to isolate specific proteins that could potentially be used to treat Ebola, and experts from the Army Medical Research Institute of Infectious Diseases then tested the antibody on primates.

Specifically, they administered a lethal dose of Zaire ebolavirus to four rhesus macaques. Then, five days later, then treated three of the macaques with once-daily intravenous injections of the antibody, mAb114, for three consecutive days. While the untreated creature showed signs of the disease and eventually died, those receiving the antibody remained symptom free.

Testing can now begin on humans, but some doubt its effectiveness

Researchers from the NIAID and Dartmouth College studies how the antibody neutralized the virus, and found that it attaches itself to the core of the Ebola glycoprotein, preventing the virus from interacting with a receptor on human cells. It had previously been believed that this region of the pathogen was too well hidden and could not be reached by antibodies.

The mAb114 antibody is said to be the first to demonstrate that it can neutralize the Ebola virus by blocking its interaction with cell receptors. Combined with evidence that there is a novel site of vulnerability on the Ebola virus, the evidence suggests that this could prove to be an effective way to treat the condition and warrants further exploration.

The results of their research are detailed in a pair of studies (Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody” and “Structural and molecular basis for Ebola virus neutralization by protective human antibodies) currently available on the Science website, and the antibody will now be able to advance to testing on humans.

“On the face of it, this is really exciting work, but there are still uncertainties about how effective this approach might be,” Nottingham University molecular virology professor Jonathan Ball told The Guardian. “The virus will find it easier to mutate and escape the killing effects of a single antibody compared to a mixture of three, each targeting a different part of the virus.”

“The antibody cocktails can protect monkeys even when they are given after symptoms develop. This is really important, because humans usually only get diagnosed after symptoms appear,” he added. “So if the virus doesn’t mutate to stop the antibody working and it works after symptoms develop then it truly is a big step forward.”

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Image credit: NIAID

Rare 11,000 year old pendant is the oldest Mesolithic art ever found in the UK

An 11,000-year-old pendant discovered in North Yorkshire was nearly mistaken for a regular piece of rock, but it turned out to be the rarest item of its kind ever found—because there’s nothing else quite like it.

The triangular pendant, which was crafted from a single piece of shale, was found by archaeologists at an Early Mesolithic site in England known as Star Carr. Measuring roughly 1.22 by 1.38 inches (31 by 35 mm), it features the earliest known Mesolithic (Middle Stone Age) art in all of Britain—a series of lines that have been variously interpreted as a tree, a map, a leaf, or simple tally marks.

pendant

Credit: Nicky Milner et al.

Not only does the pendant contain the earliest Mesolithic art ever found in the UK, but engraved pendants from the same time period are extremely rare globally—and no other pendants found have been made of shale.

“It was incredibly exciting to discover such a rare object,” said lead researcher Nicky Milner, of the Department of Archaeology at York, in a statement. “It is unlike anything we have found in Britain from this period. We can only imagine who owned it, how they wore it and what the engravings actually meant to them.”

Almost missed and forgotten

Scientists almost missed the pendant entirely. When it was drawn from some lake edge deposits in Star Carr, it looked like a natural stone, as the perforation (the hole presumably through which string was strung) had been filled in with mud. Further, the engravings—which are hard to see when the pendant is clean—were obscured.

But, after cleaning it up, they realized they had found something immensely important. According to the study, which is published in Internet Archaeology, the team then set to work to study the engravings. Using a variety of digital microscopy techniques, they were able to generate high res images of the art, which they discovered has interesting relations to art outside of the UK.

“This exciting find tells us about the art of the first permanent settlers of Britain after the last Ice Age,” said Dr. Chantal Conneller, the co-director of the excavations at The University of Manchester.

“This was a time when sea-level was much lower than today. Groups roamed across Doggerland (land now under the North Sea) and into Britain. The designs on our pendant are similar to those found in southern Scandinavia and other areas bordering the North Sea, showing a close cultural connection between northern European groups at this time.”

How was the pendant used?

The researchers also tested the pendant to establish whether it had been strung and worn, or whether pigments had been added to it to make the artwork more prominent. There doesn’t appear to be any traces of pigment left on the stone—if there was any on it to begin with. Furthermore, there is little to no wear around the perforation, which would be expected if the pendant was used as a necklace.

Although that doesn’t necessarily mean anything.

“[I]t remains possible that the pendant was suspended and worn, but for such a limited duration of time as to leave no traces,” wrote the authors in the paper. “Indeed, it is also possible that it was intended for a single use, such as a ceremony, which is unlikely to leave any signatures of use at all.”

In fact, the idea of it being used for ceremonial purposes is something the researchers consider as a fairly intriguing option.

“One possibility is that the pendant belonged to a shaman – headdresses made out of red deer antlers found nearby in earlier excavations are thought to have been worn by shamans,” said Milner. “We can only guess what the engravings mean but engraved amber pendants found in Denmark have been interpreted as amulets used for spiritual personal protection.”

Regardless of its use, the Star Carr shale pendant is an extraordinarily rare find—and has already added new knowledge to the books.

“The discovery of the pendant is a sensational find,” said Duncan Wilson, Chief Executive of Historic England—which both contributed to and part-funded the excavation and research publication.

“Star Carr is an internationally important ‘at risk’ site, which is why we have provided substantial financial support for the excavation and assistance through the input of our specialist archaeological and archaeological science teams. The results have exceeded our expectations and will help rewrite the story of this long and complex, but little understood early prehistoric period.”

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Credit: Nicky Milner et al.

Study maps massive methane gas leaks throughout Los Angeles Basin

Researchers from the University of California, Irvine have discovered hundreds of methane-emitting hotspots throughout Los Angeles, Orange and Riverside counties, according to a new study published this week in the Journal of Geophysical Research: Atmospheres.

Lead author Francesca Hopkins and a team of atmospheric scientists conducted a mobile survey along the Los Angeles Basin to identify the highest emitters of the greenhouse gas, which is the second-biggest contributor to climate change behind carbon dioxide, they explained.

The survey “identified numerous methane hot spots that could be targets for these mitigation activities,” Hopkins, a former student at UCI who is now an environmental scientist at the Jet Propulsion Laboratory (JPL) in Pasadena, said in a statement.

She and her colleagues used a cargo van equipped with special instruments they used to measure various greenhouse gases, including methane and CO2, along a several-hundred mile stretch of the Los Angeles Basin. They found a total of 213 methane hotspots, including a so-called “clean port” refueling center in Long Beach, power plants and water treatment centers.

Greenhouse gas sources include cattle, landfills, fueling stations

Furthermore, Hopkins’ team recorded elevated methane levels throughout the basin. Two-thirds of that methane came from fossil fuel-related sources, they said, and other known sources of the gas included “cattle, geologic seeps, landfills and compressed natural gas fueling stations.”

The survey was conducted prior to a gas well leak at Aliso Canyon that temporarily forced more than a thousand Porter Ranch residents from their homes, the study authors said, and suggest that there is a persistent cloud of methane lingering over the region. A sampling mast attached to the van’s roof and spectrometers allowed them to continuously collect and analyze air samples.

“Mobile measurements are really important because you can examine the fine-scale structure of variations in methane within neighborhoods and begin to identify the origins,” lead investigator Jim Randerson, UCI Chancellor’s Professor of Earth System Science, said in a  study. “It’s often not possible to pinpoint individual sources with aircraft observations.”

Randerson added that the findings indicate that “natural gas leaks are ubiquitous throughout the Los Angeles Basin,” and that there is a need to “develop a regional partnership with stakeholders to identify the source of these leaks and make a plan for fixing them.” Riley Duren from the JPL Megacities Carbon Project added that it will help experts “gain a much clearer understanding of the problem” of methane sources in municipal areas.

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Image credit: Thinkstock

‘Sperm in a dish’ breakthrough could help treat male infertility

 

In a major breakthrough for male fertility, researchers in China have engineered functioning sperm from mice stem cells.

The scientists converted mouse embryonic stem cells into functional sperm-like cells, which were then inserted into egg cells to generate fertile mouse offspring, according to a study published in the journal Cell Stem Cell.

The researchers said in a statement that their work provides a platform for generating sperm cells that could one day be used to treat male infertility in humans.

stemcelltech

Credit: Zhou, Wang, and Yuan et al./Cell Stem Cell 2016

Reproducing the components of life

“Reproducing germ cell development in vitro has remained a central goal in both reproductive biology and reproductive medicine,” study author Jiahao Sha of Nanjing Medical University, said in a press release. “We established a robust, stepwise approach that recapitulates the formation of functional sperm-like cells in a dish. Our method fully complies with the gold standards recently proposed by a consensus panel of reproductive biologists, so we think that it holds tremendous promise for treating male infertility.”

One significant cause of male infertility is the failure of forerunner cells in the testes to go through a kind of cell division known as “meiosis” in order to create functional sperm cells. Multiple research studies have reported the successful production of germ cells from stem cells, but they did not fully assess the viability of the germ cells or supply proof for all essential key points of meiosis.

Recently, a panel of reproductive biologists offered up gold standard criteria for demonstrating that meiosis has occurred in engineered germ cells. For instance, scientists must show proof of the correct nuclear DNA content at particular meiotic stages, normal chromosome number and organization, and the capacity of germ cells to generate viable offspring. Until now, proving the crucial steps of meiosis have occurred has stayed a main obstacle to the generation of viable sperm and egg cells from stem cells.

Proof of concept in mice

In the new study, researchers began by subjecting mouse embryonic stem cells (ESCs) to a chemical mixture that turned the ESCs into primordial germ cells. Next, the scientists modeled the normal tissue environs of these precursor germ cells by subjecting them to testicular cells along with sex hormones like testosterone.

The study team reported that the ESC-derived cells completely went through meiosis, producing sperm-like cells with correct genetic and chromosomal material. To meet last gold-standard verification of meiosis, the scientists injected their cells into mouse egg cells and placed the embryos into female mice. The embryos developed normally and gave rise to good, fertile offspring.

The scientists said they plan to use their system to investigate the molecular parts controlling meiosis. They said they will also test their strategy in other animals such as primates in anticipation of human research. However, before this process is translated to the clinic, risks must be eliminated and ethical concerns concerning the use of embryonic cells should be considered, the study team said.

“If proven to be safe and effective in humans, our platform could potentially generate fully functional sperm for artificial insemination or in vitro fertilization techniques,” Sha said. “Because currently available treatments do not work for many couples, we hope that our approach could substantially improve success rates for male infertility.”

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Image credit: Thinkstock

Newly discovered Muslim graves are the oldest ever found in France

Three graves discovered in southern France are believed to provide the first archaeological and anthropological evidence of Muslims reaching the region and establishing communities as early as 1,300 years ago, according to research published Wednesday in PLOS One.

Radiocarbon dating on skeletons recovered from the medieval grave sites found that they likely belonged to people who lived sometime during the 7th through 9th centuries, Yves Gleize of the French National Institute for Preventive Archaeological Research (Inrap), Fanny Mendisco from University of Bordeaux, and their colleagues explained in a statement.

grave

Credit: Gleize et al

In addition, Gleize, Mendisco and their fellow researchers found that the burials seem to have followed Islamic rites, in that the bodies were positioned with the head facing Mecca, and they also found genetic evidence suggesting their paternal lineage contains North African ancestry.

Based on their findings, they believe that the bodies recovered from these graves belonged to Berbers who had become part of the Umayyad army during the Arab expansion in North Africa during the 8th century. The findings support historical records indicating that there had been an early Muslim presence in southern Gaul during the early-to-mid 1700s, they added.

Men were buried in accordance with traditional Islamic rites

During the early Middle Ages, a Muslim conquest led to significant cultural and political change in the Mediterranean, and while their presence in the Iberian Peninsula has been well established, the authors noted that there had been little evidence that they traveled north of the Pyrenees. The new graves, found in Nimes, appear to provide proof of early Muslim arrival in France.

“We knew that Muslims came to France in the eighth century but until now we did not have any material evidence of their passage,” Gleize told AFP. The graves were originally discovered by a team of construction workers working on an underground parking garage in 2006, and contained the bodies of three men: one in his 20s, one in his 30s and one in his 50s.

The bones showed no signs that the men were injured in combat, each of the men were laying on their sides facing towards Mecca, in accordance with traditional Islamic burial rites. Two of the men were buried al-lahd, their bodies placed in niches dug into the right side of the grave itself with their backs places against brick, Ars Technica said. The other was buried al-shaqq, directly in a trench that was lined and topped with stones obtained from a Roman wall.

Both kinds of burial practices are still common among Muslims today, and similar burials have been discovered in medieval Islamic communities in Spain, the website added. According to the Daily Mail, this marks the earliest evidence of a Muslim presence in France ever discovered.

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Image credit: Gleize et. al

New bandage prevents infections and improves treatment for burn patients

Most people who pass away following severe burns usually succumb to infections brought on by their immunocompromised state, not the trauma itself, but a new kind of bandage may be able to prevent these fatalities in the future, according to a new Scientific Reports study.

In addition to playing havoc with a victim’s immune system, severe burns can cause the loss of skin on various parts of the body, researchers from the Swiss Federal Institute of Technology in Lausanne (EPFL) explained. The bandages typically used to treat such wounds can be a breeding ground for bacteria, and many of those microbes are resistant to antibiotics, they added.

bandage2

Credit: Murielle Michetti, Swiss Federal Institute of Technology

To combat the problem, the EPFL-led team used a kind of  biodegradable dressing made from animal collagen and quickly-multiplying progenitor cells that was first developed in 2005, and added dendrimers, a kind of molecule which can prevent burn wounds from becoming infected. The new bandage can also help speed up the healing process, they explained in a statement.

Discovery could prevent the need to constantly replace dressing

The researchers focused their efforts on the bacterium Pseudomonas aeruginosa, which they note is the primary cause of infections and death among burn victims. If a collagen bandage is placed on a burn site, a portion of the dendrimers it is infused with migrate to the wound and destroy nearby bacteria, while the others remain in the bandage for protection.

As Dominique Pioletti, the head of EPFL’s Laboratory of Biomechanical Orthopedics, explained in a statement, bandages “are a favorable environment for bacterial growth,” which means that a portion of the dendrimers “have to remain in the bandage to destroy any intruders.”

The technology fills an urgent need for many doctors and burn specialists, said Lee Ann Laurent-Applegate, head of the University Hospital of Lausanne (CHUV) Regenerative Therapy Unit. As she pointed out, treating burns currently requires doctors to “take enormous precautions with our patients,” including changing a patient’s dressing “every day for several months.”

Even doing so “does not stop infections, and we cannot prescribe antibiotics to all patients as a preventive measure for fear of making the bacteria more resistant. With the new bandages, rather than treating infections, we will be preventing them,” Laurent-Applegate added. However, these new bandages will need to undergo further testing before they can be used in hospitals.

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Image credit: Murielle Michetti, Swiss Federal Institute of Technology

Humans sped up evolution in a Canadian lake. How did this happen?

The accidental introduction of crayfish into a lake in British Columbia, Canada, by humans has caused the extinction of two species of fish that had lived there for some 15,000 years—well, sort of.

Life, ah…finds a way, and what has replaced these two fish could have dire consequences for the local environment.

The two fish were similar species of endangered threespine stickleback fish, both of which coexisted peacefully in Enos Lake in BC—until they didn’t.

“When two similar species are in one environment, they often perform different ecological roles,” said co-author Seth Rudman, a PhD student in zoology at UBC, in a statement. “When they go extinct, it has strong consequences for the ecosystem.”

In the case of Enos Lake, one species tended to live in the middle of the lake, where it preyed on zooplankton, while the other lived nearer to the shore and ate mostly waterborne insect larvae. They more or less left each other alone, breeding only with their own species, for thousands of years.

But then, in the early 1990s, American signal crayfish were accidentally introduced to the lake, likely through fishermen who were using them as bait on Vancouver Island.

From then on, the crayfish began to clear-cut the vegetation on the bottom of the lake—forcing the middle-of-the-lake sticklebacks to search for food and mates in the open water above, where the shore-preferring species lived.

Forced together, these two species of fish began to interbreed between 1994 and 1997—and then totally disappeared, leaving behind only a hybrid species of stickleback.

How did this happen?

The current study, which can be found in Current Biology, aimed to figure out just how this human-driven evolutionary process—which is known as reverse speciation (or despeciation)—affected the ecosystem. What is different now that there is one species where two used to be?

As it turns out, the two-species hybrid has lost some of the ecological roles that both fish used to carry out; it spends most of its time near the lakeshore, where it eats large insects—which has led to an increase in the number of small insects coming out of the lake. Moreover, after the advent of the hybrid, there has actually been an effect on the terrestrial ecosystem, as leaves that fall into the lake no longer decompose as quickly as they used to.

In other words, by inadvertently introducing crayfish into Enos Lake, humans have triggered an evolutionary process that has consequences for the ecosystem all around the water—and may accidentally cause more in the future. Reverse speciation is especially likely to happen in “young” species—ones that are, say, thousands of years old instead of millions—and is a process that seems to be on the rise, thanks to humans.

Which means that, down the road, Canada could be facing a huge ecological issue as more and more species disappear into hybrids.

“Much of Canada’s biodiversity, particularly fish in lakes and rivers, are considered to be ‘young’ species that formed in the last 12,000 years or so,” said Rudman. “This type of evolution, known as reverse speciation, happens remarkably quickly and can cause alterations to the ecology of the ecosystem. It means we need to consider evolution in our conservation efforts.”

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Image credit: Ernie Cooper

Climate change benefits the rich more than the poor, study says

Climate change will exacerbate the difference between the richest countries and the poorest countries, according to a new report published in the journal Nature Climate Change.

The study found that climate change will push natural resources toward Earth’s pole and since wealthier countries tend to prioritize resource management, these countries are positioned to reap any potential climate change related rewards.

“What we find is that natural resources like fish are being pushed around by climate change, and that changes who gets access to them,” Malin Pinsky, professor of ecology & evolution at Rutgers University, said in a news release.

The team noted that fish, plants, trees, and other species essential to society are moving out of the temperate zones and in the direction of the poles as global temperatures increase. Researchers also said “inclusive wealth” is the amount of a community’s capital assets – like natural assets and human health – in addition to developed assets like roads, buildings, and industrial facilities. Because climate transformations erratically from place to place, normal assets migrate or reproduce erratically.

How did they come to this conclusion?

To reach their conclusion, the study team used information Pinsky developed in his research of fish migration and put that data into a mathematical algorithm. The study also considered two fictional fishing communities: Northport and Southport. The team was able to show the connection between the shifting of resources and the shifting of wealth due to climate change.

“We tend to think of climate change as just a problem of physics and biology,” Pinsky saod. “But people react to climate change as well, and at the moment we don’t have a good understanding for the impacts of human behavior on natural resources affected by climate change.”

In another recent study, researchers found climate change may affect international air travel. Published in Environmental Research Letters journal, the study found a faster jet stream caused by climate change winds will delay transatlantic flights, resulting in the loss of countless hours and millions of dollars in jet fuel.

“The aviation industry is facing pressure to reduce its environmental impacts, but this study shows a new way in which aviation is itself susceptible to the effects of climate change,” study author Paul Williams, an atmospheric scientist at the University of Reading in the United Kingdom, told The Guardian.

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Featured image: Migratory fish contribute heavily to this phenomenon. Image credit: Thinkstock

The brain judges others in only a few milliseconds, study says

It takes a matter of mere milliseconds after meeting someone for the first time for a person’s brain to determine whether or not that person is likable, according to new research led by University of Freiburg psychologist and neuroscientist Dr. Bastian Schiller.

Dr. Schiller, along with colleagues from the University of Basel and the University of Bern in Switzerland, identified for the first time the subconscious process we use to process social data such as likability or antipathy, and the order in which it does so.

As they explained in the latest edition of the journal Proceedings of the National Academy of Sciences, they used the Implicit Association Test (IAT), a psychological exam which measures the strength of a person’s automatic association between concepts and attributes in memory to gague reactions to ideas, phrases, or cultural trappings.

For example, they administered the IAT to a group of soccer fans, measuring their brain waves using an electroencephalogram as they responded to concepts like “love” or “death” in relation to both the names of the players on their favorite sports teams and those on the opposing squad.

Study of ‘microstates’ could lead to new treatments for social, mental disorders

The goal of the experiment was to study the individual steps used to process information and the duration it took to make subconscious social assessments. They accomplished this by analyzing a series of short phases or “microstates,” during which a neuronal network in the brain is activated to carry out a specific processing step.

Previous research had already determined that reaction times in the IAT were longer when men and women associate foreign groups with positive characteristics. The new study takes things a step further by revealing that the increased reaction time is not the result of additional processing steps. Rather, it is the result of some of the individual steps taking longer to complete.

“This study demonstrates the potential of modern electrical neuroimaging in helping to better understand the origin and time course of socially relevant processes in the human brain,” Schiller explained in a statement. He and his colleagues are currently evaluating the degree to which this discovery could be used to diagnose and treat social deficiencies or other mental issues.

“Superior to other approaches, the microstate approach allowed us to identify and time the entire chain of mental processes as they unfolded during the IAT,” the authors wrote in their new PNAS paper, adding that the findings indicate that “reaction time differences are due to quantitative and not qualitative differences in the underlying mental processes.”

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Image credit: Thinkstock

DNA ‘Trojan horse’ effective against drug-resistant leukemia

Borrowing a page from history, a team of researchers from Ohio State University are working on a biological Trojan horse of sorts that can launch a sneak attack against cancer cells by hiding a commonly-used chemotherapy drug in a capsule made from folded-up DNA.

The packaging technique is known as “DNA origami,” and according to Dr. John Byrd, the chair of leukemia research at the OSU Wexner Medical Center, and mechanical engineering professor Carlos Castro, it has even proven effective at stopping drug-resistant cancer cells in lab tests.

DNA origami had previously been used to overcome drug resistance in solid tumors, but this is the first time that researchers have demonstrated that the technique can also be used on leukemia cells. The early results of their work have been published in the journal Small, and they are now testing the capsule in mice, with the hopes that human trials may soon follow.

In a statement, Castro explained that nanostructures made from DNA have demonstrated “a lot of potential for drug delivery, not just for making effective drug delivery vehicles, but enabling new ways to study drug delivery. For instance, we can vary the shape or mechanical stiffness of a structure very precisely and see how that affects entry into cells.”

Here’s a look at what the technique does to a cancer cell:


Technique could also prove effective against other forms of cancer

For their research, Castro and Dr. Byrd utilized a pre-clinical model of acute myeloid leukemia (AML) that had developed resistance against the anthracycline chemotherapy drug daunorubicin. In these cases, when daunorubicin molecules entered an AML cell, the cell is able to recognize them and eject them through openings in the cell wall.

By hiding the drug in a molecular Trojan horse, however, they can sneak it past the defenses of the AML cell, allowing it to accumulate within the cell and cause it to die, Dr. Byrd explained. He added that it should be possible to design these structures so that they target only cancer cells and not other parts of the body, potentially leading to harmful side effects.

Their tests found that AML cells which had previously demonstrated resistance to daunorubicin would absorb the drug molecules if they were hidden inside tiny, rod-shaped DNA capsules. At 15 nanometers wide and 100 nanometers long, each capsule was roughly one-percent the size of the cells it was designed to infiltrate, but tough enough to only disintegrate fully once they were fully consumed by the cells and it was too late for them to be ejected.

“The way daunorubicin works is it tucks into the cancer cell’s DNA and prevents it from replicating,” explained postdoctoral researcher Christopher Lucas. “So we designed a capsule structure that would have lots of accessible DNA base-pairs for it to tuck into. When the capsule breaks down, the drug molecules are freed to flood the cell.”

The majority of the cells died within the first 15 minutes after they consumed to capsules, the study authors said. Dr. Byrd believes that the technique should work on most forms of drug-resistant cancer, pending additional research, and Castro added that he hopes to create an easy to use and inexpensive way to mass produce these DNA capsules.

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Featured image: cells on the left are pre-treatment, post-treatment on the right. Image credit: Ohio State University 

Release of new galactic map marks completion of ATLASGAL survey

A groundbreaking effort to study the cold universe, a collection of dust and gas a handful of degrees above absolute zero, has come to an end following the release of a new image of the Milky Way covering a 140-degree long, 3 degree-wide area of the sky.

The APEX Telescope Large Area Survey of the Galaxy (ATLASGAL) survey, which began collecting data nearly 10 years ago, was designed to map the entire area of the Galactic Plane visible from the southern hemisphere in submillimeter wavelengths for the first time.

This video gives you a sense of scale for the sheer size of this project:

In addition, it used the 12-meter APEX (Atacama Pathfinder Experiment) telescope, which is located 5,100 meters above sea level on the Chajnantor Plateau in Chile, to create maps of the sky in greater detail than was possible with previous space-based surveys, astronomers at the European Southern Observatory (ESO) explained Wednesday in a statement.

Thanks to the unique properties of the APEX telescope, the ATLASGAL survey was able to provide and in-depth look at how cold, dense gas is distributed along the plane of our galaxy, including areas of star formation located in the southern Milky Way, the ESO added.

This image of the Milky Way has been released to mark the completion of the APEX Telescope Large Area Survey of the Galaxy (ATLASGAL). The APEX telescope in Chile has mapped the full area of the Galactic Plane visible from the southern hemisphere for the first time at submillimetre wavelengths — between infrared light and radio waves — and in finer detail than recent space-based surveys. The APEX data, at a wavelength of 0.87 millimetres, shows up in red and the background blue image was imaged at shorter infrared wavelengths by the NASA Spitzer Space Telescope as part of the GLIMPSE survey. The fainter extended red structures come from complementary observations made by ESA's Planck satellite. Many of the most prominent objects are named and the parts of the galaxy that are shown in the three slices are indicated at the right.

Credit: ESO

Survey’s completion ‘opens up the possibility’ of new discoveries

The newly released images map an area of the sky four times larger than the first ones created using the APEX telescope nearly 10 years ago, and are said to also be of higher quality, as the team took a second look at some previously observed areas to obtain more uniform results across the entire survey area.

The ATLASGAL survey, which has to date already resulted in the publication of more than 65 scientific papers, used the APEX telescope’s Large Bolometer Camera (LABOCA) to measure incoming radiation by detecting slight increases in temperature, the ESO said. In addition, it can detect emissions from the cold, dark dust bands that obscure light from the sun.

The release of the new image brings the ATLASGAL survey to an end. Over the past decade, its data has helped detect emission spread over a large area of the sky, estimate the amount of dense gas located in the inner galaxy, and create a census of cold and massive gas clouds in parts of the galaxy where new stars are forming.

“ATLASGAL provides exciting insights into where the next generation of high-mass stars and clusters form,” said ATLASGAL scientist Timea Csengeri of the Max Planck Institute for Radio Astronomy (MPIfR) in Bonn, Germany. “By combining these with observations from Planck, we can now obtain a link to the large-scale structures of giant molecular clouds.”

“ATLASGAL has allowed us to have a new and transformational look at the dense interstellar medium of our own galaxy, the Milky Way,” the ESO’s Leonardo Testi added. “The new release of the full survey opens up the possibility to mine this marvelous dataset for new discoveries. Many teams of scientists are already using the ATLASGAL data to plan for detailed ALMA follow-up.”

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Image credit: ESO

New imaging technique can find Earth-like planets near their stars

The quest to find Earth-like planets (and extraterrestrial life) may have just gotten a huge boost by way of a newly-developed imaging technique.

Astrophysicists have long been on the lookout for planets where life may exist—very generally, those in a sweet spot of being close enough to a star so the planets are warm, but not too warm to support life. The only problem is, often these planets are difficult or impossible to see through a traditional telescope because the brightness of their star drowns out the tiny bit of light reflected by the planet—kind of like trying to see a firefly next to a lighthouse but much, much harder.

“Current instrument technology is very complex and expensive and still a ways off from achieving direct images of Earth-like planets,” added Florida Institute of Technology astrophysicist Daniel Batcheldor in a statement.

New solution to an old problem

But now there is new hope, according to a new paper in Publications of the Astronomical Society of the Pacific, as researchers led by Batcheldor have shown that something known as a charge injection device, or CID, might be a viable (and significantly less expensive) solution to this problem.

Image credit: Florida Institute of Technology

Some data taken from the CID system. Image credit: Florida Institute of Technology

A CID is used as a type of camera: It takes in and captures light, but it can capture light from objects that are tens of millions of time dimmer than other objects in the same picture—like a planet next to a bright star, for example.

The camera can do this because each of the camera’s pixels work independently from each other. So, when looking at a star, the pixels capturing the star get addressed and capture its light very quickly, while pixels representing something fainter near the star take more time to gather the object’s dimmer light.

“The CID is able to look at a very bright source next to a very faint source and not experience much of the image degradation you would normally experience with a typical camera,” said Batcheldor.

In the study, Batcheldor and several graduate students used Florida Tech’s 0.8-meter (2.6-foot) Ortega telescope were able to pick out objects in the glare of the brightest star in the night sky, Sirius. But not just any objects: Ones that were 70 million times dimmer, meaning CID is more than 1000 times better than a regular astronomical camera.

“If this technology can be added to future space missions, it may help us make some profound discoveries regarding our place in the universe,” said Batcheldor.

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Image credit: NASA

New dating technique shows multiple meteors struck the Earth 790,000 years ago

A new analysis of tektites, gravel-sized objects made of natural glass and formed from terrestrial debris ejected when meteorites collide with the Earth’s surface, has revealed that multiple cosmic impacts took place in various parts of the world approximately 790,000 years ago.

Dr. Mario Trieloff, a geoscientist at Heidelberg University in Germany, and his colleagues used a new, more accurate dating technique based on naturally-occurring isotopes to investigate rock glasses retrieved from various locations in Asia, Australia, Canada, and Central America.

As they report in a paper to be appear in the April 2016 edition of Geochimica et Cosmochimica Acta, the samples are all virtually identical in age, despite the fact that, in some cases, they have significantly different chemistry. This indicates that a series of separate impact events must have occurred at roughly the same time, the study authors explained in a statement.

picture of tektites used in the study

Some of the tektites used in the study. Credit: Heidelberg University

Tektites are formed when terrestrial material melts following a meteorite impact, is launched into the air and then hardens into glass, and Dr. Trieloff’s team said that they can determine when and where projectiles struck the planet’s surface, how often, and how large those objects were.

Natural disasters, lower surface temperatures would have followed

The researchers explained that scientists had long known about the existence of tektites in the Australasian region, from Indochina to southern Australia. Smaller rock glass samples called microtektites were also collected in deep-sea drill cores off the coast of Madagascar and in the Antarctic, and samples from Central America and Canada were analyzed as well.

Dr. Trieloff, lead author Dr. Winfried Schwarz and their fellow geoscientists used the 40Ar-39Ar dating method to analyze the decay of naturally occurring 40K isotope, and found that there must have been a cosmic impact approximately 793,000 years ago, plus or minus 8,000 years.

Tektites from Canada were similar in terms of chemical composition to those from Australia or the Antarctic, the authors said, suggesting that they may have traveled the same “flight routes,” provided the recovery sites were actually where the rock glass samples landed. The composition of the tektites recovered from Central America differed from the others, however.

“These tektites are clearly different in their chemical composition, and their geographical distribution also shows that they come from separate impacts,” said Dr. Schwarz. “Surprisingly our age estimates prove that they originated 777,000 years ago with a deviation of 16,000 years. Within the error margin, this matches the age of the Australasian tektites.”

“The distribution of the tektites and the size of the strewn field indicate that Earth-striking body was at least a kilometer in size and released an impressive one million megatons of TNT energy within seconds of impact,” the doctor added. Such an impact would have had dire consequences, as it would have caused widespread fires, earthquakes and/or tsunamis, and the amount of dust ejected into the atmosphere would have blocked sunlight and lowered surface temperatures.

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Image credit: Thinkstock

New one-step hydrocarbon fuel could help combat global warming

A new one-step process that converts carbon dioxide and water directly into liquid hydrocarbon could significantly limit global warming by removing CO2 from the atmosphere to produce fuel, chemists and engineers from the University of Texas at Arlington have discovered.

Furthermore, they claim that the process, which harnesses light, heat, and high pressure to create the sustainable fuel, would also release oxygen back into the planet’s atmosphere as a byproduct of the necessary chemical reaction, making it a win-win in terms of environmental impact.

As Frederick MacDonnell, interim chair of chemistry and biochemistry at UTA and co-principal researcher on the project, said in a statement, “Our process also has an important advantage over battery or gaseous-hydrogen powered vehicle technologies as many of the hydrocarbon products from our reaction are exactly what we use in cars, trucks and planes, so there would be no need to change the current fuel distribution system.”

MacDonnell and his colleagues demonstrated that carbon dioxide and water can be converted to liquid hydrocarbons and oxygen in a simple, one-step process using a photothermochemical flow reactor operating at 180 to 200 C and pressures up to 6 atmospheres. A paper detailing the team’s research was published Monday in the Proceedings of the National Academy of Sciences.

The goal is to produce ‘a sustainable solar liquid fuel’

“We are the first to use both light and heat to synthesize liquid hydrocarbons in a single stage reactor from carbon dioxide and water,” explained Brian Dennis, professor of mechanical and aerospace engineering at UTA and the other co-principal investigator of the project.

Dennis explained that the photochemical reaction is driven by concentrated light. The process generates high-energy intermediates and heat, which serves as the catalyst for thermochemical carbon-chain-forming reactions, allowing liquid hydrocarbons to be produced in a single step.

In their experiments, MacDonnell, Dennis and their colleagues used a hybrid photochemical and thermochemical catalyst based on titanium dioxide, a white powder that cannot absorb the entire visible light spectrum. The next step, they explained, will be to develop a photo-catalyst which is better suited to the solar spectrum so that they will be able to more effectively use other kinds of light to improve their chances of developing “a sustainable solar liquid fuel.”

Ultimately, the study authors hope to use parabolic mirrors to concentrate sunlight on the catalyst bed, which would enable them to provide both heat and photo-excitation for the process. If there were any excess heat left over from the reaction, it could be harnessed for other processes needed to produce solar fuel, such as product separation and water purification, the UTA team said.

MacDonnell and Dennis, who have received nearly $2.7 million in grants and corporate funding to study sustainable energy since 2012, are also working on a method to convert natural gas into usable high-grade diesel and jet fuel. Furthermore, MacDonnell has also working on a synthetic photosynthetic system that uses solar power to split water molecules into oxygen and hydrogen, allowing the later to be used as a clean-burning fuel.

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Image credit: University of Texas at Austin

NASA scientist claims we could cut Mars travel time to just three days

One of the biggest obstacles facing a proposed manned mission to Mars is the amount of time it would take a modern spacecraft to make the journey, but one NASA scientist says the agency is working on ways to significantly reduce how long it takes to get to the Red Planet.

As Philip Lubin, a physicist at the University of Santa Barbara Experimental Cosmology Group, explained in a recent NASA 360 video, researchers can propel particles at near light speed in laboratory conditions, but currently, spacecraft can only travel at a fraction of that velocity.

As a result, it currently takes the agency approximately eight months to send unmanned vehicles from Earth to Mars, forcing them to investigate whether or not the human body would be able to withstand such a long voyage. However, Lubin said, NASA is also working on new methods of propulsion that could theoretically cut the travel time to as little as three days.

‘No reason’ why the technology won’t live up to expectations

According to ScienceAlert, Lubin and his colleagues are developing a system where a spaceship with giant sails would be propelled to Mars using lasers. This “photonic propulsion” system would be similar to the solar sail concept proposed by The Planetary Society, but would harness the momentum of photons to move the craft through space.

Listen to Lubin explain the technology in this video:

Instead of relying on particles of light from the Sun, the design proposed by Lubin would use large Earth-based lasers as a source of photons, and while this might sound like something from a science-fiction movie, the UCSB physicist emphasizes that the system would use technology that is already readily available, and that the system would not be hard to upscale.

“There are recent advances that take this from science fiction to science reality,” he said. “There is no known reason why we cannot do this. There’s a road map… [and] the system is completely scalable, modularly. You can build it any size you want, from a tiny one to a gigantic one.”

Lubin, who authored a paper on the topic entitled “A Roadmap to Interstellar Flight,” said that such an engine would be able to propel a 100 kilogram robotic spacecraft to Mars in a matter of days, and that a manned mission could potentially be completed in one-eighth the current time. The system could even be used to travel to exoplanets up to 25 light years away, he added.

So how does it work? Even though photons lack mass, they possess both energy and momentum, the researchers explained. When they bounce off of an object like a big, reflective sail, some of the momentum is transferred. That momentum could be used to accelerate a spacecraft – at least in theory, as Lubin and his colleagues have yet to actually put their technology to the test.

However, we shouldn’t have to wait too much longer to learn if the photonic propulsion system can deliver on its inventors’ claims. NASA awarded a proof-of-concept grant to Lubin’s team in 2015 so that they could demonstrate whether or not the technology could be used for space travel and ScienceAlert is confident that they be able to deliver some results in the near future.

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Image credit: NASA

Astronomers discover 300,000-light-year-long gas tail stretching from galaxy

Astronomers have found an extraordinary trail of gas greater than 300,000 light years across originating from a nearby galaxy called NGC 4569, according to a report in Astronomy & Astrophysics.
The tail is comprised of hydrogen gas, the material new stars are born from, and is five times longer than the galaxy itself.
International Centre for Radio Astronomy Research astrophysicist Luca Cortese, who is part of the study team, said researchers have known that the galaxy NGC 4569 held less gas than expected but they couldn’t see where it went.
“We didn’t have the smoking gun, the clear evidence of direct removal of gas from the galaxy,” he said in a statement. “Now, with these observations, we’ve seen a huge amount of gas that creates a stream trailing behind the galaxy for the first time.
“What’s very nice is that if you measure the mass of the stream, it’s the same amount of gas that is missing from the galaxy’s disc,” Cortese added.
NGC 4569 is located in the Virgo cluster, 55 million light years away, and moving through the cluster at approximately 750 miles a second. Cortese said this motion strips gas from the galaxy.
“We know that big clusters of galaxies trap a lot of hot gas,” he said. “So when a galaxy enters the cluster it feels the pressure of all the gas, like when you feel the wind on your face, and that pressure is able to strip matter away from the galaxy.”
The study team’s finding was made when they used a super-sensitive camera on the Canada France Hawaii Telescope to observe NGC 4569 for more time than ever before.
Cortese said NGC 4569 might be the first of many galaxies discovered to have long tails of gas stretching out from them.
“It’s pretty exciting because this was just a pilot and we only targeted the brightest spiral galaxy in the Virgo cluster,” he said. “We were amazed by what we got… this is really promising because it means it’s very likely we’ll find similar features in many other galaxy clusters.”
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Feature Image: Image of galaxy tail. Credit: Courtesy of International Centre for Radio Astronomy Research (ICRAR)

Scientists successfully sequence Zika virus genome; confirm it causes microcephaly

Brazilian scientists have successfully sequenced the genome of the Zika virus, confirming that it causes microcephaly in the process, according to the state media outlet Agencia Brasil.
The research team, from the Federal University of Rio de Janeiro (UFRJ), sequenced Zika viruses found in the amniotic fluid of pregnant women who tested positive for the disease and in the brains of fetuses with microcephaly. The team said their work should explain the unusual behavior of the virus.
“What we know now may help us understand why the virus has chosen children’s brain cells over those of adults—the pregnant women,” said team member Renato Santana.
Brazils’ official health ministry said most of women who gave birth to babies diagnosed with “microcephaly and/or changes in the central nervous system suggesting congenital infection” had the virus. The Brazilian scientists said they are looking into the possibility the Zika virus can cause other types of developmental problems.
The Zika virus only causes symptoms in about one-fifth of those who are infected. The major concern associated with the virus, however, is that it causes microcephaly, where babies are born with small heads and impaired cognitive abilities.
The virus is thought to have originated in Africa and spread to South America, where a lack of exposure to it has led to a pandemic. The Centers for Disease Control and Prevention has counted 27 countries or territories in the Western Hemisphere with active transmission of the Zika virus.
Colombia has seen a sharp rise in the amount of Zika cases, which now number greater than 37,000, cases, Colombian officials said. There are nearly 6,400 pregnant women who are among the overall quantity of Zika cases, now standing at more than 37,000, Colombia’s National Institute of Health said in a press release. A minimum of 30,000 cases have been validated through clinical and laboratory tests. Last week, there were nearly 5,000 new reported cases, according to government officials.
The Brazilian Ministry of Health has reported that country’s amount of Zika cases as between 490,000 and nearly 1.5 million, The World Health Organization said Brazilian officials have stopped counting new cases of the Zika virus.
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Feature Image: Thinkstock

The neuroscience behind Buddhist enlightenment

To many non-believers, Buddhism is the “good” kind of religion, one that doesn’t start wars and has powerful things to say on the mindfulness and mental self control we all seek by one method or another.

RedOrbit spoke to Dr. Rick Hanson, psychologist, Senior Fellow of the Greater Good Science Center at UC Berkeley, and New York Times best-selling author, to discuss the science of what was going on inside Buddha’s brain, and how we might just be able to attain a little of his enlightenment for ourselves.

Dr. Hanson begins by stressing that the word “enlightenment” has to be defined carefully.

“The word enlightenment has two kinds of meaning,” he says. “One is in an entirely secular frame. In the Buddhist tradition, it’s very psychological operationalized as a mind, a nervous system, that’s no longer capable of any kind of sustained greed, hatred or delusion.”

Pleasant things can still be experienced, he expands, but enlightenment means we don’t get attached to the experience. At the same time, we are aware of unpleasantness, but it doesn’t result in anger or hatred.

Dr. Hanson is keen to point out that talking about the science behind the thinkings of such a prominent religious figure as the Buddha should not necessarily be seen as a wholesale replacement for ideas of mysticism and transcendence. However, he says: “Buddhism in its roots is very practical, very down-to-earth, and maps very well to modern neuropsychology.”

He continues: “There are certain psychological states that seem associated with the upper reaches of human potential, if not enlightenment altogether.”

Probably the best example of this is equanimity (“a state of psychological stability and composure which is undisturbed by experience of or exposure to emotions, pain, or other phenomena that may cause others to lose the balance of their mind,” as defined by Wikipedia).

Being connected – “at one” with things, to use a Buddhist term – is a better definition of enlightenment than is being aloof from and unaffected by everything. People with great equanimity are fully engaged in life; they are compassionate and loving; they can focus attention extremely well (or withdraw when applying it is not healthy), and have a strong sense of being connected to material reality – to humanity and nature, Dr. Hanson explains.

Such qualities, of course, sound very similar to those supposedly held by many of the great religious leaders, but in his book, Buddha’s Brain: The Practical Neuroscience of Happiness, Love & Wisdom, Dr. Hanson explains how neuropsychology makes it perfectly possible for regular people to have these qualities even at superior levels, rather than them being the reserve only of a blessed few.

What goes on in an enlightened brain?

So how can regular people improve these qualities in themselves? First, a brief overview of the emotional hardware of the brain, and of biological evolution, is needed.

“The brain is built like a house with three floors, from the bottom up,” Dr. Hanson explains. “The reptilian brain stem is at the bottom; on top of that, beginning around 250 million years ago, we have the subcortex, which is loosely associated with the mammalian stage of evolution. And finally we have the primate level,” which is the most advanced: the cerebral cortex.

“We are walking around with a vast, ancient zoo and museum inside us,” he adds. “We diverged from fish some 350-450 million years ago, but some of the brain similarities are still there, making sound, for example.”

Within the subcortex are the two amygdalas, and they are concerned with emotional reactions and threat detection. This part of the brain is also highly identifiable with our ancient ancestors, and yet can be trained to be even more highly developed than it has become in most humans.

“Research shows that while very equanimous people are not numb or apathetic – they can be passionate about their football team or angry about injustice – their emotional responses can be controlled,” Dr. Hanson says. “This is marked by the amygdala becoming increasingly regulated from the top down, in the cerebral cortex. The alarm bells don’t ring as readily or as loudly, and people recover more rapidly.”

This is process is aided by oxytocin, informally referred to as the “love hormone”.

Techniques for different aspects of enlightenment

So how do we do make our brains do this?

“Repeated internalization of positive emotions” is important, says Hanson. This doesn’t have to be in a “giddy, new age kind of way”, but in authentic ways such as taking pleasure from simple things like friendships or time with our family (this is where the oxytocin comes in), or learning a new thing; accomplishing something. Sublime emotions like looking at the stars or nature also do the job, especially for science geeks such as myself!”

Labeling experiences assists internalization, and this applies with negative things too. Jotting down one word about how we are feeling (“angry”, “worried”, “competitive”, for example) helps us to take control of our emotions. This helps to regulate activity in the amygdala.

Staying with a nice moment a little longer, indulging in it, also helps. We shouldn’t over-analyze; it’s just mental noting.

“It’s these little things that add up to big things. It’s not a magic cure, which is why it’s credible,” Dr. Hanson says. “For those who engage in some form of psychological practice and mental training, there is more and more evidence of an underlying neural signature for the results of the practice; an underlying change in the nervous system. People really can become more enlightened.”

Could Buddha’s purported enlightenment, then, be seen in its most basic definition as extreme brain training?

“Working within the natural frame, yeah, that’s how I see it,” says Dr. Hanson. “It’s important to be clear about the purpose. Brain training could also be used to become the world’s greatest sniper. I think the Buddhism journey was motivated by a desire to be free from suffering, as well as emphasizing virtue and kindness.”

Enlightenment can’t be explained by any one factor, he adds, but the neurological signatures of what today might be better referred to as equanimity certainly go a long way towards explaining it.

Where focus of attention is concerned, the neurological signature is a build up of neuro circuits anterior cingulate cortex. This is where meditation comes in, with the build-up being added by techniques famously associated with it. Breathing techniques, or even concentration on one word of your choice being repeated over and over.

If striving for virtue and kindness, Dr. Hanson says he likes to practice a technique called “hit and run compassion”, in which a total stranger is chosen on the street, and is secretly and silently wished well for a few seconds.

The final Buddha-like quality we may wish to try and attain is a sense of connection with all things. This is more complex and profound than the other aspects, Dr. Hanson believes, but plenty of regular people do seem to possess such a quality. It’s achieved when allocentric perceptual circuits in the brain gives us an impersonal perspective on things, as opposed to the egocentric perspective. One simple way to develop allocentric neural activity is to lift our gaze to the horizon or up to the sky more often – following the path of a bird, for example – which helps us to get a broader perspective on things.

“The word ‘Buddha’ just means ‘one who knows’ or ‘one who sees clearly’, so we’re all capable of having a ‘Buddha brain’,” Dr. Hanson concludes. “Some of us will be more motivated to achieve it than others, just as some people will be more motivated to become great Olympians or football players, but it is achievable. Buddhist psychology maps the best to modern, Western science of any contemplative traditions, because it tends to be at bottom really quite secular. It’s not metaphysical – it’s direct experience based.”

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Feature Image: Thinkstock

Impact of water on the Martian surface revealed in new images

Images captured last week by the European Space Agency’s Mars Express orbiter revealed the impact of flooding on a large chunk of the planet’s landscape, including the western portion of the Arda Valles, a dendritic drainage system north of Holden Crater.

Arda Valles, which is 260 kilometers north of the crater and close to Landon Valles, was once home to large quantities of water flowing from the southern highlands, the ESA explained in a statement. This water helped carve Ladon Valles, a river valley located within the Margaritifer Sinus quadrangle region of the Red Planet, and formed a pond in a large basin nearby.

martian surface

Arda Valles topography. Credit: ESA/DLR/FU Berlin, CC BY-SA 3.0 IGO

In one of the new images captured by Mars Express, the dendritic drainage pattern of the valley is clearly visible, and you can see where several individual streams merged together before they continued down into the smooth-floored impact basin. In addition, a large mound with an 8.5km wide impact crater at its base can be seen in the upper center of one of the new photographs.

The agency explained that this mount could be the remains of an older impact basin, but added that it may have also been affected by sediments transported by the streams that once surrounded it. Those sediments could have accumulated into a fan-shaped deposit or an alluvial fan.

martian surface

This context image shows part of the Arda Valles region on Mars, a dendritic drainage system located 260 km north of Holden Crater. (Credit: NASA MGS MOLA Science Team)

Clay minerals, essential for life, also visible in the new photos

In addition, the new images depict a larger, 25km wide impact crater located towards the center-right that also appears to have been filled by muddy sediments. Those sediments likely collapsed into the cracked and chaotic crater floor, with its nodules probably indicating the previous levels of the sediments that had partially filled up the hole.

The upper right portion of one image shows a region where the surface was cracked, breaking up into a series of large polygons that ESA scientists believe may have been associated with the loss of subterranean ice and the long-term evaporation of water previously found in the vicinity.

martian surface

This perspective view in Arda Valles was generated from the main camera’s stereo channels on ESA’s Mars Express. The image focuses on a 25 km-wide impact crater filled with sediments, that have subsequently collapsed into chaotic terrain. The jumbled nodules in the crater rim probably indicate the former level of the infilling sediments. A number of fracture-like features appear to extend out to the smoother basin floor to the right. They could be a later manifestation of stresses due to subsidence or compaction of surface materials. (Credit: ESA)

Fracture-like features visible in the basin’s smooth floor are also believed to be linked to surface stress caused by the compaction of sediments in the basin, and some of the fractures seem to join the central crater to the smoother floor of the basin, the agency said. These features may be more recent manifestation of stresses caused by subsidence or surface material compaction.

Furthermore, in the lower center of the image, just above the bottom-most crater and towards the end of the dendritic channels, researchers have identified a series of light-colored sediment layers as clay minerals. Clay minerals, also known as hydrous aluminium phyllosilicates, typically form in the presence of water and are believed to play a key role in the origin of biological life.

martian surface

This anaglyph image showing part of the Arda Valles region on Mars provides a 3D view of the landscape when viewed using stereoscopic glasses with red–green or red–blue filters. (Credit: ESA/DLR/FU Berlin, CC BY-SA 3.0 IGO)

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Feature Image: Arda Valles. Credit: ESA/DLR/FU Berlin, CC BY-SA 3.0 IGO

Researchers have developed the first-ever bendable smartphone

Calling it “a completely new way” of physically interacting with mobile devices, Roel Vertegaal, director of the Human Media Lab at Queen’s University, and his colleagues have developed what they are hailing as the first ever full-color, high-resolution, wireless flexible smartphone.

The device, which has been dubbed ReFlex, enables users to experience physical tactile feedback while interacting with various apps by bending it, the designers explained recently in a statement. A video shows the device being bent in different directions to turn pages in a book backward and forwards, and the popular game Angry Birds being played by flexing the phone.

“When this smartphone is bent down on the right, pages flip through the fingers from right to left, just like they would in a book. More extreme bends speed up the page flips,” Dr. Vertegaals said. “Users can feel the sensation of the page moving through their fingertips via a detailed vibration of the phone. This allows eyes-free navigation, making it easier for users to keep track of where they are in a document.”

ReFlex is based on a high definition 720p LG Display Flexible OLED touch screen powered by an Android 4.4 “KitKat” board mounted to the side of the display. Bend sensors installed behind the display can detect the force being used to bend the screen, and a haptic actuator recreates the sense of touch. Combined, they can be used as input devices for various applications.

Device could be commercially available by the year 2021

In addition, ReFlex is said to be equipped with a voice coil which allows the phone to simulate a variety of forces, including friction, through vibrations in the display screen. Combined with the use of passive force feedback experienced when the display is bent, this enables a highly realistic simulation of actual physical forces while the user interacts with virtual objects, they said.

“This allows for the most accurate physical simulation of interacting with virtual data possible on a smartphone today,” explained Dr. Vertegaal. “When a user plays the ‘Angry Birds’ game with ReFlex, they bend the screen to stretch the sling shot. As the rubber band expands, users experience vibrations that simulate those of a real stretching rubber band. When released, the band snaps, sending a jolt through the phone and sending the bird flying across the screen.”

He and his colleagues officially unveiled the prototype model of the ReFlex smartphone during the Conference on Tangible Embedded and Embodied Interaction (TEI) in The Netherlands last week. They have also published a study detailing how the device works, which can currently be viewed online, and predict that bendable mobile devices could be available to consumers within the next five years.

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Feature Image: User navigating pages by bending the smartphone; feels pages flip through fingers. (Credit: Human Media Lab)

 

Apollo 10 astronauts heard unexplained ‘outer-space type’ music on dark side of moon

While orbiting the dark side of the moon during their 1969 voyage, Apollo 10 astronauts Tom Stafford, John Young, and Eugene Cernan described hearing unusual “outer-space type” music, and now, nearly four decades later, NASA has finally released audio of those sounds.

Transcripts of the conversation where Young and Cernan discussed hearing a “whistling sound” while on the far side of the moon, beyond the range of Earth-based radio transmissions, had been released eight years ago, according to CNN.com. However, a recording of their discussion and a clip of the mysterious sound itself is only now being released to the general public.

On the recording, Cernan is heard asking Young if he heard a “whistling sound.” Young replied that it was “weird music” and sounded like “outer-space type music” as Cernan pondered what it might have been, and what could have caused it. The event was so bizarre that the team had even wondered whether or not they should let their NASA superiors know about it, CNN said.

The noise continued through nearly the entire hour that the capsule spend on the far side of the moon, and according to the Daily Mail, the recording was shelved by NASA until 2008, when it was declassified and the transcript was released. Now the recording itself has resurfaced, thanks to an upcoming episode of the Science Channel program NASA’s Unexplained Files.

So just what was that ‘outer-space’ music, anyway?

To get the obvious joke out of the way: No, it wasn’t Pink Floyd – as the Daily Mail pointed out, Dark Side of The Moon wasn’t even released until 1973. So just what was this otherworldly song that Cernan, Young, and Stafford heard. Is it proof of alien life or advanced lunar civilizations?

Sadly, no. As is often the case when it comes to “unexplained” phenomena like this, it turns out that there’s a rather easy explanation for it. On the TV show, a NASA technician explained that the noise is nothing more than “radios in the two spacecraft [the lunar module and the command module] were interfering with each other” and producing the whistling sound.

Of course, not everyone buys that explanation. As Apollo 15 astronaut Al Worden said during the broadcast, “The Apollo 10 crew was very used to the kind of noise that they should be hearing. Logic tells me that if there was something recorded on there, then there was something there.”

The program offers another possible explanation – that interference from a magnetic field or the atmosphere might have caused the sound – before allowing experts to promptly shoot both of the theories down by pointing out that the moon lacks a magnetic field and does not have enough of an atmosphere to cause such issues to occur.

However, Apollo 11 pilot Michael Collins backs the official explanation, according to CNN. He said that he heard similar noises while in orbit around the moon, but gave it little thought because he had been forewarned that it could happen. Were he not prepared, “it would have scared the hell out of me,” he said. “Fortunately the radio technicians… had a ready explanation for it: It was interference between the LM’s and Command Module’s VHF radios,” Collins said, noting that the sound only began when both radios had been turned on and the vehicles were in close proximity to one another.

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Feature Image: The Apollo 10 command module Charlie Brown is seen from the lunar module Snoopy after separation in lunar orbit. Credit: NASA

Scientists redefine animal classification system; change confirmed by genetics

The classification system for animals* has been hotly debated and frequently changed since it was created 300 years ago, but now researchers have actually found a genetic basis which confirms that part of the system we use today is actually pretty accurate—and they think this part can be defined even more specifically down to the genetic level.

An international team led by Professor Itai YanaAi of the Technion-Israel Institute of Technology Department of Biology made the discovery after using an extraordinarily powerful technique known as CEL-Seq. CEL-Seq monitors individual cells for their gene activity (as detected via mRNA)—and they applied it across 10 different species, with CEL-Seq being applied to 70 embryos per species.

In particular, they were interested in whether the animal classification of phylum—which separates animals into groups according to their body plans—is actually a useful tool for placing animals into groups, as well as what genetic attributes are the same and different between the different phyla.

Graphic of different animals during development

Credit: American Technion Society

“We selected species representing ten different animal phyla [of the 35 total phyla],” said Yanai in a statement. “For each phyla we determined the gene expression profile of all genes from the development of the fertilized egg to the free-living larvae. We found a surprising pattern of gene expression conservation in all species occurring at a pivotal, transitional period in development.”

Different bodies, different expressions

According to the paper, which is published in Nature, they actually discovered that while the animals they selected were extremely different in their body plans—there were fish, worms, flies, water bears, sponges, and more—all of them expressed two distinct patterns of gene expression (i.e. different patterns of turned on genes) as they developed from a fertilized egg into a full organism: One which creates a general template of an animal, and another which turns it into an animal of a specific species.

With this new knowledge, scientists have a new proposed definition for a phylum, which (in a jargon-heavy way) is defined as “a set of species sharing the same signals and transcription factor networks during the mid-developmental transition.”

Which is to say, they have made the definition for phylum more specific than organisms merely sharing a similar body plan. Now, they suggest that organisms in the same phylum also share unique genetic transition as they develop, which changes the levels at which genes are expressed and gives them unique body features.

“The transition we identified may be a hallmark of development only in animals,” the researchers wrote. “Or, future work may show that this is a general characteristic of development in all multicellular life.”

*For those of you who don’t remember biology: kingdom, phylum, class, order, family, genus, species is how we go from a general group of organisms, like the animal kingdom, to a specific organism, like Homo sapiens

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Image credit: Thinkstock